Published in J Am Chem Soc on February 22, 2012
High-pressure NMR reveals close similarity between cold and alcohol protein denaturation in ubiquitin. Proc Natl Acad Sci U S A (2013) 0.92
Cooperative unfolding of compact conformations of the intrinsically disordered protein osteopontin. Biochemistry (2013) 0.92
Quantitative assessments of the distinct contributions of polypeptide backbone amides versus side chain groups to chain expansion via chemical denaturation. J Am Chem Soc (2015) 0.83
Toward an atomistic description of the urea-denatured state of proteins. Proc Natl Acad Sci U S A (2013) 0.83
Biophysical properties of intrinsically disordered p130Cas substrate domain--implication in mechanosensing. PLoS Comput Biol (2014) 0.80
The dynamic duo: combining NMR and small angle scattering in structural biology. Protein Sci (2014) 0.79
X-ray scattering experiments with high-flux X-ray source coupled rapid mixing microchannel device and their potential for high-flux neutron scattering investigations. Eur Phys J E Soft Matter (2013) 0.78
NMR characterization of the near native and unfolded states of the PTB domain of Dok1: alternate conformations and residual clusters. PLoS One (2014) 0.78
Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS. Proc Natl Acad Sci U S A (2016) 0.77
Dispersion interactions between urea and nucleobases contribute to the destabilization of RNA by urea in aqueous solution. J Phys Chem B (2015) 0.75
Structural characterization of flexible proteins using small-angle X-ray scattering. J Am Chem Soc (2007) 6.53
Targeting Bcr-Abl by combining allosteric with ATP-binding-site inhibitors. Nature (2010) 3.39
DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus. Proc Natl Acad Sci U S A (2007) 2.42
Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings. Proc Natl Acad Sci U S A (2005) 2.35
A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 2.28
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. Proc Natl Acad Sci U S A (2008) 2.14
Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib. J Biol Chem (2008) 2.09
Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy. J Am Chem Soc (2007) 2.04
Continuous molecular evolution of protein-domain structures by single amino acid changes. Curr Biol (2007) 1.81
Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75
Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. EMBO J (2004) 1.69
Toward a unified representation of protein structural dynamics in solution. J Am Chem Soc (2009) 1.55
The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. J Biol Chem (2005) 1.49
Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49
A thermodynamic switch modulates abscisic acid receptor sensitivity. EMBO J (2011) 1.44
NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43
Calcium-dependent homoassociation of E-cadherin by NMR spectroscopy: changes in mobility, conformation and mapping of contact regions. J Mol Biol (2002) 1.40
Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angew Chem Int Ed Engl (2009) 1.38
Recognition of RANTES by extracellular parts of the CCR5 receptor. J Mol Biol (2006) 1.35
The structure of the box C/D enzyme reveals regulation of RNA methylation. Nature (2013) 1.34
Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33
Oligomer formation of the bacterial second messenger c-di-GMP: reaction rates and equilibrium constants indicate a monomeric state at physiological concentrations. J Am Chem Soc (2011) 1.28
Intrinsic disorder in measles virus nucleocapsids. Proc Natl Acad Sci U S A (2011) 1.27
Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings. J Am Chem Soc (2009) 1.24
Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables. Bioinformatics (2012) 1.22
Describing intrinsically disordered proteins at atomic resolution by NMR. Curr Opin Struct Biol (2013) 1.22
Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings. J Am Chem Soc (2006) 1.22
Domain conformation of tau protein studied by solution small-angle X-ray scattering. Biochemistry (2008) 1.20
Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20
Temperature-dependence of protein hydrogen bond properties as studied by high-resolution NMR. J Mol Biol (2002) 1.19
Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19
Enhanced conformational space sampling improves the prediction of chemical shifts in proteins. J Am Chem Soc (2010) 1.18
Very fast folding and association of a trimerization domain from bacteriophage T4 fibritin. J Mol Biol (2004) 1.18
Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18
Structural biology: Proteins in dynamic equilibrium. Nature (2010) 1.16
Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: application to the molecular recognition element of Sendai virus nucleoprotein. J Am Chem Soc (2008) 1.15
Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts. J Am Chem Soc (2010) 1.15
Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings. J Am Chem Soc (2004) 1.14
The solution structure and DNA-binding properties of the cold-shock domain of the human Y-box protein YB-1. J Mol Biol (2002) 1.14
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13
Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12
Solution structure of the PilZ domain protein PA4608 complex with cyclic di-GMP identifies charge clustering as molecular readout. J Biol Chem (2011) 1.11
Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein. J Mol Recognit (2010) 1.10
Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein. J Mol Biol (2008) 1.10
Site-specific measurement of slow motions in proteins. J Am Chem Soc (2011) 1.10
In support of the BMRB. Nat Struct Mol Biol (2012) 1.09
Structure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFb. Proc Natl Acad Sci U S A (2007) 1.09
Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chem Rev (2014) 1.08
Minicollagen-15, a novel minicollagen isolated from Hydra, forms tubule structures in nematocysts. J Mol Biol (2007) 1.08
Key stabilizing elements of protein structure identified through pressure and temperature perturbation of its hydrogen bond network. Nat Chem (2012) 1.07
Conformational distributions of unfolded polypeptides from novel NMR techniques. J Chem Phys (2008) 1.06
Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution. Virology (2004) 1.06
Neutron scattering reveals extremely slow cell water in a Dead Sea organism. Proc Natl Acad Sci U S A (2007) 1.04
Direct observation of Calpha-Halpha...O=C hydrogen bonds in proteins by interresidue h3JCalphaC' scalar couplings. J Am Chem Soc (2003) 1.04
NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors. Proc Natl Acad Sci U S A (2013) 1.03
Ensemble calculations of unstructured proteins constrained by RDC and PRE data: a case study of urea-denatured ubiquitin. J Am Chem Soc (2010) 1.03
Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. Chembiochem (2012) 1.03
Testing the validity of ensemble descriptions of intrinsically disordered proteins. Proc Natl Acad Sci U S A (2014) 1.02
Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings. J Am Chem Soc (2010) 1.02
DOTA-M8: An extremely rigid, high-affinity lanthanide chelating tag for PCS NMR spectroscopy. J Am Chem Soc (2009) 1.02
Simultaneous definition of high resolution protein structure and backbone conformational dynamics using NMR residual dipolar couplings. Chemphyschem (2007) 1.02
ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble. BMC Bioinformatics (2009) 1.01
Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles. Biophys J (2006) 1.00
Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr. J Mol Biol (2002) 0.99
Structural analysis of B-Box 2 from MuRF1: identification of a novel self-association pattern in a RING-like fold. Biochemistry (2008) 0.99
Structural dynamics of protein backbone phi angles: extended molecular dynamics simulations versus experimental (3) J scalar couplings. J Biomol NMR (2009) 0.98
Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy. Mol Biosyst (2011) 0.98
Anisotropic collective motion contributes to nuclear spin relaxation in crystalline proteins. J Am Chem Soc (2010) 0.98
Direct detection of N-H[...]N hydrogen bonds in biomolecules by NMR spectroscopy. Nat Protoc (2008) 0.97
Visualizing the molecular recognition trajectory of an intrinsically disordered protein using multinuclear relaxation dispersion NMR. J Am Chem Soc (2015) 0.97
Direct observation of dipolar couplings and hydrogen bonds across a beta-hairpin in 8 M urea. J Am Chem Soc (2007) 0.96
Nuclear magnetic resonance provides a quantitative description of protein conformational flexibility on physiologically important time scales. Biochemistry (2011) 0.96
Central domain of DivIB caps the C-terminal regions of the FtsL/DivIC coiled-coil rod. J Biol Chem (2009) 0.95
Site-specific backbone dynamics from a crystalline protein by solid-state NMR spectroscopy. J Am Chem Soc (2004) 0.95
Probing electric fields in proteins in solution by NMR spectroscopy. Proteins (2008) 0.95
Relaxation-based structure refinement and backbone molecular dynamics of the dynein motor domain-associated light chain. Biochemistry (2003) 0.94
Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. J Am Chem Soc (2007) 0.94
Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. J Am Chem Soc (2011) 0.94
The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices. Protein Sci (2011) 0.93
Local dynamic amplitudes on the protein backbone from dipolar couplings: toward the elucidation of slower motions in biomolecules. J Am Chem Soc (2004) 0.93
Observation of heteronuclear overhauser effects confirms the 15N-1H dipolar relaxation mechanism in a crystalline protein. J Am Chem Soc (2006) 0.93
Quantitative analysis of backbone dynamics in a crystalline protein from nitrogen-15 spin-lattice relaxation. J Am Chem Soc (2005) 0.93
Conformational propensities of intrinsically disordered proteins from NMR chemical shifts. Chemphyschem (2013) 0.92