Published in Eur J Immunol on June 01, 2010
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Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science (2010) 5.84
Early origin and recent expansion of Plasmodium falciparum. Science (2003) 4.07
Intraluminal crawling of neutrophils to emigration sites: a molecularly distinct process from adhesion in the recruitment cascade. J Exp Med (2006) 3.38
Infection-induced NETosis is a dynamic process involving neutrophil multitasking in vivo. Nat Med (2012) 3.38
A novel mechanism of rapid nuclear neutrophil extracellular trap formation in response to Staphylococcus aureus. J Immunol (2010) 3.20
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Endothelium-derived Toll-like receptor-4 is the key molecule in LPS-induced neutrophil sequestration into lungs. J Clin Invest (2003) 2.89
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils. Nat Immunol (2008) 2.88
The neutrophil in vascular inflammation. Nat Med (2011) 2.84
Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity. Nat Med (2011) 2.82
Enhanced S-nitroso-albumin formation from inhaled NO during ischemia/reperfusion. Circ Res (2004) 2.75
Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors. J Virol (2002) 2.55
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs. Nat Genet (2010) 2.48
An intracellular signaling hierarchy determines direction of migration in opposing chemotactic gradients. J Cell Biol (2002) 2.48
Functional innervation of hepatic iNKT cells is immunosuppressive following stroke. Science (2011) 2.44
Platelets express functional Toll-like receptor-4. Blood (2005) 2.37
A new genetic subgroup of chronic granulomatous disease with autosomal recessive mutations in p40 phox and selective defects in neutrophil NADPH oxidase activity. Blood (2009) 2.35
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TNF-alpha-secreting monocytes are recruited into the brain of cholestatic mice. Hepatology (2006) 2.23
Impaired cytoadherence of Plasmodium falciparum-infected erythrocytes containing sickle hemoglobin. Proc Natl Acad Sci U S A (2008) 2.19
Intravascular neutrophil extracellular traps capture bacteria from the bloodstream during sepsis. Cell Host Microbe (2012) 2.17
Abnormal display of PfEMP-1 on erythrocytes carrying haemoglobin C may protect against malaria. Nature (2005) 2.17
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The inflammasomes in kidney disease. J Am Soc Nephrol (2011) 2.09
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis. Nat Med (2012) 2.08
The NLRP3 inflammasome promotes renal inflammation and contributes to CKD. J Am Soc Nephrol (2010) 2.04
An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells. Nat Immunol (2010) 2.03
Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis. J Clin Invest (2013) 2.03
Platelets contribute to the pathogenesis of experimental autoimmune encephalomyelitis. Circ Res (2012) 1.85
The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β. Exp Physiol (2012) 1.85
Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids. J Exp Med (2008) 1.84
The physiology of leukocyte recruitment: an in vivo perspective. J Immunol (2008) 1.84
Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome. Gastroenterology (2010) 1.83
Immune surveillance by the liver. Nat Immunol (2013) 1.79
LSP1 is an endothelial gatekeeper of leukocyte transendothelial migration. J Exp Med (2005) 1.72
Mice that exclusively express TLR4 on endothelial cells can efficiently clear a lethal systemic Gram-negative bacterial infection. J Clin Invest (2009) 1.70
TLR4 contributes to disease-inducing mechanisms resulting in central nervous system autoimmune disease. J Immunol (2004) 1.70
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain. J Clin Invest (2010) 1.67
Immune surveillance in the central nervous system. Nat Neurosci (2012) 1.63
IVIg therapy in brain inflammation: etiology-dependent differential effects on leucocyte recruitment. Brain (2004) 1.61
Targeting adhesion molecules as a potential mechanism of action for intravenous immunoglobulin. Circulation (2005) 1.60
Intravascular immunity: the host-pathogen encounter in blood vessels. Nat Rev Immunol (2009) 1.60
Toll gates and traffic arteries: from endothelial TLR2 to atherosclerosis. Circ Res (2004) 1.59
Real-time high resolution 3D imaging of the lyme disease spirochete adhering to and escaping from the vasculature of a living host. PLoS Pathog (2008) 1.59
The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver. Blood (2011) 1.56
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP. J Cell Sci (2008) 1.54
Endothelial paxillin and focal adhesion kinase (FAK) play a critical role in neutrophil transmigration. Eur J Immunol (2012) 1.53
Role of CD44 and hyaluronan in neutrophil recruitment. J Immunol (2004) 1.53
Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay. Sci STKE (2003) 1.50
Essential role for neutrophil recruitment to the liver in concanavalin A-induced hepatitis. J Immunol (2004) 1.49
A requirement for microglial TLR4 in leukocyte recruitment into brain in response to lipopolysaccharide. J Immunol (2006) 1.49
Nucleation of platelets with blood-borne pathogens on Kupffer cells precedes other innate immunity and contributes to bacterial clearance. Nat Immunol (2013) 1.46
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Leukocyte migration is regulated by L-selectin endoproteolytic release. Immunity (2003) 1.42
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Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection. Nat Immunol (2013) 1.37
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Immune cell Toll-like receptor 4 is required for cardiac myocyte impairment during endotoxemia. Circ Res (2004) 1.35
Depletion of Ly6G/Gr-1 leukocytes after spinal cord injury in mice alters wound healing and worsens neurological outcome. J Neurosci (2009) 1.35
Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog (2008) 1.34
The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol (2006) 1.34
Activation of p38 and ERK signaling during adenovirus vector cell entry lead to expression of the C-X-C chemokine IP-10. J Virol (2002) 1.34
Neutrophils recruited to sites of infection protect from virus challenge by releasing neutrophil extracellular traps. Cell Host Microbe (2013) 1.33
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Neutrophils promote liver metastasis via Mac-1-mediated interactions with circulating tumor cells. Cancer Res (2012) 1.30
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Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome. Nat Med (2009) 1.29
Adenovirus vector-induced inflammation: capsid-dependent induction of the C-C chemokine RANTES requires NF-kappa B. Hum Gene Ther (2002) 1.27
Overlapping roles of P-selectin and alpha 4 integrin to recruit leukocytes to the central nervous system in experimental autoimmune encephalomyelitis. J Immunol (2002) 1.25
CD34 facilitates the development of allergic asthma. Blood (2007) 1.25
Chemokines: sirens of neutrophil recruitment-but is it just one song? Immunity (2010) 1.24
Anti-adhesive effect of nitric oxide on Plasmodium falciparum cytoadherence under flow. Am J Pathol (2003) 1.23
Role of endothelial TLR4 for neutrophil recruitment into central nervous system microvessels in systemic inflammation. J Immunol (2009) 1.23
Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1. Immunity (2005) 1.23
Vav1 is essential for mechanotactic crawling and migration of neutrophils out of the inflamed microvasculature. J Immunol (2009) 1.23
Antibodies against neutrophil LY6G do not inhibit leukocyte recruitment in mice in vivo. Blood (2013) 1.23
Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium. J Immunol (2012) 1.22
Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow. J Exp Med (2013) 1.21
Macrophages eliminate circulating tumor cells after monoclonal antibody therapy. J Clin Invest (2014) 1.21
Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2. J Neurosci (2008) 1.20
Neutrophil elastase acts as a biased agonist for proteinase-activated receptor-2 (PAR2). J Biol Chem (2011) 1.19
The use of spinning-disk confocal microscopy for the intravital analysis of platelet dynamics in response to systemic and local inflammation. PLoS One (2011) 1.17
Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo. Blood (2010) 1.15
Cytotoxic CD4+ T cells use granulysin to kill Cryptococcus neoformans, and activation of this pathway is defective in HIV patients. Blood (2006) 1.15
Fundamentally different roles for LFA-1, Mac-1 and alpha4-integrin in neutrophil chemotaxis. J Cell Sci (2005) 1.15
The innate immune response to DNA. Semin Immunol (2009) 1.14
Leukocyte adhesion in the liver: distinct adhesion paradigm from other organs. J Hepatol (2007) 1.12
Complement is an essential component of the immune response to adeno-associated virus vectors. J Virol (2008) 1.11
Molecular regulators of leucocyte chemotaxis during inflammation. Cardiovasc Res (2010) 1.11