Published in PLoS One on June 24, 2011
Danazol Treatment for Telomere Diseases. N Engl J Med (2016) 3.39
Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Mol Psychiatry (2012) 2.37
Omega-3 fatty acids, oxidative stress, and leukocyte telomere length: A randomized controlled trial. Brain Behav Immun (2012) 1.76
The roles of senescence and telomere shortening in cardiovascular disease. Nat Rev Cardiol (2013) 1.48
The telomere lengthening conundrum--artifact or biology? Nucleic Acids Res (2013) 1.38
Early life stress and telomere length: investigating the connection and possible mechanisms: a critical survey of the evidence base, research methodology and basic biology. Bioessays (2012) 1.23
Tracking and fixed ranking of leukocyte telomere length across the adult life course. Aging Cell (2013) 1.17
Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis. PLoS One (2014) 1.17
Measuring telomere length and telomere dynamics in evolutionary biology and ecology. Methods Ecol Evol (2014) 1.10
Longitudinal association of telomere length and obesity indices in an intervention study with a Mediterranean diet: the PREDIMED-NAVARRA trial. Int J Obes (Lond) (2013) 1.02
Red blood cell size is inversely associated with leukocyte telomere length in a large multi-ethnic population. PLoS One (2012) 0.97
Leukocyte telomere length in the Finnish Diabetes Prevention Study. PLoS One (2012) 0.95
Leukocyte telomere dynamics in the elderly. Eur J Epidemiol (2013) 0.92
Markers of cellular senescence. Telomere shortening as a marker of cellular senescence. Aging (Albany NY) (2016) 0.88
Lifelong leukocyte telomere dynamics and survival in a free-living mammal. Aging Cell (2015) 0.84
Independent and combined effects of dietary weight loss and exercise on leukocyte telomere length in postmenopausal women. Obesity (Silver Spring) (2013) 0.83
The telomere lengthening conundrum - it could be biology. Aging Cell (2016) 0.82
Telomere length increase after weight loss induced by bariatric surgery: results from a 10 year prospective study. Int J Obes (Lond) (2015) 0.82
Association between informal caregiving and cellular aging in the survey of the health of wisconsin: the role of caregiving characteristics, stress, and strain. Am J Epidemiol (2014) 0.82
Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies. Sci Rep (2016) 0.81
Association of relative telomere length with progression of chronic kidney disease in two cohorts: effect modification by smoking and diabetes. Sci Rep (2015) 0.81
Seasonal variation of peripheral blood leukocyte telomere length in Costa Rica: A population-based observational study. Am J Hum Biol (2014) 0.81
Telomere length in relation to immunological parameters in patients with renal cell carcinoma. PLoS One (2013) 0.80
Telomere length attrition and chronic periodontitis: an ARIC Study nested case-control study. J Clin Periodontol (2014) 0.79
Physical Activity, Physical Fitness, and Leukocyte Telomere Length: The Cardiovascular Health Study. Med Sci Sports Exerc (2015) 0.79
Alterations in leukocyte telomere length in workers occupationally exposed to benzene. Environ Mol Mutagen (2014) 0.78
Leukocyte Telomere Length in the Neonatal Offspring of Mothers with Gestational and Pre-Gestational Diabetes. PLoS One (2016) 0.77
Prospective study of telomere length and LINE-1 methylation in peripheral blood cells: the role of B vitamins supplementation. Eur J Nutr (2015) 0.77
Effect of intensive exercise in early adult life on telomere length in later life in men. J Sports Sci Med (2015) 0.76
Resistance training and redox homeostasis: Correlation with age-associated genomic changes. Redox Biol (2016) 0.76
Predicting Survival from Telomere Length versus Conventional Predictors: A Multinational Population-Based Cohort Study. PLoS One (2016) 0.76
Long telomeres in blood leukocytes are associated with a high risk of ascending aortic aneurysm. PLoS One (2012) 0.76
Circulating cell-free DNA, telomere length and bilirubin in the Vienna Active Ageing Study: exploratory analysis of a randomized, controlled trial. Sci Rep (2016) 0.75
Detecting telomere elongation in longitudinal datasets: analysis of a proposal by Simons, Stulp and Nakagawa. PeerJ (2017) 0.75
Basic Biology of Oxidative Stress and the Cardiovascular System: Part 1 of a 3-Part Series. J Am Coll Cardiol (2017) 0.75
Cigarette smoking and telomere length: A systematic review of 84 studies and meta-analysis. Environ Res (2017) 0.75
Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc (2008) 62.52
Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A (2004) 12.89
Genetic determination of telomere size in humans: a twin study of three age groups. Am J Hum Genet (1994) 7.04
Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study. Lancet (2007) 6.57
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol (2006) 5.28
Telomere dysfunction: a potential cancer predisposition factor. J Natl Cancer Inst (2003) 5.09
White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol (2003) 5.04
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. J Exp Med (1999) 4.27
The rate of telomere sequence loss in human leukocytes varies with age. Proc Natl Acad Sci U S A (1998) 4.17
Extensive allelic variation and ultrashort telomeres in senescent human cells. Nat Genet (2003) 3.77
The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med (2008) 3.68
Telomere length is paternally inherited and is associated with parental lifespan. Proc Natl Acad Sci U S A (2007) 3.67
Telomere shortening in atherosclerosis. Lancet (2001) 3.65
Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension (2000) 3.32
Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay. Int J Epidemiol (2009) 2.87
Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol (2008) 2.86
Psychological and metabolic stress: a recipe for accelerated cellular aging? Hormones (Athens) (2009) 2.61
Telomere length assessment: biomarker of chronic oxidative stress? Free Radic Biol Med (2007) 2.47
Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer. Carcinogenesis (2005) 2.47
Estrogen activates telomerase. Cancer Res (1999) 2.41
Telomeric length and telomerase activity vary with age in peripheral blood cells obtained from normal individuals. Hum Genet (1998) 2.27
The individual blood cell telomere attrition rate is telomere length dependent. PLoS Genet (2009) 2.17
Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study. PLoS One (2010) 2.10
Telomere length and heredity: Indications of paternal inheritance. Proc Natl Acad Sci U S A (2005) 2.10
The nature of telomere fusion and a definition of the critical telomere length in human cells. Genes Dev (2007) 1.88
Telomere length is associated with obesity parameters but with a gender difference. Obesity (Silver Spring) (2008) 1.87
Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction. Arterioscler Thromb Vasc Biol (2008) 1.78
Replicative aging, telomeres, and oxidative stress. Ann N Y Acad Sci (2002) 1.74
Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule. J Gerontol A Biol Sci Med Sci (2011) 1.72
Telomere dysfunction in peripheral lymphocytes as a potential predisposition factor for renal cancer. J Urol (2007) 1.65
Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res (2002) 1.64
The pattern of chromosome-specific variations in telomere length in humans is determined by inherited, telomere-near factors and is maintained throughout life. Mech Ageing Dev (2003) 1.33
Large-scale parent-child comparison confirms a strong paternal influence on telomere length. Eur J Hum Genet (2009) 1.33
Telomere length as a biological marker in malignancy. Biochim Biophys Acta (2009) 1.19
Allele-specific relative telomere lengths are inherited. Hum Genet (2006) 1.18
Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patterns. Br J Haematol (2000) 1.14
Telomere maintenance in human B lymphocytes. Br J Haematol (2002) 1.08
Telomere length dynamics in normal individuals and in patients with hematopoietic stem cell-associated disorders. Ann N Y Acad Sci (2001) 1.08
Telomerase in T lymphocytes: use it and lose it? J Immunol (2007) 1.05
Association between telomere length and heart disease in a narrow age cohort of older people. Exp Gerontol (2006) 1.05
Beneficial effects of individualized physical activity on prescription on body composition and cardiometabolic risk factors: results from a randomized controlled trial. Eur J Cardiovasc Prev Rehabil (2009) 1.02
Telomere length is a biomarker of cumulative oxidative stress, biologic age, and an independent predictor of survival and therapeutic treatment requirement associated with smoking behavior. Am J Ther (2011) 1.02
Reduced telomere length variation in healthy oldest old. Mech Ageing Dev (2008) 0.97
The pattern of chromosome-specific variations in telomere length in humans shows signs of heritability and is maintained through life. Ann N Y Acad Sci (2006) 0.95
Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress--implications for tissue and organismal aging. Mech Ageing Dev (2011) 0.95
Population mixture model for nonlinear telomere dynamics. Phys Rev E Stat Nonlin Soft Matter Phys (2008) 0.78
Ultraviolet radiation exposure and risk of malignant lymphomas. J Natl Cancer Inst (2005) 3.19
Somatically mutated Ig V(H)3-21 genes characterize a new subset of chronic lymphocytic leukemia. Blood (2002) 3.00
Shortened telomere length is associated with increased risk of cancer: a meta-analysis. PLoS One (2011) 2.61
Breast cancer survival is associated with telomere length in peripheral blood cells. Cancer Res (2008) 2.24
The individual blood cell telomere attrition rate is telomere length dependent. PLoS Genet (2009) 2.17
Telomere length and heredity: Indications of paternal inheritance. Proc Natl Acad Sci U S A (2005) 2.10
Plasma bilirubin and UGT1A1*28 are not protective factors against first-time myocardial infarction in a prospective, nested case-referent setting. Circ Cardiovasc Genet (2010) 2.06
Polymorphism in the P2X7 receptor gene and survival in chronic lymphocytic leukaemia. Lancet (2002) 1.97
Telomere length is associated with obesity parameters but with a gender difference. Obesity (Silver Spring) (2008) 1.87
Subsets with restricted immunoglobulin gene rearrangement features indicate a role for antigen selection in the development of chronic lymphocytic leukemia. Blood (2004) 1.77
Differential expression of p63 isoforms in normal tissues and neoplastic cells. J Pathol (2002) 1.67
Measures of oxidized low-density lipoprotein and oxidative stress are not related and not elevated in otherwise healthy men with the metabolic syndrome. Arterioscler Thromb Vasc Biol (2005) 1.53
Associations between estimated fatty acid desaturase activities in serum lipids and adipose tissue in humans: links to obesity and insulin resistance. Lipids Health Dis (2009) 1.48
Stand up for health--avoiding sedentary behaviour might lengthen your telomeres: secondary outcomes from a physical activity RCT in older people. Br J Sports Med (2014) 1.45
ERK phosphorylation is linked to VEGFR2 expression and Ets-2 phosphorylation in breast cancer and is associated with tamoxifen treatment resistance and small tumours with good prognosis. Oncogene (2005) 1.42
Seven modifiable lifestyle factors predict reduced risk for ischemic cardiovascular disease and all-cause mortality regardless of body mass index: a cohort study. Int J Cardiol (2012) 1.35
The cyclin D1 high and cyclin E high subgroups of breast cancer: separate pathways in tumorogenesis based on pattern of genetic aberrations and inactivation of the pRb node. Oncogene (2002) 1.33
Large-scale parent-child comparison confirms a strong paternal influence on telomere length. Eur J Hum Genet (2009) 1.33
Short telomeres in depression and the general population are associated with a hypocortisolemic state. Biol Psychiatry (2011) 1.31
Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis. Mod Pathol (2005) 1.31
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17. PLoS Genet (2006) 1.29
Family history of hematopoietic malignancy and risk of lymphoma. J Natl Cancer Inst (2005) 1.29
Characterization of the expression of the ALK receptor tyrosine kinase in mice. Gene Expr Patterns (2006) 1.24
Telomere length as a prognostic parameter in chronic lymphocytic leukemia with special reference to VH gene mutation status. Blood (2005) 1.22
hTERT cancer risk genotypes are associated with telomere length. Genet Epidemiol (2012) 1.20
Telomere length as a biological marker in malignancy. Biochim Biophys Acta (2009) 1.19
Telomere length in peripheral blood predicts survival in clear cell renal cell carcinoma. Cancer Res (2009) 1.18
Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential mechanism. J Autoimmun (2009) 1.13
hTERT (-1327)T/C polymorphism is not associated with age-related telomere attrition in peripheral blood. Biochem Biophys Res Commun (2007) 1.12
Variation in DNA repair genes ERCC2, XRCC1, and XRCC3 and risk of follicular lymphoma. Cancer Epidemiol Biomarkers Prev (2006) 1.03
Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity. PLoS One (2012) 1.02
Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma. Blood (2003) 1.00
Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis. Eur J Cancer (2009) 1.00
Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization. Mod Pathol (2002) 0.99
Borrelia infection and risk of non-Hodgkin lymphoma. Blood (2008) 0.98
Genotoxic effects of particles of surgical cobalt chrome alloy on human cells of different age in vitro. Mutat Res (2007) 0.98
Short telomere length is associated with NOTCH1/SF3B1/TP53 aberrations and poor outcome in newly diagnosed chronic lymphocytic leukemia patients. Am J Hematol (2013) 0.97
MNS16A minisatellite genotypes in relation to risk of glioma and meningioma and to glioblastoma outcome. Int J Cancer (2009) 0.97
The PTEN regulator DJ-1 is associated with hTERT expression in clear cell renal cell carcinoma. Int J Cancer (2009) 0.96
Immortalization of bovine capillary endothelial cells by hTERT alone involves inactivation of endogenous p16INK4A/pRb. FASEB J (2003) 0.95
Functional effector memory T cells enrich the peritoneal cavity of patients treated with peritoneal dialysis. J Am Soc Nephrol (2009) 0.94
Complex p63 mRNA isoform expression patterns in squamous cell carcinoma of the head and neck. Int J Oncol (2004) 0.93
Somatic hypermutation and V(H) gene usage in mantle cell lymphoma. Eur J Haematol (2002) 0.93
Lipoprotein lipase is differentially expressed in prognostic subsets of chronic lymphocytic leukemia but displays invariably low catalytical activity. Leuk Res (2009) 0.92
Quantitative evaluation of p16(INK4a) promoter methylation using pyrosequencing in de novo diffuse large B-cell lymphoma. Leuk Res (2010) 0.92
Promoter DNA methylation pattern identifies prognostic subgroups in childhood T-cell acute lymphoblastic leukemia. PLoS One (2013) 0.91
Milk-derived fatty acids are associated with a more favorable LDL particle size distribution in healthy men. J Nutr (2004) 0.91
APOE ε4 is associated with longer telomeres, and longer telomeres among ε4 carriers predicts worse episodic memory. Neurobiol Aging (2010) 0.90
Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck. Adv Otorhinolaryngol (2005) 0.90
The interleukin-10 gene promoter polymorphism (-1082) does not correlate with clinical outcome in diffuse large B-cell lymphoma. Blood (2005) 0.89
A quality assessment survey of SNP genotyping laboratories. Hum Mutat (2006) 0.89
Minimal residual disease quantification in childhood acute lymphoblastic leukemia by real-time polymerase chain reaction using the SYBR green dye. Exp Hematol (2002) 0.89
TP53 mutations predict for poor survival in de novo diffuse large B-cell lymphoma of germinal center subtype. Leuk Res (2008) 0.88
Mast cell infiltration is a favourable prognostic factor in diffuse large B-cell lymphoma. Br J Haematol (2007) 0.88
Cyclin E and p27 protein content in human renal cell carcinoma: clinical outcome and associations with cyclin D. Int J Cancer (2002) 0.87
Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures. Aging Cell (2010) 0.87
Cyclin D3 protein content in human renal cell carcinoma in relation to cyclin D1 and clinico-pathological parameters. Acta Oncol (2002) 0.87
Longer leukocyte telomere length is associated with smaller hippocampal volume among non-demented APOE ε3/ε3 subjects. PLoS One (2012) 0.86
TERT promoter mutations in clear cell renal cell carcinoma. Int J Cancer (2014) 0.84
Shorter telomere length is linked to brain atrophy and white matter hyperintensities. Age Ageing (2013) 0.84
Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks. Biochim Biophys Acta (2012) 0.83
Cigarette smoking and risk of non-Hodgkin's lymphoma--a population-based case-control study. Cancer Epidemiol Biomarkers Prev (2005) 0.83
Lymphoplasmacytic lymphoma/Waldenström's macroglobulinemia derives from an extensively hypermutated B cell that lacks ongoing somatic hypermutation. Leuk Res (2005) 0.83
Long leukocyte telomere length in prostate cancer patients at diagnosis is associated with poor metastasis-free and cancer-specific survival. Tumour Biol (2017) 0.82
The GNAS1 T393C polymorphism and lack of clinical prognostic value in chronic lymphocytic leukemia. Leuk Res (2007) 0.82
Detection of antibodies against p63 and p73 isoforms in sera from patients diagnosed with oral lichen planus. J Oral Pathol Med (2007) 0.82
Financial stress in late adulthood and diverse risks of incident cardiovascular disease and all-cause mortality in women and men. BMC Public Health (2014) 0.82
Telomere maintenance and cell cycle regulation in spontaneously immortalized T-cell lines from Nijmegen breakage syndrome patients. Exp Cell Res (2003) 0.82
Genes associated with the tumour microenvironment are differentially expressed in cured versus primary chemotherapy-refractory diffuse large B-cell lymphoma. Br J Haematol (2008) 0.82
A mutation in the H/ACA box of telomerase RNA component gene (TERC) in a young patient with myelodysplastic syndrome. BMC Med Genet (2014) 0.81
Genomic imbalances during transformation from follicular lymphoma to diffuse large B-cell lymphoma. Mod Pathol (2006) 0.81
BCL2 expression in de novo diffuse large B-cell lymphoma partly reflects normal differences in age distribution. Br J Haematol (2009) 0.81
Retinoblastoma protein in human renal cell carcinoma in relation to alterations in G1/S regulatory proteins. Int J Cancer (2004) 0.81
Low levels of IgM antibodies to oxidized cardiolipin increase and high levels decrease risk of cardiovascular disease among 60-year olds: a prospective study. BMC Cardiovasc Disord (2013) 0.80
VH gene mutation status and cellular drug resistance in chronic lymphocytic leukaemia. Eur J Haematol (2004) 0.80
Reproducibility of Telomere Length Assessment - An International Collaborative Study. Int J Epidemiol (2015) 0.80
Vascular density in childhood acute lymphoblastic leukaemia correlates to biological factors and outcome. Br J Haematol (2009) 0.80
Telomere length in relation to immunological parameters in patients with renal cell carcinoma. PLoS One (2013) 0.80
Patients with chronic lymphocytic leukemia with mutated VH genes presenting with Binet stage B or C form a subgroup with a poor outcome. Haematologica (2005) 0.80
hTERT gene copy number is not associated with hTERT RNA expression or telomerase activity in colorectal cancer. Int J Cancer (2005) 0.79
hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup. Exp Hematol (2011) 0.79
CD40 expression identifies a prognostically favourable subgroup of diffuse large B-cell lymphoma. Leuk Lymphoma (2007) 0.79
Spontaneously immortalized human T lymphocytes develop gain of chromosomal region 2p13-24 as an early and common genetic event. Genes Chromosomes Cancer (2004) 0.79
Clonally related splenic marginal zone lymphoma and Hodgkin lymphoma with unmutated V gene rearrangements and a 15-yr time gap between diagnoses. Eur J Haematol (2004) 0.78
Telomere length and correlation with histopathogenesis in B-cell leukemias/lymphomas. Eur J Haematol (2007) 0.77