Published in J Am Chem Soc on January 24, 2012
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A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis. Mol Cell Proteomics (2014) 0.92
Identification and interrogation of combinatorial histone modifications. Front Genet (2013) 0.91
Integrative chemical biology approaches for identification and characterization of "erasers" for fatty-acid-acylated lysine residues within proteins. Angew Chem Int Ed Engl (2014) 0.89
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Combining genomic and proteomic approaches for epigenetics research. Epigenomics (2013) 0.83
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Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS. Mol Biosyst (2012) 0.78
Histone-binding domains: strategies for discovery and characterization. Biochim Biophys Acta (2014) 0.77
Identification of Posttranslational Modification-Dependent Protein Interactions Using Yeast Surface Displayed Human Proteome Libraries. Methods Mol Biol (2015) 0.76
Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. Proc Natl Acad Sci U S A (2016) 0.76
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The structured core of human β tubulin confers isotype-specific polymerization properties. J Cell Biol (2016) 0.75
MORC3, a Component of PML Nuclear Bodies, Has a Role in Restricting Herpes Simplex Virus 1 and Human Cytomegalovirus. J Virol (2016) 0.75
Middle-Down and Chemical Proteomic Approaches to Reveal Histone H4 Modification Dynamics in Cell Cycle: Label-Free Semi-Quantification of Histone Tail Peptide Modifications Including Phosphorylation and Highly Sensitive Capture of Histone PTM Binding Proteins Using Photo-Reactive Crosslinkers. Mass Spectrom (Tokyo) (2015) 0.75
Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase. Cell Rep (2016) 0.75
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Site-specific azide-acetyllysine photochemistry on epigenetic readers for interactome profiling. Chem Sci (2017) 0.75
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Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A. Science (2006) 4.54
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Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell (2010) 3.25
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Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex. Mol Cell (2008) 2.09
Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3. Structure (2008) 1.72
HBO1 HAT complexes target chromatin throughout gene coding regions via multiple PHD finger interactions with histone H3 tail. Mol Cell (2009) 1.58
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Structural insight into the zinc finger CW domain as a histone modification reader. Structure (2010) 1.30
The CW domain, a new histone recognition module in chromatin proteins. EMBO J (2011) 1.01
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Protein- and immunoaffinity purification of multiprotein complexes. Methods Enzymol (2002) 0.82
X-ray structure of a voltage-dependent K+ channel. Nature (2003) 14.50
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature (2006) 10.73
Crystal structure and mechanism of a calcium-gated potassium channel. Nature (2002) 10.03
X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of anion selectivity. Nature (2002) 9.96
The open pore conformation of potassium channels. Nature (2002) 9.09
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science (2011) 9.00
The molecular architecture of the nuclear pore complex. Nature (2007) 6.93
Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex. Nat Cell Biol (2009) 6.69
Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol (2002) 6.38
Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. Cell (2005) 6.12
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement. Nat Immunol (2002) 5.67
Correcting improper chromosome-spindle attachments during cell division. Nat Cell Biol (2004) 5.18
Determining the architectures of macromolecular assemblies. Nature (2007) 4.94
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks. Nature (2005) 4.63
The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2. Mol Cell (2002) 3.99
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration. Proc Natl Acad Sci U S A (2007) 3.92
Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell (2006) 3.87
Midzone activation of aurora B in anaphase produces an intracellular phosphorylation gradient. Nature (2008) 3.77
Methylation of a histone mimic within the histone methyltransferase G9a regulates protein complex assembly. Mol Cell (2007) 3.51
Monastrol inhibition of the mitotic kinesin Eg5. J Biol Chem (2005) 3.49
Crystal structure of a Kir3.1-prokaryotic Kir channel chimera. EMBO J (2007) 3.31
ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination. Plant J (2002) 3.28
Induction of autophagy in axonal dystrophy and degeneration. J Neurosci (2006) 3.28
The human mitotic checkpoint protein BubR1 regulates chromosome-spindle attachments. Nat Cell Biol (2004) 3.27
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex. Genes Dev (2004) 3.25
Par6alpha signaling controls glial-guided neuronal migration. Nat Neurosci (2004) 3.06
Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science (2013) 3.02
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore. Nat Rev Mol Cell Biol (2013) 3.01
Fluorescent proteins as proteomic probes. Mol Cell Proteomics (2005) 2.98
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Determining the position of the cell division plane. Nature (2003) 2.80
Virtual gating and nuclear transport: the hole picture. Trends Cell Biol (2003) 2.68
Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J Cell Biol (2006) 2.63
Comprehensive analysis of diverse ribonucleoprotein complexes. Nat Methods (2007) 2.55
Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell (2010) 2.50
Dynein/dynactin regulate metaphase spindle length by targeting depolymerizing activities to spindle poles. J Cell Biol (2004) 2.46
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini. Proc Natl Acad Sci U S A (2007) 2.43
Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging. Nat Cell Biol (2007) 2.40
TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem (2004) 2.36
Simple fold composition and modular architecture of the nuclear pore complex. Proc Natl Acad Sci U S A (2006) 2.35
A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics (2011) 2.34
Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis. J Cell Biol (2003) 2.33
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein. Nature (2012) 2.16
Chromatin-bound Xenopus Dppa2 shapes the nucleus by locally inhibiting microtubule assembly. Dev Cell (2013) 2.09
Tracking and elucidating alphavirus-host protein interactions. J Biol Chem (2006) 2.01
Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. Proc Natl Acad Sci U S A (2005) 1.97
Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation. Proc Natl Acad Sci U S A (2006) 1.95
Proteomic and genomic characterization of chromatin complexes at a boundary. J Cell Biol (2005) 1.92
E protein silencing by the leukemogenic AML1-ETO fusion protein. Science (2004) 1.89
Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature (2008) 1.89
I-DIRT, a general method for distinguishing between specific and nonspecific protein interactions. J Proteome Res (2005) 1.87
Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase. Nat Cell Biol (2011) 1.86
Marking and measuring single microtubules by PRC1 and kinesin-4. Cell (2013) 1.86
MED1/TRAP220 exists predominantly in a TRAP/ Mediator subpopulation enriched in RNA polymerase II and is required for ER-mediated transcription. Mol Cell (2005) 1.85
Human cytomegalovirus protein UL38 inhibits host cell stress responses by antagonizing the tuberous sclerosis protein complex. Cell Host Microbe (2008) 1.85
A modular cross-linking approach for exploring protein interactions. J Am Chem Soc (2003) 1.85
Microtubule cross-linking triggers the directional motility of kinesin-5. J Cell Biol (2008) 1.83
hTPX2 is required for normal spindle morphology and centrosome integrity during vertebrate cell division. Curr Biol (2002) 1.82
Allosteric inhibition of kinesin-5 modulates its processive directional motility. Nat Chem Biol (2006) 1.81
Regulation of class switch recombination and somatic mutation by AID phosphorylation. J Exp Med (2008) 1.78
Simple kinetic relationships and nonspecific competition govern nuclear import rates in vivo. J Cell Biol (2006) 1.78
Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein. J Virol (2010) 1.78
Identification of SMARCAL1 as a component of the DNA damage response. J Biol Chem (2009) 1.74
Evidence for a shared nuclear pore complex architecture that is conserved from the last common eukaryotic ancestor. Mol Cell Proteomics (2009) 1.74
Examining how the spatial organization of chromatin signals influences metaphase spindle assembly. Nat Cell Biol (2006) 1.70
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientation. Nat Cell Biol (2011) 1.69
Long range allosteric control of cytoplasmic dynein ATPase activity by the stalk and C-terminal domains. J Biol Chem (2005) 1.68
Probing cell-division phenotype space and Polo-like kinase function using small molecules. Nat Chem Biol (2006) 1.65
Ku80 removal from DNA through double strand break-induced ubiquitylation. J Cell Biol (2008) 1.64
The centromere geometry essential for keeping mitosis error free is controlled by spindle forces. Nature (2007) 1.64
Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex. Proc Natl Acad Sci U S A (2007) 1.64
Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry. Proc Natl Acad Sci U S A (2003) 1.63
The mobile nucleoporin Nup2p and chromatin-bound Prp20p function in endogenous NPC-mediated transcriptional control. J Cell Biol (2005) 1.59
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5. Chem Biol (2002) 1.58
Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1. J Biol Chem (2005) 1.57
Targeted proteomic study of the cyclin-Cdk module. Mol Cell (2004) 1.56
Structure of microcin J25, a peptide inhibitor of bacterial RNA polymerase, is a lassoed tail. J Am Chem Soc (2003) 1.56
Synergistic functions of SII and p300 in productive activator-dependent transcription of chromatin templates. Cell (2006) 1.54
Using transcriptome sequencing to identify mechanisms of drug action and resistance. Nat Chem Biol (2012) 1.53
Polo-like kinase controls vertebrate spindle elongation and cytokinesis. PLoS One (2007) 1.53
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs. J Clin Invest (2016) 1.53
Analysis of protein phosphorylation by hypothesis-driven multiple-stage mass spectrometry. Anal Chem (2004) 1.52
RNA ligase RtcB splices 3'-phosphate and 5'-OH ends via covalent RtcB-(histidinyl)-GMP and polynucleotide-(3')pp(5')G intermediates. Proc Natl Acad Sci U S A (2012) 1.51
A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation. Chem Biol (2013) 1.50
Carbon dioxide-induced anesthesia results in a rapid increase in plasma levels of vasopressin. Endocrinology (2009) 1.49
Improved beta-elimination-based affinity purification strategy for enrichment of phosphopeptides. Anal Chem (2003) 1.48
GINS motion reveals replication fork progression is remarkably uniform throughout the yeast genome. Mol Syst Biol (2010) 1.45
A nonmotor microtubule binding site in kinesin-5 is required for filament crosslinking and sliding. Curr Biol (2011) 1.45
Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol (2012) 1.44
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction. Proc Natl Acad Sci U S A (2010) 1.41
SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. J Biol Chem (2001) 1.40
Efficiency, selectivity, and robustness of nucleocytoplasmic transport. PLoS Comput Biol (2007) 1.39
Mechanistic analysis of the mitotic kinesin Eg5. J Biol Chem (2004) 1.38
Host factors associated with the Sindbis virus RNA-dependent RNA polymerase: role for G3BP1 and G3BP2 in virus replication. J Virol (2010) 1.38
Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease. PLoS One (2011) 1.38
Smyd2 controls cytoplasmic lysine methylation of Hsp90 and myofilament organization. Genes Dev (2012) 1.38
Dual detection of chromosomes and microtubules by the chromosomal passenger complex drives spindle assembly. Dev Cell (2010) 1.34