Published in Circ Res on February 19, 2010
Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease. Cell Stem Cell (2012) 3.33
Cardiac cell therapy: where we've been, where we are, and where we should be headed. Br Med Bull (2011) 2.26
Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair. Stem Cells (2010) 2.10
Cardiac stem cell therapy and the promise of heart regeneration. Cell Stem Cell (2013) 1.86
Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair. JACC Heart Fail (2014) 1.76
Novel microRNA prosurvival cocktail for improving engraftment and function of cardiac progenitor cell transplantation. Circulation (2011) 1.48
Noninvasive monitoring of oxidative stress in transplanted mesenchymal stromal cells. JACC Cardiovasc Imaging (2013) 1.45
Targeting survival pathways to create infarct-spanning bridges of human embryonic stem cell-derived cardiomyocytes. J Thorac Cardiovasc Surg (2014) 1.44
Human Cardiac Progenitor Spheroids Exhibit Enhanced Engraftment Potential. PLoS One (2015) 1.40
Magnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusion. Cell Transplant (2012) 1.28
A naturally derived cardiac extracellular matrix enhances cardiac progenitor cell behavior in vitro. Acta Biomater (2012) 1.27
Bioengineering heart muscle: a paradigm for regenerative medicine. Annu Rev Biomed Eng (2011) 1.26
Brief report: Mechanism of extravasation of infused stem cells. Stem Cells (2012) 1.13
Coronary artery ligation and intramyocardial injection in a murine model of infarction. J Vis Exp (2011) 1.03
Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement. J Am Coll Cardiol (2014) 1.02
Breakthroughs in cell therapy for heart disease: focus on cardiosphere-derived cells. Mayo Clin Proc (2014) 1.02
Spherical bullet formation via E-cadherin promotes therapeutic potency of mesenchymal stem cells derived from human umbilical cord blood for myocardial infarction. Mol Ther (2012) 0.98
Magnetic targeting enhances retrograde cell retention in a rat model of myocardial infarction. Stem Cell Res Ther (2013) 0.98
Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles. J Am Coll Cardiol (2015) 0.95
Considerations for pre-clinical models and clinical trials of pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther (2014) 0.95
Magnet-Bead Based MicroRNA Delivery System to Modify CD133(+) Stem Cells. Stem Cells Int (2016) 0.95
Secondary sphere formation enhances the functionality of cardiac progenitor cells. Mol Ther (2012) 0.94
Tracking of stem cells in vivo for cardiovascular applications. J Cardiovasc Magn Reson (2014) 0.92
Programming and reprogramming a human heart cell. EMBO J (2015) 0.92
The effect of encapsulation of cardiac stem cells within matrix-enriched hydrogel capsules on cell survival, post-ischemic cell retention and cardiac function. Biomaterials (2013) 0.91
Injectable Hydrogels with In Situ Double Network Formation Enhance Retention of Transplanted Stem Cells. Adv Funct Mater (2015) 0.87
Prolyl hydroxylase domain protein 2 silencing enhances the survival and paracrine function of transplanted adipose-derived stem cells in infarcted myocardium. Circ Res (2013) 0.86
Endothelial progenitor cells (EPCs) as gene carrier system for rat model of human glioma. PLoS One (2012) 0.86
A multistep procedure to prepare pre-vascularized cardiac tissue constructs using adult stem sells, dynamic cell cultures, and porous scaffolds. Front Physiol (2014) 0.85
Bone marrow cell injection for chronic myocardial ischemia: the past and the future. J Cardiovasc Transl Res (2011) 0.85
Emerging roles for integrated imaging modalities in cardiovascular cell-based therapeutics: a clinical perspective. Eur J Nucl Med Mol Imaging (2011) 0.85
Delivering regenerative cues to the heart: cardiac drug delivery by microspheres and peptide nanofibers. J Cardiovasc Transl Res (2010) 0.84
Intracoronary delivery of bone-marrow-derived stem cells. Stem Cell Res Ther (2010) 0.84
Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration. Stem Cells Int (2016) 0.84
Cobalt protoporphyrin pretreatment protects human embryonic stem cell-derived cardiomyocytes from hypoxia/reoxygenation injury in vitro and increases graft size and vascularization in vivo. Stem Cells Transl Med (2014) 0.82
Strategies for tissue engineering cardiac constructs to affect functional repair following myocardial infarction. J Cardiovasc Transl Res (2011) 0.82
The modulation of cardiac progenitor cell function by hydrogel-dependent Notch1 activation. Biomaterials (2014) 0.82
Cardiac fibroblast-derived 3D extracellular matrix seeded with mesenchymal stem cells as a novel device to transfer cells to the ischemic myocardium. Cardiovasc Eng Technol (2014) 0.81
Extracellular Matrix can Recover the Downregulation of Adhesion Molecules after Cell Detachment and Enhance Endothelial Cell Engraftment. Sci Rep (2015) 0.81
Improvement of cardiac function by placenta-derived mesenchymal stem cells does not require permanent engraftment and is independent of the insulin signaling pathway. Stem Cell Res Ther (2014) 0.81
Concomitant Retrograde Coronary Venous Infusion of Basic Fibroblast Growth Factor Enhances Engraftment and Differentiation of Bone Marrow Mesenchymal Stem Cells for Cardiac Repair after Myocardial Infarction. Theranostics (2015) 0.80
Pim1 Kinase Overexpression Enhances ckit(+) Cardiac Stem Cell Cardiac Repair Following Myocardial Infarction in Swine. J Am Coll Cardiol (2016) 0.79
Intra-articular transplantation of atsttrin-transduced mesenchymal stem cells ameliorate osteoarthritis development. Stem Cells Transl Med (2015) 0.79
Cell therapies for heart function recovery: focus on myocardial tissue engineering and nanotechnologies. Cardiol Res Pract (2012) 0.78
Endogenous cardiac stem cells for the treatment of heart failure. Stem Cells Cloning (2013) 0.78
Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients. PLoS One (2014) 0.77
Matrix metalloproteinase-13 mediated degradation of hyaluronic acid-based matrices orchestrates stem cell engraftment through vascular integration. Biomaterials (2016) 0.77
Nanovector-based prolyl hydroxylase domain 2 silencing system enhances the efficiency of stem cell transplantation for infarcted myocardium repair. Int J Nanomedicine (2014) 0.77
Transplantation Effectiveness of Induced Pluripotent Stem Cells Is Improved by a Fibrinogen Biomatrix in an Experimental Model of Ischemic Heart Failure. Tissue Eng Part A (2015) 0.77
Electrical effects of stem cell transplantation for ischaemic cardiomyopathy: friend or foe? J Physiol (2016) 0.76
Cell Size Critically Determines Initial Retention of Bone Marrow Mononuclear Cells in the Heart after Intracoronary Injection: Evidence from a Rat Model. PLoS One (2016) 0.76
Microtissues in Cardiovascular Medicine: Regenerative Potential Based on a 3D Microenvironment. Stem Cells Int (2016) 0.76
Characterisation of Development and Electrophysiological Mechanisms Underlying Rhythmicity of the Avian Lymph Heart. PLoS One (2016) 0.75
Establishing Early Functional Perfusion and Structure in Tissue Engineered Cardiac Constructs. Crit Rev Biomed Eng (2015) 0.75
Increased oxygen consumption and OXPHOS potential in superhealer mesenchymal stem cells. Cell Regen (Lond) (2012) 0.75
Combinatorial extracellular matrix microenvironments promote survival and phenotype of human induced pluripotent stem cell-derived endothelial cells in hypoxia. Acta Biomater (2016) 0.75
Novel xeno-free human heart matrix-derived three-dimensional scaffolds. J Transl Med (2015) 0.75
Imaging the Biodistribution and Performance of Transplanted Stem Cells with PET. J Nucl Med (2016) 0.75
Intramyocardial cell delivery: observations in murine hearts. J Vis Exp (2014) 0.75
Membrane estrogen receptor alpha is an important modulator of bone marrow C-Kit+ cells mediated cardiac repair after myocardial infarction. Int J Clin Exp Pathol (2015) 0.75
Dendritic Polymers for Theranostics. Theranostics (2016) 0.75
Tissue Engineering Strategies for Myocardial Regeneration: Acellular Versus Cellular Scaffolds? Tissue Eng Part B Rev (2016) 0.75
Cell Therapies in Cardiomyopathy: Current Status of Clinical Trials. Anal Cell Pathol (Amst) (2017) 0.75
Non-invasive in vivo imaging of cardiac stem/progenitor cell biodistribution and retention after intracoronary and intramyocardial delivery in a swine model of chronic ischemia reperfusion injury. J Transl Med (2017) 0.75
Highly sensitive and specific Alu-based quantification of human cells among rodent cells. Sci Rep (2017) 0.75
Determining the origin of cells in tissue engineered skin substitutes: a pilot study employing in situ hybridization. Pediatr Surg Int (2011) 0.75
Cardioprotective Effects of Wharton Jelly Derived Mesenchymal Stem Cell Transplantation in a Rodent Model of Myocardial Injury. Int J Stem Cells (2017) 0.75
Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol (2007) 14.48
Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet (2004) 9.35
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation (2007) 8.62
Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nat Med (2003) 8.46
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury. Nat Med (2007) 8.06
Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell (2006) 7.21
Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med (2007) 6.68
Stem-cell therapy for cardiac disease. Nature (2008) 5.75
Regenerating the heart. Nat Biotechnol (2005) 5.58
Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation (2003) 5.20
In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation (2006) 4.48
Monitoring of bone marrow cell homing into the infarcted human myocardium. Circulation (2005) 4.20
Survival and development of neonatal rat cardiomyocytes transplanted into adult myocardium. J Mol Cell Cardiol (2002) 3.79
Radiolabeled cell distribution after intramyocardial, intracoronary, and interstitial retrograde coronary venous delivery: implications for current clinical trials. Circulation (2005) 3.61
Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation (2009) 3.45
Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J Am Coll Cardiol (2004) 3.44
A quantitative, randomized study evaluating three methods of mesenchymal stem cell delivery following myocardial infarction. Eur Heart J (2006) 3.43
Improved graft mesenchymal stem cell survival in ischemic heart with a hypoxia-regulated heme oxygenase-1 vector. J Am Coll Cardiol (2005) 3.40
Bone marrow cells differentiate in cardiac cell lineages after infarction independently of cell fusion. Circ Res (2004) 3.39
Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction. Circulation (2005) 3.33
Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol (2007) 3.05
Iron-oxide labeling and outcome of transplanted mesenchymal stem cells in the infarcted myocardium. Circulation (2007) 2.99
Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardium. Cardiovasc Res (2007) 2.98
Intra-coronary arterial injection of mesenchymal stromal cells and microinfarction in dogs. Lancet (2004) 2.96
Cardiac regeneration: repopulating the heart. Annu Rev Physiol (2006) 2.92
Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS One (2009) 2.89
Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol Ther (2006) 2.85
Clinical applications of stem cells for the heart. Circ Res (2005) 2.78
Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. Proc Natl Acad Sci U S A (2006) 2.75
Pharmacologically preconditioned skeletal myoblasts are resistant to oxidative stress and promote angiomyogenesis via release of paracrine factors in the infarcted heart. Circ Res (2007) 2.64
19F magnetic resonance imaging for stem/progenitor cell tracking with multiple unique perfluorocarbon nanobeacons. FASEB J (2007) 2.63
Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling. Circulation (2003) 2.63
Noninvasive detection of therapeutic cytolytic T cells with 18F-FHBG PET in a patient with glioma. Nat Clin Pract Oncol (2008) 2.61
Formation of human myocardium in the rat heart from human embryonic stem cells. Am J Pathol (2005) 2.60
Systems approaches to preventing transplanted cell death in cardiac repair. J Mol Cell Cardiol (2008) 2.60
Fibrin glue in coronary artery bypass grafting operations: casting out the Devil with Beelzebub? Eur J Cardiothorac Surg (2007) 2.50
Bcl-2 engineered MSCs inhibited apoptosis and improved heart function. Stem Cells (2007) 2.45
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J (2003) 2.43
Molecular imaging of cardiac cell transplantation in living animals using optical bioluminescence and positron emission tomography. Circulation (2003) 2.37
Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart. Circulation (2008) 2.37
Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography. J Am Coll Cardiol (2008) 2.33
Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. J Am Coll Cardiol (2009) 2.20
Strategies to promote donor cell survival: combining preconditioning approach with stem cell transplantation. J Mol Cell Cardiol (2008) 2.16
Attenuation correction for small animal PET tomographs. Phys Med Biol (2005) 2.16
Retroviral insertional mutagenesis: tagging cancer pathways. Adv Cancer Res (2003) 2.07
Allogeneic mesenchymal precursor cell therapy to limit remodeling after myocardial infarction: the effect of cell dosage. Ann Thorac Surg (2009) 2.06
Ex vivo cell labeling with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for imaging cell trafficking in mice with positron-emission tomography. Proc Natl Acad Sci U S A (2002) 2.01
Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium. Circulation (2008) 1.94
Over-expression of CXCR4 on mesenchymal stem cells augments myoangiogenesis in the infarcted myocardium. J Mol Cell Cardiol (2007) 1.94
Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells (2007) 1.93
Finding fluorescent needles in the cardiac haystack: tracking human mesenchymal stem cells labeled with quantum dots for quantitative in vivo three-dimensional fluorescence analysis. Stem Cells (2007) 1.84
Repair of impaired myocardium by means of implantation of engineered autologous myoblast sheets. J Thorac Cardiovasc Surg (2005) 1.82
Adult bone marrow-derived cells do not acquire functional attributes of cardiomyocytes when transplanted into peri-infarct myocardium. Mol Ther (2008) 1.75
Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts. Circulation (2006) 1.75
Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction. J Mol Cell Cardiol (2006) 1.72
Identifying and quantitating neural stem and progenitor cells in the adult brain. Methods Cell Biol (2008) 1.72
Tissue distribution of 18F-FDG-labeled peripheral hematopoietic stem cells after intracoronary administration in patients with myocardial infarction. J Nucl Med (2006) 1.72
Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice. J Clin Invest (2009) 1.69
Increasing transplanted cell survival with cell-based angiogenic gene therapy. Ann Thorac Surg (2005) 1.66
Supportive interaction between cell survival signaling and angiocompetent factors enhances donor cell survival and promotes angiomyogenesis for cardiac repair. Circ Res (2006) 1.64
Cardiogenic differentiation and transdifferentiation of progenitor cells. Circ Res (2008) 1.54
111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model. J Nucl Med (2004) 1.53
Effects of epigenetic modulation on reporter gene expression: implications for stem cell imaging. FASEB J (2005) 1.52
Washout of transplanted cells from the heart: a potential new hurdle for cell transplantation therapy. Cardiovasc Res (2005) 1.48
Dynamic tracking during intracoronary injection of 18F-FDG-labeled progenitor cell therapy for acute myocardial infarction. J Nucl Med (2007) 1.45
Massive mechanical loss of microspheres with direct intramyocardial injection in the beating heart: implications for cellular cardiomyoplasty. J Thorac Cardiovasc Surg (2006) 1.38
Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells (2004) 1.35
Stable therapeutic effects of mesenchymal stem cell-based multiple gene delivery for cardiac repair. Cardiovasc Res (2007) 1.34
Concise review: stem cells, myocardial regeneration, and methodological artifacts. Stem Cells (2006) 1.34
Human reporter genes: potential use in clinical studies. Nucl Med Biol (2007) 1.33
Role of imaging in cardiac stem cell therapy. J Am Coll Cardiol (2007) 1.32
Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Mol Imaging Biol (2008) 1.27
VEGF improves survival of mesenchymal stem cells in infarcted hearts. Biochem Biophys Res Commun (2008) 1.26
Quantitation of cell number by a positron emission tomography reporter gene strategy. Mol Imaging Biol (2004) 1.26
Optimal temporal delivery of bone marrow mesenchymal stem cells in rats with myocardial infarction. Eur J Cardiothorac Surg (2007) 1.24
Factors influencing quantification of in vivo bioluminescence imaging: application to assessment of pancreatic islet transplants. Mol Imaging (2004) 1.21
Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts. Circulation (2006) 1.20
Imaging reporter genes for cell tracking with PET and SPECT. Q J Nucl Med Mol Imaging (2005) 1.20
Safety of the use of Tissucol Duo S in cardiovascular surgery: retrospective analysis of 2149 patients after coronary artery bypass grafting. Eur J Cardiothorac Surg (2007) 1.20
Myocardial homing of nonmobilized peripheral-blood CD34+ cells after intracoronary injection. Stem Cells (2005) 1.19
CpG content affects gene silencing in mice: evidence from novel transgenes. Genome Biol (2003) 1.14
Role of interleukin-1beta in acute inflammation and graft death after cell transplantation to the heart. Circulation (2004) 1.12
Micro-positron emission tomography imaging of cardiac gene expression in rats using bicistronic adenoviral vector-mediated gene delivery. Circulation (2004) 1.10
Death and proliferation time course of stem cells transplanted in the myocardium. Mol Imaging Biol (2009) 1.08
AKT and cancer--is it all mTOR? Cancer Cell (2006) 1.08
Targeted cell delivery into infarcted rat hearts by retrograde intracoronary infusion: distribution, dynamics, and influence on cardiac function. Circulation (2004) 1.08
Heat shock treatment enhances graft cell survival in skeletal myoblast transplantation to the heart. Circulation (2000) 1.08
Epigenetic regulation of cytomegalovirus major immediate-early promoter activity in transgenic mice. Gene (2008) 1.07
Non-invasive imaging of cardiac transgene expression with PET: comparison of the human sodium/iodide symporter gene and HSV1-tk as the reporter gene. Eur J Nucl Med Mol Imaging (2005) 1.03
Optimizing gene delivery vectors for the treatment of heart disease. Expert Opin Biol Ther (2008) 1.00
Noninvasive evaluation of immunosuppressive drug efficacy on acute donor cell survival. Mol Imaging Biol (2006) 0.93
Advances in cell-based therapy for structural heart disease. Prog Cardiovasc Dis (2007) 0.91
Reporter gene PET for monitoring survival of transplanted endothelial progenitor cells in the rat heart after pretreatment with VEGF and atorvastatin. J Nucl Med (2009) 0.91
Noninvasive imaging of cell-mediated therapy for treatment of cancer. J Nucl Med (2008) 0.88
Emerging imaging techniques. Circ Res (2006) 0.86
A genetic program for deletion of foreign DNA from the mammalian genome. Mutat Res (1999) 0.85
Optimizing viral and non-viral gene transfer methods for genetic modification of porcine mesenchymal stem cells. Adv Exp Med Biol (2006) 0.84
In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts. J Heart Lung Transplant (2007) 0.83
Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet (2012) 9.86
Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation (2007) 8.62
A common genetic variant in the NOS1 regulator NOS1AP modulates cardiac repolarization. Nat Genet (2006) 6.39
Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction. Circulation (2007) 5.09
Relative roles of direct regeneration versus paracrine effects of human cardiosphere-derived cells transplanted into infarcted mice. Circ Res (2010) 4.19
Synchronized whole cell oscillations in mitochondrial metabolism triggered by a local release of reactive oxygen species in cardiac myocytes. J Biol Chem (2003) 3.93
Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol (2012) 3.48
Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation (2009) 3.45
Late gadolinium enhancement by cardiovascular magnetic resonance heralds an adverse prognosis in nonischemic cardiomyopathy. J Am Coll Cardiol (2008) 2.99
Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PLoS One (2009) 2.89
Biological pacemaker created by gene transfer. Nature (2002) 2.83
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice. J Clin Invest (2002) 2.74
Combined cardiac magnetic resonance imaging and C-reactive protein levels identify a cohort at low risk for defibrillator firings and death. Circ Cardiovasc Imaging (2012) 2.62
Genetic variations in nitric oxide synthase 1 adaptor protein are associated with sudden cardiac death in US white community-based populations. Circulation (2009) 2.55
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys J (2003) 2.52
Antiarrhythmic engineering of skeletal myoblasts for cardiac transplantation. Circ Res (2005) 2.44
Magnetic resonance imaging overestimates ferumoxide-labeled stem cell survival after transplantation in the heart. Circulation (2008) 2.37
Magnetic targeting enhances engraftment and functional benefit of iron-labeled cardiosphere-derived cells in myocardial infarction. Circ Res (2010) 2.33
Ectopic expression of the sodium-iodide symporter enables imaging of transplanted cardiac stem cells in vivo by single-photon emission computed tomography or positron emission tomography. J Am Coll Cardiol (2008) 2.33
Safety and efficacy of allogeneic cell therapy in infarcted rats transplanted with mismatched cardiosphere-derived cells. Circulation (2011) 2.29
Cardiac cell therapy: where we've been, where we are, and where we should be headed. Br Med Bull (2011) 2.26
Proteomic analysis of pharmacological preconditioning: novel protein targets converge to mitochondrial metabolism pathways. Circ Res (2006) 2.20
Noninvasive quantification and optimization of acute cell retention by in vivo positron emission tomography after intramyocardial cardiac-derived stem cell delivery. J Am Coll Cardiol (2009) 2.20
Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cells. J Physiol (2002) 2.18
Intramyocardial injection of autologous cardiospheres or cardiosphere-derived cells preserves function and minimizes adverse ventricular remodeling in pigs with heart failure post-myocardial infarction. J Am Coll Cardiol (2011) 2.15
Cardioprotection by N-acetylglucosamine linkage to cellular proteins. Circulation (2008) 2.11
Cardiospheres recapitulate a niche-like microenvironment rich in stemness and cell-matrix interactions, rationalizing their enhanced functional potency for myocardial repair. Stem Cells (2010) 2.10
Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel. Mol Cell (2004) 2.05
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. EMBO Mol Med (2013) 2.04
Uncoupling protein-2 overexpression inhibits mitochondrial death pathway in cardiomyocytes. Circ Res (2003) 1.89
Dedifferentiation and proliferation of mammalian cardiomyocytes. PLoS One (2010) 1.89
Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies. J Mol Cell Cardiol (2010) 1.88
Creation of a genetic calcium channel blocker by targeted gem gene transfer in the heart. Circ Res (2004) 1.87
Endogenous cardiac stem cells. Prog Cardiovasc Dis (2007) 1.79
Functional role of inward rectifier current in heart probed by Kir2.1 overexpression and dominant-negative suppression. J Clin Invest (2003) 1.78
Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18. Nat Biotechnol (2012) 1.74
Disproportionate enhancement of myocardial contractility by the xanthine oxidase inhibitor oxypurinol in failing rat myocardium. Cardiovasc Res (2003) 1.70
Imbalance between xanthine oxidase and nitric oxide synthase signaling pathways underlies mechanoenergetic uncoupling in the failing heart. Circ Res (2002) 1.70
A computational model integrating electrophysiology, contraction, and mitochondrial bioenergetics in the ventricular myocyte. Biophys J (2006) 1.69
CAPON modulates cardiac repolarization via neuronal nitric oxide synthase signaling in the heart. Proc Natl Acad Sci U S A (2008) 1.66
Physiological levels of reactive oxygen species are required to maintain genomic stability in stem cells. Stem Cells (2010) 1.63
Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin. Circ Res (2002) 1.62
Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity. Proc Natl Acad Sci U S A (2004) 1.60
Magnetic resonance-based anatomical analysis of scar-related ventricular tachycardia: implications for catheter ablation. Circ Res (2007) 1.58
ECG quantification of myocardial scar in cardiomyopathy patients with or without conduction defects: correlation with cardiac magnetic resonance and arrhythmogenesis. Circ Arrhythm Electrophysiol (2008) 1.55
Biological pacemaker created by percutaneous gene delivery via venous catheters in a porcine model of complete heart block. Heart Rhythm (2012) 1.54
Mixed results for bone marrow–derived cell therapy for ischemic heart disease. JAMA (2012) 1.53
Proarrhythmic potential of mesenchymal stem cell transplantation revealed in an in vitro coculture model. Circulation (2006) 1.52
Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction. Circulation (2013) 1.51
Kidney-derived stromal cells modulate dendritic and T cell responses. J Am Soc Nephrol (2009) 1.51
Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol (2002) 1.49
Expansion of human cardiac stem cells in physiological oxygen improves cell production efficiency and potency for myocardial repair. Cardiovasc Res (2010) 1.41
Pharmacological preconditioning ameliorates neurological injury in a model of spinal cord ischemia. Ann Thorac Surg (2002) 1.41
Molecular correlates of altered expression of potassium currents in failing rabbit myocardium. Am J Physiol Heart Circ Physiol (2005) 1.39
Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals. PLoS Genet (2011) 1.38
Identification and functionality of proteomes secreted by rat cardiac stem cells and neonatal cardiomyocytes. Proteomics (2010) 1.38
Human cardiospheres are a source of stem cells with cardiomyogenic potential. Stem Cells (2010) 1.33
Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers. Cardiovasc Res (2005) 1.28
Allogeneic cardiospheres safely boost cardiac function and attenuate adverse remodeling after myocardial infarction in immunologically mismatched rat strains. J Am Coll Cardiol (2013) 1.28
Magnetic enhancement of cell retention, engraftment, and functional benefit after intracoronary delivery of cardiac-derived stem cells in a rat model of ischemia/reperfusion. Cell Transplant (2012) 1.28
Mechanistically distinct steps in the mitochondrial death pathway triggered by oxidative stress in cardiac myocytes. Circ Res (2003) 1.26
Chronic treatment with allopurinol boosts survival and cardiac contractility in murine postischemic cardiomyopathy. Circ Res (2004) 1.24
Gene therapy to inhibit the calcium channel beta subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy. Circ Res (2007) 1.24
Physiological determinants of contractile force generation and calcium handling in mouse myocardium. J Mol Cell Cardiol (2002) 1.23
Biological therapies for cardiac arrhythmias: can genes and cells replace drugs and devices? Circ Res (2010) 1.21
Stem cells in the heart: what's the buzz all about? Part 2: Arrhythmic risks and clinical studies. Heart Rhythm (2008) 1.19
Is Kir6.1 a subunit of mitoK(ATP)? Biochem Biophys Res Commun (2007) 1.19
Lentiviral vector-mediated expression of GFP or Kir2.1 alters the electrophysiology of neonatal rat ventricular myocytes without inducing cytotoxicity. Am J Physiol Heart Circ Physiol (2007) 1.18
Cardioprotective role of the mitochondrial ATP-binding cassette protein 1. Circ Res (2005) 1.17
Dominant-negative suppression of HCN1- and HCN2-encoded pacemaker currents by an engineered HCN1 construct: insights into structure-function relationships and multimerization. Circ Res (2002) 1.15
Differential actions of cardioprotective agents on the mitochondrial death pathway. Circ Res (2003) 1.14
Functional performance of human cardiosphere-derived cells delivered in an in situ polymerizable hyaluronan-gelatin hydrogel. Biomaterials (2012) 1.14
Lentiviral vectors bearing the cardiac promoter of the Na+-Ca2+ exchanger report cardiogenic differentiation in stem cells. Mol Ther (2008) 1.13
Brief report: Mechanism of extravasation of infused stem cells. Stem Cells (2012) 1.13
Simvastatin attenuates oxidant-induced mitochondrial dysfunction in cardiac myocytes. Circ Res (2003) 1.12
Stem cells in the heart: what's the buzz all about?--Part 1: preclinical considerations. Heart Rhythm (2008) 1.11
Cariporide (HOE642), a selective Na+-H+ exchange inhibitor, inhibits the mitochondrial death pathway. Circulation (2003) 1.10
Nanopatterned cardiac cell patches promote stem cell niche formation and myocardial regeneration. Integr Biol (Camb) (2012) 1.08
IK1 heterogeneity affects genesis and stability of spiral waves in cardiac myocyte monolayers. Circ Res (2009) 1.07
Cellular and molecular determinants of altered Ca2+ handling in the failing rabbit heart: primary defects in SR Ca2+ uptake and release mechanisms. Am J Physiol Heart Circ Physiol (2006) 1.05
Xanthine oxidase inhibitors improve energetics and function after infarction in failing mouse hearts. Am J Physiol Heart Circ Physiol (2005) 1.04
Transcriptional suppression of connexin43 by TBX18 undermines cell-cell electrical coupling in postnatal cardiomyocytes. J Biol Chem (2011) 1.04
Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction. J Am Coll Cardiol (2008) 1.04
Myocardial substrate and route of administration determine acute cardiac retention and lung bio-distribution of cardiosphere-derived cells. J Nucl Cardiol (2011) 1.02
Antiapoptotic effect of nicorandil mediated by mitochondrial atp-sensitive potassium channels in cultured cardiac myocytes. J Am Coll Cardiol (2002) 1.02
Gene transfer of connexin43 mutants attenuates coupling in cardiomyocytes: novel basis for modulation of cardiac conduction by gene therapy. Circ Res (2007) 1.02
Spiral waves and reentry dynamics in an in vitro model of the healed infarct border zone. Circ Res (2009) 1.02
Gene transfer of a synthetic pacemaker channel into the heart: a novel strategy for biological pacing. Circulation (2006) 1.00
Transplantation of platelet gel spiked with cardiosphere-derived cells boosts structural and functional benefits relative to gel transplantation alone in rats with myocardial infarction. Biomaterials (2012) 1.00
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest (2015) 1.00
Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. Stem Cells (2014) 0.99
Creation of a biological pacemaker by cell fusion. Circ Res (2007) 0.99
Mitochondrial ATP-sensitive potassium channel activation protects cerebellar granule neurons from apoptosis induced by oxidative stress. Stroke (2003) 0.98