Published in J Clin Invest on October 01, 2012
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The clerodane diterpene casearin J induces apoptosis of T-ALL cells through SERCA inhibition, oxidative stress, and interference with Notch1 signaling. Cell Death Dis (2016) 0.78
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Gamma secretase inhibitors enhance vincristine-induced apoptosis in T-ALL in a NOTCH-independent manner. Apoptosis (2014) 0.78
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Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia. Blood Cancer J (2014) 0.78
Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway. J Hematol Oncol (2016) 0.77
Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget (2016) 0.77
Targeting IRAK1 in T-cell acute lymphoblastic leukemia. Oncotarget (2015) 0.77
Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia (2015) 0.77
Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia. Nat Genet (2017) 0.77
Inactivation of KLF4 promotes T cell acute lymphoblastic leukemia and activates the MAP2K7 pathway. Leukemia (2016) 0.76
Notch signaling in hematopoietic cell transplantation and T cell alloimmunity. Blood Rev (2013) 0.76
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Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS One (2016) 0.76
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Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL. Oncotarget (2016) 0.76
FOXP3 can modulate TAL1 transcriptional activity through interaction with LMO2. Oncogene (2015) 0.76
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation. Proc Natl Acad Sci U S A (2016) 0.76
TRIB2 reinforces the oncogenic transcriptional program controlled by the TAL1 complex in T-cell acute lymphoblastic leukemia. Leukemia (2015) 0.76
Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia. Blood (2017) 0.75
Controlling pre-leukemic thymocyte self-renewal. PLoS Genet (2014) 0.75
The NEDD8-activating enzyme inhibitor MLN4924 induces G2 arrest and apoptosis in T-cell acute lymphoblastic leukemia. Oncotarget (2016) 0.75
miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20. Oncotarget (2016) 0.75
Increased PKCα activity by Rack1 overexpression is responsible for chemotherapy resistance in T-cell acute lymphoblastic leukemia-derived cell line. Sci Rep (2016) 0.75
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Synergistic Cytotoxic Effect of L-Asparaginase Combined with Decitabine as a Demethylating Agent in Pediatric T-ALL, with Specific Epigenetic Signature. Biomed Res Int (2016) 0.75
T-cell Acute Lymphoblastic Leukemia with del (7) (q11.2q22) and Aberrant Expression of Myeloid Markers. Int J Hematol Oncol Stem Cell Res (2013) 0.75
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Combined targeting of SET and tyrosine kinases provides an effective therapeutic approach in human T-cell acute lymphoblastic leukemia. Oncotarget (2016) 0.75
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Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia. Haematologica (2016) 0.75
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Effects of valproic acid and pioglitazone on cell cycle progression and proliferation of T-cell acute lymphoblastic leukemia Jurkat cells. Iran J Basic Med Sci (2016) 0.75
CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS. Leukemia (2016) 0.75
Speed of leukemia development and genetic diversity in xenograft models of T cell acute lymphoblastic leukemia. Oncotarget (2016) 0.75
Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL. Blood (2015) 0.75
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