Published in J Biol Chem on March 13, 2012
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell (2012) 2.54
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix. J Biol Chem (2013) 1.78
Retracted Sirtuin-3 modulates Bak- and Bax-dependent apoptosis. J Cell Sci (2012) 1.64
SIRT3 deficiency exacerbates ischemia-reperfusion injury: implication for aged hearts. Am J Physiol Heart Circ Physiol (2014) 1.60
Extended wakefulness: compromised metabolics in and degeneration of locus ceruleus neurons. J Neurosci (2014) 1.59
The emerging and diverse roles of sirtuins in cancer: a clinical perspective. Onco Targets Ther (2013) 1.57
Nonenzymatic protein acylation as a carbon stress regulated by sirtuin deacylases. Mol Cell (2014) 1.56
Cyclophilin D modulates mitochondrial acetylome. Circ Res (2013) 1.53
Sirtuin catalysis and regulation. J Biol Chem (2012) 1.35
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
Mitochondrial protein acetylation as a cell-intrinsic, evolutionary driver of fat storage: chemical and metabolic logic of acetyl-lysine modifications. Crit Rev Biochem Mol Biol (2013) 1.17
Protective effects of sirtuins in cardiovascular diseases: from bench to bedside. Eur Heart J (2015) 1.11
Interaction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress. Cell Death Dis (2013) 1.09
Mitochondrial sirtuins and their relationships with metabolic disease and cancer. Antioxid Redox Signal (2015) 1.09
The sirtuins, oxidative stress and aging: an emerging link. Aging (Albany NY) (2013) 1.08
Calcium and ROS: A mutual interplay. Redox Biol (2015) 1.05
Pharmacological activation of NQO1 increases NAD⁺ levels and attenuates cisplatin-mediated acute kidney injury in mice. Kidney Int (2013) 1.01
Sirtuin regulation in aging and injury. Biochim Biophys Acta (2015) 0.98
Forever young: SIRT3 a shield against mitochondrial meltdown, aging, and neurodegeneration. Front Aging Neurosci (2013) 0.97
Metabolic control of epigenetics in cancer. Nat Rev Cancer (2016) 0.94
Metabolic inflexibility and protein lysine acetylation in heart mitochondria of a chronic model of type 1 diabetes. Biochem J (2013) 0.94
Mitochondrial biogenesis through activation of nuclear signaling proteins. Cold Spring Harb Perspect Biol (2013) 0.94
Mechanisms and Dynamics of Protein Acetylation in Mitochondria. Trends Biochem Sci (2016) 0.91
Mitochondrial SIRT3 Mediates Adaptive Responses of Neurons to Exercise and Metabolic and Excitatory Challenges. Cell Metab (2015) 0.90
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism. Cell Metab (2016) 0.89
Metabolism leaves its mark on the powerhouse: recent progress in post-translational modifications of lysine in mitochondria. Front Physiol (2014) 0.89
A Class of Reactive Acyl-CoA Species Reveals the Non-enzymatic Origins of Protein Acylation. Cell Metab (2017) 0.89
SIRT3-dependent GOT2 acetylation status affects the malate-aspartate NADH shuttle activity and pancreatic tumor growth. EMBO J (2015) 0.87
Do sirtuins promote mammalian longevity? A critical review on its relevance to the longevity effect induced by calorie restriction. Mol Cells (2013) 0.85
Maintaining good hearing: calorie restriction, Sirt3, and glutathione. Exp Gerontol (2013) 0.85
Pivotal Importance of STAT3 in Protecting the Heart from Acute and Chronic Stress: New Advancement and Unresolved Issues. Front Cardiovasc Med (2015) 0.85
AMPK/α-Ketoglutarate Axis Dynamically Mediates DNA Demethylation in the Prdm16 Promoter and Brown Adipogenesis. Cell Metab (2016) 0.84
Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development. Basic Res Cardiol (2013) 0.84
Chronic unpredictable stress (CUS)-induced anxiety and related mood disorders in a zebrafish model: altered brain proteome profile implicates mitochondrial dysfunction. PLoS One (2013) 0.84
Genome-wide gene expression profiles in antioxidant pathways and their potential sex differences and connections to vitamin C in mice. Int J Mol Sci (2013) 0.84
Effects of Oxidative Stress on Mesenchymal Stem Cell Biology. Oxid Med Cell Longev (2016) 0.84
Loss of SIRT3 Provides Growth Advantage for B Cell Malignancies. J Biol Chem (2015) 0.84
SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis. Oncotarget (2016) 0.83
Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice. Am J Physiol Heart Circ Physiol (2016) 0.83
Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study "Treviso Longeva (TRELONG)". Age (Dordr) (2013) 0.83
Regulation of S-adenosylhomocysteine hydrolase by lysine acetylation. J Biol Chem (2014) 0.82
Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation. J Mol Cell Cardiol (2015) 0.82
SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3β. Mol Cell Biol (2015) 0.81
Potential Modulation of Sirtuins by Oxidative Stress. Oxid Med Cell Longev (2015) 0.81
Protective Role of Sirtuin3 (SIRT3) in Oxidative Stress Mediated by Hepatitis B Virus X Protein Expression. PLoS One (2016) 0.81
Making sense of oxidative stress in obstructive sleep apnea: mediator or distracter? Front Neurol (2012) 0.81
Proteome-wide lysine acetylation in cortical astrocytes and alterations that occur during infection with brain parasite Toxoplasma gondii. PLoS One (2015) 0.81
CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance. Mol Cancer Ther (2015) 0.79
The protein deacetylase SIRT3 prevents oxidative stress-induced keratinocyte differentiation. J Biol Chem (2013) 0.79
Sirtuin deacetylases as therapeutic targets in the nervous system. Neurotherapeutics (2013) 0.79
SIRT3 Enhances Glycolysis and Proliferation in SIRT3-Expressing Gastric Cancer Cells. PLoS One (2015) 0.78
Sirtuins in glucose and lipid metabolism. Oncotarget (2017) 0.78
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Proc Natl Acad Sci U S A (2016) 0.77
Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice. Oncotarget (2017) 0.77
Aging Promotes Sirtuin 3-Dependent Cartilage Superoxide Dismutase 2 Acetylation and Osteoarthritis. Arthritis Rheumatol (2016) 0.77
PGC-1α/ERRα-Sirt3 Pathway Regulates DAergic Neuronal Death by Directly Deacetylating SOD2 and ATP Synthase β. Antioxid Redox Signal (2015) 0.77
Role of mitochondrial dysfunction in cancer progression. Exp Biol Med (Maywood) (2016) 0.77
Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1). J Biol Chem (2016) 0.77
The role of caloric load and mitochondrial homeostasis in the regulation of the NLRP3 inflammasome. Cell Mol Life Sci (2016) 0.76
SIRT3 blocks myofibroblast differentiation and pulmonary fibrosis by preventing mitochondrial DNA damage. Am J Physiol Lung Cell Mol Physiol (2016) 0.76
Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study. PLoS One (2016) 0.76
Mitochondrial sirtuins in the heart. Heart Fail Rev (2016) 0.76
Acetyl-L-carnitine increases mitochondrial protein acetylation in the aged rat heart. Mech Ageing Dev (2015) 0.76
SIRT3-mediated dimerization of IDH2 directs cancer cell metabolism and tumor growth. Cancer Res (2017) 0.76
Overexpression of SIRT3 disrupts mitochondrial proteostasis and cell cycle progression. Protein Cell (2016) 0.75
PGC-1α and fasting-induced PDH regulation in mouse skeletal muscle. Physiol Rep (2017) 0.75
Escaping Death: Mitochondrial Redox Homeostasis in Cancer Cells. Front Oncol (2017) 0.75
An Artificial Reaction Promoter Modulates Mitochondrial Functions via Chemically Promoting Protein Acetylation. Sci Rep (2016) 0.75
Poly(ADP-ribose) polymerase 1 contributes to oxidative stress through downregulation of sirtuin 3 during cisplatin nephrotoxicity. Anat Cell Biol (2016) 0.75
Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2. Basic Res Cardiol (2016) 0.75
High Sensitivity of SIRT3 Deficient Hearts to Ischemia-Reperfusion Is Associated with Mitochondrial Abnormalities. Front Pharmacol (2017) 0.75
Circadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome. Cell Rep (2017) 0.75
Cytoprotective Effect of the UCP2-SIRT3 Signaling Pathway by Decreasing Mitochondrial Oxidative Stress on Cerebral Ischemia-Reperfusion Injury. Int J Mol Sci (2017) 0.75
Studies on the regulatory mechanism of isocitrate dehydrogenase 2 using acetylation mimics. Sci Rep (2017) 0.75
Metabolic Dysfunction in Parkinson's Disease: Bioenergetics, Redox Homeostasis and Central Carbon Metabolism. Brain Res Bull (2017) 0.75
Sirt1-Sirt3 axis regulates human blood-brain barrier permeability in response to ischemia. Redox Biol (2017) 0.75
Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science (2009) 20.49
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature (2009) 19.65
Free radicals in the physiological control of cell function. Physiol Rev (2002) 19.62
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer Cell (2010) 13.13
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell (2006) 11.38
Oxidative stress, caloric restriction, and aging. Science (1996) 11.07
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
Caloric restriction delays disease onset and mortality in rhesus monkeys. Science (2009) 9.84
Gene expression profile of aging and its retardation by caloric restriction. Science (1999) 8.06
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol (2007) 7.97
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. Nature (2011) 7.94
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A (2006) 7.00
Reductive carboxylation supports growth in tumour cells with defective mitochondria. Nature (2011) 6.57
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci U S A (2008) 6.53
SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature (2010) 6.48
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci U S A (2006) 5.96
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med (2010) 5.68
SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. Cancer Cell (2010) 5.40
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability. Proc Natl Acad Sci U S A (2011) 5.24
ROS stress in cancer cells and therapeutic implications. Drug Resist Updat (2004) 5.20
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metab (2010) 4.97
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem (2005) 4.80
Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress. Mol Cell (2010) 4.19
SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. Cancer Cell (2011) 3.71
Genetically encoding N(epsilon)-acetyllysine in recombinant proteins. Nat Chem Biol (2008) 3.68
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol (2008) 3.27
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One (2008) 3.25
A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation. Mol Cell (2009) 3.11
Calorie restriction alters mitochondrial protein acetylation. Aging Cell (2009) 2.73
ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep (2002) 2.61
Regulation of intermediary metabolism by protein acetylation. Trends Biochem Sci (2010) 2.36
SirT3 suppresses hypoxia inducible factor 1α and tumor growth by inhibiting mitochondrial ROS production. Oncogene (2011) 2.35
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell (2011) 2.29
The role of mitochondria in reactive oxygen species metabolism and signaling. Ann N Y Acad Sci (2008) 2.27
Tumour suppressor SIRT3 deacetylates and activates manganese superoxide dismutase to scavenge ROS. EMBO Rep (2011) 2.20
Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase. J Biol Chem (2001) 1.90
Mitochondria damage checkpoint, aging, and cancer. Ann N Y Acad Sci (2006) 1.76
NAD+-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10. J Biol Chem (2009) 1.43
Inactivation of NADP+-dependent isocitrate dehydrogenase by peroxynitrite. Implications for cytotoxicity and alcohol-induced liver injury. J Biol Chem (2003) 1.32
SIRT3 and cancer: tumor promoter or suppressor? Biochim Biophys Acta (2011) 1.28
The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies. J Biol Chem (1974) 1.28
Spectrophotometric determination of oxidized and reduced pyridine nucleotides in erythrocytes using a single extraction procedure. Anal Biochem (1987) 1.21
The regeneration of reduced glutathione in rat forebrain mitochondria identifies metabolic pathways providing the NADPH required. Neurosci Lett (1999) 1.16
Autoacetylation of the histone acetyltransferase Rtt109. J Biol Chem (2011) 1.08
Friedreich's ataxia reveals a mechanism for coordinate regulation of oxidative metabolism via feedback inhibition of the SIRT3 deacetylase. Hum Mol Genet (2012) 1.07
Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells. Biochim Biophys Acta (2011) 0.96
Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. Protein Sci (2008) 0.91
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell (2003) 8.34
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci U S A (2006) 7.00
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
Mechanism of human SIRT1 activation by resveratrol. J Biol Chem (2005) 4.86
Histone H3-K56 acetylation is catalyzed by histone chaperone-dependent complexes. Mol Cell (2007) 3.38
SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metab (2010) 2.77
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell (2012) 2.54
Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice. Science (2013) 2.49
Essential role for the SANT domain in the functioning of multiple chromatin remodeling enzymes. Mol Cell (2002) 2.33
Sirt3 promotes the urea cycle and fatty acid oxidation during dietary restriction. Mol Cell (2011) 2.29
Substrate specificity and kinetic mechanism of the Sir2 family of NAD+-dependent histone/protein deacetylases. Biochemistry (2004) 2.11
Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins. J Biol Chem (2013) 2.03
The Sirtuin family: therapeutic targets to treat diseases of aging. Curr Opin Chem Biol (2008) 2.00
Mechanisms and molecular probes of sirtuins. Chem Biol (2008) 1.90
Structural identification of 2'- and 3'-O-acetyl-ADP-ribose as novel metabolites derived from the Sir2 family of beta -NAD+-dependent histone/protein deacetylases. J Biol Chem (2002) 1.88
Mechanism of nicotinamide inhibition and transglycosidation by Sir2 histone/protein deacetylases. J Biol Chem (2003) 1.87
Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75. Nat Struct Mol Biol (2008) 1.78
Chemical mechanisms of histone lysine and arginine modifications. Biochim Biophys Acta (2008) 1.69
Structure and biochemical functions of SIRT6. J Biol Chem (2011) 1.67
Assays for mechanistic investigations of protein/histone acetyltransferases. Methods (2005) 1.65
Catalysis and substrate selection by histone/protein lysine acetyltransferases. Curr Opin Struct Biol (2008) 1.64
Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. J Biol Chem (2002) 1.62
Binding of the CHD4 PHD2 finger to histone H3 is modulated by covalent modifications. Biochem J (2009) 1.59
Catalytic mechanism of a MYST family histone acetyltransferase. Biochemistry (2007) 1.57
Plant homeodomain (PHD) fingers of CHD4 are histone H3-binding modules with preference for unmodified H3K4 and methylated H3K9. J Biol Chem (2011) 1.55
Metabolite of SIR2 reaction modulates TRPM2 ion channel. J Biol Chem (2006) 1.55
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes. Anal Biochem (2009) 1.54
Small molecule regulation of Sir2 protein deacetylases. FEBS J (2005) 1.54
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine. Biochemistry (2006) 1.49
Mechanism-based inhibition of Sir2 deacetylases by thioacetyl-lysine peptide. Biochemistry (2007) 1.44
Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation. J Biol Chem (2004) 1.43
Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. J Biol Chem (2011) 1.42
Acetyl-lysine analog peptides as mechanistic probes of protein deacetylases. J Biol Chem (2007) 1.41
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Mol Cell (2012) 1.39
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proc Natl Acad Sci U S A (2012) 1.37
Sirtuin catalysis and regulation. J Biol Chem (2012) 1.35
KAT(ching) metabolism by the tail: insight into the links between lysine acetyltransferases and metabolism. Chembiochem (2010) 1.32
Where in the cell is SIRT3?--functional localization of an NAD+-dependent protein deacetylase. Biochem J (2008) 1.31
Probing the function of conserved residues in the serine/threonine phosphatase PP2Calpha. Biochemistry (2003) 1.28
Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose. Biochim Biophys Acta (2010) 1.25
Quantitative assays for characterization of the Sir2 family of NAD(+)-dependent deacetylases. Methods Enzymol (2004) 1.23
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation. J Biol Chem (2013) 1.20
SIRT3 substrate specificity determined by peptide arrays and machine learning. ACS Chem Biol (2010) 1.17
Structural basis for the recognition of a bisphosphorylated MAP kinase peptide by human VHR protein Phosphatase. Biochemistry (2002) 1.14
Sir2 deacetylases exhibit nucleophilic participation of acetyl-lysine in NAD+ cleavage. J Am Chem Soc (2007) 1.14
Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease. J Clin Invest (2013) 1.14
Nucleosome recognition by the Piccolo NuA4 histone acetyltransferase complex. Biochemistry (2007) 1.14
Hydrolase regulates NAD+ metabolites and modulates cellular redox. J Biol Chem (2009) 1.13
Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties. J Biol Chem (2011) 1.12
SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity. Biochemistry (2006) 1.11
Identification and characterization of small molecule inhibitors of a plant homeodomain finger. Biochemistry (2012) 1.11
Regulation of glycolytic enzyme phosphoglycerate mutase-1 by Sirt1 protein-mediated deacetylation. J Biol Chem (2011) 1.09
Autoacetylation of the histone acetyltransferase Rtt109. J Biol Chem (2011) 1.08
The acetyltransferase activity of CBP is required for wingless activation and H4 acetylation in Drosophila melanogaster. Mol Cell Biol (2002) 1.08
Modulating acetyl-CoA binding in the GCN5 family of histone acetyltransferases. J Biol Chem (2002) 1.08
Kinetic mechanism of the Rtt109-Vps75 histone acetyltransferase-chaperone complex. Biochemistry (2010) 1.06
Acetylation-dependent ADP-ribosylation by Trypanosoma brucei Sir2. J Biol Chem (2007) 1.06
Dynamic interplay between histone H3 modifications and protein interpreters: emerging evidence for a "histone language". Chembiochem (2010) 1.06
Catalytic activation of histone acetyltransferase Rtt109 by a histone chaperone. Proc Natl Acad Sci U S A (2010) 1.03
Analysis of O-acetyl-ADP-ribose as a target for Nudix ADP-ribose hydrolases. J Biol Chem (2002) 1.00
A combinatorial H4 tail library for exploring the histone code. Biochemistry (2008) 0.99
Site-specific reactivity of nonenzymatic lysine acetylation. ACS Chem Biol (2015) 0.99
Nuclear-cytoplasmic localization of acetyl coenzyme a synthetase-1 in the rat brain. J Comp Neurol (2010) 0.98
Multivalent recognition of histone tails by the PHD fingers of CHD5. Biochemistry (2012) 0.97
Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease. J Inherit Metab Dis (2010) 0.92
Synthesis and biochemical evaluation of O-acetyl-ADP-ribose and N-acetyl analogs. Org Biomol Chem (2007) 0.92
Dual-specificity protein tyrosine phosphatase VHR down-regulates c-Jun N-terminal kinase (JNK). Oncogene (2002) 0.91
Quantification of endogenous sirtuin metabolite O-acetyl-ADP-ribose. Anal Biochem (2008) 0.91
Quantification of SAHA-Dependent Changes in Histone Modifications Using Data-Independent Acquisition Mass Spectrometry. J Proteome Res (2015) 0.91
Linking SIRT2 to Parkinson's disease. ACS Chem Biol (2007) 0.90
Circadian control of fatty acid elongation by SIRT1 protein-mediated deacetylation of acetyl-coenzyme A synthetase 1. J Biol Chem (2014) 0.89
NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function. Cancer Discov (2014) 0.89
Catalysis and mechanistic insights into sirtuin activation. Chembiochem (2010) 0.89
Hydrolysis of O-acetyl-ADP-ribose isomers by ADP-ribosylhydrolase 3. J Biol Chem (2011) 0.88
Metabolic regulation of histone post-translational modifications. ACS Chem Biol (2015) 0.87
Intramolecular dephosphorylation of ERK by MKP3. Biochemistry (2003) 0.86
Processing mechanism and substrate selectivity of the core NuA4 histone acetyltransferase complex. Biochemistry (2011) 0.86
Ure(k)a! Sirtuins Regulate Mitochondria. Cell (2009) 0.83
Sirtuins caught in the act. Structure (2006) 0.81
Probing the transition-state structure of dual-specificity protein phosphatases using a physiological substrate mimic. Biochemistry (2004) 0.81
Disrupting the reader of histone language. Angew Chem Int Ed Engl (2011) 0.80
Structure of Arabidopsis thaliana At1g77540 protein, a minimal acetyltransferase from the COG2388 family. Biochemistry (2006) 0.79
Kinetic mechanism of adenine phosphoribosyltransferase from Leishmania donovani. Biochemistry (2002) 0.78
Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. Biochemistry (2011) 0.78
Methyl magic and HAT tricks. Nat Struct Biol (2002) 0.77
The C-terminus of human nucleotide receptor P2X7 is critical for receptor oligomerization and N-linked glycosylation. PLoS One (2013) 0.75
High-throughput strategy to identify inhibitors of histone-binding domains. Methods Enzymol (2012) 0.75