Published in Genome Res on April 12, 2012
Histone acetylation regulates intracellular pH. Mol Cell (2012) 1.30
Genomic occupancy of the transcriptional co-activators p300 and CBP. Transcription (2012) 0.97
Polycomb repressive complex 1 (PRC1) disassembles RNA polymerase II preinitiation complexes. J Biol Chem (2012) 0.95
Adenovirus small E1A employs the lysine acetylases p300/CBP and tumor suppressor Rb to repress select host genes and promote productive virus infection. Cell Host Microbe (2014) 0.95
In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse. Elife (2015) 0.94
Mediator and SAGA have distinct roles in Pol II preinitiation complex assembly and function. Cell Rep (2012) 0.91
Unabated adenovirus replication following activation of the cGAS/STING-dependent antiviral response in human cells. J Virol (2014) 0.86
Cellular GCN5 is a novel regulator of human adenovirus E1A-conserved region 3 transactivation. J Virol (2012) 0.86
Scl binds to primed enhancers in mesoderm to regulate hematopoietic and cardiac fate divergence. EMBO J (2015) 0.86
The Ino80 complex prevents invasion of euchromatin into silent chromatin. Genes Dev (2015) 0.85
A unique epigenetic signature is associated with active DNA replication loci in human embryonic stem cells. Epigenetics (2013) 0.85
EP400 Deposits H3.3 into Promoters and Enhancers during Gene Activation. Mol Cell (2015) 0.83
Small molecule inhibition of cAMP response element binding protein in human acute myeloid leukemia cells. Leukemia (2016) 0.82
Transcriptome sequencing and development of an expression microarray platform for liver infection in adenovirus type 5-infected Syrian golden hamsters. Virology (2015) 0.80
Adenovirus E1A targets the DREF nuclear factor to regulate virus gene expression, DNA replication, and growth. J Virol (2014) 0.79
Effects of Adenovirus Type 5 E1A Isoforms on Viral Replication in Arrested Human Cells. PLoS One (2015) 0.78
Viral epigenetics. Methods Mol Biol (2015) 0.78
Stabilization of SIRT7 deacetylase by viral oncoprotein HBx leads to inhibition of growth restrictive RPS7 gene and facilitates cellular transformation. Sci Rep (2015) 0.76
Borna disease virus phosphoprotein modulates epigenetic signaling in neurons to control viral replication. J Virol (2015) 0.76
Epigenetic changes mediated by polycomb repressive complex 2 and E2a are associated with drug resistance in a mouse model of lymphoma. Genome Med (2016) 0.75
Cbx3 maintains lineage specificity during neural differentiation. Genes Dev (2017) 0.75
Limited but durable changes to cellular gene expression in a model of latent adenovirus infection are reflected in childhood leukemic cell lines. Virology (2016) 0.75
Abf1 and other general regulatory factors control ribosome biogenesis gene expression in budding yeast. Nucleic Acids Res (2017) 0.75
Histone deacetylase inhibitors provoke a tumor supportive phenotype in pancreatic cancer associated fibroblasts. Oncotarget (2016) 0.75
Adenovirus core protein VII down-regulates the DNA damage response on the host genome. J Virol (2017) 0.75
Mot1, Ino80C, and NC2 Function Coordinately to Regulate Pervasive Transcription in Yeast and Mammals. Mol Cell (2017) 0.75
TopHat: discovering splice junctions with RNA-Seq. Bioinformatics (2009) 81.13
Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92
Histone modifications at human enhancers reflect global cell-type-specific gene expression. Nature (2009) 24.41
Function and activation of NF-kappa B in the immune system. Annu Rev Immunol (1994) 17.04
A unique chromatin signature uncovers early developmental enhancers in humans. Nature (2010) 14.02
Distinct epigenomic landscapes of pluripotent and lineage-committed human cells. Cell Stem Cell (2010) 8.74
The RB and p53 pathways in cancer. Cancer Cell (2002) 8.02
Resolving the functions of overlapping viral genes by site-specific mutagenesis at a mRNA splice site. Nature (1982) 5.61
Functional and mechanistic diversity of distal transcription enhancers. Cell (2011) 5.22
Highly specific antibodies determine histone acetylation site usage in yeast heterochromatin and euchromatin. Mol Cell (2001) 4.06
Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence. Cancer Cell (2010) 3.81
Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation. EMBO J (2010) 3.25
Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus. Oncogene (2005) 3.04
IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev (1992) 2.80
Adenovirus small e1a alters global patterns of histone modification. Science (2008) 2.43
Epigenetic reprogramming by adenovirus e1a. Science (2008) 2.38
E2F - at the crossroads of life and death. Trends Cell Biol (2008) 2.37
Myeloid deletion of SIRT1 induces inflammatory signaling in response to environmental stress. Mol Cell Biol (2010) 1.94
Nucleosome-like structural subunits of intranuclear parental adenovirus type 2 DNA. J Virol (1979) 1.54
A viral mechanism for remodeling chromatin structure in G0 cells. Mol Cell (2003) 1.53
Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor. Genes Dev (2007) 1.49
SAMMate: a GUI tool for processing short read alignments in SAM/BAM format. Source Code Biol Med (2011) 1.47
Role of the Rb/E2F pathway in cell growth control. J Cell Physiol (1997) 1.44
How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. Virology (2009) 1.33
Genome-wide assessment of differential roles for p300 and CBP in transcription regulation. Nucleic Acids Res (2010) 1.25
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes. Hepatology (2010) 1.25
Microarray and comparative genomics-based identification of genes and gene regulatory regions of the mouse immune system. BMC Genomics (2004) 1.25
The checkpoints of viral gene expression in productive and latent infection: the role of the HDAC/CoREST/LSD1/REST repressor complex. J Virol (2011) 1.20
Roles of SIRT1 in the acute and restorative phases following induction of inflammation. J Biol Chem (2010) 1.18
Genome-wide analysis of transcription factor E2F1 mutant proteins reveals that N- and C-terminal protein interaction domains do not participate in targeting E2F1 to the human genome. J Biol Chem (2011) 1.18
Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation. J Cell Sci (2010) 1.18
The SIRT2 deacetylase regulates autoacetylation of p300. Mol Cell (2008) 1.11
The transcription repressor, ZEB1, cooperates with CtBP2 and HDAC1 to suppress IL-2 gene activation in T cells. Int Immunol (2009) 1.10
Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection. J Virol (2011) 1.09
Cellular and viral chromatin proteins are positive factors in the regulation of adenovirus gene expression. Nucleic Acids Res (2010) 1.08
pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F. Proc Natl Acad Sci U S A (2000) 1.02
E1A interacts with two opposing transcriptional pathways to induce quiescent cells into S phase. J Virol (2010) 0.98
Adenovirus induction of an interferon-regulatory factor during entry into the late phase of infection. J Virol (1998) 0.96
CCL2-independent role of CCR2 in immune responses against Leishmania major. Parasite Immunol (2007) 0.95
Assembly of helper-dependent adenovirus DNA into chromatin promotes efficient gene expression. J Virol (2011) 0.94
Inhibition of Sirt1 promotes neural progenitors toward motoneuron differentiation from human embryonic stem cells. Biochem Biophys Res Commun (2010) 0.92
Two-dimensional gel analysis of histones and other H2AX-related methods. Methods Enzymol (2004) 0.81
Highly efficient refractive Gaussian-to-tophat beam shaper for compact terahertz imager. Appl Opt (2010) 0.77
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature (2008) 26.78
Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis. Cell (2006) 15.24
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell (2005) 10.68
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature (2010) 8.84
The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools. Nucleic Acids Res (2011) 8.18
Conservation and divergence of methylation patterning in plants and animals. Proc Natl Acad Sci U S A (2010) 7.30
Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell (2005) 7.21
Global histone modification patterns predict risk of prostate cancer recurrence. Nature (2005) 7.03
Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol (2011) 5.41
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell (2008) 5.40
Relationship between nucleosome positioning and DNA methylation. Nature (2010) 5.27
BS Seeker: precise mapping for bisulfite sequencing. BMC Bioinformatics (2010) 4.66
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. Science (2003) 4.56
Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell (2002) 4.38
Whole-genome analysis of histone H3 lysine 27 trimethylation in Arabidopsis. PLoS Biol (2007) 4.30
Assessing validity of ICD-9-CM and ICD-10 administrative data in recording clinical conditions in a unique dually coded database. Health Serv Res (2008) 4.25
Prolinks: a database of protein functional linkages derived from coevolution. Genome Biol (2004) 4.07
Mediator requirement for both recruitment and postrecruitment steps in transcription initiation. Mol Cell (2005) 3.46
Risk of COPD from exposure to biomass smoke: a metaanalysis. Chest (2010) 3.46
Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3. Hepatology (2015) 3.10
Respiratory uncoupling lowers blood pressure through a leptin-dependent mechanism in genetically obese mice. Arterioscler Thromb Vasc Biol (2002) 3.01
Requirement of Hos2 histone deacetylase for gene activity in yeast. Science (2002) 2.95
Acetyl-CoA induces cell growth and proliferation by promoting the acetylation of histones at growth genes. Mol Cell (2011) 2.88
Macrophage Wnt7b is critical for kidney repair and regeneration. Proc Natl Acad Sci U S A (2010) 2.87
MSL complex is attracted to genes marked by H3K36 trimethylation using a sequence-independent mechanism. Mol Cell (2007) 2.87
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana. Genome Biol (2009) 2.86
Scm3 is essential to recruit the histone h3 variant cse4 to centromeres and to maintain a functional kinetochore. Mol Cell (2007) 2.82
RSC exploits histone acetylation to abrogate the nucleosomal block to RNA polymerase II elongation. Mol Cell (2006) 2.77
SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity. Cancer Cell (2011) 2.73
The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators. Cell (2005) 2.71
Genome-wide association of histone H3 lysine nine methylation with CHG DNA methylation in Arabidopsis thaliana. PLoS One (2008) 2.69
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers. AIDS (2008) 2.67
X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations. Proc Natl Acad Sci U S A (2008) 2.53
Adenovirus small e1a alters global patterns of histone modification. Science (2008) 2.43
The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation. Nat Cell Biol (2012) 2.41
Readers of histone modifications. Cell Res (2011) 2.40
Epigenetic reprogramming by adenovirus e1a. Science (2008) 2.38
Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit. Science (2002) 2.33
Analysis of the adenovirus E1B-55K-anchored proteome reveals its link to ubiquitination machinery. J Virol (2002) 2.31
Escape from autologous neutralizing antibodies in acute/early subtype C HIV-1 infection requires multiple pathways. PLoS Pathog (2009) 2.29
Global levels of histone modifications predict prognosis in different cancers. Am J Pathol (2009) 2.28
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II. Mol Cell (2004) 2.27
Phosphorylated Pol II CTD recruits multiple HDACs, including Rpd3C(S), for methylation-dependent deacetylation of ORF nucleosomes. Mol Cell (2010) 2.26
p31comet blocks Mad2 activation through structural mimicry. Cell (2007) 2.26
Association of EGFR mutation or ALK rearrangement with expression of DNA repair and synthesis genes in never-smoker women with pulmonary adenocarcinoma. Cancer (2012) 2.24
Cse4 is part of an octameric nucleosome in budding yeast. Mol Cell (2009) 2.23
Enhancement of synaptic plasticity through chronically reduced Ca2+ flux during uncorrelated activity. Neuron (2004) 2.21
An epidemiologic survey of pediatric sepsis in regional hospitals in China. Pediatr Crit Care Med (2014) 2.16
Inference of protein function and protein linkages in Mycobacterium tuberculosis based on prokaryotic genome organization: a combined computational approach. Genome Biol (2003) 2.04
Comparison and calibration of transcriptome data from RNA-Seq and tiling arrays. BMC Genomics (2010) 2.03
Three acyltransferases and nitrogen-responsive regulator are implicated in nitrogen starvation-induced triacylglycerol accumulation in Chlamydomonas. J Biol Chem (2012) 2.03
MORC family ATPases required for heterochromatin condensation and gene silencing. Science (2012) 1.97
The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes. J Biol Chem (2005) 1.93
ATAC is a double histone acetyltransferase complex that stimulates nucleosome sliding. Nat Struct Mol Biol (2008) 1.90
Transmembrane glycine zippers: physiological and pathological roles in membrane proteins. Proc Natl Acad Sci U S A (2005) 1.90
Genome resequencing reveals multiscale geographic structure and extensive linkage disequilibrium in the forest tree Populus trichocarpa. New Phytol (2012) 1.88
Role of neuronal energy status in the regulation of adenosine 5'-monophosphate-activated protein kinase, orexigenic neuropeptides expression, and feeding behavior. Endocrinology (2004) 1.87
Molecular recognition by a binary code. J Mol Biol (2005) 1.85
ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. Nat Struct Mol Biol (2009) 1.85
RNA-seq analysis of sulfur-deprived Chlamydomonas cells reveals aspects of acclimation critical for cell survival. Plant Cell (2010) 1.83
Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell (2010) 1.81
In and out: histone variant exchange in chromatin. Trends Biochem Sci (2005) 1.81
An artificial somatic-autonomic reflex pathway procedure for bladder control in children with spina bifida. J Urol (2005) 1.78
Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli. Mol Syst Biol (2010) 1.75
Systems biology approach in Chlamydomonas reveals connections between copper nutrition and multiple metabolic steps. Plant Cell (2011) 1.74
An artificial somatic-central nervous system-autonomic reflex pathway for controllable micturition after spinal cord injury: preliminary results in 15 patients. J Urol (2003) 1.73
Mice expressing a humanized form of VEGF-A may provide insights into the safety and efficacy of anti-VEGF antibodies. Proc Natl Acad Sci U S A (2007) 1.73
DNA methylation dynamics, metabolic fluxes, gene splicing, and alternative phenotypes in honey bees. Proc Natl Acad Sci U S A (2012) 1.65
BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data. BMC Genomics (2013) 1.64
Depletion of CD4⁺ T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques. J Clin Invest (2011) 1.62
Mutants of Mucor hiemalis endo-beta-N-acetylglucosaminidase show enhanced transglycosylation and glycosynthase-like activities. J Biol Chem (2007) 1.62
Cellular histone modification patterns predict prognosis and treatment response in resectable pancreatic adenocarcinoma: results from RTOG 9704. J Clin Oncol (2010) 1.57
Unraveling inflammatory responses using systems genetics and gene-environment interactions in macrophages. Cell (2012) 1.57
The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila melanogaster X chromosome. Nat Struct Mol Biol (2008) 1.55
Evolution of an expanded sex-determining locus in Volvox. Science (2010) 1.55
Genomics: protein fossils live on as RNA. Nature (2008) 1.54
IL-23 promotes CD4+ T cells to produce IL-17 in Vogt-Koyanagi-Harada disease. J Allergy Clin Immunol (2007) 1.54
Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions. J Mol Biol (2004) 1.53
A comparative analysis of DNA methylation across human embryonic stem cell lines. Genome Biol (2011) 1.52
Clinical characteristics of Vogt-Koyanagi-Harada syndrome in Chinese patients. Ophthalmology (2006) 1.52
SAS-mediated acetylation of histone H4 Lys 16 is required for H2A.Z incorporation at subtelomeric regions in Saccharomyces cerevisiae. Genes Dev (2006) 1.51
Follow-through after calling a nurse telephone advice line: a population-based study. Fam Pract (2010) 1.50
The B cell response is redundant and highly focused on V1V2 during early subtype C infection in a Zambian seroconverter. J Virol (2010) 1.49
Abnormal anterior cingulum in patients with schizophrenia: a diffusion tensor imaging study. Neuroreport (2003) 1.49
A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo. PLoS Pathog (2010) 1.48
A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome Res (2013) 1.48
Plants regenerated from tissue culture contain stable epigenome changes in rice. Elife (2013) 1.48
SWI/SNF-dependent chromatin remodeling of RNR3 requires TAF(II)s and the general transcription machinery. Genes Dev (2003) 1.47
Two-year outcome of high-risk benign prostate hyperplasia patients treated with transurethral prostate resection by plasmakinetic or conventional procedure. Urology (2012) 1.47
Perioperative approach in the surgical management of carotid body tumors. Ann Vasc Surg (2012) 1.47
Adenovirus exploits the cellular aggresome response to accelerate inactivation of the MRN complex. J Virol (2005) 1.46
Genomewide clonal analysis of lethal mutations in the Drosophila melanogaster eye: comparison of the X chromosome and autosomes. Genetics (2007) 1.44
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation. Retrovirology (2015) 1.43
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium. Cell (2012) 1.43