Published in Mol Syst Biol on January 01, 2012
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Regulatory changes underlying expression differences within and between Drosophila species. Nat Genet (2008) 3.24
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RNA polymerase II subunits link transcription and mRNA decay to translation. Cell (2010) 2.67
Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective. PLoS Genet (2012) 2.57
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Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation. Mol Syst Biol (2008) 2.27
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Protein quantification across hundreds of experimental conditions. Proc Natl Acad Sci U S A (2009) 1.10
Paternally biased X inactivation in mouse neonatal brain. Genome Biol (2010) 1.03
Computational analysis of whole-genome differential allelic expression data in human. PLoS Comput Biol (2010) 0.99
Accurate proteome-wide protein quantification from high-resolution 15N mass spectra. Genome Biol (2011) 0.87
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Genetic dissection of transcriptional regulation in budding yeast. Science (2002) 25.01
Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet (2003) 21.52
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Mapping complex disease loci in whole-genome association studies. Nature (2004) 7.31
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Genetic interactions between polymorphisms that affect gene expression in yeast. Nature (2005) 6.42
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays. BMC Genomics (2009) 6.41
Genetic structure of the purebred domestic dog. Science (2004) 6.39
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Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biol (2005) 5.61
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Additional SNPs and linkage-disequilibrium analyses are necessary for whole-genome association studies in humans. Nat Genet (2003) 5.30
Stable suppression of gene expression by RNAi in mammalian cells. Proc Natl Acad Sci U S A (2002) 5.05
Gene-environment interaction in yeast gene expression. PLoS Biol (2008) 4.48
Natural malaria infection in Anopheles gambiae is regulated by a single genomic control region. Science (2006) 4.38
Dissection of genetically complex traits with extremely large pools of yeast segregants. Nature (2010) 4.32
Haplotype diversity across 100 candidate genes for inflammation, lipid metabolism, and blood pressure regulation in two populations. Am J Hum Genet (2004) 3.91
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Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae. Nature (2009) 3.67
The meningococcal vaccine candidate GNA1870 binds the complement regulatory protein factor H and enhances serum resistance. J Immunol (2006) 3.62
Exclusion of a luminous red giant as a companion star to the progenitor of supernova SN 2011fe. Nature (2011) 3.62
Finding the sources of missing heritability in a yeast cross. Nature (2013) 3.43
Predicting functionally important residues from sequence conservation. Bioinformatics (2007) 3.42
Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray. Science (2006) 3.32
Supernova SN 2011fe from an exploding carbon-oxygen white dwarf star. Nature (2011) 3.29
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Metabolomic analysis via reversed-phase ion-pairing liquid chromatography coupled to a stand alone orbitrap mass spectrometer. Anal Chem (2010) 3.22
Recombinational landscape and population genomics of Caenorhabditis elegans. PLoS Genet (2009) 3.14
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Extensive and breed-specific linkage disequilibrium in Canis familiaris. Genome Res (2004) 2.85
Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity. Nat Genet (2012) 2.85
Widespread genetic incompatibility in C. elegans maintained by balancing selection. Science (2008) 2.84
Selection at linked sites shapes heritable phenotypic variation in C. elegans. Science (2010) 2.84
Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure. PLoS Comput Biol (2009) 2.82
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Mol Cell (2003) 2.78
Simultaneous genotyping, gene-expression measurement, and detection of allele-specific expression with oligonucleotide arrays. Genome Res (2005) 2.66
Population genomic analysis of outcrossing and recombination in yeast. Nat Genet (2006) 2.50
Quantitative mapping of a digenic behavioral trait implicates globin variation in C. elegans sensory behaviors. Neuron (2009) 2.44
Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast. PLoS Genet (2006) 2.36
Catecholamine receptor polymorphisms affect decision-making in C. elegans. Nature (2011) 2.32
Genetic basis of individual differences in the response to small-molecule drugs in yeast. Nat Genet (2007) 2.18
Genetic loci affecting resistance to human malaria parasites in a West African mosquito vector population. Science (2002) 2.11
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Absence of detectable arsenate in DNA from arsenate-grown GFAJ-1 cells. Science (2012) 2.03
A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans. Science (2009) 1.98
Toward the dynamic interactome: it's about time. Brief Bioinform (2010) 1.91
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis. PLoS Genet (2009) 1.90
Revealing complex traits with small molecules and naturally recombinant yeast strains. Chem Biol (2006) 1.87
Solving and analyzing side-chain positioning problems using linear and integer programming. Bioinformatics (2004) 1.87
Element 1360 and RNAi components contribute to HP1-dependent silencing of a pericentric reporter. Curr Biol (2006) 1.85
A novel sperm-delivered toxin causes late-stage embryo lethality and transmission ratio distortion in C. elegans. PLoS Biol (2011) 1.84
Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains. PLoS One (2007) 1.80
Characterization and prediction of residues determining protein functional specificity. Bioinformatics (2008) 1.80
Predicting gene function in a hierarchical context with an ensemble of classifiers. Genome Biol (2008) 1.78
Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans. Science (2012) 1.77
Predicting DNA recognition by Cys2His2 zinc finger proteins. Bioinformatics (2008) 1.74
How and when should interactome-derived clusters be used to predict functional modules and protein function? Bioinformatics (2009) 1.71
Influence of genotype and nutrition on survival and metabolism of starving yeast. Proc Natl Acad Sci U S A (2008) 1.69
Software tool for researching annotations of proteins: open-source protein annotation software with data visualization. Anal Chem (2009) 1.68
Molecular basis of the copulatory plug polymorphism in Caenorhabditis elegans. Nature (2008) 1.61
SPICi: a fast clustering algorithm for large biological networks. Bioinformatics (2010) 1.60
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Predicting cellular growth from gene expression signatures. PLoS Comput Biol (2009) 1.50
Predicting specificity in bZIP coiled-coil protein interactions. Genome Biol (2004) 1.47
G-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiae. PLoS Comput Biol (2010) 1.47
Regulatory and metabolic rewiring during laboratory evolution of ethanol tolerance in E. coli. Mol Syst Biol (2010) 1.47
No supernovae associated with two long-duration gamma-ray bursts. Nature (2006) 1.47
Evolution of amino acid frequencies in proteins over deep time: inferred order of introduction of amino acids into the genetic code. Mol Biol Evol (2002) 1.46
Identification and dissection of a complex DNA repair sensitivity phenotype in Baker's yeast. PLoS Genet (2008) 1.45
Riboneogenesis in yeast. Cell (2011) 1.43
Comparative analysis of methods for representing and searching for transcription factor binding sites. Bioinformatics (2004) 1.41
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids. Nat Genet (2008) 1.41
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A pan-specific antibody for direct detection of protein histidine phosphorylation. Nat Chem Biol (2013) 1.40
Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics (2009) 1.38
Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol (2014) 1.34
De novo prediction of DNA-binding specificities for Cys2His2 zinc finger proteins. Nucleic Acids Res (2013) 1.28
Short hairpin activated gene silencing in mammalian cells. Methods Mol Biol (2004) 1.28
Allele frequency matching between SNPs reveals an excess of linkage disequilibrium in genic regions of the human genome. PLoS Genet (2006) 1.27
A cross-genomic approach for systematic mapping of phenotypic traits to genes. Genome Res (2004) 1.23
The Cutoff protein regulates piRNA cluster expression and piRNA production in the Drosophila germline. EMBO J (2011) 1.22
A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34. Am J Hum Genet (2002) 1.21
Regulation of hepadnavirus reverse transcription by dynamic nucleocapsid phosphorylation. J Virol (2006) 1.21
The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction. Bioinformatics (2009) 1.21
Directing experimental biology: a case study in mitochondrial biogenesis. PLoS Comput Biol (2009) 1.20
Novel genes exhibit distinct patterns of function acquisition and network integration. Genome Biol (2010) 1.19
A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays. Bioinformatics (2009) 1.16
Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue. Mol Cell Proteomics (2008) 1.14
More than the sum of its parts: a complex epistatic network underlies natural variation in thermal preference behavior in Caenorhabditis elegans. Genetics (2012) 1.14