Published in Neurobiol Dis on March 03, 2012
MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity. Neuro Oncol (2012) 1.12
Circulating cell-free microRNA as biomarkers for screening, diagnosis and monitoring of neurodegenerative diseases and other neurologic pathologies. Front Cell Neurosci (2013) 1.04
Transcriptome study of differential expression in schizophrenia. Hum Mol Genet (2013) 0.97
The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion. J Neurosci (2013) 0.97
MIR137 variants identified in psychiatric patients affect synaptogenesis and neuronal transmission gene sets. Mol Psychiatry (2014) 0.94
MicroRNAs: Key Regulators in the Central Nervous System and Their Implication in Neurological Diseases. Int J Mol Sci (2016) 0.87
Impulsivity and comorbid traits: a multi-step approach for finding putative responsible microRNAs in the amygdala. Front Neurosci (2014) 0.87
Therapeutic Action of Fluoxetine is Associated with a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Front Psychiatry (2013) 0.87
Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome. PLoS One (2014) 0.85
Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database. Mol Psychiatry (2015) 0.84
Mining the 3'UTR of autism-implicated genes for SNPs perturbing microRNA regulation. Genomics Proteomics Bioinformatics (2014) 0.83
miR-218 inhibits the proliferation of glioma U87 cells through the inactivation of the CDK6/cyclin D1/p21(Cip1/Waf1) pathway. Oncol Lett (2015) 0.81
miR-218 inhibits the migration and invasion of glioma U87 cells through the Slit2-Robo1 pathway. Oncol Lett (2015) 0.80
New innovations: therapeutic opportunities for intellectual disabilities. Ann Neurol (2013) 0.80
The epigenetic dimension of Alzheimer's disease: causal, consequence, or curiosity? Dialogues Clin Neurosci (2014) 0.80
Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders. Mol Brain (2015) 0.79
Dynamic Alterations of miR-34c Expression in the Hypothalamus of Male Rats after Early Adolescent Traumatic Stress. Neural Plast (2016) 0.79
PET Imaging of Epigenetic Influences on Alzheimer's Disease. Int J Alzheimers Dis (2015) 0.78
miR-17-92 Cluster Regulates Adult Hippocampal Neurogenesis, Anxiety, and Depression. Cell Rep (2016) 0.78
Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Transl Psychiatry (2016) 0.76
Plasma miR-34a-5p and miR-545-3p as Early Biomarkers of Alzheimer's Disease: Potential and Limitations. Mol Neurobiol (2016) 0.76
MicroRNA-130b promotes cell migration and invasion by inhibiting peroxisome proliferator-activated receptor-γ in human glioma. Oncol Lett (2017) 0.75
Association of new deletion/duplication region at chromosome 1p21 with intellectual disability, severe speech deficit and autism spectrum disorder-like behavior: an all-in approach to solving the DPYD enigma. Transl Neurosci (2015) 0.75
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
Prediction of mammalian microRNA targets. Cell (2003) 53.70
Combinatorial microRNA target predictions. Nat Genet (2005) 50.48
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95
Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55
The impact of microRNAs on protein output. Nature (2008) 32.39
Widespread changes in protein synthesis induced by microRNAs. Nature (2008) 31.44
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet (1999) 22.84
Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature (2008) 20.31
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol (2005) 18.94
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell (1991) 17.00
The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet (2010) 15.87
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature (2009) 14.07
Autism as a strongly genetic disorder: evidence from a British twin study. Psychol Med (1995) 12.70
MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16
microRNA target predictions in animals. Nat Genet (2006) 10.76
Schizophrenia as a complex trait: evidence from a meta-analysis of twin studies. Arch Gen Psychiatry (2003) 10.44
Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet (2008) 10.19
A brain-specific microRNA regulates dendritic spine development. Nature (2006) 10.18
Autism genome-wide copy number variation reveals ubiquitin and neuronal genes. Nature (2009) 9.47
Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35
A MicroRNA feedback circuit in midbrain dopamine neurons. Science (2007) 8.33
Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell (2007) 7.99
A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: report of 35 cases. Ann Neurol (1983) 6.80
A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. Proc Natl Acad Sci U S A (2005) 6.61
Altered synaptic plasticity in a mouse model of fragile X mental retardation. Proc Natl Acad Sci U S A (2002) 6.45
Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev (2002) 6.43
miRBase: the microRNA sequence database. Methods Mol Biol (2006) 6.17
A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev (2002) 6.10
Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78
Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11. Proc Natl Acad Sci U S A (1995) 5.62
Infantile autism: a genetic study of 21 twin pairs. J Child Psychol Psychiatry (1977) 5.55
Comparative genome hybridization suggests a role for NRXN1 and APBA2 in schizophrenia. Hum Mol Genet (2007) 5.28
miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci (2009) 5.27
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci (2004) 4.69
Exome sequencing supports a de novo mutational paradigm for schizophrenia. Nat Genet (2011) 4.67
Support for the involvement of large copy number variants in the pathogenesis of schizophrenia. Hum Mol Genet (2009) 4.52
Cerebellar neurodegeneration in the absence of microRNAs. J Exp Med (2007) 4.48
A new syndrome involving cleft palate, cardiac anomalies, typical facies, and learning disabilities: velo-cardio-facial syndrome. Cleft Palate J (1978) 4.23
Drosophila fragile X-related gene regulates the MAP1B homolog Futsch to control synaptic structure and function. Cell (2001) 4.21
A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. J Child Psychol Psychiatry (1989) 4.04
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron (2010) 3.96
MicroRNAs can generate thresholds in target gene expression. Nat Genet (2011) 3.90
Microdeletion/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders. J Med Genet (2008) 3.87
Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome. Ann Neurol (1985) 3.83
Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA. Nat Neurosci (2007) 3.81
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 3.76
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature (2009) 3.66
The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci (2008) 3.62
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet (2011) 3.59
Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell (2010) 3.57
A functional screen implicates microRNA-138-dependent regulation of the depalmitoylation enzyme APT1 in dendritic spine morphogenesis. Nat Cell Biol (2009) 3.44
Noncoding RNAs in the mammalian central nervous system. Annu Rev Neurosci (2006) 3.41
Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus. J Neurosci (2008) 3.33
Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. Neuron (2009) 3.27
microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder. Genome Biol (2007) 3.26
Prevalence of fragile X syndrome. Am J Med Genet (1996) 3.19
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. Cell Stem Cell (2010) 3.18
The fragile X syndrome protein represses activity-dependent translation through CYFIP1, a new 4E-BP. Cell (2008) 3.10
Experimental strategies for microRNA target identification. Nucleic Acids Res (2011) 3.00
A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination. Nat Struct Mol Biol (2009) 2.96
Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia. Nature (2010) 2.92
The pathophysiology of fragile x syndrome. Annu Rev Genomics Hum Genet (2007) 2.85
Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn (2006) 2.83
Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia. Arch Gen Psychiatry (2005) 2.78
Alternative miRNA biogenesis pathways and the interpretation of core miRNA pathway mutants. Mol Cell (2011) 2.73
Molecular mapping of twenty-four features of Down syndrome on chromosome 21. Eur J Hum Genet (1993) 2.73
Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations. Biol Psychiatry (2002) 2.69
Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J (2009) 2.65
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci (2010) 2.54
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome. Dev Cell (2008) 2.51
Heterogeneous dysregulation of microRNAs across the autism spectrum. Neurogenetics (2008) 2.50
Comparative sequence analysis reveals an intricate network among REST, CREB and miRNA in mediating neuronal gene expression. Genome Biol (2006) 2.49
MicroRNA miR-124 regulates neurite outgrowth during neuronal differentiation. Exp Cell Res (2008) 2.46
Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily. Genes Cells (2001) 2.43
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changes. Acta Neuropathol (2010) 2.42
Dysregulation of miRNA 181b in the temporal cortex in schizophrenia. Hum Mol Genet (2008) 2.33
microRNA-132 regulates dendritic growth and arborization of newborn neurons in the adult hippocampus. Proc Natl Acad Sci U S A (2010) 2.28
MicroRNAs potentiate neural development. Neuron (2009) 2.25
Schizophrenia is associated with an increase in cortical microRNA biogenesis. Mol Psychiatry (2009) 2.16
Selective dendritic alterations in the cortex of Rett syndrome. J Neuropathol Exp Neurol (1995) 2.15
The behavioral spectrum of Gilles de la Tourette syndrome. J Neuropsychiatry Clin Neurosci (2009) 2.14
Expression of microRNAs and their precursors in synaptic fractions of adult mouse forebrain. J Neurochem (2008) 2.07
MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci (2011) 2.03
Loss of individual microRNAs causes mutant phenotypes in sensitized genetic backgrounds in C. elegans. Curr Biol (2010) 2.02
MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A (2009) 2.00
Rett syndrome: confirmation of X-linked dominant inheritance, and localization of the gene to Xq28. Am J Hum Genet (1998) 1.98
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation. Neuron (2009) 1.96
Reduced communication between frontal and temporal lobes during talking in schizophrenia. Biol Psychiatry (2002) 1.94
Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nat Neurosci (2008) 1.92
Retracted Human chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts. Biochem Biophys Res Commun (2008) 1.91
Brain expressed microRNAs implicated in schizophrenia etiology. PLoS One (2007) 1.85
Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Hum Mol Genet (2006) 1.84
Excess protein synthesis in Drosophila fragile X mutants impairs long-term memory. Nat Neurosci (2008) 1.83
Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation. J Neurosci (2007) 1.78
Strong association of de novo copy number mutations with sporadic schizophrenia. Nat Genet (2008) 10.19
Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia. Nat Genet (2004) 4.71
Exome sequencing supports a de novo mutational paradigm for schizophrenia. Nat Genet (2011) 4.67
Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet (2008) 3.76
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet (2006) 3.54
Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia. Nature (2011) 3.51
Spontaneous neural activity is required for the establishment and maintenance of the olfactory sensory map. Neuron (2004) 3.50
De novo gene mutations highlight patterns of genetic and neural complexity in schizophrenia. Nat Genet (2012) 3.49
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia. Nature (2010) 2.92
Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Nat Genet (2004) 2.77
Modeling madness in mice: one piece at a time. Neuron (2006) 2.60
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia. Nat Rev Neurosci (2010) 2.54
A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition. Proc Natl Acad Sci U S A (2008) 2.37
Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice. Proc Natl Acad Sci U S A (2006) 2.32
Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12. Science (2003) 2.20
Palmitoylation-dependent neurodevelopmental deficits in a mouse model of 22q11 microdeletion. Nat Neurosci (2008) 1.92
Genetic variation at the 22q11 PRODH2/DGCR6 locus presents an unusual pattern and increases susceptibility to schizophrenia. Proc Natl Acad Sci U S A (2002) 1.92
Transcriptional and behavioral interaction between 22q11.2 orthologs modulates schizophrenia-related phenotypes in mice. Nat Neurosci (2005) 1.91
Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO. Curr Biol (2004) 1.87
Site-specific role of catechol-O-methyltransferase in dopamine overflow within prefrontal cortex and dorsal striatum. J Neurosci (2007) 1.75
The molecular genetics of the 22q11-associated schizophrenia. Brain Res Mol Brain Res (2004) 1.74
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. Proc Natl Acad Sci U S A (2009) 1.73
Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex. Proc Natl Acad Sci U S A (2011) 1.65
Genetic variation in the 22q11 locus and susceptibility to schizophrenia. Proc Natl Acad Sci U S A (2002) 1.60
Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit. Proc Natl Acad Sci U S A (2003) 1.54
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice. Eur J Neurosci (2002) 1.51
Akt1 deficiency affects neuronal morphology and predisposes to abnormalities in prefrontal cortex functioning. Proc Natl Acad Sci U S A (2006) 1.44
Genetic modulation of BDNF signaling affects the outcome of axonal competition in vivo. Curr Biol (2007) 1.40
S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. Neuron (2011) 1.35
Diverse types of genetic variation converge on functional gene networks involved in schizophrenia. Nat Neurosci (2012) 1.34
Genomewide scan in families with schizophrenia from the founder population of Afrikaners reveals evidence for linkage and uniparental disomy on chromosome 1. Am J Hum Genet (2004) 1.34
Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder. Am J Hum Genet (2003) 1.32
Neuropsychological characteristics of children with the 22q11 Deletion Syndrome: a descriptive analysis. Child Neuropsychol (2005) 1.25
Lower prepulse inhibition in children with the 22q11 deletion syndrome. Am J Psychiatry (2005) 1.25
MicroRNAs in psychiatric and neurodevelopmental disorders. Brain Res (2010) 1.22
Effect of dopamine uptake inhibition on brain catecholamine levels and locomotion in catechol-O-methyltransferase-disrupted mice. J Pharmacol Exp Ther (2002) 1.19
Derepression of a neuronal inhibitor due to miRNA dysregulation in a schizophrenia-related microdeletion. Cell (2013) 1.19
The best of times, the worst of times for psychiatric disease. Nat Neurosci (2012) 1.18
Quantitative role of COMT in dopamine clearance in the prefrontal cortex of freely moving mice. J Neurochem (2010) 1.17
The 22q11.2 microdeletion: fifteen years of insights into the genetic and neural complexity of psychiatric disorders. Int J Dev Neurosci (2010) 1.16
The genetic architecture of schizophrenia: new mutations and emerging paradigms. Annu Rev Med (2011) 1.14
Networks of attention in children with the 22q11 deletion syndrome. Dev Neuropsychol (2004) 1.13
Scan statistic-based analysis of exome sequencing data identifies FAN1 at 15q13.3 as a susceptibility gene for schizophrenia and autism. Proc Natl Acad Sci U S A (2013) 1.13
Cognition in mouse models of schizophrenia susceptibility genes. Schizophr Bull (2009) 1.11
Genetic and cognitive windows into circuit mechanisms of psychiatric disease. Trends Neurosci (2011) 1.10
Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice. Proc Natl Acad Sci U S A (2011) 1.09
Resistance to salt-induced hypertension in catechol-O-methyltransferase-gene-disrupted mice. J Hypertens (2003) 1.01
Phenotypic characterization and genealogical tracing in an Afrikaner schizophrenia database. Am J Med Genet B Neuropsychiatr Genet (2004) 1.00
The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion. J Neurosci (2013) 0.97
A signaling pathway AKTing up in schizophrenia. J Clin Invest (2008) 0.96
Nogo Receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches. PLoS One (2007) 0.96
Decreased phosphorylation of NMDA receptor type 1 at serine 897 in brains of patients with Schizophrenia. J Neurosci (2004) 0.95
Chronic adolescent exposure to Δ-9-tetrahydrocannabinol in COMT mutant mice: impact on psychosis-related and other phenotypes. Neuropsychopharmacology (2010) 0.93
Development of animal models for schizophrenia. Dis Model Mech (2010) 0.93
D-amphetamine responses in catechol-O-methyltransferase (COMT) disrupted mice. Psychopharmacology (Berl) (2003) 0.92
Extended intermarker linkage disequilibrium in the Afrikaners. Genome Res (2002) 0.91