Role of molecular imaging in stem cell therapy for myocardial restoration.

PubWeight™: 0.80‹?›

🔗 View Article (PMC 3625429)

Published in Trends Cardiovasc Med on August 01, 2010

Authors

Maarten A Lijkwan1, Ernst Jan Bos, Joseph C Wu, Robert C Robbins

Author Affiliations

1: Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

Articles cited by this

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51

Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50

Bone marrow cells regenerate infarcted myocardium. Nature (2001) 21.24

Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med (2001) 18.91

Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation (2008) 15.35

Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet (2004) 9.35

Functional cardiomyocytes derived from human induced pluripotent stem cells. Circ Res (2009) 7.09

Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI). Circulation (2002) 6.50

Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial. Eur Heart J (2006) 4.69

Monitoring of bone marrow cell homing into the infarcted human myocardium. Circulation (2005) 4.20

In vivo magnetic resonance imaging of mesenchymal stem cells in myocardial infarction. Circulation (2003) 4.00

Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation (2005) 3.33

The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation. Circulation (2008) 3.30

Human pharmacokinetic and dosimetry studies of [(18)F]FHBG: a reporter probe for imaging herpes simplex virus type-1 thymidine kinase reporter gene expression. J Nucl Med (2001) 3.03

Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation (2009) 2.93

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85

A new transgene reporter for in vivo magnetic resonance imaging. Nat Med (2005) 2.85

Emission spectra of bioluminescent reporters and interaction with mammalian tissue determine the sensitivity of detection in vivo. J Biomed Opt (2005) 2.69

Red-shifted Renilla reniformis luciferase variants for imaging in living subjects. Nat Methods (2007) 2.64

Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation (2003) 2.63

Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma. Nat Clin Pract Oncol (2008) 2.61

Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol (2009) 2.58

Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation (2003) 2.37

Genotoxicity of retroviral integration in hematopoietic cells. Mol Ther (2006) 2.34

Effects of cell number on teratoma formation by human embryonic stem cells. Cell Cycle (2009) 2.30

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. Proc Natl Acad Sci U S A (2008) 2.25

Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation (2008) 2.22

Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer. Proc Natl Acad Sci U S A (2008) 2.20

Skeletal myoblast transplantation for repair of myocardial necrosis. J Clin Invest (1996) 2.20

Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol (2008) 2.16

Imaging transgene expression with radionuclide imaging technologies. Neoplasia (2000) 2.03

Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93

Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Stem Cells (2008) 1.90

Stem and progenitor cells: the premature desertion of rigorous definitions. Trends Neurosci (2003) 1.86

Construction and validation of improved triple fusion reporter gene vectors for molecular imaging of living subjects. Cancer Res (2007) 1.74

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation (2009) 1.73

Monitoring cell therapy using iron oxide MR contrast agents. Curr Pharm Biotechnol (2004) 1.71

Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. Stem Cells Dev (2007) 1.65

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning Stem Cells (2007) 1.62

Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev (2008) 1.46

In vitro model of bromodeoxyuridine or iron oxide nanoparticle uptake by activated macrophages from labeled stem cells: implications for cellular therapy. Stem Cells (2008) 1.41

Imaging stem cells implanted in infarcted myocardium. J Am Coll Cardiol (2006) 1.28

Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation. Physiol Genomics (2006) 1.26

Gadolinium-fullerenol as a paramagnetic contrast agent for cellular imaging. Invest Radiol (2006) 1.24

Proteomic analysis of reporter genes for molecular imaging of transplanted embryonic stem cells. Proteomics (2006) 1.24

A tracer kinetic model for 18F-FHBG for quantitating herpes simplex virus type 1 thymidine kinase reporter gene expression in living animals using PET. J Nucl Med (2004) 1.19

In vivo imaging and quantitation of adoptively transferred human antigen-specific T cells transduced to express a human norepinephrine transporter gene. Cancer Res (2007) 1.15

In Vivo Cellular Imaging for Translational Medical Research. Curr Med Imaging Rev (2009) 1.12

Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trial. Eur J Heart Fail (2009) 1.05

Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models. Cell Res (2009) 1.02

Current perspectives on imaging cardiac stem cell therapy. J Nucl Med (2010) 1.00

Cell-based therapy for ischemic heart disease: a clinical update. Ann Thorac Surg (2009) 1.00

Stem cell therapy in acute myocardial infarction: a review of clinical trials. Transl Res (2010) 1.00

Stem cells in the treatment of heart disease. Annu Rev Med (2010) 1.00

ES and iPS cell research for cardiovascular regeneration. Exp Cell Res (2010) 0.98

Molecular imaging of endothelial progenitor cell engraftment using contrast-enhanced ultrasound and targeted microbubbles. Cardiovasc Res (2009) 0.98

Evaluation of the specificity and sensitivity of ferritin as an MRI reporter gene in the mouse brain using lentiviral and adeno-associated viral vectors. Gene Ther (2011) 0.98

Embryonic and adult stem cell therapy. J Allergy Clin Immunol (2010) 0.97

Imaging approaches for the study of cell-based cardiac therapies. Nat Rev Cardiol (2009) 0.96

Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. J Thorac Cardiovasc Surg (2008) 0.94

Transcriptional profiling of human mesenchymal stem cells transduced with reporter genes for imaging. Physiol Genomics (2008) 0.93

Molecular imaging of human embryonic stem cells. Methods Mol Biol (2009) 0.90

Imaging stem cell implant for cellular-based therapies. Exp Biol Med (Maywood) (2008) 0.87

Tracking stem cell therapy in the myocardium: applications of positron emission tomography. Curr Pharm Des (2008) 0.86

Seeing is believing: tracking cells to determine the effects of cell transplantation. Semin Thorac Cardiovasc Surg (2008) 0.79

Articles by these authors

Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature (2004) 8.36

In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48

A nonviral minicircle vector for deriving human iPS cells. Nat Methods (2010) 4.42

Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming. Cell Stem Cell (2012) 3.66

Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells. Proc Natl Acad Sci U S A (2009) 3.57

Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med (2012) 3.53

Human tissue-engineered blood vessels for adult arterial revascularization. Nat Med (2006) 3.39

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol (2011) 3.05

Transplantation for idiopathic pulmonary arterial hypertension: improvement in the lung allocation score era. Circulation (2013) 2.87

Persistent donor cell gene expression among human induced pluripotent stem cells contributes to differences with human embryonic stem cells. PLoS One (2010) 2.86

Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS One (2008) 2.85

Single cell transcriptional profiling reveals heterogeneity of human induced pluripotent stem cells. J Clin Invest (2011) 2.69

Imaging survival and function of transplanted cardiac resident stem cells. J Am Coll Cardiol (2009) 2.58

Drug screening using a library of human induced pluripotent stem cell-derived cardiomyocytes reveals disease-specific patterns of cardiotoxicity. Circulation (2013) 2.57

MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells Dev (2009) 2.44

Short-term immunosuppression promotes engraftment of embryonic and induced pluripotent stem cells. Cell Stem Cell (2011) 2.35

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell (2013) 2.33

MicroRNA-210 as a novel therapy for treatment of ischemic heart disease. Circulation (2010) 2.32

Effects of cell number on teratoma formation by human embryonic stem cells. Cell Cycle (2009) 2.30

Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts. Proc Natl Acad Sci U S A (2008) 2.25

Dynamic microRNA expression programs during cardiac differentiation of human embryonic stem cells: role for miR-499. Circ Cardiovasc Genet (2010) 2.24

Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation (2008) 2.22

Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation (2007) 2.21

Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair. J Am Coll Cardiol (2012) 2.18

Consensus conference report: maximizing use of organs recovered from the cadaver donor: cardiac recommendations, March 28-29, 2001, Crystal City, Va. Circulation (2002) 2.14

Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation (2005) 2.12

Patient-specific stem cells and cardiovascular drug discovery. JAMA (2013) 2.06

Dissecting the molecular relationship among various cardiogenic progenitor cells. Circ Res (2013) 2.06

Effects of intracoronary CD34+ stem cell transplantation in nonischemic dilated cardiomyopathy patients: 5-year follow-up. Circ Res (2012) 2.02

Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93

Comparison of reporter gene and iron particle labeling for tracking fate of human embryonic stem cells and differentiated endothelial cells in living subjects. Stem Cells (2008) 1.90

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Circ Res (2012) 1.84

Multimodality cardiovascular molecular imaging, Part II. Circ Cardiovasc Imaging (2009) 1.82

Molecular imaging using labeled donor tissues reveals patterns of engraftment, rejection, and survival in transplantation. Transplantation (2005) 1.82

In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium. Arterioscler Thromb Vasc Biol (2011) 1.80

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. Hum Mol Genet (2010) 1.79

Quantum dot imaging for embryonic stem cells. BMC Biotechnol (2007) 1.78

Pharmacological inhibition of epsilon PKC suppresses chronic inflammation in murine cardiac transplantation model. J Mol Cell Cardiol (2007) 1.78

Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Circulation (2006) 1.75

Microfluidic single-cell analysis shows that porcine induced pluripotent stem cell-derived endothelial cells improve myocardial function by paracrine activation. Circ Res (2012) 1.74

Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation (2009) 1.73

Novel index for invasively assessing the coronary microcirculation. Circulation (2003) 1.69

Absent secretion to vasoactive intestinal peptide in cystic fibrosis airway glands. J Biol Chem (2002) 1.66

Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. Stem Cells Dev (2007) 1.65

Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. PLoS One (2009) 1.64

Molecular imaging of embryonic stem cell misbehavior and suicide gene ablation. Cloning Stem Cells (2007) 1.62

Comparing on-pump and off-pump coronary artery bypass grafting: numerous studies but few conclusions: a scientific statement from the American Heart Association council on cardiovascular surgery and anesthesia in collaboration with the interdisciplinary working group on quality of care and outcomes research. Circulation (2005) 1.61

Novel injectable bioartificial tissue facilitates targeted, less invasive, large-scale tissue restoration on the beating heart after myocardial injury. Circulation (2005) 1.59

Trafficking mesenchymal stem cell engraftment and differentiation in tumor-bearing mice by bioluminescence imaging. Stem Cells (2009) 1.58

Positron emission tomography imaging of conditional gene activation in the heart. J Mol Cell Cardiol (2007) 1.56

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure. Am J Physiol Heart Circ Physiol (2007) 1.54

Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation (2013) 1.54

Hepatocyte growth factor or vascular endothelial growth factor gene transfer maximizes mesenchymal stem cell-based myocardial salvage after acute myocardial infarction. Circulation (2009) 1.54

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns. Nat Protoc (2012) 1.53

Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52

Synergistic airway gland mucus secretion in response to vasoactive intestinal peptide and carbachol is lost in cystic fibrosis. J Clin Invest (2007) 1.50

Molecular imaging of bone marrow mononuclear cell survival and homing in murine peripheral artery disease. JACC Cardiovasc Imaging (2012) 1.49

Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. Circulation (2011) 1.48

A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation. J Exp Med (2013) 1.47

In vivo imaging of embryonic stem cells reveals patterns of survival and immune rejection following transplantation. Stem Cells Dev (2008) 1.46

Novel minicircle vector for gene therapy in murine myocardial infarction. Circulation (2009) 1.45

Human neural stem cell grafts modify microglial response and enhance axonal sprouting in neonatal hypoxic-ischemic brain injury. Stroke (2010) 1.44

Potential role of γδ T cell-derived IL-17 in acute cardiac allograft rejection. Ann Thorac Surg (2012) 1.43

Hyposecretion, not hyperabsorption, is the basic defect of cystic fibrosis airway glands. J Biol Chem (2006) 1.43

Chronotherapeutics (light and wake therapy) in affective disorders. Psychol Med (2005) 1.42

Embryonic stem cell-derived endothelial cells engraft into the ischemic hindlimb and restore perfusion. Arterioscler Thromb Vasc Biol (2010) 1.42

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2. Stem Cells (2013) 1.41

Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology (2009) 1.37

18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. J Nucl Med (2006) 1.37

Effects of adenoviral up-regulation of bcl-2 on oxidative stress and graft coronary artery disease in rat heart transplants. Transplantation (2003) 1.37

Immunogenicity and immunomodulatory properties of umbilical cord lining mesenchymal stem cells. Cell Transplant (2010) 1.36

Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells (2004) 1.35