Conformational propensities of intrinsically disordered proteins from NMR chemical shifts.

Free-energy landscape of protein oligomerization from atomistic simulations. Proc Natl Acad Sci U S A (2013) 0.90

NMR contributions to structural dynamics studies of intrinsically disordered proteins. J Magn Reson (2014) 0.89

A maximum entropy approach to the study of residue-specific backbone angle distributions in α-synuclein, an intrinsically disordered protein. Protein Sci (2014) 0.88

The C-terminal threonine of Aβ43 nucleates toxic aggregation via structural and dynamical changes in monomers and protofibrils. Biochemistry (2014) 0.84

Identification of Atg3 as an intrinsically disordered polypeptide yields insights into the molecular dynamics of autophagy-related proteins in yeast. Autophagy (2014) 0.82

A reduced dimensionality NMR pulse sequence and an efficient protocol for unambiguous assignment in intrinsically disordered proteins. J Biomol NMR (2014) 0.78

There is Diversity in Disorder-"In all Chaos there is a Cosmos, in all Disorder a Secret Order". Front Mol Biosci (2016) 0.76

Hyperphosphorylation of intrinsically disordered tau protein induces an amyloidogenic shift in its conformational ensemble. PLoS One (2015) 0.76

Insights into Unfolded Proteins from the Intrinsic ϕ/ψ Propensities of the AAXAA Host-Guest Series. Biophys J (2016) 0.76

Quantitative evaluation of positive ϕ angle propensity in flexible regions of proteins from three-bond J couplings. Phys Chem Chem Phys (2016) 0.76

Dihedral angle preferences of amino acid residues forming various non-local interactions in proteins. J Biol Phys (2017) 0.75

Biophysical characterization of the structural change of Nopp140, an intrinsically disordered protein, in the interaction with CK2α. Biochem Biophys Res Commun (2016) 0.75

Structural characterization of flexible proteins using small-angle X-ray scattering. J Am Chem Soc (2007) 6.53

Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings. Proc Natl Acad Sci U S A (2005) 2.35

A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 2.28

Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domain. Proc Natl Acad Sci U S A (2008) 2.14

Exploring multiple timescale motions in protein GB3 using accelerated molecular dynamics and NMR spectroscopy. J Am Chem Soc (2007) 2.04

Defining long-range order and local disorder in native alpha-synuclein using residual dipolar couplings. J Am Chem Soc (2005) 1.75

Toward a unified representation of protein structural dynamics in solution. J Am Chem Soc (2009) 1.55

Highly populated turn conformations in natively unfolded tau protein identified from residual dipolar couplings and molecular simulation. J Am Chem Soc (2007) 1.49

A thermodynamic switch modulates abscisic acid receptor sensitivity. EMBO J (2011) 1.44

NMR characterization of long-range order in intrinsically disordered proteins. J Am Chem Soc (2010) 1.43

Protein conformational flexibility from structure-free analysis of NMR dipolar couplings: quantitative and absolute determination of backbone motion in ubiquitin. Angew Chem Int Ed Engl (2009) 1.38

Quantitative determination of the conformational properties of partially folded and intrinsically disordered proteins using NMR dipolar couplings. Structure (2009) 1.33

Intrinsic disorder in measles virus nucleocapsids. Proc Natl Acad Sci U S A (2011) 1.27

Quantitative description of backbone conformational sampling of unfolded proteins at amino acid resolution from NMR residual dipolar couplings. J Am Chem Soc (2009) 1.24

Flexible-meccano: a tool for the generation of explicit ensemble descriptions of intrinsically disordered proteins and their associated experimental observables. Bioinformatics (2012) 1.22

Describing intrinsically disordered proteins at atomic resolution by NMR. Curr Opin Struct Biol (2013) 1.22

Simultaneous determination of protein backbone structure and dynamics from residual dipolar couplings. J Am Chem Soc (2006) 1.22

Domain conformation of tau protein studied by solution small-angle X-ray scattering. Biochemistry (2008) 1.20

Structure of the vesicular stomatitis virus N⁰-P complex. PLoS Pathog (2011) 1.20

Mapping the potential energy landscape of intrinsically disordered proteins at amino acid resolution. J Am Chem Soc (2012) 1.19

Enhanced conformational space sampling improves the prediction of chemical shifts in proteins. J Am Chem Soc (2010) 1.18

Structural characterization of alpha-synuclein in an aggregation prone state. Protein Sci (2009) 1.18

Structural biology: Proteins in dynamic equilibrium. Nature (2010) 1.16

Defining conformational ensembles of intrinsically disordered and partially folded proteins directly from chemical shifts. J Am Chem Soc (2010) 1.15

Quantitative conformational analysis of partially folded proteins from residual dipolar couplings: application to the molecular recognition element of Sendai virus nucleoprotein. J Am Chem Soc (2008) 1.15

Anisotropic small amplitude Peptide plane dynamics in proteins from residual dipolar couplings. J Am Chem Soc (2004) 1.14

pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Res (2013) 1.13

Conformational changes specific for pseudophosphorylation at serine 262 selectively impair binding of tau to microtubules. Biochemistry (2009) 1.12

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein. J Mol Recognit (2010) 1.10

Solution structure of the C-terminal nucleoprotein-RNA binding domain of the vesicular stomatitis virus phosphoprotein. J Mol Biol (2008) 1.10

Site-specific measurement of slow motions in proteins. J Am Chem Soc (2011) 1.10

Exploring free-energy landscapes of intrinsically disordered proteins at atomic resolution using NMR spectroscopy. Chem Rev (2014) 1.08

Conformational distributions of unfolded polypeptides from novel NMR techniques. J Chem Phys (2008) 1.06

Structure and dynamics of the nucleocapsid-binding domain of the Sendai virus phosphoprotein in solution. Virology (2004) 1.06

Intrinsically disordered proteins: from sequence and conformational properties toward drug discovery. Chembiochem (2012) 1.03

Testing the validity of ensemble descriptions of intrinsically disordered proteins. Proc Natl Acad Sci U S A (2014) 1.02

Side-chain chi(1) conformations in urea-denatured ubiquitin and protein G from (3)J coupling constants and residual dipolar couplings. J Am Chem Soc (2010) 1.02

Simultaneous definition of high resolution protein structure and backbone conformational dynamics using NMR residual dipolar couplings. Chemphyschem (2007) 1.02

ProtSA: a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble. BMC Bioinformatics (2009) 1.01

Sequence-specific solvent accessibilities of protein residues in unfolded protein ensembles. Biophys J (2006) 1.00

Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr. J Mol Biol (2002) 0.99

Structural dynamics of protein backbone phi angles: extended molecular dynamics simulations versus experimental (3) J scalar couplings. J Biomol NMR (2009) 0.98

Towards a robust description of intrinsic protein disorder using nuclear magnetic resonance spectroscopy. Mol Biosyst (2011) 0.98

Anisotropic collective motion contributes to nuclear spin relaxation in crystalline proteins. J Am Chem Soc (2010) 0.98

Visualizing the molecular recognition trajectory of an intrinsically disordered protein using multinuclear relaxation dispersion NMR. J Am Chem Soc (2015) 0.97

Direct observation of dipolar couplings and hydrogen bonds across a beta-hairpin in 8 M urea. J Am Chem Soc (2007) 0.96

Nuclear magnetic resonance provides a quantitative description of protein conformational flexibility on physiologically important time scales. Biochemistry (2011) 0.96

Site-specific backbone dynamics from a crystalline protein by solid-state NMR spectroscopy. J Am Chem Soc (2004) 0.95

Probing electric fields in proteins in solution by NMR spectroscopy. Proteins (2008) 0.95

Relaxation-based structure refinement and backbone molecular dynamics of the dynein motor domain-associated light chain. Biochemistry (2003) 0.94

Amino acid bulkiness defines the local conformations and dynamics of natively unfolded alpha-synuclein and tau. J Am Chem Soc (2007) 0.94

Structural impact of proline-directed pseudophosphorylation at AT8, AT100, and PHF1 epitopes on 441-residue tau. J Am Chem Soc (2011) 0.94

Local dynamic amplitudes on the protein backbone from dipolar couplings: toward the elucidation of slower motions in biomolecules. J Am Chem Soc (2004) 0.93

Observation of heteronuclear overhauser effects confirms the 15N-1H dipolar relaxation mechanism in a crystalline protein. J Am Chem Soc (2006) 0.93

Quantitative analysis of backbone dynamics in a crystalline protein from nitrogen-15 spin-lattice relaxation. J Am Chem Soc (2005) 0.93

The N(0)-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices. Protein Sci (2011) 0.93

Accurate characterization of weak macromolecular interactions by titration of NMR residual dipolar couplings: application to the CD2AP SH3-C:ubiquitin complex. Nucleic Acids Res (2009) 0.92

Transient electrostatic interactions dominate the conformational equilibrium sampled by multidomain splicing factor U2AF65: a combined NMR and SAXS study. J Am Chem Soc (2014) 0.92

Structure of the tetramerization domain of measles virus phosphoprotein. J Virol (2013) 0.92

Measurement of site-specific 13C spin-lattice relaxation in a crystalline protein. J Am Chem Soc (2010) 0.91

A self-consistent description of the conformational behavior of chemically denatured proteins from NMR and small angle scattering. Biophys J (2009) 0.89

Mapping the population of protein conformational energy sub-states from NMR dipolar couplings. Angew Chem Int Ed Engl (2013) 0.89

Pilotin-secretin recognition in the type II secretion system of Klebsiella oxytoca. Mol Microbiol (2011) 0.87

Mapping the conformational landscape of urea-denatured ubiquitin using residual dipolar couplings. J Am Chem Soc (2007) 0.87

Sequence-specific mapping of the interaction between urea and unfolded ubiquitin from ensemble analysis of NMR and small angle scattering data. J Am Chem Soc (2012) 0.87

Toxicity of CdTe quantum dots in bacterial strains. IEEE Trans Nanobioscience (2009) 0.87

Phosphorylation of human Tau protein by microtubule affinity-regulating kinase 2. Biochemistry (2013) 0.87

16-fold degeneracy of peptide plane orientations from residual dipolar couplings: analytical treatment and implications for protein structure determination. J Am Chem Soc (2008) 0.86

Intrinsic dynamics of the partly unstructured PX domain from the Sendai virus RNA polymerase cofactor P. Biophys J (2007) 0.85

Structure, dynamics, and kinetics of weak protein-protein complexes from NMR spin relaxation measurements of titrated solutions. Angew Chem Int Ed Engl (2011) 0.84

Multi-timescale conformational dynamics of the SH3 domain of CD2-associated protein using NMR spectroscopy and accelerated molecular dynamics. Angew Chem Int Ed Engl (2012) 0.84

Solution structure, dynamics and thermodynamics of the three SH3 domains of CD2AP. J Biomol NMR (2011) 0.84

Solution structure of the sulfite reductase flavodoxin-like domain from Escherichia coli. Biochemistry (2005) 0.84

Protein backbone dynamics from N-HN dipolar couplings in partially aligned systems: a comparison of motional models in the presence of structural noise. J Magn Reson (2005) 0.83

Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus. PLoS Pathog (2013) 0.83

The influence of nitrogen-15 proton-driven spin diffusion on the measurement of nitrogen-15 longitudinal relaxation times. J Magn Reson (2006) 0.82

Long-range correlated dynamics in intrinsically disordered proteins. J Am Chem Soc (2014) 0.82

Specific and nonspecific interactions in ultraweak protein-protein associations revealed by solvent paramagnetic relaxation enhancements. J Am Chem Soc (2014) 0.82

Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus. J Biol Chem (2011) 0.82