Published in Mol Neurodegener on October 03, 2012
Filamin A promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons. J Biol Chem (2014) 0.81
X11/Mint genes control polarized localization of axonal membrane proteins in vivo. J Neurosci (2013) 0.78
Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. Behav Brain Res (2016) 0.76
Analyzing and Modeling the Dysfunction of Inhibitory Neurons in Alzheimer's Disease. PLoS One (2016) 0.75
Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (1991) 49.03
Alzheimer's disease is a synaptic failure. Science (2002) 13.82
APP processing and synaptic function. Neuron (2003) 8.37
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron (2005) 7.53
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science (2000) 4.14
Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo. Neuron (2008) 3.98
The anatomy of memory: an interactive overview of the parahippocampal-hippocampal network. Nat Rev Neurosci (2009) 3.22
Absence epilepsy and sinus dysrhythmia in mice lacking the pacemaker channel HCN2. EMBO J (2003) 3.02
Kindling and status epilepticus models of epilepsy: rewiring the brain. Prog Neurobiol (2004) 2.91
Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. J Comp Neurol (2004) 2.85
Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons. Neuron (2004) 2.74
Developmental febrile seizures modulate hippocampal gene expression of hyperpolarization-activated channels in an isoform- and cell-specific manner. J Neurosci (2002) 2.65
Progressive dendritic HCN channelopathy during epileptogenesis in the rat pilocarpine model of epilepsy. J Neurosci (2007) 2.34
Incidence and predictors of seizures in patients with Alzheimer's disease. Epilepsia (2006) 2.17
Properties and role of I(h) in the pacing of subthreshold oscillations in entorhinal cortex layer II neurons. J Neurophysiol (2000) 2.09
Enhanced expression of a specific hyperpolarization-activated cyclic nucleotide-gated cation channel (HCN) in surviving dentate gyrus granule cells of human and experimental epileptic hippocampus. J Neurosci (2003) 1.94
Arf and its many interactors. Curr Opin Cell Biol (2003) 1.94
HCN1 channels control resting and active integrative properties of stellate cells from layer II of the entorhinal cortex. J Neurosci (2007) 1.62
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
Mislocalization of h channel subunits underlies h channelopathy in temporal lobe epilepsy. Neurobiol Dis (2008) 1.54
Seizures and myoclonus in patients with Alzheimer's disease. Neurology (1986) 1.53
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J Biol Chem (2003) 1.52
The X11alpha protein slows cellular amyloid precursor protein processing and reduces Abeta40 and Abeta42 secretion. J Biol Chem (1998) 1.45
Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease. Am J Pathol (1991) 1.43
Dementia and adult-onset unprovoked seizures. Neurology (1996) 1.37
Regulation of amyloid beta-protein precursor by phosphorylation and protein interactions. J Biol Chem (2008) 1.35
h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy. Neurobiol Dis (2008) 1.35
Seizures in elderly patients with dementia: epidemiology and management. Drugs Aging (2003) 1.35
Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis. J Neurosci (2009) 1.31
Exploring HCN channels as novel drug targets. Nat Rev Drug Discov (2011) 1.28
The neuronal adaptor protein X11alpha reduces Abeta levels in the brains of Alzheimer's APPswe Tg2576 transgenic mice. J Biol Chem (2003) 1.27
Impaired hippocampal rhythmogenesis in a mouse model of mesial temporal lobe epilepsy. Proc Natl Acad Sci U S A (2007) 1.21
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. J Biol Chem (1999) 1.20
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J Biol Chem (2006) 1.19
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain. J Biol Chem (2008) 1.17
The X11/Mint family of adaptor proteins. Brain Res Rev (2006) 1.14
The neuronal adaptor protein X11beta reduces amyloid beta-protein levels and amyloid plaque formation in the brains of transgenic mice. J Biol Chem (2004) 1.12
Towards an integrated view of HCN channel role in epilepsy. Curr Opin Neurobiol (2011) 1.08
Decreases in HCN mRNA expression in the hippocampus after kindling and status epilepticus in adult rats. Epilepsia (2008) 1.02
Prevalence and causes of seizures at the time of diagnosis of probable Alzheimer's disease. Dement Geriatr Cogn Disord (2006) 0.99
Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease. EMBO Mol Med (2012) 0.96
Determinants of activation kinetics in mammalian hyperpolarization-activated cation channels. J Physiol (2001) 0.96
Hyperpolarization-activated, cyclic nucleotide-gated HCN2 cation channel forms a protein assembly with multiple neuronal scaffold proteins in distinct modes of protein-protein interaction. Genes Cells (2004) 0.95
Alzheimer-type tau pathology in advanced aged nonhuman primate brains harboring substantial amyloid deposition. Brain Res (2010) 0.94
X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice. Hum Mol Genet (2009) 0.91
Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like. PLoS One (2011) 0.88
Histopathological studies of senile plaques and cerebral amyloidosis in cynomolgus monkeys. J Med Primatol (1998) 0.87
Rab6 interacts with the mint3 adaptor protein. Biol Chem (2005) 0.87
Neuropathological and clinical phenotype of an Italian Alzheimer family with M239V mutation of presenilin 2 gene. J Neuropathol Exp Neurol (2004) 0.85
Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain. Mol Neurodegener (2010) 0.84
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype. J Neurosci (2008) 0.80
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration. Acta Neuropathol (2007) 8.10
Imaging cellular signals in the heart in vivo: Cardiac expression of the high-signal Ca2+ indicator GCaMP2. Proc Natl Acad Sci U S A (2006) 4.71
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
Polarized and compartment-dependent distribution of HCN1 in pyramidal cell dendrites. Nat Neurosci (2002) 2.86
Immunohistochemical localization of Ih channel subunits, HCN1-4, in the rat brain. J Comp Neurol (2004) 2.85
Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron (2006) 2.53
Metabolic control of vesicular glutamate transport and release. Neuron (2010) 2.44
Prospective 10-year surveillance of human prion diseases in Japan. Brain (2010) 2.41
Early release of HMGB-1 from neurons after the onset of brain ischemia. J Cereb Blood Flow Metab (2007) 2.31
Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proc Natl Acad Sci U S A (2010) 2.07
The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J Cell Sci (2004) 2.07
Quantitative localisation of synaptic and extrasynaptic GABAA receptor subunits on hippocampal pyramidal cells by freeze-fracture replica immunolabelling. Eur J Neurosci (2010) 2.03
Digitalis intoxication induced by paroxetine co-administration. Lancet (2006) 2.01
Mutations in EFHC1 cause juvenile myoclonic epilepsy. Nat Genet (2004) 1.98
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet (2009) 1.96
Neurogliaform neurons form a novel inhibitory network in the hippocampal CA1 area. J Neurosci (2005) 1.95
Genetically encoded bright Ca2+ probe applicable for dynamic Ca2+ imaging of dendritic spines. Anal Chem (2005) 1.91
Metabotropic glutamate receptors. Cell Tissue Res (2006) 1.89
Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. J Neurosci (2003) 1.85
Selective gating of glutamatergic inputs to excitatory neurons of amygdala by presynaptic GABAb receptor. Neuron (2009) 1.85
Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease. Hum Mol Genet (2006) 1.83
Dose-dependent effects of adjunctive treatment with aripiprazole on hyperprolactinemia induced by risperidone in female patients with schizophrenia. J Clin Psychopharmacol (2010) 1.81
Generalization of amygdala LTP and conditioned fear in the absence of presynaptic inhibition. Nat Neurosci (2006) 1.78
Asymmetrical allocation of NMDA receptor epsilon2 subunits in hippocampal circuitry. Science (2003) 1.77
Potent amyloidogenicity and pathogenicity of Aβ43. Nat Neurosci (2011) 1.76
Escherichia coli phage-shock protein A (PspA) binds to membrane phospholipids and repairs proton leakage of the damaged membranes. Mol Microbiol (2007) 1.74
Laparoscopic resection of Bismuth type I and II hilar cholangiocarcinoma: an audit of 14 cases from two institutions. Dig Surg (2011) 1.71
Granular tau oligomers as intermediates of tau filaments. Biochemistry (2007) 1.67
Cbln1 is a ligand for an orphan glutamate receptor delta2, a bidirectional synapse organizer. Science (2010) 1.65
A scaffold protein JIP-1b enhances amyloid precursor protein phosphorylation by JNK and its association with kinesin light chain 1. J Biol Chem (2003) 1.65
Accumulation of phosphorylated alpha-synuclein in aging human brain. J Neuropathol Exp Neurol (2003) 1.59
Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia. Stroke (2008) 1.58
Survival and differentiation of neural progenitor cells derived from embryonic stem cells and transplanted into ischemic brain. J Neurosurg (2005) 1.57
Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. J Neurosci Res (2005) 1.57
Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes. J Clin Invest (2016) 1.56
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J (2007) 1.55
Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. J Neurosci (2002) 1.52
Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolism. J Biol Chem (2003) 1.52
Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system. Cell Metab (2009) 1.51
Validation of cardiac (123)I-MIBG scintigraphy in patients with Parkinson's disease who were diagnosed with dopamine PET. Eur J Nucl Med Mol Imaging (2010) 1.51
Lewy body-related alpha-synucleinopathy in aging. J Neuropathol Exp Neurol (2004) 1.49
Increased levels of granular tau oligomers: an early sign of brain aging and Alzheimer's disease. Neurosci Res (2006) 1.49
Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Rep (2013) 1.49
Thermophilic ATP synthase has a decamer c-ring: indication of noninteger 10:3 H+/ATP ratio and permissive elastic coupling. Proc Natl Acad Sci U S A (2004) 1.48
HCN2 and HCN1 channels govern the regularity of autonomous pacemaking and synaptic resetting in globus pallidus neurons. J Neurosci (2004) 1.47
Effect of dose timing in relation to food intake on systemic exposure to blonanserin. Eur J Clin Pharmacol (2010) 1.47
Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J Biol Chem (2002) 1.46
Structure basis for the regulation of glyceraldehyde-3-phosphate dehydrogenase activity via the intrinsically disordered protein CP12. Structure (2011) 1.46
Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. J Neurosci (2006) 1.45
A seed for Alzheimer amyloid in the brain. J Neurosci (2004) 1.45
Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies. Ann Neurol (2003) 1.44
Utilization behavior as a white matter disconnection syndrome. Cortex (2002) 1.43
ATP-driven stepwise rotation of FoF1-ATP synthase. Proc Natl Acad Sci U S A (2005) 1.43
GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. Eur J Neurosci (2004) 1.42
Role of HCN channels in neuronal hyperexcitability after subarachnoid hemorrhage in rats. J Neurosci (2012) 1.42
A paradoxical effect of lidocaine for the N406S mutation of SCN5A associated with Brugada syndrome. Int J Cardiol (2007) 1.42
Left-right asymmetry of the hippocampal synapses with differential subunit allocation of glutamate receptors. Proc Natl Acad Sci U S A (2008) 1.42
Association between the 5-HT1A receptor gene polymorphism (rs6295) and antidepressants: a meta-analysis. Int Clin Psychopharmacol (2012) 1.42
Deferoxamine attenuates iron-induced long-term neurotoxicity in rats with traumatic brain injury. Neurol Sci (2012) 1.42
Tissue inhibitor of metalloproteinases protect blood-brain barrier disruption in focal cerebral ischemia. J Cereb Blood Flow Metab (2008) 1.41
Association between major Multidrug Resistance 1 (MDR1) gene polymorphisms and plasma concentration of prolactin during risperidone treatment in schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry (2007) 1.38
Number and density of AMPA receptors in single synapses in immature cerebellum. J Neurosci (2005) 1.37
Axle-less F1-ATPase rotates in the correct direction. Science (2008) 1.36
Muscarinic receptor activation modulates granule cell excitability and potentiates inhibition onto mitral cells in the rat olfactory bulb. J Neurosci (2007) 1.34
Distinct localization of GABA(B) receptors relative to synaptic sites in the rat cerebellum and ventrobasal thalamus. Eur J Neurosci (2002) 1.33
Latent genetic backgrounds and molecular pathogenesis in drug-induced long-QT syndrome. Circ Arrhythm Electrophysiol (2009) 1.33
Visual properties of transgenic rats harboring the channelrhodopsin-2 gene regulated by the thy-1.2 promoter. PLoS One (2009) 1.33
Crosstalk between GABAB and mGlu1a receptors reveals new insight into GPCR signal integration. EMBO J (2009) 1.32
Regulatory interplay between proton motive force, ADP, phosphate, and subunit epsilon in bacterial ATP synthase. J Biol Chem (2006) 1.32
Cell type dependence and variability in the short-term plasticity of EPSCs in identified mouse hippocampal interneurones. J Physiol (2002) 1.32
Quantitative analysis and subcellular distribution of mRNA and protein expression of the hyperpolarization-activated cyclic nucleotide-gated channels throughout development in rat hippocampus. Cereb Cortex (2006) 1.32
HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease. Nat Neurosci (2010) 1.32
Immunolocalization of metabotropic glutamate receptor 1alpha (mGluR1alpha) in distinct classes of interneuron in the CA1 region of the rat hippocampus. Hippocampus (2004) 1.32
Differential expression of calretinin and metabotropic glutamate receptor mGluR1alpha defines subsets of unipolar brush cells in mouse cerebellum. J Comp Neurol (2002) 1.31
Treatment of localised renal cell carcinoma. Eur Urol (2011) 1.29
Number and density of AMPA receptors in individual synapses in the rat cerebellum as revealed by SDS-digested freeze-fracture replica labeling. J Neurosci (2007) 1.28
High-resolution quantitative visualization of glutamate and GABA receptors at central synapses. Curr Opin Neurobiol (2007) 1.28
Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. J Biol Chem (2004) 1.26
Dynamic change of chromatin conformation in response to hypoxia enhances the expression of GLUT3 (SLC2A3) by cooperative interaction of hypoxia-inducible factor 1 and KDM3A. Mol Cell Biol (2012) 1.26
Endoplasmic reticulum chaperones inhibit the production of amyloid-beta peptides. Biochem J (2007) 1.24
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies. Acta Neuropathol (2006) 1.24
Mutations of neuronal voltage-gated Na+ channel alpha 1 subunit gene SCN1A in core severe myoclonic epilepsy in infancy (SMEI) and in borderline SMEI (SMEB). Epilepsia (2004) 1.24
Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1. J Neurosci (2008) 1.24
Neuropathology of mild cognitive impairment. Neuropathology (2007) 1.23
Staging of argyrophilic grains: an age-associated tauopathy. J Neuropathol Exp Neurol (2004) 1.23
Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor. J Cell Biol (2004) 1.22
Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med (2013) 1.22
SOD1 (copper/zinc superoxide dismutase) deficiency drives amyloid β protein oligomerization and memory loss in mouse model of Alzheimer disease. J Biol Chem (2011) 1.19
Enhanced amyloidogenic metabolism of the amyloid beta-protein precursor in the X11L-deficient mouse brain. J Biol Chem (2006) 1.19
Lewy body pathology involves cutaneous nerves. J Neuropathol Exp Neurol (2008) 1.19
Differential distribution of release-related proteins in the hippocampal CA3 area as revealed by freeze-fracture replica labeling. J Comp Neurol (2005) 1.18
X11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain. J Biol Chem (2008) 1.17
Bidirectional alterations in cerebellar synaptic transmission of tottering and rolling Ca2+ channel mutant mice. J Neurosci (2002) 1.17
Targeted disruption of the mouse ELYS gene results in embryonic death at peri-implantation development. Genes Cells (2004) 1.17
Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup. J Neurobiol (2003) 1.17