Published in Proc Natl Acad Sci U S A on January 31, 2012
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Diurnal Variation of Hormonal and Lipid Biomarkers in a Molecular Epidemiology-Like Setting. PLoS One (2015) 0.84
Diurnal rhythms in the human urine metabolome during sleep and total sleep deprivation. Sci Rep (2015) 0.84
Circadian variation of the human metabolome captured by real-time breath analysis. PLoS One (2014) 0.84
Stable isotope tracer analysis in isolated mitochondria from mammalian systems. Metabolites (2014) 0.83
Human breath analysis may support the existence of individual metabolic phenotypes. PLoS One (2013) 0.82
Peroxisomal localization and circadian regulation of ubiquitin-specific protease 2. PLoS One (2012) 0.82
Development of isotope labeling LC-MS for human salivary metabolomics and application to profiling metabolome changes associated with mild cognitive impairment. Anal Chem (2012) 0.82
Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation. Sleep (2014) 0.82
The proteomic landscape of the suprachiasmatic nucleus clock reveals large-scale coordination of key biological processes. PLoS Genet (2014) 0.81
Coupling circadian rhythms of metabolism and chromatin remodelling. Diabetes Obes Metab (2015) 0.81
Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses. Sci Rep (2016) 0.81
Sleep Disruption and Daytime Sleepiness Correlating with Disease Severity and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: A Comparison with Healthy Controls. PLoS One (2015) 0.80
Discovering and validating between-subject variations in plasma lipids in healthy subjects. Sci Rep (2016) 0.80
Metabolism as an integral cog in the mammalian circadian clockwork. Crit Rev Biochem Mol Biol (2013) 0.80
Lipids around the Clock: Focus on Circadian Rhythms and Lipid Metabolism. Biology (Basel) (2015) 0.80
Circadian regulation of metabolic homeostasis: causes and consequences. Nat Sci Sleep (2016) 0.79
Comparative Circadian Metabolomics Reveal Differential Effects of Nutritional Challenge in the Serum and Liver. J Biol Chem (2015) 0.79
Disruption of daily rhythms in gene expression: the importance of being synchronised. Bioessays (2014) 0.79
Insulin effects on glucose tolerance, hypermetabolic response, and circadian-metabolic protein expression in a rat burn and disuse model. Am J Physiol Regul Integr Comp Physiol (2014) 0.79
The mammalian clock and chronopharmacology. Bioorg Med Chem Lett (2013) 0.79
The hepatic circadian clock modulates xenobiotic metabolism in mice. J Biol Rhythms (2014) 0.78
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Dietary methanol regulates human gene activity. PLoS One (2014) 0.78
Glucocorticoid (dexamethasone)-induced metabolome changes in healthy males suggest prediction of response and side effects. Sci Rep (2015) 0.78
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Circadian Rhythm and Sleep Disruption: Causes, Metabolic Consequences, and Countermeasures. Endocr Rev (2016) 0.78
Circadian redox and metabolic oscillations in mammalian systems. Antioxid Redox Signal (2013) 0.77
Salivary biomarkers of physical fatigue as markers of sleep deprivation. J Clin Sleep Med (2013) 0.77
Altered dynamics in the circadian oscillation of clock genes in dermal fibroblasts of patients suffering from idiopathic hypersomnia. PLoS One (2014) 0.77
Circadian Rhythms, Metabolism, and Chrononutrition in Rodents and Humans. Adv Nutr (2016) 0.77
Clock Regulation of Metabolites Reveals Coupling between Transcription and Metabolism. Cell Metab (2017) 0.76
Is the timing of caloric intake associated with variation in diet-induced thermogenesis and in the metabolic pattern? A randomized cross-over study. Int J Obes (Lond) (2015) 0.76
The Liver Clock Controls Cholesterol Homeostasis through Trib1 Protein-mediated Regulation of PCSK9/Low Density Lipoprotein Receptor (LDLR) Axis. J Biol Chem (2015) 0.76
Aging alters circadian regulation of redox in Drosophila. Front Genet (2015) 0.76
Cancer Clocks Out for Lunch: Disruption of Circadian Rhythm and Metabolic Oscillation in Cancer. Front Cell Dev Biol (2016) 0.76
Cross-talk between circadian clocks, sleep-wake cycles, and metabolic networks: Dispelling the darkness. Bioessays (2016) 0.76
Plasma Metabolomic Changes following PI3K Inhibition as Pharmacodynamic Biomarkers: Preclinical Discovery to Phase I Trial Evaluation. Mol Cancer Ther (2016) 0.76
The impact of free or standardized lifestyle and urine sampling protocol on metabolome recognition accuracy. Genes Nutr (2014) 0.76
The Karlsruhe Metabolomics and Nutrition (KarMeN) Study: Protocol and Methods of a Cross-Sectional Study to Characterize the Metabolome of Healthy Men and Women. JMIR Res Protoc (2016) 0.76
The molecular basis of metabolic cycles and their relationship to circadian rhythms. Nat Struct Mol Biol (2016) 0.75
FAD Regulates CRYPTOCHROME Protein Stability and Circadian Clock in Mice. Cell Rep (2017) 0.75
Extensive Regulation of Diurnal Transcription and Metabolism by Glucocorticoids. PLoS Genet (2016) 0.75
Biological Rhythms in the Skin. Int J Mol Sci (2016) 0.75
The Swine Plasma Metabolome Chronicles "Many Days" Biological Timing and Functions Linked to Growth. PLoS One (2016) 0.75
Mining for novel candidate clock genes in the circadian regulatory network. BMC Syst Biol (2015) 0.75
Amyloid-β-Induced Changes in Molecular Clock Properties and Cellular Bioenergetics. Front Neurosci (2017) 0.75
Time is ripe: maturation of metabolomics in chronobiology. Curr Opin Biotechnol (2016) 0.75
Principles for circadian orchestration of metabolic pathways. Proc Natl Acad Sci U S A (2017) 0.75
Circadian Clocks and the Interaction between Stress Axis and Adipose Function. Int J Endocrinol (2015) 0.75
Theory of Inpatient Circadian Care (TICC): A Proposal for a Middle-Range Theory. Open Nurs J (2015) 0.75
Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism. Genet Test Mol Biomarkers (2016) 0.75
Systems Biology-Derived Discoveries of Intrinsic Clocks. Front Neurol (2017) 0.75
Transcriptional control of circadian metabolic rhythms in the liver. Diabetes Obes Metab (2015) 0.75
Glutathione species and metabolomic prints in subjects with liver disease as biological markers for the detection of hepatocellular carcinoma. HPB (Oxford) (2016) 0.75
Coordinated transcription of key pathways in the mouse by the circadian clock. Cell (2002) 14.07
Obesity and metabolic syndrome in circadian Clock mutant mice. Science (2005) 12.66
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
Extensive and divergent circadian gene expression in liver and heart. Nature (2002) 9.64
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Analysis of the adult human plasma metabolome. Pharmacogenomics (2008) 3.74
Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring) (2009) 3.44
JTK_CYCLE: an efficient nonparametric algorithm for detecting rhythmic components in genome-scale data sets. J Biol Rhythms (2010) 3.42
Circadian orchestration of the hepatic proteome. Curr Biol (2006) 3.37
Crosstalk between components of circadian and metabolic cycles in mammals. Cell Metab (2011) 3.31
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Peripheral circadian oscillators in mammals: time and food. J Biol Rhythms (2003) 3.10
Rhythms of mammalian body temperature can sustain peripheral circadian clocks. Curr Biol (2002) 3.05
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proc Natl Acad Sci U S A (2009) 2.98
alpha-hydroxybutyrate is an early biomarker of insulin resistance and glucose intolerance in a nondiabetic population. PLoS One (2010) 2.94
Circadian rhythms, sleep, and metabolism. J Clin Invest (2011) 2.60
Diagnostic potential of saliva: current state and future applications. Clin Chem (2011) 2.20
Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Anal Chem (2007) 2.15
Homer1a is a core brain molecular correlate of sleep loss. Proc Natl Acad Sci U S A (2007) 2.13
Getting through to circadian oscillators: why use constant routines? J Biol Rhythms (2002) 2.02
Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer. Nat Rev Clin Oncol (2011) 1.69
Diurnal variation in glutathione and cysteine redox states in human plasma. Am J Clin Nutr (2007) 1.66
Measurement of internal body time by blood metabolomics. Proc Natl Acad Sci U S A (2009) 1.56
Understanding the human salivary metabolome. NMR Biomed (2009) 1.55
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Deficiency in short-chain fatty acid beta-oxidation affects theta oscillations during sleep. Nat Genet (2003) 1.45
Circadian rhythms in cognitive performance: methodological constraints, protocols, theoretical underpinnings. Physiol Behav (2006) 1.43
Sleep and the metabolic syndrome. Exp Physiol (2006) 1.43
Urine metabolite analysis offers potential early diagnosis of ovarian and breast cancers. Clin Cancer Res (2010) 1.42
Permutation test for periodicity in short time series data. BMC Bioinformatics (2006) 1.18
Twenty-four-hour plasma tryptophan concentrations and ratios are below normal in obese subjects and are not normalized by substantial weight reduction. Am J Clin Nutr (2003) 1.05
Effects of sleep and sleep deprivation on immunoglobulins and complement in humans. Brain Behav Immun (2006) 1.04
Regulation of fatty acid metabolism by cell autonomous circadian clocks: time to fatten up on information? J Biol Chem (2011) 1.01
Blunted metabolic response to fasting in obese mice. Endocrine (2007) 0.96
Potential of human saliva for nuclear magnetic resonance-based metabolomics and for health-related biomarker identification. Anal Chem (2009) 0.91
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A phase response curve to single bright light pulses in human subjects. J Physiol (2003) 3.29
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Sleep-wake cycles and cognitive functioning in schizophrenia. Br J Psychiatry (2011) 1.76
Encoding difficulty promotes postlearning changes in sleep spindle activity during napping. J Neurosci (2006) 1.73
A time to think: circadian rhythms in human cognition. Cogn Neuropsychol (2007) 1.62
Low-dose repeated caffeine administration for circadian-phase-dependent performance degradation during extended wakefulness. Sleep (2004) 1.54
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Non-visual effects of light on melatonin, alertness and cognitive performance: can blue-enriched light keep us alert? PLoS One (2011) 1.49
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Circadian and wake-dependent modulation of fastest and slowest reaction times during the psychomotor vigilance task. Physiol Behav (2004) 1.43
Early morning executive functioning during sleep deprivation is compromised by a PERIOD3 polymorphism. Sleep (2008) 1.43
NONO couples the circadian clock to the cell cycle. Proc Natl Acad Sci U S A (2012) 1.34
Homeostatic sleep pressure and responses to sustained attention in the suprachiasmatic area. Science (2009) 1.30
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Wavelength-dependent effects of evening light exposure on sleep architecture and sleep EEG power density in men. Am J Physiol Regul Integr Comp Physiol (2006) 1.14
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Subjective well-being is modulated by circadian phase, sleep pressure, age, and gender. J Biol Rhythms (2009) 1.08
Age-related changes in cardiac autonomic control during sleep. J Sleep Res (2003) 1.07
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Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3. J Clin Endocrinol Metab (2011) 1.06
The physiological period length of the human circadian clock in vivo is directly proportional to period in human fibroblasts. PLoS One (2010) 1.05
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Distinct roles of DBHS family members in the circadian transcriptional feedback loop. Mol Cell Biol (2012) 0.99
Circadian preference modulates the neural substrate of conflict processing across the day. PLoS One (2012) 0.98
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Acute exposure to evening blue-enriched light impacts on human sleep. J Sleep Res (2013) 0.92
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Regional differences in the circadian modulation of human sleep spindle characteristics. Eur J Neurosci (2003) 0.88
Thermoregulatory effects of melatonin in relation to sleepiness. Chronobiol Int (2006) 0.88
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Age-related changes in the circadian modulation of sleep-spindle frequency during nap sleep. Sleep (2005) 0.87
Evening melatonin and bright light administration induce additive phase shifts in dim light melatonin onset. J Pineal Res (2004) 0.87
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The hockey-stick method to estimate evening dim light melatonin onset (DLMO) in humans. Chronobiol Int (2013) 0.86
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Young women with major depression live on higher homeostatic sleep pressure than healthy controls. Chronobiol Int (2012) 0.85
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Age-dependent alterations in human PER2 levels after early morning blue light exposure. Chronobiol Int (2009) 0.83
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Cortical activation patterns herald successful dream recall after NREM and REM sleep. Biol Psychol (2011) 0.83
Thermophysiologic aspects of the three-process-model of sleepiness regulation. Clin Sports Med (2005) 0.83
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Sleep loss-related decrements in planning performance in healthy elderly depend on task difficulty. J Sleep Res (2005) 0.82
An improved method for estimating human circadian phase derived from multichannel ambulatory monitoring and artificial neural networks. Chronobiol Int (2012) 0.82
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Genetic polymorphisms of DAT1 and COMT differentially associate with actigraphy-derived sleep-wake cycles in young adults. Chronobiol Int (2014) 0.80
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Does the circadian modulation of dream recall modify with age? Sleep (2009) 0.79
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Regional differences in trait-like characteristics of the waking EEG in early adolescence. BMC Neurosci (2013) 0.79
Daytime sleepiness in renal transplant recipients is associated with immunosuppressive non-adherence: a cross-sectional, multi-center study. Clin Transplant (2013) 0.79
Sleep respiratory disturbances and arousals at moderate altitude have overlapping electroencephalogram spectral signatures. J Sleep Res (2014) 0.78
Validation of a single item to assess daytime sleepiness for the Swiss Transplant Cohort Study. Prog Transplant (2013) 0.78
Extraocular light via the ear canal does not acutely affect human circadian physiology, alertness and psychomotor vigilance performance. Chronobiol Int (2013) 0.78
Impact of age, sleep pressure and circadian phase on time-of-day estimates. Behav Brain Res (2009) 0.78
Circadian sleep-wake cycles, well-being, and light therapy in borderline personality disorder. J Pers Disord (2012) 0.78
Adapting test timing to the sleep-wake schedule: effects on diurnal neurobehavioral performance changes in young evening and older morning chronotypes. Chronobiol Int (2012) 0.77
Self-reported sleep disturbances in renal transplant recipients. BMC Nephrol (2013) 0.77
Developmental changes in sleep biology and potential effects on adolescent behavior and caffeine use. Nutr Rev (2014) 0.77
The effect of bright light therapy on sleep and circadian rhythms in renal transplant recipients: a pilot randomized, multicentre wait-list controlled trial. Transpl Int (2014) 0.77
Age effects on spectral electroencephalogram activity prior to dream recall. J Sleep Res (2011) 0.76
Ultradian and circadian modulation of dream recall: EEG correlates and age effects. Int J Psychophysiol (2013) 0.76
L-arginine: an ultradian-regulated substrate coupled with insulin oscillations in healthy volunteers. Diabetes Care (2003) 0.76
Web-Based Assessment of Mental Well-Being in Early Adolescence: A Reliability Study. J Med Internet Res (2016) 0.75
The tick-tock of language: is language processing sensitive to circadian rhythmicity and elevated sleep pressure? Chronobiol Int (2009) 0.75
The circadian rest-activity cycle in Korsakoff psychosis. Am J Geriatr Psychiatry (2010) 0.75
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