Published in Br J Psychiatry on April 01, 2011
Power and predictive accuracy of polygenic risk scores. PLoS Genet (2013) 3.72
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study. Lancet (2015) 2.74
Shared polygenic contribution between childhood attention-deficit hyperactivity disorder and adult schizophrenia. Br J Psychiatry (2013) 1.70
Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia. Mol Psychiatry (2013) 1.39
Genetic risk for attention-deficit/hyperactivity disorder contributes to neurodevelopmental traits in the general population. Biol Psychiatry (2014) 1.38
High loading of polygenic risk for ADHD in children with comorbid aggression. Am J Psychiatry (2013) 1.10
Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder. Schizophr Bull (2014) 1.01
Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis. PLoS One (2012) 0.95
Genome-wide association of mood-incongruent psychotic bipolar disorder. Transl Psychiatry (2012) 0.92
CACNA1C risk variant and amygdala activity in bipolar disorder, schizophrenia and healthy controls. PLoS One (2013) 0.92
Prefrontal inefficiency is associated with polygenic risk for schizophrenia. Schizophr Bull (2013) 0.89
How does a Developmental Perspective inform us about the early Natural History of Bipolar Disorder? J Can Acad Child Adolesc Psychiatry (2013) 0.88
Polygenic Epidemiology. Genet Epidemiol (2016) 0.83
Assessment of first and second degree relatives of individuals with bipolar disorder shows increased genetic risk scores in both affected relatives and young At-Risk Individuals. Am J Med Genet B Neuropsychiatr Genet (2015) 0.77
Molecular genetics of the psychosis phenotype. Can J Psychiatry (2012) 0.75
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Population structure and eigenanalysis. PLoS Genet (2006) 37.21
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Research diagnostic criteria: rationale and reliability. Arch Gen Psychiatry (1978) 15.32
Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. Lancet (2009) 12.96
A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry (1978) 12.65
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Arch Gen Psychiatry (1991) 6.74
Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry (2009) 4.74
A twin study of genetic relationships between psychotic symptoms. Am J Psychiatry (2002) 3.95
The structure of psychosis: latent class analysis of probands from the Roscommon Family Study. Arch Gen Psychiatry (1998) 3.61
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry (2009) 3.59
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry (2008) 3.01
Rethinking psychosis: the disadvantages of a dichotomous classification now outweigh the advantages. World Psychiatry (2007) 2.82
Dissecting the phenotype in genome-wide association studies of psychiatric illness. Br J Psychiatry (2009) 2.65
Concurrent validity of the OPCRIT diagnostic system. Comparison of OPCRIT diagnoses with consensus best-estimate lifetime diagnoses. Br J Psychiatry (1996) 2.42
Psychosis genetics: modeling the relationship between schizophrenia, bipolar disorder, and mixed (or "schizoaffective") psychoses. Schizophr Bull (2009) 2.39
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype. Mol Psychiatry (2008) 2.38
A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res (2004) 2.24
The continuum of psychosis and its genetic origins. The sixty-fifth Maudsley lecture. Br J Psychiatry (1990) 2.23
Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry (2010) 2.21
Are schizophrenia and affective disorder related? A selective literature review. Am J Psychiatry (1992) 1.73
Severe mental disorders in offspring with 2 psychiatrically ill parents. Arch Gen Psychiatry (2010) 1.66
Diagnosis and classification of functional psychoses. Br Med Bull (1987) 1.58
A comparison of the utility of dimensional and categorical representations of psychosis. UK700 Group. Psychol Med (1999) 1.47
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept. Br J Psychiatry (2009) 1.45
The Bipolar Affective Disorder Dimension Scale (BADDS)--a dimensional scale for rating lifetime psychopathology in bipolar spectrum disorders. BMC Psychiatry (2004) 1.38
The identification of disease entities and the relationship between schizophrenic and affective psychoses. Br J Psychiatry (1980) 1.37
The distinction between the affective psychoses and schizophrenia. Br J Psychiatry (1979) 1.00
Bipolar disorder and schizophrenia: not so distant relatives? World Psychiatry (2003) 0.98
The nosology of schizoaffective psychosis. Psychiatr Dev (1983) 0.92
Classification of schizo-affective patients by multidimensional scaling and cluster analysis. Psychiatr Clin (Basel) (1983) 0.90
Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype. Mol Psychiatry (2010) 0.89
The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature (1997) 33.47
Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nat Genet (1999) 24.24
The genome sequence of Schizosaccharomyces pombe. Nature (2002) 14.26
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell (1997) 13.53
The Composite International Diagnostic Interview. An epidemiologic Instrument suitable for use in conjunction with different diagnostic systems and in different cultures. Arch Gen Psychiatry (1988) 12.83
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Mutations involving the transcription factor CBFA1 cause cleidocranial dysplasia. Cell (1997) 7.47
Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study). Lancet (2004) 7.33
Whole-genome association study of bipolar disorder. Mol Psychiatry (2008) 6.80
QTc-interval abnormalities and psychotropic drug therapy in psychiatric patients. Lancet (2000) 6.78
A polydiagnostic application of operational criteria in studies of psychotic illness. Development and reliability of the OPCRIT system. Arch Gen Psychiatry (1991) 6.74
The Genome Sequence DataBase: towards an integrated functional genomics resource. Nucleic Acids Res (1999) 6.20
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83
High rates of schizophrenia in adults with velo-cardio-facial syndrome. Arch Gen Psychiatry (1999) 5.54
A prospective study of acute cerebrovascular disease in the community: the Oxfordshire Community Stroke Project 1981-86. 1. Methodology, demography and incident cases of first-ever stroke. J Neurol Neurosurg Psychiatry (1988) 4.98
De novo CNV analysis implicates specific abnormalities of postsynaptic signalling complexes in the pathogenesis of schizophrenia. Mol Psychiatry (2011) 4.91
Regional variations in the use of common surgical procedures: within and between England and Wales, Canada and the United States of America. Soc Sci Med A (1981) 4.88
Fetal fibronectin in cervical and vaginal secretions as a predictor of preterm delivery. N Engl J Med (1991) 4.68
Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nat Genet (2000) 4.66
The strength of the genetic effect. Is there room for an environmental influence in the aetiology of schizophrenia? Br J Psychiatry (1994) 4.40
Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation. Cell (1994) 4.07
Primary structure of human transferrin receptor deduced from the mRNA sequence. Nature (1984) 4.04
Screening could seriously damage your health. BMJ (1997) 4.04
The genetics of schizophrenia and bipolar disorder: dissecting psychosis. J Med Genet (2005) 4.02
Use of computerised general practice data for population surveillance: comparative study of influenza data. BMJ (1991) 3.99
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
Health checks in general practice: another example of inverse care? BMJ (1990) 3.83
Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus. Brain-derived neutrophic factor. Mol Psychiatry (2002) 3.78
Lithium neurotoxicity at normal therapeutic levels. Br J Psychiatry (1993) 3.76
Genomewide genetic linkage analysis confirms the presence of susceptibility loci for schizophrenia, on chromosomes 1q32.2, 5q33.2, and 8p21-22 and provides support for linkage to schizophrenia, on chromosomes 11q23.3-24 and 20q12.1-11.23. Am J Hum Genet (2001) 3.73
Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. Am J Hum Genet (2000) 3.69
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry (2009) 3.59
Gene-environment interaction analysis of serotonin system markers with adolescent depression. Mol Psychiatry (2004) 3.54
LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Mol Psychiatry (2007) 3.49
A total audit of preventive procedures in 45 practices caring for 430,000 patients. BMJ (1990) 3.45
The broad clinical spectrum of bipolar disorder: implications for research and practice. J Psychopharmacol (2008) 3.45
Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature (1988) 3.44
Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev (2001) 3.43
ISYS: a decentralized, component-based approach to the integration of heterogeneous bioinformatics resources. Bioinformatics (2001) 3.36
The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis. Mol Psychiatry (2007) 3.34
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet (1999) 3.25
The bipolar-borderline personality disorders connection in major depressive patients. Acta Psychiatr Scand (2013) 3.12
Lack of willpower or lack of wherewithal? "Internal" and "external" barriers to changing diet and exercise in a three year follow-up of participants in a health check. Soc Sci Med (1998) 3.10
Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch Gen Psychiatry (1999) 3.07
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol Psychiatry (2008) 3.01
New evidence on the state of stress of the san andreas fault system. Science (1987) 2.97
Protection against Alzheimer's disease with apoE epsilon 2. Lancet (1994) 2.96
Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned. Mol Psychiatry (2010) 2.95
Biosynthesis of HLA-A and HLA-B antigens in vivo. J Biol Chem (1980) 2.94
Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells. Science (1992) 2.90
SNP association studies in Alzheimer's disease highlight problems for complex disease analysis. Trends Genet (2001) 2.86
The moderation by the serotonin transporter gene of environmental adversity in the etiology of depression: 2009 update. Mol Psychiatry (2010) 2.82
Medical complications after stroke: a multicenter study. Stroke (2000) 2.81
Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature (1990) 2.80
The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. Mol Psychiatry (2006) 2.80
Analysis of the neuroligin 3 and 4 genes in autism and other neuropsychiatric patients. Mol Psychiatry (2005) 2.78
Molecular cloning of the human T-lymphocyte surface CD2 (T11) antigen. Proc Natl Acad Sci U S A (1986) 2.76
T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment. Am J Pathol (1997) 2.76
Thioridazine and sudden unexplained death in psychiatric in-patients. Br J Psychiatry (2002) 2.69
A comparison of clinical and diagnostic interview schedule diagnoses. Physician reexamination of lay-interviewed cases in the general population. Arch Gen Psychiatry (1985) 2.66
Short acting benzodiazepines. BMJ (1993) 2.66
Drug treatment for benign prostatic hyperplasia. BMJ (1997) 2.65
The genetic basis of complex human behaviors. Science (1994) 2.62
Seismicity remotely triggered by the magnitude 7.3 landers, california, earthquake. Science (1993) 2.61
A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role in susceptibility to affective disorders. Mol Psychiatry (1996) 2.60
Costs and cost effectiveness of health checks conducted by nurses in primary care: the Oxcheck study. BMJ (1996) 2.58
Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice. J Exp Med (1999) 2.58
Spontaneous thyroiditis in thymectomized and irradiated Wistar rats. Clin Exp Immunol (1973) 2.55
Susceptibility locus for Alzheimer's disease on chromosome 10. Science (2000) 2.49
Setting up consensus standards for the care of patients in general practice. Br J Gen Pract (1991) 2.49
Structural brain abnormalities associated with deletion at chromosome 22q11: quantitative neuroimaging study of adults with velo-cardio-facial syndrome. Br J Psychiatry (2001) 2.49
Productive T-cell receptor beta-chain gene rearrangement: coincident regulation of cell cycle and clonality during development in vivo. Genes Dev (1996) 2.47
Serotonin reuptake inhibitor discontinuation syndrome: a hypothetical definition. Discontinuation Consensus panel. J Clin Psychiatry (1997) 2.46