Downregulation of CD4 by human immunodeficiency virus type 1 Nef is dependent on clathrin and involves direct interaction of Nef with the AP2 clathrin adaptor.

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Published in J Virol on January 31, 2007

Authors

Rittik Chaudhuri1, O Wolf Lindwasser, William J Smith, James H Hurley, Juan S Bonifacino

Author Affiliations

1: Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, Bldg. 18T, Rm. 101, National Institutes of Health, Bethesda, MD 20892, USA.

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Hybrid structural model of the complete human ESCRT-0 complex. Structure (2009) 1.23

Solution structure of the ESCRT-I complex by small-angle X-ray scattering, EPR, and FRET spectroscopy. Proc Natl Acad Sci U S A (2011) 1.22

Crystal structure of the catalytic core of inositol 1,4,5-trisphosphate 3-kinase. Mol Cell (2004) 1.22

Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1. Dev Cell (2003) 1.22

Ubiquitin binding and conjugation regulate the recruitment of Rabex-5 to early endosomes. EMBO J (2008) 1.21

Signal-mediated, AP-1/clathrin-dependent sorting of transmembrane receptors to the somatodendritic domain of hippocampal neurons. Neuron (2012) 1.20

The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes, and lysosomes. Blood (2002) 1.20

SPG20 protein spartin is recruited to midbodies by ESCRT-III protein Ist1 and participates in cytokinesis. Mol Biol Cell (2010) 1.20

In vitro reconstitution of the ordered assembly of the endosomal sorting complex required for transport at membrane-bound HIV-1 Gag clusters. Proc Natl Acad Sci U S A (2012) 1.19

Assembly of the biogenesis of lysosome-related organelles complex-3 (BLOC-3) and its interaction with Rab9. J Biol Chem (2010) 1.19

Basolateral sorting of the coxsackie and adenovirus receptor through interaction of a canonical YXXPhi motif with the clathrin adaptors AP-1A and AP-1B. Proc Natl Acad Sci U S A (2012) 1.18