Published in Cell Mol Life Sci on September 13, 2012
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A role for the primary cilium in Notch signaling and epidermal differentiation during skin development. Cell (2011) 1.83
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Activity-induced Notch signaling in neurons requires Arc/Arg3.1 and is essential for synaptic plasticity in hippocampal networks. Neuron (2011) 1.49
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol (2009) 1.48
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Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem (2004) 1.10
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Real-time imaging of notch activation with a luciferase complementation-based reporter. Sci Signal (2011) 1.05
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In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain. Neuroimage (2008) 1.03
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JNK1 inhibits GluR1 expression and GluR1-mediated calcium influx through phosphorylation and stabilization of Hes-1. J Neurosci (2012) 0.82
Dual-reporter assay using two secreted luciferase genes. Biotechniques (2007) 0.78
A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos. Gene Expr Patterns (2011) 0.77
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Integrated regulation of Toll-like receptor responses by Notch and interferon-gamma pathways. Immunity (2008) 2.62
Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development. J Biol Chem (2003) 2.59
Oscillatory control of factors determining multipotency and fate in mouse neural progenitors. Science (2013) 2.56
Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci (2010) 2.55
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Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet (2003) 2.42
Dclk1 distinguishes between tumor and normal stem cells in the intestine. Nat Genet (2012) 2.33
Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability. J Biol Chem (2005) 2.33
Retinal cell fate determination and bHLH factors. Semin Cell Dev Biol (2004) 2.33
The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev (2009) 2.19
Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition. Nat Neurosci (2008) 2.13
Real-time imaging of the somite segmentation clock: revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc Natl Acad Sci U S A (2006) 2.10
Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine. FEBS Lett (2003) 2.10
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Instability of Hes7 protein is crucial for the somite segmentation clock. Nat Genet (2004) 2.07
Math3 and NeuroD regulate amacrine cell fate specification in the retina. Development (2002) 2.07
Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev (2003) 1.93
High levels of Cre expression in neuronal progenitors cause defects in brain development leading to microencephaly and hydrocephaly. J Neurosci (2006) 1.89
Notch signaling via Hes1 transcription factor maintains survival of melanoblasts and melanocyte stem cells. J Cell Biol (2006) 1.86
The role of notch signaling in the development of intrahepatic bile ducts. Gastroenterology (2004) 1.81
Hes1 directly controls cell proliferation through the transcriptional repression of p27Kip1. Mol Cell Biol (2005) 1.79
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Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev (2006) 1.60
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Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev Cell (2007) 1.56
The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock. Dev Cell (2007) 1.54
HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. Blood (2002) 1.51
Regulation of retinal cell fate specification by multiple transcription factors. Brain Res (2007) 1.50
Hes genes and neurogenin regulate non-neural versus neural fate specification in the dorsal telencephalic midline. Development (2008) 1.50
Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system. Development (2006) 1.48
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity. J Cell Biol (2009) 1.48
Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas. J Clin Invest (2006) 1.48
Ultradian oscillations of Stat, Smad, and Hes1 expression in response to serum. Proc Natl Acad Sci U S A (2007) 1.47
Visualization of embryonic neural stem cells using Hes promoters in transgenic mice. Mol Cell Neurosci (2005) 1.41
The basic helix-loop-helix genes Hesr1/Hey1 and Hesr2/Hey2 regulate maintenance of neural precursor cells in the brain. J Biol Chem (2003) 1.41
FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr Biol (2008) 1.40
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Temporal regulation of Cre recombinase activity in neural stem cells. Genesis (2006) 1.36
Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification. J Biol Chem (2004) 1.34
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CCAAT/enhancer-binding protein phosphorylation biases cortical precursors to generate neurons rather than astrocytes in vivo. J Neurosci (2005) 1.26
RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity. Nat Neurosci (2007) 1.26
Hes1 and Hes5 control the progenitor pool, intermediate lobe specification, and posterior lobe formation in the pituitary development. Mol Endocrinol (2007) 1.25
Continuous neurogenesis in the adult forebrain is required for innate olfactory responses. Proc Natl Acad Sci U S A (2011) 1.24
Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol (2007) 1.19
Fbxw7-dependent degradation of Notch is required for control of "stemness" and neuronal-glial differentiation in neural stem cells. J Biol Chem (2011) 1.17
The role of Hes genes in intestinal development, homeostasis and tumor formation. Development (2012) 1.16
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Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells. Blood (2011) 1.14
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Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling. J Exp Med (2012) 1.13
MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain. Genes Cells (2012) 1.10
Ecosystem development and carbon cycle on a glacier foreland in the high Arctic, Ny-Alesund, Svalbard. J Plant Res (2005) 1.09
Hes1 regulates corneal development and the function of corneal epithelial stem/progenitor cells. Stem Cells (2008) 1.08
Maximizing functional photoreceptor differentiation from adult human retinal stem cells. Stem Cells (2010) 1.07
Ultradian oscillations in Notch signaling regulate dynamic biological events. Curr Top Dev Biol (2010) 1.07
Accelerating the tempo of the segmentation clock by reducing the number of introns in the Hes7 gene. Cell Rep (2012) 1.07
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Dynamic expression of notch signaling genes in neural stem/progenitor cells. Front Neurosci (2011) 1.06
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Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development (2012) 1.04
Notch-Hes1 pathway contributes to the cochlear prosensory formation potentially through the transcriptional down-regulation of p27Kip1. J Neurosci Res (2009) 1.03
Identification of a novel basic helix-loop-helix gene, Heslike, and its role in GABAergic neurogenesis. J Neurosci (2004) 1.02
Different types of oscillations in Notch and Fgf signaling regulate the spatiotemporal periodicity of somitogenesis. Genes Dev (2011) 1.02