25 years of epidermal stem cell research.

PubWeight™: 1.70‹?› | Rank: Top 3%

🔗 View Article (PMC 3998762)

Published in J Invest Dermatol on December 29, 2011

Authors

Ruby Ghadially1

Author Affiliations

1: Department of Dermatology and Epithelial Section, UCSF Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, California 94121, USA. ghadiallyr@derm.ucsf.edu

Articles citing this

Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately. Stem Cell Res Ther (2015) 1.57

Epithelial stem cells and implications for wound repair. Semin Cell Dev Biol (2012) 1.35

Keratinocytes propagated in serum-free, feeder-free culture conditions fail to form stratified epidermis in a reconstituted skin model. PLoS One (2013) 0.93

Keratin k15 as a biomarker of epidermal stem cells. Int J Mol Sci (2013) 0.92

Role of stat3 in skin carcinogenesis: insights gained from relevant mouse models. J Skin Cancer (2013) 0.86

Deregulation of epidermal stem cell niche contributes to pathogenesis of nonhealing venous ulcers. Wound Repair Regen (2014) 0.81

Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling. J Histochem Cytochem (2014) 0.79

Isolation and characterization of squamous cell carcinoma-derived stem-like cells: role in tumor formation. Int J Mol Sci (2013) 0.79

Interfollicular epidermal homeostasis: a response to Ghadially, '25 years of epidermal stem cell research'. J Invest Dermatol (2012) 0.79

The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells. Development (2014) 0.77

Oriented cell division: new roles in guiding skin wound repair and regeneration. Biosci Rep (2015) 0.77

Identifying the stem cell. J Invest Dermatol (2014) 0.76

Epidermal stem cells (ESCs) accelerate diabetic wound healing via the Notch signalling pathway. Biosci Rep (2016) 0.76

Gelatin-based Hydrogel Degradation and Tissue Interaction in vivo: Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice. Theranostics (2016) 0.75

Insight into skin cell-based osteogenesis: a review. F1000Res (2017) 0.75

Nanog down-regulates the Wnt signaling pathway via β-catenin phosphorylation during epidermal stem cell proliferation and differentiation. Cell Biosci (2015) 0.75

Esophageal human β-defensin expression in eosinophilic esophagitis. Pediatr Res (2013) 0.75

Articles cited by this

(truncated to the top 100)

Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A (2003) 59.17

ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome. Cell Stem Cell (2007) 22.89

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 21.59

A direct measurement of the radiation sensitivity of normal mouse bone marrow cells. Radiat Res (1961) 18.57

Generation of a functional mammary gland from a single stem cell. Nature (2006) 18.30

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature (2000) 16.75

Purification and characterization of mouse hematopoietic stem cells. Science (1988) 15.99

Defining the epithelial stem cell niche in skin. Science (2003) 14.93

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature (2003) 14.35

Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell (1997) 12.60

Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell (1990) 12.13

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A (2007) 11.94

Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell (2008) 11.53

Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat Biotechnol (2008) 10.63

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis. J Immunol (1981) 9.86

The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity (1994) 9.50

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt. Development (1990) 8.37

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis. Nat Med (2005) 8.01

Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95

Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet (2008) 7.55

Notch signaling. Science (1995) 7.22

Asymmetric cell divisions promote stratification and differentiation of mammalian skin. Nature (2005) 6.67

p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell (2007) 6.50

Morphogenesis and renewal of hair follicles from adult multipotent stem cells. Cell (2001) 6.37

A single type of progenitor cell maintains normal epidermis. Nature (2007) 6.32

Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci U S A (1987) 6.30

p63 identifies keratinocyte stem cells. Proc Natl Acad Sci U S A (2001) 6.07

Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell (1993) 5.86

Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells (2007) 5.83

Mechanisms of asymmetric stem cell division. Cell (2008) 5.59

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34. J Invest Dermatol (2003) 5.28

Stem cell patterning and fate in human epidermis. Cell (1995) 5.22

A niche maintaining germ line stem cells in the Drosophila ovary. Science (2000) 5.04

Age-associated characteristics of murine hematopoietic stem cells. J Exp Med (2000) 4.65

Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci U S A (2008) 4.48

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science (2010) 4.45

Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer. Cell Stem Cell (2010) 4.18

The tortoise and the hair: slow-cycling cells in the stem cell race. Cell (2009) 3.90

Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment. Science (2011) 3.89

Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis. Development (2003) 3.84

p63 regulates proliferation and differentiation of developmentally mature keratinocytes. Genes Dev (2006) 3.66

Asymmetric cell divisions promote Notch-dependent epidermal differentiation. Nature (2011) 3.64

Properties of haematopoietic stem cells surviving 5-fluorouracil treatment: evidence for a pre-CFU-S cell? Nature (1979) 3.56

Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood (2005) 3.51

Canonical notch signaling functions as a commitment switch in the epidermal lineage. Genes Dev (2006) 3.51

Epithelial stem cells: a folliculocentric view. J Invest Dermatol (2006) 3.49

Competitive repopulation: a new assay for long-term stem cell functional capacity. Blood (1980) 3.49

Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis. Cell Stem Cell (2009) 3.44

Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy. Proc Natl Acad Sci U S A (1990) 3.43

Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood (2004) 3.41

Characterization and isolation of stem cell-enriched human hair follicle bulge cells. J Clin Invest (2006) 3.41

THE DISTRIBUTION OF COLONY-FORMING CELLS AMONG SPLEEN COLONIES. J Cell Physiol (1963) 3.36

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene. Nature (2003) 3.25

SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood (2005) 3.22

Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell (1992) 3.20

Resting and activated subsets of mouse multipotent hematopoietic stem cells. Proc Natl Acad Sci U S A (1990) 3.19

Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion. Stem Cells (2004) 3.15

Lack of a fusion requirement for development of bone marrow-derived epithelia. Science (2004) 3.14

Clonal analysis of hematopoietic stem-cell differentiation in vivo. Proc Natl Acad Sci U S A (1991) 3.14

Enrichment for murine keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A (2000) 3.12

Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells. Nat Med (2006) 3.11

Epithelial stem cells in vivo. J Cell Sci Suppl (1988) 2.99

Location of stem cells of human hair follicles by clonal analysis. Cell (1994) 2.96

Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci U S A (2006) 2.91

Identification and isolation of candidate human keratinocyte stem cells based on cell surface phenotype. Proc Natl Acad Sci U S A (1998) 2.91

Multiple classes of stem cells in cutaneous epithelium: a lineage analysis of adult mouse skin. EMBO J (2001) 2.89

Limiting factors in murine hematopoietic stem cell assays. Cell Stem Cell (2007) 2.89

Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity. Stem Cells (2004) 2.80

Contribution of bone marrow-derived cells to skin: collagen deposition and wound repair. Stem Cells (2004) 2.70

gamma-secretase functions through Notch signaling to maintain skin appendages but is not required for their patterning or initial morphogenesis. Dev Cell (2004) 2.68

Stem cell concepts. Differentiation (1979) 2.67

Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers. Proc Natl Acad Sci U S A (1990) 2.59

Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters. Curr Biol (2000) 2.58

The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J Cell Sci (1998) 2.58

An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution. J Invest Dermatol (2007) 2.53

p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A (2007) 2.31

Studies of hematopoietic stem cells spared by 5-fluorouracil. J Exp Med (1984) 2.29

Notch tumor suppressor function. Oncogene (2008) 2.26

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor. Mol Cell Biol (1997) 2.12

Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage. J Cell Sci (1996) 2.04

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells. Development (2006) 2.04

Selection and extended growth of murine epidermal stem cells in culture. Exp Cell Res (1998) 2.02

The epidermal proliferative unit: the possible role of the central basal cell. Cell Tissue Kinet (1974) 2.02

Epidermal Notch signalling: differentiation, cancer and adhesion. Curr Opin Cell Biol (2008) 1.99

Participation of bone marrow derived cells in cutaneous wound healing. J Cell Physiol (2003) 1.99

Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype. J Investig Dermatol Symp Proc (1999) 1.96

5-Fluorouracil spares hemopoietic stem cells responsible for long-term repopulation. Exp Hematol (1990) 1.96

Retroviral transduction of murine epidermal stem cells demonstrates clonal units of epidermal structure. J Invest Dermatol (1997) 1.91

Sic transit gloria: farewell to the epidermal transit amplifying cell? Cell Stem Cell (2007) 1.91

Ordered structure of the stratum corneum of mammalian skin. Nature (1969) 1.90

Identification and behavior of label-retaining cells in oral mucosa and skin. J Dent Res (1981) 1.88

Side population keratinocytes resembling bone marrow side population stem cells are distinct from label-retaining keratinocyte stem cells. J Invest Dermatol (2003) 1.83

Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells. J Clin Invest (2011) 1.81

Concise review: bone marrow-derived stem/progenitor cells in cutaneous repair and regeneration. Stem Cells (2010) 1.78

Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells. J Cell Sci (2005) 1.75

The control of epidermal stem cells (holoclones) in the treatment of massive full-thickness burns with autologous keratinocytes cultured on fibrin. Transplantation (1999) 1.67

Induced pluripotent stem cells from individuals with recessive dystrophic epidermolysis bullosa. J Invest Dermatol (2010) 1.62

Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage. Blood (1992) 1.60

Designer skin: lineage commitment in postnatal epidermis. Trends Cell Biol (2002) 1.59