PubRank

Thomas Gridley

Author PubWeight™ 99.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev 2004 3.95
2 Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007 3.19
3 Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. Genes Dev 2004 3.00
4 Developmental transcription factor slug is required for effective re-epithelialization by adult keratinocytes. J Cell Physiol 2005 2.91
5 A mouse model of Alagille syndrome: Notch2 as a genetic modifier of Jag1 haploinsufficiency. Development 2002 2.88
6 gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell 2004 2.68
7 Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proc Natl Acad Sci U S A 2009 2.63
8 The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet 2006 2.56
9 The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear. Development 2005 2.36
10 Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron 2008 2.31
11 A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood 2004 2.06
12 Critical role of endothelial Notch1 signaling in postnatal angiogenesis. Circ Res 2006 1.91
13 Characterization of Notch3-deficient mice: normal embryonic development and absence of genetic interactions with a Notch1 mutation. Genesis 2003 1.84
14 Brain lipid-binding protein is a direct target of Notch signaling in radial glial cells. Genes Dev 2005 1.81
15 Bile duct proliferation in liver-specific Jag1 conditional knockout mice: effects of gene dosage. Hepatology 2007 1.78
16 Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. Genes Dev 2003 1.76
17 Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J 2008 1.71
18 Repression of PTEN phosphatase by Snail1 transcriptional factor during gamma radiation-induced apoptosis. Mol Cell Biol 2008 1.68
19 Loss of notch activity in the developing central nervous system leads to increased cell death. Dev Neurosci 2006 1.65
20 Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Blood 2010 1.60
21 Notch signaling regulates bile duct morphogenesis in mice. PLoS One 2008 1.59
22 Snail family genes are required for left-right asymmetry determination, but not neural crest formation, in mice. Proc Natl Acad Sci U S A 2006 1.58
23 Smooth muscle Notch1 mediates neointimal formation after vascular injury. Circulation 2009 1.58
24 Generation of new Notch2 mutant alleles. Genesis 2006 1.56
25 Slug is a novel downstream target of MyoD. Temporal profiling in muscle regeneration. J Biol Chem 2002 1.50
26 Multiple functions of Snail family genes during palate development in mice. Development 2007 1.45
27 Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. Dev Dyn 2006 1.37
28 Notch2 governs the rate of generation of mouse long- and short-term repopulating stem cells. J Clin Invest 2011 1.29
29 Blockade of individual Notch ligands and receptors controls graft-versus-host disease. J Clin Invest 2013 1.27
30 TCF and Groucho-related genes influence pituitary growth and development. Mol Endocrinol 2003 1.24
31 Notch1 activation in mice causes arteriovenous malformations phenocopied by ephrinB2 and EphB4 mutants. Genesis 2010 1.20
32 The developmental transcription factor slug is widely expressed in tissues of adult mice. J Histochem Cytochem 2004 1.20
33 Cell movements during gastrulation: snail dependent and independent pathways. Curr Opin Genet Dev 2002 1.16
34 Generation of a Snail1 (Snai1) conditional null allele. Genesis 2006 1.14
35 Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice. Genesis 2002 1.14
36 Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol 2009 1.12
37 Patent ductus arteriosus in mice with smooth muscle-specific Jag1 deletion. Development 2010 1.10
38 Craniosynostosis in Twist heterozygous mice: a model for Saethre-Chotzen syndrome. Anat Rec 2002 1.09
39 Role of the Notch signalling pathway in tooth morphogenesis. Arch Oral Biol 2004 1.08
40 Conditional deletion of Notch1 and Notch2 genes in excitatory neurons of postnatal forebrain does not cause neurodegeneration or reduction of Notch mRNAs and proteins. J Biol Chem 2012 1.07
41 Molecular pathways of notch signaling in vascular smooth muscle cells. Front Physiol 2012 1.07
42 Notch signaling coordinates the patterning of striatal compartments. Development 2005 1.05
43 The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo. Hum Mol Genet 2007 1.04
44 Snail regulates p21(WAF/CIP1) expression in cooperation with E2A and Twist. Biochem Biophys Res Commun 2004 1.02
45 Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength. J Exp Med 2013 1.00
46 Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development. Dev Biol 2011 0.99
47 Notch controls the magnitude of T helper cell responses by promoting cellular longevity. Proc Natl Acad Sci U S A 2012 0.99
48 Laser surgery for mouse geneticists. Nat Biotechnol 2007 0.97
49 Mutation of a ubiquitously expressed mouse transmembrane protein (Tapt1) causes specific skeletal homeotic transformations. Genetics 2006 0.95
50 Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium. Dev Biol 2007 0.95
51 Epiblast-specific Snai1 deletion results in embryonic lethality due to multiple vascular defects. BMC Res Notes 2009 0.95
52 Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res 2013 0.95
53 BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation. Development 2010 0.92
54 Slug expression during organogenesis in mice. Anat Rec A Discov Mol Cell Evol Biol 2003 0.92
55 Snail1 gene function during early embryo patterning in mice. Cell Cycle 2006 0.92
56 Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles. BMC Biol 2013 0.91
57 Notch1 expression and ligand interactions in progenitor cells of the mouse olfactory epithelium. J Mol Histol 2007 0.90
58 Generation of mice with a conditional null allele of the Jagged2 gene. Genesis 2010 0.89
59 Mutations in snail family genes enhance craniosynostosis of Twist1 haplo-insufficient mice: implications for Saethre-Chotzen Syndrome. Genetics 2005 0.88
60 The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis. Biochem Biophys Res Commun 2013 0.87
61 Genetic background modifies inner ear and eye phenotypes of jag1 heterozygous mice. Genetics 2007 0.86
62 Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth. Dev Biol 2002 0.86
63 Growth defect in Grg5 null mice is associated with reduced Ihh signaling in growth plates. Dev Dyn 2002 0.86
64 Notch Signaling during Oogenesis in Drosophila melanogaster. Genet Res Int 2012 0.85
65 Mesenchymal cell remodeling during mouse secondary palate reorientation. Dev Dyn 2010 0.85
66 The snail family gene snai3 is not essential for embryogenesis in mice. PLoS One 2013 0.83
67 Vascular biology: vessel guidance. Nature 2007 0.83
68 Jagged1-mediated Notch signaling regulates mammalian inner ear development independent of lateral inhibition. Acta Otolaryngol 2012 0.81
69 The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice. Genesis 2012 0.79
70 Absence of a major role for the snai1 and snai3 genes in regulating skeletal muscle regeneration in mice. PLoS Curr 2013 0.75
71 Not all lunatic fringe null female mice are infertile. Development 2006 0.75