Published in J Biol Chem on May 18, 2011
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RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis. Mol Biol Cell (2009) 1.03
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microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. Cancer Res (2008) 4.81
Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain. Mol Cell (2006) 4.36
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem (2004) 4.32
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res (2009) 3.57
Grb2 regulates internalization of EGF receptors through clathrin-coated pits. Mol Biol Cell (2003) 2.58
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RNA interference screen reveals an essential role of Nedd4-2 in dopamine transporter ubiquitination and endocytosis. J Neurosci (2006) 2.08
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microRNA-34a is tumor suppressive in brain tumors and glioma stem cells. Cell Cycle (2010) 1.90
Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol (2010) 1.90
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Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. Mol Biol Cell (2002) 1.77
Constitutive and protein kinase C-induced internalization of the dopamine transporter is mediated by a clathrin-dependent mechanism. Traffic (2005) 1.76
Three-chromophore FRET microscopy to analyze multiprotein interactions in living cells. Nat Methods (2004) 1.74
Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor. J Biol Chem (2002) 1.63
Conversion of the monomeric red fluorescent protein into a photoactivatable probe. Chem Biol (2005) 1.63
Oligomerization of dopamine transporters visualized in living cells by fluorescence resonance energy transfer microscopy. J Biol Chem (2003) 1.62
Endocytosis of receptor tyrosine kinases. Cold Spring Harb Perspect Biol (2013) 1.57
Uncovering MicroRNA and Transcription Factor Mediated Regulatory Networks in Glioblastoma. PLoS Comput Biol (2012) 1.54
Three ubiquitin conjugation sites in the amino terminus of the dopamine transporter mediate protein kinase C-dependent endocytosis of the transporter. Mol Biol Cell (2006) 1.50
Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis. Mol Biol Cell (2005) 1.49
Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells. Neuro Oncol (2010) 1.41
Enhanced ubiquitylation and accelerated degradation of the dopamine transporter mediated by protein kinase C. J Biol Chem (2005) 1.32
Rapid regulation of the dopamine transporter: role in stimulant addiction? Neuropharmacology (2004) 1.32
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Visualization of Rab5 activity in living cells by FRET microscopy and influence of plasma-membrane-targeted Rab5 on clathrin-dependent endocytosis. J Cell Sci (2003) 1.27
Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. J Neurosci (2010) 1.26
The role of EGF receptor ubiquitination in regulating its intracellular traffic. Traffic (2011) 1.23
Multiple molecular determinants in the carboxyl terminus regulate dopamine transporter export from endoplasmic reticulum. J Biol Chem (2004) 1.16
Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues. J Neurosci (2009) 1.16
Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes. J Biol Chem (2010) 1.13
Trafficking of dopamine transporters in psychostimulant actions. Semin Cell Dev Biol (2009) 1.11
Tyrosine phosphorylation of the beta2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the epidermal growth factor receptor trafficking. J Biol Chem (2003) 1.10
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Agents with selective estrogen receptor (ER) modulator activity induce apoptosis in vitro and in vivo in ER-negative glioma cells. Cancer Res (2004) 1.09
microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma. Cancer Res (2014) 1.07
Calmodulin regulates intracellular trafficking of epidermal growth factor receptor and the MAPK signaling pathway. Mol Biol Cell (2002) 1.05
Differential subcellular distribution of endosomal compartments and the dopamine transporter in dopaminergic neurons. Mol Cell Neurosci (2010) 1.04
Endosomal targeting of MEK2 requires RAF, MEK kinase activity and clathrin-dependent endocytosis. Traffic (2008) 1.04
Protein kinase C-dependent ubiquitination and clathrin-mediated endocytosis of the cationic amino acid transporter CAT-1. J Biol Chem (2011) 1.03
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RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis. Mol Biol Cell (2009) 1.03
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Live-cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis. J Cell Sci (2013) 0.91
Protein kinaseCdelta-calmodulin crosstalk regulates epidermal growth factor receptor exit from early endosomes. Mol Biol Cell (2004) 0.89
Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness. Synapse (2013) 0.87
A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival. Neuro Oncol (2013) 0.87
Flotillins regulate membrane mobility of the dopamine transporter but are not required for its protein kinase C dependent endocytosis. Traffic (2013) 0.87
Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition. Clin Cancer Res (2013) 0.86
Angiogenic inhibition in high-grade gliomas: past, present and future. Expert Rev Neurother (2012) 0.86
Phase II trial of triple tyrosine kinase receptor inhibitor nintedanib in recurrent high-grade gliomas. J Neurooncol (2014) 0.85
A bifunctional converter: fluorescein quenching scFv/fluorogen activating protein for photostability and improved signal to noise in fluorescence experiments. Bioconjug Chem (2014) 0.84
Bevacizumab in combination with irinotecan for patients with recurrent glioblastoma multiforme. Nat Clin Pract Oncol (2008) 0.84
Cyclin-dependent kinase 5 inhibitors: inhibition of dopamine transporter activity. Mol Pharmacol (2009) 0.84
Alpha-secretase inhibition reduces human glioblastoma stem cell growth in vitro and in vivo by inhibiting Notch. Neuro Oncol (2012) 0.84
Recruitment of Uev1B to Hrs-containing endosomes and its effect on endosomal trafficking. Exp Cell Res (2010) 0.83
Micro-masters of glioblastoma biology and therapy: increasingly recognized roles for microRNAs. Neuro Oncol (2014) 0.81
The relationship between ER-multivesicular body membrane contacts and the ESCRT machinery. Biochem Soc Trans (2012) 0.80
Visualization of Rab5 activity in living cells using FRET microscopy. Methods Enzymol (2005) 0.80
Neuro-oncology: Five new things. Neurol Clin Pract (2013) 0.78
Signal Transduction Pathways Mediated by Secreted and Non-secreted Forms of intact Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) and its 1-97 N-terminal Fragment in PC-3 Human Prostate Cancer Cells. J Cancer Ther (2013) 0.77
Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity. FEBS J (2015) 0.76
Improved precision of proteomic measurements in immunoprecipitation based purifications using relative quantitation. Anal Chem (2013) 0.76
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