| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial.
|
Lancet
|
2012
|
9.86
|
|
2
|
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens.
|
Circulation
|
2007
|
8.62
|
|
3
|
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization.
|
Nat Genet
|
2006
|
6.39
|
|
4
|
Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction.
|
Circulation
|
2007
|
5.09
|
|
5
|
Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice.
|
Circ Res
|
2010
|
4.19
|
|
6
|
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes.
|
J Biol Chem
|
2003
|
3.93
|
|
7
|
Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells.
|
J Am Coll Cardiol
|
2012
|
3.48
|
|
8
|
Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy.
|
Circulation
|
2009
|
3.45
|
|
9
|
Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers.
|
Circulation
|
2004
|
3.20
|
|
10
|
Late gadolinium enhancement by cardiovascular magnetic resonance heralds an adverse prognosis in nonischemic cardiomyopathy.
|
J Am Coll Cardiol
|
2008
|
2.99
|
|
11
|
Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue.
|
PLoS One
|
2009
|
2.89
|
|
12
|
Biological pacemaker created by gene transfer.
|
Nature
|
2002
|
2.83
|
|
13
|
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice.
|
J Clin Invest
|
2002
|
2.74
|
|
14
|
Combined cardiac magnetic resonance imaging and C-reactive protein levels identify a cohort at low risk for defibrillator firings and death.
|
Circ Cardiovasc Imaging
|
2012
|
2.62
|
|
15
|
Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations.
|
Circulation
|
2009
|
2.55
|
|
16
|
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics.
|
Biophys J
|
2003
|
2.52
|
|
17
|
Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation.
|
Circ Res
|
2005
|
2.44
|
|
18
|
Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart.
|
Circulation
|
2008
|
2.37
|
|
19
|
Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography.
|
J Am Coll Cardiol
|
2008
|
2.33
|
|
20
|
Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction.
|
Circ Res
|
2010
|
2.33
|
|
21
|
Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells.
|
Circulation
|
2011
|
2.29
|
|
22
|
Cardiac cell therapy: where we've been, where we are, and where we should be headed.
|
Br Med Bull
|
2011
|
2.26
|
|
23
|
Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways.
|
Circ Res
|
2006
|
2.20
|
|
24
|
Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery.
|
J Am Coll Cardiol
|
2009
|
2.20
|
|
25
|
Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells.
|
J Physiol
|
2002
|
2.18
|
|
26
|
Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction.
|
J Am Coll Cardiol
|
2011
|
2.15
|
|
27
|
Cardioprotection by N-acetylglucosamine linkage to cellular proteins.
|
Circulation
|
2008
|
2.11
|
|
28
|
Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair.
|
Stem Cells
|
2010
|
2.10
|
|
29
|
Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel.
|
Mol Cell
|
2004
|
2.05
|
|
30
|
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart.
|
EMBO Mol Med
|
2013
|
2.04
|
|
31
|
Assessment and optimization of cell engraftment after transplantation into the heart.
|
Circ Res
|
2010
|
1.90
|
|
32
|
Dedifferentiation and proliferation of mammalian cardiomyocytes.
|
PLoS One
|
2010
|
1.89
|
|
33
|
Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes.
|
Circ Res
|
2003
|
1.89
|
|
34
|
Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies.
|
J Mol Cell Cardiol
|
2010
|
1.88
|
|
35
|
Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart.
|
Circ Res
|
2004
|
1.87
|
|
36
|
Endogenous cardiac stem cells.
|
Prog Cardiovasc Dis
|
2007
|
1.79
|
|
37
|
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression.
|
J Clin Invest
|
2003
|
1.78
|
|
38
|
Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18.
|
Nat Biotechnol
|
2012
|
1.74
|
|
39
|
Disproportionate enhancement of myocardial contractility by the xanthine oxidase inhibitor oxypurinol in failing rat myocardium.
|
Cardiovasc Res
|
2003
|
1.70
|
|
40
|
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart.
|
Circ Res
|
2002
|
1.70
|
|
41
|
A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte.
|
Biophys J
|
2006
|
1.69
|
|
42
|
CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart.
|
Proc Natl Acad Sci U S A
|
2008
|
1.66
|
|
43
|
Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells.
|
Stem Cells
|
2010
|
1.63
|
|
44
|
Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin.
|
Circ Res
|
2002
|
1.62
|
|
45
|
Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity.
|
Proc Natl Acad Sci U S A
|
2004
|
1.60
|
|
46
|
Magnetic resonance-based anatomical analysis of scar-related ventricular tachycardia: implications for catheter ablation.
|
Circ Res
|
2007
|
1.58
|
|
47
|
ECG quantification of myocardial scar in cardiomyopathy patients with or without conduction defects: correlation with cardiac magnetic resonance and arrhythmogenesis.
|
Circ Arrhythm Electrophysiol
|
2008
|
1.55
|
|
48
|
Biological pacemaker created by percutaneous gene delivery via venous catheters in a porcine model of complete heart block.
|
Heart Rhythm
|
2012
|
1.54
|
|
49
|
Mixed results for bone marrow–derived cell therapy for ischemic heart disease.
|
JAMA
|
2012
|
1.53
|
|
50
|
Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model.
|
Circulation
|
2006
|
1.52
|
|
51
|
Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction.
|
Circulation
|
2013
|
1.51
|
|
52
|
Kidney-derived stromal cells modulate dendritic and T cell responses.
|
J Am Soc Nephrol
|
2009
|
1.51
|
|
53
|
Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat.
|
Am J Physiol Heart Circ Physiol
|
2002
|
1.49
|
|
54
|
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair.
|
Cardiovasc Res
|
2010
|
1.41
|
|
55
|
Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia.
|
Ann Thorac Surg
|
2002
|
1.41
|
|
56
|
Molecular correlates of altered expression of potassium currents in failing rabbit myocardium.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.39
|
|
57
|
Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals.
|
PLoS Genet
|
2011
|
1.38
|
|
58
|
Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes.
|
Proteomics
|
2010
|
1.38
|
|
59
|
Human cardiospheres are a source of stem cells with cardiomyogenic potential.
|
Stem Cells
|
2010
|
1.33
|
|
60
|
Allogeneic cardiospheres safely boost cardiac function and attenuate adverse remodeling after myocardial infarction in immunologically mismatched rat strains.
|
J Am Coll Cardiol
|
2013
|
1.28
|
|
61
|
Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers.
|
Cardiovasc Res
|
2005
|
1.28
|
|
62
|
Magnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusion.
|
Cell Transplant
|
2012
|
1.28
|
|
63
|
Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes.
|
Circ Res
|
2003
|
1.26
|
|
64
|
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy.
|
Circ Res
|
2004
|
1.24
|
|
65
|
Gene therapy to inhibit the calcium channel beta subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy.
|
Circ Res
|
2007
|
1.24
|
|
66
|
Physiological determinants of contractile force generation and calcium handling in mouse myocardium.
|
J Mol Cell Cardiol
|
2002
|
1.23
|
|
67
|
Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices?
|
Circ Res
|
2010
|
1.21
|
|
68
|
Stem cells in the heart: what's the buzz all about? Part 2: Arrhythmic risks and clinical studies.
|
Heart Rhythm
|
2008
|
1.19
|
|
69
|
Is Kir6.1 a subunit of mitoK(ATP)?
|
Biochem Biophys Res Commun
|
2007
|
1.19
|
|
70
|
Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity.
|
Am J Physiol Heart Circ Physiol
|
2007
|
1.18
|
|
71
|
Cardioprotective role of the mitochondrial ATP-binding cassette protein 1.
|
Circ Res
|
2005
|
1.17
|
|
72
|
Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization.
|
Circ Res
|
2002
|
1.15
|
|
73
|
Differential actions of cardioprotective agents on the mitochondrial death pathway.
|
Circ Res
|
2003
|
1.14
|
|
74
|
Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel.
|
Biomaterials
|
2012
|
1.14
|
|
75
|
Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells.
|
Mol Ther
|
2008
|
1.13
|
|
76
|
Brief report: Mechanism of extravasation of infused stem cells.
|
Stem Cells
|
2012
|
1.13
|
|
77
|
Simvastatin attenuates oxidant-induced mitochondrial dysfunction in cardiac myocytes.
|
Circ Res
|
2003
|
1.12
|
|
78
|
Stem cells in the heart: what's the buzz all about?--Part 1: preclinical considerations.
|
Heart Rhythm
|
2008
|
1.11
|
|
79
|
Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway.
|
Circulation
|
2003
|
1.10
|
|
80
|
Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration.
|
Integr Biol (Camb)
|
2012
|
1.08
|
|
81
|
IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers.
|
Circ Res
|
2009
|
1.07
|
|
82
|
Cellular and molecular determinants of altered Ca2+ handling in the failing rabbit heart: primary defects in SR Ca2+ uptake and release mechanisms.
|
Am J Physiol Heart Circ Physiol
|
2006
|
1.05
|
|
83
|
Xanthine oxidase inhibitors improve energetics and function after infarction in failing mouse hearts.
|
Am J Physiol Heart Circ Physiol
|
2005
|
1.04
|
|
84
|
Transcriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytes.
|
J Biol Chem
|
2011
|
1.04
|
|
85
|
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction.
|
J Am Coll Cardiol
|
2008
|
1.04
|
|
86
|
Myocardial substrate and route of administration determine acute cardiac retention and lung bio-distribution of cardiosphere-derived cells.
|
J Nucl Cardiol
|
2011
|
1.02
|
|
87
|
Antiapoptotic effect of nicorandil mediated by mitochondrial atp-sensitive potassium channels in cultured cardiac myocytes.
|
J Am Coll Cardiol
|
2002
|
1.02
|
|
88
|
Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy.
|
Circ Res
|
2007
|
1.02
|
|
89
|
Spiral waves and reentry dynamics in an in vitro model of the healed infarct border zone.
|
Circ Res
|
2009
|
1.02
|
|
90
|
Gene transfer of a synthetic pacemaker channel into the heart: a novel strategy for biological pacing.
|
Circulation
|
2006
|
1.00
|
|
91
|
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction.
|
J Clin Invest
|
2015
|
1.00
|
|
92
|
Transplantation of platelet gel spiked with cardiosphere-derived cells boosts structural and functional benefits relative to gel transplantation alone in rats with myocardial infarction.
|
Biomaterials
|
2012
|
1.00
|
|
93
|
Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells.
|
Stem Cells
|
2014
|
0.99
|
|
94
|
Creation of a biological pacemaker by cell fusion.
|
Circ Res
|
2007
|
0.99
|
|
95
|
Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels.
|
J Biol Chem
|
2002
|
0.98
|
|
96
|
Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress.
|
Stroke
|
2003
|
0.98
|
|
97
|
Enhanced infarct border zone function and altered mechanical activation predict inducibility of monomorphic ventricular tachycardia in patients with ischemic cardiomyopathy.
|
Radiology
|
2007
|
0.97
|
|
98
|
Dose-dependent functional benefit of human cardiosphere transplantation in mice with acute myocardial infarction.
|
J Cell Mol Med
|
2012
|
0.96
|
|
99
|
Heart to heart: The elusive mechanism of cell therapy.
|
Circulation
|
2010
|
0.96
|
|
100
|
Murine strain differences in contractile function are temperature- and frequency-dependent.
|
Pflugers Arch
|
2006
|
0.95
|
|
101
|
Dynamics of early afterdepolarization-mediated triggered activity in cardiac monolayers.
|
Biophys J
|
2012
|
0.95
|
|
102
|
Intramyocardial injection of platelet gel promotes endogenous repair and augments cardiac function in rats with myocardial infarction.
|
J Am Coll Cardiol
|
2012
|
0.95
|
|
103
|
Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-β signaling.
|
Basic Res Cardiol
|
2014
|
0.94
|
|
104
|
Intrinsic cardiac origin of human cardiosphere-derived cells.
|
Eur Heart J
|
2011
|
0.93
|
|
105
|
Redox signaling and protein phosphorylation in mitochondria: progress and prospects.
|
J Bioenerg Biomembr
|
2009
|
0.93
|
|
106
|
Cardiospheres and cardiosphere-derived cells as therapeutic agents following myocardial infarction.
|
Expert Rev Cardiovasc Ther
|
2012
|
0.92
|
|
107
|
Dual gene therapy with SERCA1 and Kir2.1 abbreviates excitation without suppressing contractility.
|
J Clin Invest
|
2002
|
0.92
|
|
108
|
VAMP-1, VAMP-2, and syntaxin-4 regulate ANP release from cardiac myocytes.
|
J Mol Cell Cardiol
|
2010
|
0.91
|
|
109
|
Functional impairment of human resident cardiac stem cells by the cardiotoxic antineoplastic agent trastuzumab.
|
Stem Cells Transl Med
|
2012
|
0.89
|
|
110
|
Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore.
|
FEBS Lett
|
2002
|
0.89
|
|
111
|
Proceedings from the scientific symposium: Sex differences in cardiovascular disease and implications for therapies.
|
J Womens Health (Larchmt)
|
2010
|
0.88
|
|
112
|
Ectopic expression of KCNE3 accelerates cardiac repolarization and abbreviates the QT interval.
|
J Clin Invest
|
2002
|
0.87
|
|
113
|
Dependence of mu-conotoxin block of sodium channels on ionic strength but not on the permeating [Na+]: implications for the distinctive mechanistic interactions between Na+ and K+ channel pore-blocking toxins and their molecular targets.
|
J Biol Chem
|
2003
|
0.86
|
|
114
|
MCC-134, a single pharmacophore, opens surface ATP-sensitive potassium channels, blocks mitochondrial ATP-sensitive potassium channels, and suppresses preconditioning.
|
Circulation
|
2003
|
0.84
|
|
115
|
Selective contractile dysfunction of left, not right, ventricular myocardium in the SHHF rat.
|
Am J Physiol Heart Circ Physiol
|
2002
|
0.84
|
|
116
|
In vivo contrast free chronic myocardial infarction characterization using diffusion-weighted cardiovascular magnetic resonance.
|
J Cardiovasc Magn Reson
|
2014
|
0.84
|
|
117
|
Bone marrow-derived cell therapy after myocardial infarction--reply.
|
JAMA
|
2013
|
0.84
|
|
118
|
Long-term outcome of stem cell therapy for acute myocardial infarction: right results, wrong reasons.
|
J Am Coll Cardiol
|
2009
|
0.82
|
|
119
|
Targeted knock-down of neuronal nitric oxide synthase expression in basal forebrain with RNA interference.
|
J Neurosci Methods
|
2009
|
0.82
|
|
120
|
Moving beyond surrogate endpoints in cell therapy trials for heart disease.
|
Stem Cells Transl Med
|
2013
|
0.82
|
|
121
|
Nicorandil prevents oxidative stress-induced apoptosis in neurons by activating mitochondrial ATP-sensitive potassium channels.
|
Brain Res
|
2003
|
0.81
|
|
122
|
Structural basis of differences in isoform-specific gating and lidocaine block between cardiac and skeletal muscle sodium channels.
|
Mol Pharmacol
|
2002
|
0.81
|
|
123
|
Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV-1 release.
|
Biophys J
|
2010
|
0.80
|
|
124
|
Taking the cells out of cell therapy.
|
J Am Coll Cardiol
|
2012
|
0.79
|
|
125
|
Novel molecular determinants in the pore region of sodium channels regulate local anesthetic binding.
|
Mol Pharmacol
|
2009
|
0.79
|
|
126
|
Big cells, little cells, stem cells: agents of cardiac plasticity.
|
Circ Res
|
2007
|
0.78
|
|
127
|
Optimization of IPG strip equilibration for the basic membrane protein mABC1.
|
Proteomics
|
2005
|
0.78
|
|
128
|
A statement on ethics from the HEART Group.
|
JACC Cardiovasc Imaging
|
2008
|
0.78
|
|
129
|
Wnt signalling suppresses voltage-dependent Na⁺ channel expression in postnatal rat cardiomyocytes.
|
J Physiol
|
2015
|
0.77
|
|
130
|
Gene delivery to cardiac muscle.
|
Methods Enzymol
|
2002
|
0.76
|
|
131
|
Boot camp for mesenchymal stem cells.
|
J Am Coll Cardiol
|
2010
|
0.76
|
|
132
|
Ten good years.
|
Circ Res
|
2009
|
0.75
|
|
133
|
Training the clinician investigator.
|
Circ Res
|
2008
|
0.75
|
|
134
|
Corrigendum: Epigenomic Reprogramming of Adult Cardiomyocyte-Derived Cardiac Progenitor Cells.
|
Sci Rep
|
2017
|
0.75
|