Published in Nature on August 16, 2012
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Derivation of novel human ground state naive pluripotent stem cells. Nature (2013) 5.90
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The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell (2012) 4.32
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Release of severe acute respiratory syndrome coronavirus nuclear import block enhances host transcription in human lung cells. J Virol (2013) 1.08
UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. Cancer Res (2014) 1.08
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Cell reprogramming requires silencing of a core subset of polycomb targets. PLoS Genet (2013) 0.95
Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming. Genes Dev (2015) 0.95
KDM6 demethylase independent loss of histone H3 lysine 27 trimethylation during early embryonic development. PLoS Genet (2014) 0.95
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Molecular features of cellular reprogramming and development. Nat Rev Mol Cell Biol (2016) 0.93
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Transitions between epithelial and mesenchymal states during cell fate conversions. Protein Cell (2014) 0.87
UTX coordinates steroid hormone-mediated autophagy and cell death. Nat Commun (2013) 0.87
Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche. Development (2013) 0.86
Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep (2015) 0.86
UTX demethylase activity is required for satellite cell-mediated muscle regeneration. J Clin Invest (2016) 0.85
UTX inhibits EMT-induced breast CSC properties by epigenetic repression of EMT genes in cooperation with LSD1 and HDAC1. EMBO Rep (2015) 0.85
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JMJD3 as an epigenetic regulator in development and disease. Int J Biochem Cell Biol (2015) 0.85
Chemical approaches to cell reprogramming. Curr Opin Genet Dev (2014) 0.85
The use of small molecules in somatic-cell reprogramming. Trends Cell Biol (2013) 0.85
Genetic and Epigenetic Mechanisms That Maintain Hematopoietic Stem Cell Function. Stem Cells Int (2015) 0.84
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Generation of human iPSCs from cells of fibroblastic and epithelial origin by means of the oriP/EBNA-1 episomal reprogramming system. Stem Cell Res Ther (2015) 0.84
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Understanding impediments to cellular conversion to pluripotency by assessing the earliest events in ectopic transcription factor binding to the genome. Cell Cycle (2013) 0.83
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Histone demethylases in chromatin biology and beyond. EMBO Rep (2015) 0.81
Histone demethylases in physiology and cancer: a tale of two enzymes, JMJD3 and UTX. Curr Opin Genet Dev (2016) 0.81
Chromatin dynamics during plant sexual reproduction. Front Plant Sci (2014) 0.80
SALL4, the missing link between stem cells, development and cancer. Gene (2016) 0.80
An essential role for UTX in resolution and activation of bivalent promoters. Nucleic Acids Res (2016) 0.80
Polycomb determines responses to smad2/3 signaling in embryonic stem cell differentiation and in reprogramming. Stem Cells (2013) 0.79
The dosage of Patz1 modulates reprogramming process. Sci Rep (2014) 0.79
H3K27 demethylase, JMJD3, regulates fragmentation of spermatogonial cysts. PLoS One (2013) 0.79
Re-patterning of H3K27me3, H3K4me3 and DNA methylation during fibroblast conversion into induced cardiomyocytes. Stem Cell Res (2016) 0.79
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Gadd45a is a heterochromatin relaxer that enhances iPS cell generation. EMBO Rep (2016) 0.77
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Pleiotropic Functions of H3K27Me3 Demethylases in Immune Cell Differentiation. Trends Immunol (2016) 0.76
Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors. PLoS One (2015) 0.76
DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection. Oncogene (2016) 0.75
Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms. Mol Cell Biol (2016) 0.75
The Maternal Effect Genes UTX and JMJD3 Play Contrasting Roles in Mus musculus Preimplantation Embryo Development. Sci Rep (2016) 0.75
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Mechanisms underlying the formation of induced pluripotent stem cells. Wiley Interdiscip Rev Dev Biol (2015) 0.75
Chromatin changes in reprogramming of mammalian somatic cells. Rejuvenation Res (2014) 0.75
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nat Immunol (2016) 0.75
Increasing Notch signaling antagonizes PRC2-mediated silencing to promote reprograming of germ cells into neurons. Elife (2016) 0.75
A rapid passage through a two-active-X-chromosome state accompanies the switch of imprinted X-inactivation patterns in mouse trophoblast stem cells. Epigenetics Chromatin (2015) 0.75
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Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program. Proc Natl Acad Sci U S A (2016) 0.75
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Knockdown of Brm and Baf170, Components of Chromatin Remodeling Complex, Facilitates Reprogramming of Somatic Cells. Stem Cells Dev (2015) 0.75
Pluripotent cells will not dosage compensate. Worm (2014) 0.75
The EP300, KDM5A, KDM6A and KDM6B chromatin regulators cooperate with KLF4 in the transcriptional activation of POU5F1. PLoS One (2012) 0.75
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Model-based analysis of ChIP-Seq (MACS). Genome Biol (2008) 51.63
Integrative genomics viewer. Nat Biotechnol (2011) 42.83
Core transcriptional regulatory circuitry in human embryonic stem cells. Cell (2005) 34.93
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
Dissecting direct reprogramming through integrative genomic analysis. Nature (2008) 16.47
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
New cell lines from mouse epiblast share defining features with human embryonic stem cells. Nature (2007) 13.54
Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. Cell Stem Cell (2008) 12.45
Derivation of pluripotent epiblast stem cells from mammalian embryos. Nature (2007) 11.72
Direct cell reprogramming is a stochastic process amenable to acceleration. Nature (2009) 8.71
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature (2007) 8.32
Role of the murine reprogramming factors in the induction of pluripotency. Cell (2009) 7.46
Nanog is the gateway to the pluripotent ground state. Cell (2009) 7.27
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05
A histone H3 lysine 27 demethylase regulates animal posterior development. Nature (2007) 6.57
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells. Cell (2011) 6.22
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing. Cell (2007) 6.07
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A model for transmission of the H3K27me3 epigenetic mark. Nat Cell Biol (2008) 5.55
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The murine polycomb group protein Eed is required for global histone H3 lysine-27 methylation. Curr Biol (2005) 4.52
Chromatin-modifying enzymes as modulators of reprogramming. Nature (2012) 4.22
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Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci U S A (2004) 3.39
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UTX, a histone H3-lysine 27 demethylase, acts as a critical switch to activate the cardiac developmental program. Dev Cell (2011) 1.66
Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state. Development (2010) 1.58
A PiggyBac-based recessive screening method to identify pluripotency regulators. PLoS One (2011) 1.30
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Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science (2009) 29.83
A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell (2010) 12.27
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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development. Nature (2007) 8.32
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A histone H3 lysine 27 demethylase regulates animal posterior development. Nature (2007) 6.57
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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells. Cell (2011) 3.20
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