Published in EMBO Rep on April 01, 2012
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Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J Cell Biol (2014) 2.95
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J (2014) 2.93
The roles of PINK1, parkin, and mitochondrial fidelity in Parkinson's disease. Neuron (2015) 2.82
PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria. Nat Commun (2012) 2.55
The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ (2012) 2.45
Mitochondria and mitophagy: the yin and yang of cell death control. Circ Res (2012) 2.38
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J (2012) 2.36
Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism. Cold Spring Harb Perspect Biol (2012) 2.10
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding. J Cell Biol (2013) 2.04
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia. Cancer Cell (2015) 1.70
PINK1 is degraded through the N-end rule pathway. Autophagy (2013) 1.63
A new pathway for mitochondrial quality control: mitochondrial-derived vesicles. EMBO J (2014) 1.55
Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation. J Biol Chem (2013) 1.50
Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy. J Biol Chem (2012) 1.33
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria. Autophagy (2013) 1.31
Organellophagy: eliminating cellular building blocks via selective autophagy. J Cell Biol (2014) 1.25
USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. EMBO J (2014) 1.20
After the banquet: mitochondrial biogenesis, mitophagy, and cell survival. Autophagy (2013) 1.17
Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? Front Neurol (2013) 1.17
Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase A. J Neurochem (2013) 1.16
Mitochondrial quality control and communications with the nucleus are important in maintaining mitochondrial function and cell health. Biochim Biophys Acta (2013) 1.10
A dimeric PINK1-containing complex on depolarized mitochondria stimulates Parkin recruitment. J Biol Chem (2013) 1.08
The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Genes Dev (2015) 1.08
Molecular mechanisms of mitochondrial autophagy/mitophagy in the heart. Circ Res (2015) 1.06
Pink1 kinase and its membrane potential (Deltaψ)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode. J Biol Chem (2012) 1.06
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently. J Cell Sci (2014) 1.04
PINK1 protects against cell death induced by mitochondrial depolarization, by phosphorylating Bcl-xL and impairing its pro-apoptotic cleavage. Cell Death Differ (2013) 1.04
Mitochondrial dysfunction and mitophagy: the beginning and end to diabetic nephropathy? Br J Pharmacol (2014) 1.02
MitoFates: improved prediction of mitochondrial targeting sequences and their cleavage sites. Mol Cell Proteomics (2015) 1.00
α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease. Free Radic Biol Med (2013) 0.99
Structure and Function of Parkin, PINK1, and DJ-1, the Three Musketeers of Neuroprotection. Front Neurol (2013) 0.99
A mitocentric view of Parkinson's disease. Annu Rev Neurosci (2014) 0.99
Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy. EMBO Rep (2013) 0.98
How mitochondrial dynamism orchestrates mitophagy. Circ Res (2015) 0.98
A Ubl/ubiquitin switch in the activation of Parkin. EMBO J (2015) 0.96
Mitophagy in neurodegeneration and aging. Front Genet (2012) 0.95
Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J Biol Chem (2013) 0.94
Autophagosome dynamics in neurodegeneration at a glance. J Cell Sci (2015) 0.94
PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease. FEBS J (2014) 0.94
TRAP1 rescues PINK1 loss-of-function phenotypes. Hum Mol Genet (2013) 0.93
Selective escape of proteins from the mitochondria during mitophagy. Nat Commun (2013) 0.93
The interplay of neuronal mitochondrial dynamics and bioenergetics: implications for Parkinson's disease. Neurobiol Dis (2012) 0.93
Choline dehydrogenase interacts with SQSTM1/p62 to recruit LC3 and stimulate mitophagy. Autophagy (2014) 0.92
Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder. Nat Commun (2014) 0.91
Quality control gone wrong: mitochondria, lysosomal storage disorders and neurodegeneration. Br J Pharmacol (2014) 0.90
A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiology. J Mol Cell Cardiol (2014) 0.89
Function and characteristics of PINK1 in mitochondria. Oxid Med Cell Longev (2013) 0.89
Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis. PLoS One (2015) 0.88
SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria. Mol Biol Cell (2013) 0.87
Molecular events underlying Parkinson's disease - an interwoven tapestry. Front Neurol (2013) 0.86
Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress. Int J Mol Sci (2013) 0.86
PINK1-Parkin pathway activity is regulated by degradation of PINK1 in the mitochondrial matrix. PLoS Genet (2014) 0.85
PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes. PLoS One (2015) 0.85
Mitochondrial quality control: Easy come, easy go. Biochim Biophys Acta (2015) 0.85
PINK1 kinase catalytic activity is regulated by phosphorylation on serines 228 and 402. J Biol Chem (2014) 0.84
Tom70 is essential for PINK1 import into mitochondria. PLoS One (2013) 0.84
The ubiquitin signal and autophagy: an orchestrated dance leading to mitochondrial degradation. EMBO Rep (2016) 0.84
Unconventional PINK1 localization to the outer membrane of depolarized mitochondria drives Parkin recruitment. J Cell Sci (2015) 0.84
Control of mitochondrial integrity in ageing and disease. Philos Trans R Soc Lond B Biol Sci (2014) 0.83
Site-specific Interaction Mapping of Phosphorylated Ubiquitin to Uncover Parkin Activation. J Biol Chem (2015) 0.82
Mitochondrial impairment increases FL-PINK1 levels by calcium-dependent gene expression. Neurobiol Dis (2013) 0.82
Beyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial health. Antioxid Redox Signal (2015) 0.82
Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. Cell Death Differ (2015) 0.82
Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy (2016) 0.81
Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathy. Antioxid Redox Signal (2015) 0.81
Impaired sense of smell in a Drosophila Parkinson's model. PLoS One (2013) 0.81
Mitochondrial dysfunction in cardiac aging. Biochim Biophys Acta (2015) 0.80
BNIP3 Protein Suppresses PINK1 Kinase Proteolytic Cleavage to Promote Mitophagy. J Biol Chem (2016) 0.80
Loss of Mitochondrial Function Impairs Lysosomes. J Biol Chem (2016) 0.80
Parkin structure and function. FEBS J (2015) 0.80
Intramembrane protease PARL defines a negative regulator of PINK1- and PARK2/Parkin-dependent mitophagy. Autophagy (2015) 0.79
Endothelial uncoupling protein 2 regulates mitophagy and pulmonary hypertension during intermittent hypoxia. Arterioscler Thromb Vasc Biol (2015) 0.79
Emerging modes of PINK1 signaling: another task for MARK2. Front Mol Neurosci (2014) 0.79
Nitric oxide induction of Parkin translocation in PTEN-induced putative kinase 1 (PINK1) deficiency: functional role of neuronal nitric oxide synthase during mitophagy. J Biol Chem (2015) 0.78
Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy. J Biol Chem (2014) 0.78
Upregulation of human PINK1 gene expression by NFκB signalling. Mol Brain (2014) 0.78
Ubiquitin phosphorylation in Parkinson's disease: Implications for pathogenesis and treatment. Transl Neurodegener (2016) 0.77
Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker. Front Cell Neurosci (2016) 0.77
WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner. Oncogene (2017) 0.77
Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-κB Pathway and Promotes Non-selective Mitophagy. J Biol Chem (2015) 0.76
PINK1, Parkin, and Mitochondrial Quality Control: What can we Learn about Parkinson's Disease Pathobiology? J Parkinsons Dis (2016) 0.76
Macroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteins. Cells (2012) 0.76
Perturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin. Sci Rep (2015) 0.76
Angiotensinogen Import in Isolated Proximal Tubules: Evidence for Mitochondrial Trafficking and Uptake. Am J Physiol Renal Physiol (2016) 0.75
The Close Interconnection between Mitochondrial Dynamics and Mitophagy in Cancer. Front Oncol (2017) 0.75
Mitochondrial Quality Control Proteases in Neuronal Welfare. J Neuroimmune Pharmacol (2016) 0.75
PINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease. Front Mol Neurosci (2017) 0.75
Neuronal Mitophagy in Neurodegenerative Diseases. Front Mol Neurosci (2017) 0.75
The PINK1 p.I368N mutation affects protein stability and ubiquitin kinase activity. Mol Neurodegener (2017) 0.75
Drosophila clueless is involved in Parkin-dependent mitophagy by promoting VCP-mediated Marf degradation. Hum Mol Genet (2016) 0.75
Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation. Nat Commun (2017) 0.75
Clinical implications from proteomic studies in neurodegenerative diseases: lessons from mitochondrial proteins. Expert Rev Proteomics (2016) 0.75
Mutations in the substrate binding glycine-rich loop of the mitochondrial processing peptidase-α protein (PMPCA) cause a severe mitochondrial disease. Cold Spring Harb Mol Case Stud (2016) 0.75
Functional implications of mitochondrial reactive oxygen species generated by oncogenic viruses. Front Biol (Beijing) (2014) 0.75
BAG2 Gene-mediated Regulation of PINK1 Protein Is Critical for Mitochondrial Translocation of PARKIN and Neuronal Survival. J Biol Chem (2015) 0.75
HIV-1 Vpr disrupts mitochondria axonal transport and accelerates neuronal aging. Neuropharmacology (2017) 0.75
Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility. Proc Natl Acad Sci U S A (2016) 0.75
MicroRNA-181a suppresses parkin-mediated mitophagy and sensitizes neuroblastoma cells to mitochondrial uncoupler-induced apoptosis. Oncotarget (2016) 0.75
Counteracting PINK/Parkin Deficiency in the Activation of Mitophagy: A Potential Therapeutic Intervention for Parkinson's Disease. Curr Neuropharmacol (2016) 0.75
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol (2008) 17.81
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biol (2010) 11.85
Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A (1984) 7.39
Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci (2006) 4.87
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. J Cell Biol (2010) 3.68
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. Genes Cells (2010) 2.91
Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet (2010) 2.66
Mitochondrial processing peptidases. Biochim Biophys Acta (2002) 2.53
Parkinson's disease: genetics and pathogenesis. Annu Rev Pathol (2011) 2.39
PINK1 cleavage at position A103 by the mitochondrial protease PARL. Hum Mol Genet (2010) 2.30
Characterization of PINK1 processing, stability, and subcellular localization. J Neurochem (2008) 2.29
Protein degradation within mitochondria: versatile activities of AAA proteases and other peptidases. Crit Rev Biochem Mol Biol (2007) 2.18
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem (2011) 1.93
Mitochondrial shape changes: orchestrating cell pathophysiology. EMBO Rep (2010) 1.61
Mitophagy: the latest problem for Parkinson's disease. Trends Mol Med (2010) 1.41
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. Hum Mol Genet (2011) 1.35
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The MAS-encoded processing protease of yeast mitochondria. Overproduction and characterization of its two nonidentical subunits. J Biol Chem (1990) 1.11
Lateral release of proteins from the TOM complex into the outer membrane of mitochondria. EMBO J (2011) 0.95
Glycine-rich loop of mitochondrial processing peptidase alpha-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20. J Mol Biol (2010) 0.87
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The PINK1/Parkin pathway regulates mitochondrial morphology. Proc Natl Acad Sci U S A (2008) 7.41
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nat Cell Biol (2006) 4.05
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proc Natl Acad Sci U S A (2005) 3.83
Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol (2007) 3.61
Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities. J Biol Chem (2001) 3.54
Parkin and PINK1 function in a vesicular trafficking pathway regulating mitochondrial quality control. EMBO J (2014) 2.93
Structure of parkin reveals mechanisms for ubiquitin ligase activation. Science (2013) 2.84
Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers. Curr Biol (2008) 2.67
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci U S A (2008) 2.64
Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J (2005) 2.63
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death. J Cell Biol (2002) 2.47
A vesicular transport pathway shuttles cargo from mitochondria to lysosomes. Curr Biol (2012) 2.45
Genetic ablation of caveolin-1 confers protection against atherosclerosis. Arterioscler Thromb Vasc Biol (2003) 2.33
Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. J Neurosci (2002) 2.31
BAG5 inhibits parkin and enhances dopaminergic neuron degeneration. Neuron (2004) 2.29
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. J Biol Chem (2002) 2.21
The SUMO protease SENP5 is required to maintain mitochondrial morphology and function. J Cell Sci (2007) 2.12
Constitutive nuclear factor-kappa B activity is required for central neuron survival. J Neurosci (2002) 1.95
Caveolin, caveolae, and endothelial cell function. Arterioscler Thromb Vasc Biol (2003) 1.90
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2003) 1.87
Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts. Am J Physiol Cell Physiol (2002) 1.86
Vps35 mediates vesicle transport between the mitochondria and peroxisomes. Curr Biol (2010) 1.82
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Rep (2009) 1.80
Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. J Neurosci (2003) 1.74
Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. J Biol Chem (2007) 1.73
DJ-1/PARK7 is an important mediator of hypoxia-induced cellular responses. Proc Natl Acad Sci U S A (2009) 1.71
Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA. J Neurosci (2010) 1.69
Parkin-mediated monoubiquitination of the PDZ protein PICK1 regulates the activity of acid-sensing ion channels. Mol Biol Cell (2007) 1.69
Role of Cdk5-mediated phosphorylation of Prx2 in MPTP toxicity and Parkinson's disease. Neuron (2007) 1.65
Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. EMBO J (2002) 1.62
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am J Pathol (2002) 1.62
Calpain-regulated p35/cdk5 plays a central role in dopaminergic neuron death through modulation of the transcription factor myocyte enhancer factor 2. J Neurosci (2006) 1.61
Dissociating the dual roles of apoptosis-inducing factor in maintaining mitochondrial structure and apoptosis. EMBO J (2006) 1.59
SH3 domains from a subset of BAR proteins define a Ubl-binding domain and implicate parkin in synaptic ubiquitination. Mol Cell (2009) 1.59
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. J Neurosci (2005) 1.58
The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage. Proc Natl Acad Sci U S A (2007) 1.57
Involvement of interferon-gamma in microglial-mediated loss of dopaminergic neurons. J Neurosci (2007) 1.55
Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice. Mol Biol Cell (2003) 1.53
MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J (2010) 1.49
Mammalian polynucleotide phosphorylase is an intermembrane space RNase that maintains mitochondrial homeostasis. Mol Cell Biol (2006) 1.49
Positioning mitochondrial plasticity within cellular signaling cascades. Biochim Biophys Acta (2008) 1.48
Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease. Hum Mol Genet (2009) 1.47
Differential roles of nuclear and cytoplasmic cyclin-dependent kinase 5 in apoptotic and excitotoxic neuronal death. J Neurosci (2005) 1.44
ROS-dependent regulation of Parkin and DJ-1 localization during oxidative stress in neurons. Hum Mol Genet (2012) 1.42
The intracellular redox state is a core determinant of mitochondrial fusion. EMBO Rep (2012) 1.40
DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway. Proc Natl Acad Sci U S A (2010) 1.38
Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain. J Biol Chem (2001) 1.37
Mcl-1 is a key regulator of apoptosis during CNS development and after DNA damage. J Neurosci (2008) 1.37
Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis. J Biol Chem (2009) 1.37
Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. J Neural Transm (Vienna) (2011) 1.35
Pre-synaptic and post-synaptic localization of EphA4 and EphB2 in adult mouse forebrain. J Neurochem (2008) 1.34
Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins. Am J Pathol (2003) 1.33
Caveolin-1 and regulation of cellular cholesterol homeostasis. Am J Physiol Heart Circ Physiol (2006) 1.33
Structure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I. J Biol Chem (2006) 1.32
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology. Proc Natl Acad Sci U S A (2006) 1.30
The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. J Biol Chem (2004) 1.30
Apical role for BRG1 in cytokine-induced promoter assembly. Proc Natl Acad Sci U S A (2005) 1.30
Caveolin-1 expression enhances endothelial capillary tubule formation. J Biol Chem (2001) 1.30
EphA4 signaling regulates phospholipase Cgamma1 activation, cofilin membrane association, and dendritic spine morphology. J Neurosci (2007) 1.27
Reconstitution of mitochondria derived vesicle formation demonstrates selective enrichment of oxidized cargo. PLoS One (2012) 1.27
Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo. Proc Natl Acad Sci U S A (2005) 1.26
Unique requirement for Rb/E2F3 in neuronal migration: evidence for cell cycle-independent functions. Mol Cell Biol (2007) 1.24
The roles of kinases in familial Parkinson's disease. J Neurosci (2007) 1.22
The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability. Hum Mol Genet (2010) 1.21
p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death. J Neurosci (2004) 1.19
Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila. Hum Mol Genet (2010) 1.19
MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2. Mol Cell (2013) 1.18
Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis. FASEB J (2012) 1.17
Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat. J Cereb Blood Flow Metab (2002) 1.17
Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up? Front Neurol (2013) 1.17
p107 regulates neural precursor cells in the mammalian brain. J Cell Biol (2004) 1.15
Nuclear factor-(kappa)B modulates the p53 response in neurons exposed to DNA damage. J Neurosci (2004) 1.15
The retinoblastoma protein is essential for survival of postmitotic neurons. J Neurosci (2012) 1.15
Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction. J Cell Sci (2005) 1.14
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity. J Biol Chem (2010) 1.14
Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. J Neurosci (2004) 1.13
Staying cool in difficult times: mitochondrial dynamics, quality control and the stress response. Biochim Biophys Acta (2012) 1.13
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death. Nat Cell Biol (2010) 1.12
Mitochondria and the culture of the Borg: understanding the integration of mitochondrial function within the reticulum, the cell, and the organism. Bioessays (2010) 1.12
Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias. J Clin Invest (2014) 1.08
EphA4 is localized in clathrin-coated and synaptic vesicles in adult mouse brain. J Neurochem (2010) 1.07
The Chk1/Cdc25A pathway as activators of the cell cycle in neuronal death induced by camptothecin. J Neurosci (2006) 1.06
A novel cell-free mitochondrial fusion assay amenable for high-throughput screenings of fusion modulators. BMC Biol (2010) 1.04
Programmed cell death in Parkinson's disease. Cold Spring Harb Perspect Med (2012) 1.04
Mitochondrial dynamics in the regulation of neuronal cell death. Apoptosis (2007) 1.04
Mitochondrial vesicles: an ancient process providing new links to peroxisomes. Curr Opin Cell Biol (2009) 1.02
Emerging roles of mitochondria in the evolution, biogenesis, and function of peroxisomes. Front Physiol (2013) 1.02
Calpains mediate p53 activation and neuronal death evoked by DNA damage. J Biol Chem (2003) 1.02