Published in Mol Cell Biol on December 27, 2011
Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci (2013) 2.01
Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim Biophys Acta (2013) 1.90
The p38/MK2-driven exchange between tristetraprolin and HuR regulates AU-rich element-dependent translation. PLoS Genet (2012) 1.50
Tristetraprolin (TTP) coordinately regulates primary and secondary cellular responses to proinflammatory stimuli. J Leukoc Biol (2015) 1.21
Identification of cytoplasmic capping targets reveals a role for cap homeostasis in translation and mRNA stability. Cell Rep (2012) 1.10
Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction. RNA (2013) 0.90
RNase-L control of cellular mRNAs: roles in biologic functions and mechanisms of substrate targeting. J Interferon Cytokine Res (2014) 0.88
Interleukin-10 inhibits lipopolysaccharide-induced tumor necrosis factor-α translation through a SHIP1-dependent pathway. J Biol Chem (2012) 0.83
Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells. Carcinogenesis (2014) 0.82
Tristetraprolin binding site atlas in the macrophage transcriptome reveals a switch for inflammation resolution. Mol Syst Biol (2016) 0.82
Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs. Mol Cell Biol (2015) 0.82
Role of Rck-Pat1b binding in assembly of processing-bodies. RNA Biol (2013) 0.82
IFNL3 mRNA structure is remodeled by a functional non-coding polymorphism associated with hepatitis C virus clearance. Sci Rep (2015) 0.82
Post-transcriptional regulation of iron homeostasis in Saccharomyces cerevisiae. Int J Mol Sci (2013) 0.80
DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways. Mol Cell (2015) 0.79
Hallmarks of cancer and AU-rich elements. Wiley Interdiscip Rev RNA (2016) 0.78
RNA binding proteins as regulators of immune cell biology. Clin Exp Immunol (2015) 0.77
LPS-induced production of TNF-α and IL-6 in mast cells is dependent on p38 but independent of TTP. Cell Signal (2013) 0.77
Scan for Motifs: a webserver for the analysis of post-transcriptional regulatory elements in the 3' untranslated regions (3' UTRs) of mRNAs. BMC Bioinformatics (2014) 0.76
The DDX6-4E-T interaction mediates translational repression and P-body assembly. Nucleic Acids Res (2016) 0.76
An AU-rich instability element in the 3'UTR mediates an increase in mRNA stability in response to expression of a dhh1 ATPase mutant. Translation (Austin) (2014) 0.75
Post-transcriptional regulation of cytokine and growth factor signaling in cancer. Cytokine Growth Factor Rev (2016) 0.75
Dual mechanisms regulate the nucleocytoplasmic localization of human DDX6. Sci Rep (2017) 0.75
Targeting RNA helicases in cancer: The translation trap. Biochim Biophys Acta (2017) 0.75
Handshakes and Fights: The Regulatory Interplay of RNA-Binding Proteins. Front Mol Biosci (2017) 0.75
Switching from repression to activation: microRNAs can up-regulate translation. Science (2007) 17.00
Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev (2006) 15.20
AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem Sci (1995) 14.81
Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol (2005) 9.25
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin. Science (1998) 8.55
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Cell (2001) 7.79
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity (1999) 7.34
Circularization of mRNA by eukaryotic translation initiation factors. Mol Cell (1998) 6.47
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol (2006) 6.41
General translational repression by activators of mRNA decapping. Cell (2005) 6.40
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J (2002) 6.08
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2. Cell (2007) 5.87
A pathogenetic role for TNF alpha in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency. Immunity (1996) 5.64
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol (2008) 5.57
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA. Mol Cell Biol (1999) 5.55
Control of translation initiation in animals. Annu Rev Cell Dev Biol (1998) 5.09
Mammalian stress granules and processing bodies. Methods Enzymol (2007) 4.76
Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping. Mol Cell (2005) 4.60
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell (2009) 4.57
Recruitment and activation of mRNA decay enzymes by two ARE-mediated decay activation domains in the proteins TTP and BRF-1. Genes Dev (2005) 4.43
TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J (2000) 4.41
Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level. J Exp Med (1990) 4.21
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J (2002) 4.13
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability. Blood (2000) 3.86
Translational blockade imposed by cytokine-derived UA-rich sequences. Science (1989) 3.68
GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation. J Cell Sci (2004) 3.31
Dead-box proteins: a family affair--active and passive players in RNP-remodeling. Nucleic Acids Res (2006) 3.26
TTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elements. Genes Dev (2007) 3.14
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts. Mol Cell Biol (2006) 2.96
CPEB, maskin, and cyclin B1 mRNA at the mitotic apparatus: implications for local translational control of cell division. Cell (2000) 2.66
A conserved role of a DEAD box helicase in mRNA masking. RNA (2001) 2.20
AU-rich element-mediated translational control: complexity and multiple activities of trans-activating factors. Biochem Soc Trans (2002) 2.18
The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR. Mol Cell Biol (2001) 2.09
Translational repression by RNA-binding protein TIAR. Mol Cell Biol (2006) 1.87
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol (2007) 1.84
Xp54 and related (DDX6-like) RNA helicases: roles in messenger RNP assembly, translation regulation and RNA degradation. Nucleic Acids Res (2006) 1.83
Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps. Nat Struct Mol Biol (2009) 1.83
Biochemical identification of Xenopus Pumilio as a sequence-specific cyclin B1 mRNA-binding protein that physically interacts with a Nanos homolog, Xcat-2, and a cytoplasmic polyadenylation element-binding protein. J Biol Chem (2001) 1.81
Bone marrow transplantation reproduces the tristetraprolin-deficiency syndrome in recombination activating gene-2 (-/-) mice. Evidence that monocyte/macrophage progenitors may be responsible for TNFalpha overproduction. J Clin Invest (1997) 1.78
Immunological characterization of tristetraprolin as a low abundance, inducible, stable cytosolic protein. J Biol Chem (2004) 1.65
Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment. Mol Cell Biol (2010) 1.63
Tristetraprolin regulates CXCL1 (KC) mRNA stability. J Immunol (2008) 1.60
Real-time and quantitative imaging of mammalian stress granules and processing bodies. Methods Enzymol (2008) 1.55
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1. J Biol Chem (2003) 1.51
The control of mRNA stability in response to extracellular stimuli. Mol Cells (2002) 1.51
The ELAV protein HuD stimulates cap-dependent translation in a Poly(A)- and eIF4A-dependent manner. Mol Cell (2009) 1.27
Posttranscriptional control of type I interferon genes by KSRP in the innate immune response against viral infection. Mol Cell Biol (2011) 1.13
A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay. Nucleic Acids Res (2009) 1.03
Interleukin-1 activates synthesis of interleukin-6 by interfering with a KH-type splicing regulatory protein (KSRP)-dependent translational silencing mechanism. J Biol Chem (2011) 0.96
RNA-binding protein HuR is required for stabilization of SLC11A1 mRNA and SLC11A1 protein expression. Mol Cell Biol (2005) 0.95
Phosphorylation of human tristetraprolin in response to its interaction with the Cbl interacting protein CIN85. PLoS One (2010) 0.90
Septin1, a new interaction partner for human serine/threonine kinase aurora-B. Biochem Biophys Res Commun (2005) 0.87
Examining the influence of microRNAs on translation efficiency and on mRNA deadenylation and decay. Methods Enzymol (2008) 0.83
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell (2005) 9.01
Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med (2013) 8.76
Extended antiretroviral prophylaxis to reduce breast-milk HIV-1 transmission. N Engl J Med (2008) 8.19
Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway. Science (2008) 6.86
Clinical features of the initial cases of 2009 pandemic influenza A (H1N1) virus infection in China. N Engl J Med (2009) 6.45
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. N Engl J Med (2013) 5.22
Circulating microRNA: a novel potential biomarker for early diagnosis of acute myocardial infarction in humans. Eur Heart J (2010) 5.04
Prevalence of chronic obstructive pulmonary disease in China: a large, population-based survey. Am J Respir Crit Care Med (2007) 4.82
HST2 mediates SIR2-independent life-span extension by calorie restriction. Science (2005) 4.12
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation. Genes Dev (2006) 3.72
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet (2008) 3.62
Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting. Hepatology (2014) 3.40
Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression. Immunity (2007) 3.38
Cortical representations of olfactory input by trans-synaptic tracing. Nature (2010) 3.27
Statistical methods for testing effects on "maximum lifespan". Mech Ageing Dev (2004) 3.26
SOCS3 deletion promotes optic nerve regeneration in vivo. Neuron (2009) 3.22
Differential regulation of cell motility and invasion by FAK. J Cell Biol (2003) 3.15
Optimization of sensing and feedback control for vibration/flutter of rotating disk by PZT actuators via air coupled pressure. Sensors (Basel) (2011) 2.84
Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. Mol Cell Biol (2002) 2.70
Jurassic mimicry between a hangingfly and a ginkgo from China. Proc Natl Acad Sci U S A (2012) 2.56
Up-regulation of mitochondrial activity and acquirement of brown adipose tissue-like property in the white adipose tissue of fsp27 deficient mice. PLoS One (2008) 2.51
Early use of noninvasive positive pressure ventilation for acute lung injury: a multicenter randomized controlled trial. Crit Care Med (2012) 2.43
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet (2013) 2.39
Low-molecular-weight heparin and mortality in acutely ill medical patients. N Engl J Med (2011) 2.32
ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J Biol Chem (2007) 2.31
Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue. Proc Natl Acad Sci U S A (2013) 2.29
Postnatal HIV-1 transmission after cessation of infant extended antiretroviral prophylaxis and effect of maternal highly active antiretroviral therapy. J Infect Dis (2009) 2.26
Rare genetic variation at Zea mays crtRB1 increases beta-carotene in maize grain. Nat Genet (2010) 2.25
Frequency of gastroenteritis and gastroenteritis-associated mortality with early weaning in HIV-1-uninfected children born to HIV-infected women in Malawi. J Acquir Immune Defic Syndr (2010) 2.19
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription. J Cell Biol (2002) 2.14
Characterization of the bell-shaped vibratory angular rate gyro. Sensors (Basel) (2013) 2.04
High prevalence of macrolide resistance in Mycoplasma pneumoniae isolates from adult and adolescent patients with respiratory tract infection in China. Clin Infect Dis (2010) 2.02
ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection. Cell Microbiol (2008) 2.01
Relationship between syphilis and HIV infections among men who have sex with men in Beijing, China. Sex Transm Dis (2007) 2.00
MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer (2009) 1.99
Development of genome-wide DNA polymorphism database for map-based cloning of rice genes. Plant Physiol (2004) 1.98
Postexposure prophylaxis of breastfeeding HIV-exposed infants with antiretroviral drugs to age 14 weeks: updated efficacy results of the PEPI-Malawi trial. J Acquir Immune Defic Syndr (2011) 1.96
c-Myc rapidly induces acute myeloid leukemia in mice without evidence of lymphoma-associated antiapoptotic mutations. Blood (2005) 1.96
InterDom: a database of putative interacting protein domains for validating predicted protein interactions and complexes. Nucleic Acids Res (2003) 1.94
The RNA-binding protein IMP-3 is a translational activator of insulin-like growth factor II leader-3 mRNA during proliferation of human K562 leukemia cells. J Biol Chem (2005) 1.94
Cutting edge: TNF-induced microRNAs regulate TNF-induced expression of E-selectin and intercellular adhesion molecule-1 on human endothelial cells: feedback control of inflammation. J Immunol (2009) 1.93
Atypical presentations among Medicare beneficiaries with unstable angina pectoris. Am J Cardiol (2002) 1.92
Sensitive capture of circulating tumour cells by functionalized graphene oxide nanosheets. Nat Nanotechnol (2013) 1.92
Mammographic density as a surrogate marker for the effects of hormone therapy on risk of breast cancer. Cancer Epidemiol Biomarkers Prev (2006) 1.91
Independent effect of depression and anxiety on chronic obstructive pulmonary disease exacerbations and hospitalizations. Am J Respir Crit Care Med (2008) 1.90
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis. J Gastroenterol Hepatol (2011) 1.86
Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J Biol Chem (2006) 1.86
Disruption of response regulator gene, devR, leads to attenuation in virulence of Mycobacterium tuberculosis. FEMS Microbiol Lett (2004) 1.86
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS One (2009) 1.86
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins. J Cell Biol (2004) 1.86
G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. Am J Physiol Cell Physiol (2004) 1.85
Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation. Nat Struct Mol Biol (2007) 1.84
Epigenetic and genetic influences on DNA methylation variation in maize populations. Plant Cell (2013) 1.83
Quasi-ballistic thermal transport from nanoscale interfaces observed using ultrafast coherent soft X-ray beams. Nat Mater (2009) 1.83
Role of PI3K/AKT/mTOR signaling in the cell cycle progression of human prostate cancer. Biochem Biophys Res Commun (2003) 1.82
Performance comparison and evaluation of software tools for microRNA deep-sequencing data analysis. Nucleic Acids Res (2012) 1.80
Proteomic fingerprints for potential application to early diagnosis of severe acute respiratory syndrome. Clin Chem (2004) 1.76
N-Myc downstream-regulated gene 2 (NDRG2) inhibits glioblastoma cell proliferation. Int J Cancer (2003) 1.75
Deep sequencing discovery of novel and conserved microRNAs in trifoliate orange (Citrus trifoliata). BMC Genomics (2010) 1.74
Crystal structure of the swine-origin A (H1N1)-2009 influenza A virus hemagglutinin (HA) reveals similar antigenicity to that of the 1918 pandemic virus. Protein Cell (2010) 1.74
Extracellular signal-regulated kinase signaling pathway regulates breast cancer cell migration by maintaining slug expression. Cancer Res (2009) 1.74
Fertility intentions of HIV-1 infected and uninfected women in Malawi: a longitudinal study. AIDS Behav (2009) 1.73
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras. Nature (2009) 1.72
Wide-field fast-scanning photoacoustic microscopy based on a water-immersible MEMS scanning mirror. J Biomed Opt (2012) 1.71
Protein kinase C delta is required for p47phox phosphorylation and translocation in activated human monocytes. J Immunol (2004) 1.68
Characteristics of the interaction of a synthetic human tristetraprolin tandem zinc finger peptide with AU-rich element-containing RNA substrates. J Biol Chem (2003) 1.67
Research on bell-shaped vibratory angular rate gyro's character of resonator. Sensors (Basel) (2013) 1.66
B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS. J Exp Med (2014) 1.65
Integrative approach for computationally inferring protein domain interactions. Bioinformatics (2003) 1.63
Cideb regulates diet-induced obesity, liver steatosis, and insulin sensitivity by controlling lipogenesis and fatty acid oxidation. Diabetes (2007) 1.62
Asymptomatic patients of chronic obstructive pulmonary disease in China. Chin Med J (Engl) (2010) 1.62
Positive regulation of interferon regulatory factor 3 activation by Herc5 via ISG15 modification. Mol Cell Biol (2010) 1.61
Conversion of human fibroblasts to functional endothelial cells by defined factors. Arterioscler Thromb Vasc Biol (2013) 1.61
Regulation of aurora B expression by the bromodomain protein Brd4. Mol Cell Biol (2009) 1.60
Curcumin, a dietary component, has anticancer, chemosensitization, and radiosensitization effects by down-regulating the MDM2 oncogene through the PI3K/mTOR/ETS2 pathway. Cancer Res (2007) 1.60
Investigation of the relationships between immune-mediated inhibition of mycobacterial growth and other potential surrogate markers of protective Mycobacterium tuberculosis immunity. J Infect Dis (2002) 1.59
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes. Proc Natl Acad Sci U S A (2013) 1.59
Development of receptor for advanced glycation end products-directed imaging of atherosclerotic plaque in a murine model of spontaneous atherosclerosis. Circ Cardiovasc Imaging (2008) 1.58
Construction of a chloroplast protein interaction network and functional mining of photosynthetic proteins in Arabidopsis thaliana. Cell Res (2008) 1.58
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat Struct Mol Biol (2011) 1.58
Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis. Plant J (2007) 1.58
Cideb, an ER- and lipid droplet-associated protein, mediates VLDL lipidation and maturation by interacting with apolipoprotein B. Cell Metab (2009) 1.57
A theoretical model to predict both horizontal displacement and vertical displacement for electromagnetic induction-based deep displacement sensors. Sensors (Basel) (2011) 1.53
Racial differences in thoracic aorta atherosclerosis among ischemic stroke patients. Stroke (2003) 1.53
Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. J Immunol (2009) 1.52
Regulation of A + U-rich element-directed mRNA turnover involving reversible phosphorylation of AUF1. J Biol Chem (2003) 1.51
Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China. Respirology (2010) 1.50
Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis. Blood (2008) 1.50
Posttranscriptional derepression of GADD45alpha by genotoxic stress. Mol Cell (2006) 1.50
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury. Circulation (2006) 1.48
Infrared nanoscopy of dirac plasmons at the graphene-SiO₂ interface. Nano Lett (2011) 1.46
The regulation of mRNA stability in mammalian cells: 2.0. Gene (2012) 1.46
TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response. J Immunol (2009) 1.45