Published in Am J Physiol Renal Physiol on October 10, 2012
Traditional and emerging roles for the SLC9 Na+/H+ exchangers. Pflugers Arch (2013) 0.99
Loss of NHE1 activity leads to reduced oxidative stress in heart and mitigates high-fat diet-induced myocardial stress. J Mol Cell Cardiol (2013) 0.84
Acid-Base Homeostasis. Clin J Am Soc Nephrol (2015) 0.81
Molecular mechanisms of renal and extrarenal manifestations caused by inactivation of the electrogenic Na(+)-HCO3 (-) cotransporter NBCe1. Front Physiol (2013) 0.79
Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors. Am J Physiol Renal Physiol (2016) 0.79
Proximal tubular NHEs: sodium, protons and calcium? Am J Physiol Renal Physiol (2013) 0.79
Roles of renal proximal tubule transport in acid/base balance and blood pressure regulation. Biomed Res Int (2014) 0.78
Developmental changes in renal tubular transport-an overview. Pediatr Nephrol (2013) 0.78
Glucocorticoids Reduce Renal NHE8 Expression. Physiol Rep (2013) 0.77
Renal acid-base regulation: new insights from animal models. Pflugers Arch (2014) 0.77
Renal NHE expression and activity in neonatal NHE3- and NHE8-null mice. Am J Physiol Renal Physiol (2014) 0.75
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol (2002) 82.19
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger. Nat Genet (1998) 3.96
Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc Natl Acad Sci U S A (1998) 3.24
NHE3: a Na+/H+ exchanger isoform of renal brush border. Am J Physiol (1993) 1.93
Growth-related renal type II Na/Pi cotransporter. J Biol Chem (2002) 1.90
Heterogeneity of sodium-dependent D-glucose transport sites along the proximal tubule: evidence from vesicle studies. Am J Physiol (1982) 1.70
Cell pH in the rat proximal convoluted tubule. Regulation by luminal and peritubular pH and sodium concentration. J Clin Invest (1986) 1.68
Role of the Na+/H+ antiporter in rat proximal tubule bicarbonate absorption. J Clin Invest (1987) 1.59
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice. Am J Physiol (1999) 1.47
Sodium, bicarbonate, and chloride absorption by the proximal tubule. Am J Physiol (1983) 1.37
Mechanisms of chloride transport in the proximal tubule. Am J Physiol (1997) 1.37
Glucocorticoids acutely increase cell surface Na+/H+ exchanger-3 (NHE3) by activation of NHE3 exocytosis. Am J Physiol Renal Physiol (2005) 1.31
Role of NHE3 in mediating renal brush border Na+-H+ exchange. Adaptation to metabolic acidosis. J Biol Chem (1996) 1.30
Micropuncture analysis of single-nephron function in NHE3-deficient mice. Am J Physiol (1999) 1.30
Neonatal rabbit juxtamedullary proximal convoluted tubule acidification. J Clin Invest (1990) 1.29
Renal expression of novel Na+/H+ exchanger isoform NHE8. Am J Physiol Renal Physiol (2002) 1.28
Npt2a and Npt2c in mice play distinct and synergistic roles in inorganic phosphate metabolism and skeletal development. Am J Physiol Renal Physiol (2009) 1.28
Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics. J Physiol (2001) 1.27
Immunolocalization of NHE8 in rat kidney. Am J Physiol Renal Physiol (2004) 1.24
Prenatal programming of rat proximal tubule Na+/H+ exchanger by dexamethasone. Am J Physiol Regul Integr Comp Physiol (2006) 1.16
Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol (2007) 1.16
Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule. J Clin Invest (2000) 1.16
Gastrointestinal distribution and kinetic characterization of the sodium-hydrogen exchanger isoform 8 (NHE8). Cell Physiol Biochem (2008) 1.16
Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2. Am J Physiol Renal Physiol (2001) 1.12
Developmental changes in rabbit juxtamedullary proximal convoluted tubule acidification. Pediatr Res (1992) 1.11
Ontogeny of NHE8 in the rat proximal tubule. Am J Physiol Renal Physiol (2007) 1.10
Ontogeny of Na+/H+ antiporter activity in rat proximal convoluted tubules. Pediatr Res (2000) 1.10
Effect of thyroid hormone on the postnatal renal expression of NHE8. Am J Physiol Renal Physiol (2007) 1.00
Pendrin in the mouse kidney is primarily regulated by Cl- excretion but also by systemic metabolic acidosis. Am J Physiol Cell Physiol (2008) 1.00
Basolateral membrane Cl/HCO3 exchange in the rat proximal convoluted tubule. Na-dependent and -independent modes. J Gen Physiol (1987) 0.99
NHE2X3 DKO mice exhibit gender-specific NHE8 compensation. Am J Physiol Gastrointest Liver Physiol (2011) 0.89
Effect of metabolic acidosis on neonatal proximal tubule acidification. Am J Physiol Regul Integr Comp Physiol (2010) 0.85
Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule. Am J Physiol Renal Physiol (2001) 0.85
Unilateral ureteral obstruction alters expression of acid-base transporters in rat kidney. J Urol (2009) 0.79
The mutational landscape of head and neck squamous cell carcinoma. Science (2011) 16.88
FGF23 induces left ventricular hypertrophy. J Clin Invest (2011) 7.22
Regulation of fibroblast growth factor-23 signaling by klotho. J Biol Chem (2006) 6.50
Dupilumab in persistent asthma with elevated eosinophil levels. N Engl J Med (2013) 5.29
Randomized trial of oral teriflunomide for relapsing multiple sclerosis. N Engl J Med (2011) 4.93
Klotho deficiency causes vascular calcification in chronic kidney disease. J Am Soc Nephrol (2010) 4.59
The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors. Cancer Cell (2009) 4.47
The developmental dynamics of the maize leaf transcriptome. Nat Genet (2010) 4.02
A requirement for CARMA1 in TCR-induced NF-kappa B activation. Nat Immunol (2002) 3.38
Reference genome sequence of the model plant Setaria. Nat Biotechnol (2012) 3.21
Priming in systemic plant immunity. Science (2009) 3.11
Selection of potential markers for epithelial ovarian cancer with gene expression arrays and recursive descent partition analysis. Clin Cancer Res (2004) 2.96
Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule. FASEB J (2010) 2.91
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood (2009) 2.91
The metabolic syndrome and uric acid nephrolithiasis: novel features of renal manifestation of insulin resistance. Kidney Int (2004) 2.89
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B. J Biol Chem (2002) 2.88
The relationship of eosinophilia to intravenous immunoglobulin treatment failure in Kawasaki disease. Pediatr Allergy Immunol (2007) 2.81
In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses. Nat Biotechnol (2009) 2.76
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1. FEBS Lett (2002) 2.66
Triple versus dual antiplatelet therapy in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Circulation (2009) 2.62
Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int (2010) 2.50
Inferring reputation promotes the evolution of cooperation in spatial social dilemma games. PLoS One (2012) 2.41
A critical role of IFNgamma in priming MSC-mediated suppression of T cell proliferation through up-regulation of B7-H1. Cell Res (2008) 2.38
Nephrolithiasis-associated bone disease: pathogenesis and treatment options. Kidney Int (2010) 2.35
Potential markers that complement expression of CA125 in epithelial ovarian cancer. Gynecol Oncol (2005) 2.34
Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster. Proc Natl Acad Sci U S A (2002) 2.33
First-in-human trial of a STAT3 decoy oligonucleotide in head and neck tumors: implications for cancer therapy. Cancer Discov (2012) 2.31
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkers. Cancer Discov (2013) 2.29
Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation. Proc Natl Acad Sci U S A (2009) 2.23
Tunneling and coupled motion in the Escherichia coli dihydrofolate reductase catalysis. J Am Chem Soc (2004) 2.21
Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma. Am J Gastroenterol (2010) 2.20
Re-emerging superconductivity at 48 kelvin in iron chalcogenides. Nature (2012) 2.13
Low-molecular-weight heparin versus unfractionated heparin in acute ST-segment elevation myocardial infarction patients undergoing primary percutaneous coronary intervention with drug-eluting stents. Am Heart J (2010) 2.09
Low urine pH: a novel feature of the metabolic syndrome. Clin J Am Soc Nephrol (2007) 2.02
Effects of estrogen depletion on angiogenesis in estrogen-receptor-positive breast carcinoma--an immunohistochemical study of vasohibin-1 and CD31 with correlation to pathobiological response of the patients in neoadjuvant aromatase inhibitor therapy. Expert Opin Ther Targets (2012) 2.00
Nucleation and growth of nanoparticles in the atmosphere. Chem Rev (2011) 1.99
Targeting Stat3 abrogates EGFR inhibitor resistance in cancer. Clin Cancer Res (2012) 1.89
Hepatic resection as a safe and effective treatment for hepatocellular carcinoma involving a single large tumor, multiple tumors, or macrovascular invasion. Medicine (Baltimore) (2015) 1.88
Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats. Gastroenterology (2011) 1.85
AMPK dysregulation promotes diabetes-related reduction of superoxide and mitochondrial function. J Clin Invest (2013) 1.84
Effect of renal denervation on prenatal programming of hypertension and renal tubular transporter abundance. Am J Physiol Renal Physiol (2008) 1.82
Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet. Kidney Int (2012) 1.82
Bionanotechnology based on silica nanoparticles. Med Res Rev (2004) 1.81
Pathophysiologic basis for normouricosuric uric acid nephrolithiasis. Kidney Int (2002) 1.78
Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism. Annu Rev Physiol (2013) 1.78
Role of RhoA-specific guanine exchange factors in regulation of endomitosis in megakaryocytes. Dev Cell (2012) 1.76
Effect of high protein diet on stone-forming propensity and bone loss in rats. Kidney Int (2003) 1.76
Setaria viridis: a model for C4 photosynthesis. Plant Cell (2010) 1.72
Metabolic syndrome and the risk of calcium stones. Nephrol Dial Transplant (2012) 1.71
FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1. Am J Physiol Renal Physiol (2009) 1.70
Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI). J Biol Chem (2005) 1.68
Formation of nanoparticles of blue haze enhanced by anthropogenic pollution. Proc Natl Acad Sci U S A (2009) 1.67
Effect of fibroblast growth factor-23 on phosphate transport in proximal tubules. Kidney Int (2005) 1.67
Albumin regulates the Na+/H+ exchanger 3 in OKP cells. J Am Soc Nephrol (2003) 1.67
CARD-8 protein, a new CARD family member that regulates caspase-1 activation and apoptosis. J Biol Chem (2002) 1.66
Urine composition in type 2 diabetes: predisposition to uric acid nephrolithiasis. J Am Soc Nephrol (2006) 1.66
Decompressive hemicraniectomy in malignant middle cerebral artery infarct: a randomized controlled trial enrolling patients up to 80 years old. Neurocrit Care (2012) 1.65
DelPhi: a comprehensive suite for DelPhi software and associated resources. BMC Biophys (2012) 1.64
Correlation of pandemic (H1N1) 2009 viral load with disease severity and prolonged viral shedding in children. Emerg Infect Dis (2010) 1.64
Risk of MDM2 SNP309 alone or in combination with the p53 codon 72 polymorphism in acute myeloid leukemia. Leuk Res (2009) 1.64
Klotho: a novel regulator of calcium and phosphorus homeostasis. Pflugers Arch (2011) 1.63
Idiopathic bilateral optic atrophy in the rhesus macaque. Invest Ophthalmol Vis Sci (2005) 1.62
Molecular surveillance of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi by genotyping and subtyping parasites in wastewater. PLoS Negl Trop Dis (2012) 1.60
High-affinity peptide against MT1-MMP for in vivo tumor imaging. J Control Release (2011) 1.59
Comparison of insulin action on glucose versus potassium uptake in humans. Clin J Am Soc Nephrol (2011) 1.57
Antipurinergic therapy corrects the autism-like features in the poly(IC) mouse model. PLoS One (2013) 1.56
Cloning and characterization of the human soluble adenylyl cyclase. Am J Physiol Cell Physiol (2005) 1.54
Hypercalciuria associated with high dietary protein intake is not due to acid load. J Clin Endocrinol Metab (2011) 1.54
Aberrant expression of TSC2 gene in the newly diagnosed acute leukemia. Leuk Res (2009) 1.52
Circadian variation in urine pH and uric acid nephrolithiasis risk. Nephrol Dial Transplant (2007) 1.51
High-responsivity graphene/InAs nanowire heterojunction near-infrared photodetectors with distinct photocurrent on/off ratios. Small (2014) 1.49
Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol (2013) 1.49
Etiological role of estrogen status in renal stone formation. J Urol (2002) 1.48
Tourniquet device for hemorrhage control during cesarean section of complete placenta previa pregnancies. J Obstet Gynaecol Res (2013) 1.48
Toll-like receptor 9 activation of signal transducer and activator of transcription 3 constrains its agonist-based immunotherapy. Cancer Res (2009) 1.46
Long-term combined treatment with thiazide and potassium citrate in nephrolithiasis does not lead to hypokalemia or hypochloremic metabolic alkalosis. Kidney Int (2003) 1.46
Therapeutic potential of adipose-derived stem cells-based micro-tissues in a rat model of postprostatectomy erectile dysfunction. J Sex Med (2014) 1.44
Energy dependence of response of new high sensitivity radiochromic films for megavoltage and kilovoltage radiation energies. Med Phys (2005) 1.44
Defining hypercalciuria in nephrolithiasis. Kidney Int (2011) 1.44
BCL-xL is a target gene regulated by hypoxia-inducible factor-1{alpha}. J Biol Chem (2009) 1.43
Rare cell isolation and analysis in microfluidics. Lab Chip (2014) 1.42
Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells. J Biol Chem (2010) 1.42
Placement of 125I implants with the da Vinci robotic system after video-assisted thoracoscopic wedge resection: a feasibility study. Int J Radiat Oncol Biol Phys (2004) 1.42
Metabolic basis for low urine pH in type 2 diabetes. Clin J Am Soc Nephrol (2010) 1.41
Requirement of Gab2 for mast cell development and KitL/c-Kit signaling. Blood (2002) 1.41
Induction of interleukin 2 expression in the liver for the treatment of H22 hepatoma in mice. Dig Liver Dis (2012) 1.41
Structure of the acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1. Nat Commun (2012) 1.41
Renal ammonium excretion after an acute acid load: blunted response in uric acid stone formers but not in patients with type 2 diabetes. Am J Physiol Renal Physiol (2013) 1.40
Prevalence and spot urine risk factors for renal stones in children taking topiramate. J Pediatr Urol (2013) 1.39
DHA supplemented in peptamen diet offers no advantage in pathways to amyloidosis: is it time to evaluate composite lipid diet? PLoS One (2011) 1.39
Multidisciplinary optimization of a butterfly valve. ISA Trans (2009) 1.39
HMBG1 mediates ischemia-reperfusion injury by TRIF-adaptor independent Toll-like receptor 4 signaling. J Cereb Blood Flow Metab (2010) 1.39
Induction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancer. J Clin Oncol (2010) 1.37
Toll-like receptor 4 involvement in hepatic ischemia/reperfusion injury in mice. Hepatobiliary Pancreat Dis Int (2004) 1.37
Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers. Cancer Res (2003) 1.35
An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci U S A (2006) 1.35
Dual biological effects of the cytokines interleukin-10 and interferon-γ. Cancer Immunol Immunother (2011) 1.34