Published in J Diabetes Metab on June 23, 2012
Type 2 Diabetes Risk Allele Loci in the Qatari Population. PLoS One (2016) 1.38
Sixty-five common genetic variants and prediction of type 2 diabetes. Diabetes (2014) 1.21
Genome-wide association study identifies two novel Loci with sex-specific effects for type 2 diabetes mellitus and glycemic traits in a korean population. Diabetes Metab J (2014) 1.04
Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. Am J Hum Genet (2014) 0.94
Risk factors contributing to type 2 diabetes and recent advances in the treatment and prevention. Int J Med Sci (2014) 0.91
Introduction to personalized medicine in diabetes mellitus. Rambam Maimonides Med J (2014) 0.85
Linking obesity with type 2 diabetes: the role of T-bet. Diabetes Metab Syndr Obes (2014) 0.81
Association of common genetic variants with diabetes and metabolic syndrome related traits in the Arizona Insulin Resistance registry: a focus on Mexican American families in the Southwest. Hum Hered (2014) 0.81
Intrauterine Growth Retardation - A Developmental Model of Type 2 Diabetes. Drug Discov Today Dis Models (2013) 0.80
FOXN3 Regulates Hepatic Glucose Utilization. Cell Rep (2016) 0.80
Association of APOE polymorphisms with diabetes and cardiometabolic risk factors and the role of APOE genotypes in response to anti-diabetic therapy: results from the AIDHS/SDS on a South Asian population. J Diabetes Complications (2015) 0.79
Contiguous mutation syndrome in the era of high-throughput sequencing. Mol Genet Genomic Med (2015) 0.78
CNV Analysis Associates AKNAD1 with Type-2 Diabetes in Jordan Subpopulations. Sci Rep (2015) 0.77
Association of DPP4 Gene Polymorphisms with Type 2 Diabetes Mellitus in Malaysian Subjects. PLoS One (2016) 0.77
Linkage of type 2 diabetes on chromosome 9p24 in Mexican Americans: additional evidence from the Veterans Administration Genetic Epidemiology Study (VAGES). Hum Hered (2013) 0.77
Complex disease interventions from a network model for type 2 diabetes. PLoS One (2013) 0.77
Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population. PLoS One (2016) 0.76
MAP3K1 May be a Promising Susceptibility Gene for Type 2 Diabetes Mellitus in an Iranian Population. Int J Mol Cell Med (2016) 0.75
Type 2 Diabetes Susceptibility in the Greek-Cypriot Population: Replication of Associations with TCF7L2, FTO, HHEX, SLC30A8 and IGF2BP2 Polymorphisms. Genes (Basel) (2017) 0.75
Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype. Genom Data (2015) 0.75
Integrated genomic and BMI analysis for type 2 diabetes risk assessment. Front Genet (2015) 0.75
A New Method to Assess Asymmetry in Fingerprints Could Be Used as an Early Indicator of Type 2 Diabetes Mellitus. J Diabetes Sci Technol (2016) 0.75
Expression of JAZF1, ABCC8, KCNJ11and Notch2 genes and vitamin D receptor polymorphisms in type 2 diabetes, and their association with microvascular complications. Ther Adv Endocrinol Metab (2017) 0.75
RNA-seq analysis of the kidneys of broiler chickens fed diets containing different concentrations of calcium. Sci Rep (2017) 0.75
Association between 28 single nucleotide polymorphisms and type 2 diabetes mellitus in the Kazakh population: a case-control study. BMC Med Genet (2017) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med (2002) 101.79
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med (2001) 56.11
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A (2009) 54.68
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health. Obes Res (1998) 50.73
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature (2007) 35.08
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. Science (2007) 32.97
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Genetic dissection of complex traits. Science (1994) 29.54
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract (2009) 25.83
Are rare variants responsible for susceptibility to complex diseases? Am J Hum Genet (2001) 22.46
Multiple rare alleles contribute to low plasma levels of HDL cholesterol. Science (2004) 21.65
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet (2007) 19.04
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet (2006) 19.03
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
On the allelic spectrum of human disease. Trends Genet (2001) 16.26
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet (2006) 15.14
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet (2009) 15.00
The continuing epidemics of obesity and diabetes in the United States. JAMA (2001) 14.84
Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet (2008) 13.95
Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL. Nat Genet (2007) 13.78
Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"? Am J Hum Genet (1962) 13.72
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet (2007) 13.28
Type 2 (non-insulin-dependent) diabetes mellitus: the thrifty phenotype hypothesis. Diabetologia (1992) 13.20
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Genotype, haplotype and copy-number variation in worldwide human populations. Nature (2008) 12.40
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study. N Engl J Med (2007) 12.24
Rare independent mutations in renal salt handling genes contribute to blood pressure variation. Nat Genet (2008) 11.80
The spread of the obesity epidemic in the United States, 1991-1998. JAMA (1999) 11.52
Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet (1991) 11.30
Environmental epigenomics and disease susceptibility. Nat Rev Genet (2007) 11.02
The new genomics: global views of biology. Science (1996) 10.77
Insulin-promoter-factor 1 is required for pancreas development in mice. Nature (1994) 10.13
The allelic architecture of human disease genes: common disease-common variant...or not? Hum Mol Genet (2002) 10.08
Uncovering the roles of rare variants in common disease through whole-genome sequencing. Nat Rev Genet (2010) 9.53
Charting a course for genomic medicine from base pairs to bedside. Nature (2011) 9.39
Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus. Nat Genet (2008) 9.39
Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia (1993) 8.86
Clinical risk factors, DNA variants, and the development of type 2 diabetes. N Engl J Med (2008) 8.70
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet (2008) 7.54
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33
Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr (2000) 6.82
Increasing prevalence of the metabolic syndrome among u.s. Adults. Diabetes Care (2004) 6.68
The origins of the developmental origins theory. J Intern Med (2007) 6.03
Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev (1997) 5.66
Genomics, type 2 diabetes, and obesity. N Engl J Med (2010) 5.58
Structural variation in the human genome. N Engl J Med (2007) 5.52
A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet (2008) 5.49
Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia (1992) 5.25
beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes. Genes Dev (1998) 5.25
Prospective study of major dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr (2000) 5.17
Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes Res Clin Pract (2010) 5.16
Meta-analysis of the influence of I148M variant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease. Hepatology (2011) 5.10
Diabetes in identical twins. A study of 200 pairs. Diabetologia (1981) 5.02
Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion. Nat Genet (2008) 4.84
The Human Genome Project: lessons from large-scale biology. Science (2003) 4.69
Genome-wide association studies in diverse populations. Nat Rev Genet (2010) 4.68
Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am J Hum Genet (1990) 4.54
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action. J Clin Invest (2007) 4.47
Pathogenesis of type 2 diabetes mellitus. Med Clin North Am (2004) 4.44
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet (2010) 4.42
A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels. Science (2008) 4.38
AMPK: an emerging drug target for diabetes and the metabolic syndrome. Cell Metab (2009) 4.30
Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles. Cell (1997) 4.20
Genomics for the world. Nature (2011) 3.68
Coronary heart disease and its risk factors in first-generation immigrant Asian Indians to the United States of America. Indian Heart J (1996) 3.66
Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas. Proc Natl Acad Sci U S A (2004) 3.62
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci. Nat Genet (2011) 3.46
Projecting the future diabetes population size and related costs for the U.S. Diabetes Care (2009) 3.34
Red meat consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis. Am J Clin Nutr (2011) 3.27
Deep common ancestry of indian and western-Eurasian mitochondrial DNA lineages. Curr Biol (1999) 3.06
Diabetes, hyperinsulinaemia, and coronary risk factors in Bangladeshis in east London. Br Heart J (1988) 3.05
Cross-sectional evaluation of the Finnish Diabetes Risk Score: a tool to identify undetected type 2 diabetes, abnormal glucose tolerance and metabolic syndrome. Diab Vasc Dis Res (2005) 2.91
Plasma lipoproteins: genetic influences and clinical implications. Nat Rev Genet (2009) 2.80
How to assess physical activity? How to assess physical fitness? Eur J Cardiovasc Prev Rehabil (2005) 2.78
The emerging genetic architecture of type 2 diabetes. Cell Metab (2008) 2.77
AMPK: a key regulator of energy balance in the single cell and the whole organism. Int J Obes (Lond) (2008) 2.77
Cardiovascular disease risk factors among older black, Mexican-American, and white women and men: an analysis of NHANES III, 1988-1994. Third National Health and Nutrition Examination Survey. J Am Geriatr Soc (2001) 2.70
Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care (2008) 2.66
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC Med Genet (2008) 2.63
Prevalence of diabetes in a predominantly Asian community: preliminary findings of the Coventry diabetes study. BMJ (1989) 2.54
On the use of variance per genotype as a tool to identify quantitative trait interaction effects: a report from the Women's Genome Health Study. PLoS Genet (2010) 2.48
Concordance for type 2 (non-insulin-dependent) diabetes mellitus in male twins. Diabetologia (1987) 2.44
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
Diabetes Risk Calculator: a simple tool for detecting undiagnosed diabetes and pre-diabetes. Diabetes Care (2007) 2.22
Association of acanthosis nigricans with hyperinsulinemia compared with other selected risk factors for type 2 diabetes in Cherokee Indians: the Cherokee Diabetes Study. Diabetes Care (2002) 1.37
Proteinuric nephropathy in acquired and congenital generalized lipodystrophy: baseline characteristics and course during recombinant leptin therapy. J Clin Endocrinol Metab (2004) 1.01
Vascular health in children and adolescents: effects of obesity and diabetes. Vasc Health Risk Manag (2009) 1.00
Partial defect in the cholesterol side-chain cleavage enzyme P450scc (CYP11A1) resembling nonclassic congenital lipoid adrenal hyperplasia. J Clin Endocrinol Metab (2010) 0.92
Two new unrelated cases of hereditary 1,25-dihydroxyvitamin D-resistant rickets with alopecia resulting from the same novel nonsense mutation in the vitamin D receptor gene. J Pediatr Endocrinol Metab (2010) 0.89
Type 2 diabetes and impaired fasting glucose in American Indians aged 5-40 years: the Cherokee diabetes study. Ann Epidemiol (2004) 0.87
Sex differences in cardiovascular disease risk in adolescents with type 1 diabetes. Gend Med (2012) 0.86
Ring chromosome 9 [r(9)(p24q34)]: a report of two cases. Am J Med Genet A (2005) 0.85
Prolongation of growth by treatment of 11-hydroxylase deficiency with depot-leuprolide, growth hormone, and hydrocortisone. J Pediatr Endocrinol Metab (2006) 0.83
Fatal malignant hyperthermia-like syndrome with rhabdomyolysis complicating the presentation of diabetes mellitus in adolescent males. Pediatrics (2003) 0.80
Impact of type 1 diabetes and body weight status on cardiovascular risk factors in adolescent children. J Clin Hypertens (Greenwich) (2010) 0.80
Vitamin D Deficiency and Cardio-Metabolic Risk in a North Indian Community with Highly Prevalent Type 2 Diabetes. J Diabetes Metab (2012) 0.80
Childhood obesity: epidemiology, comorbid conditions, psychological ramifications, and clinical recommendations. J Okla State Med Assoc (2004) 0.77
A Case of 36-Year-Old Woman With Recurrent Hypoglycemia Due to Insulinoma With Cytokeratin-19 Expression: A Marker of Poor Prognosis. Pancreas (2016) 0.75
Ethnic differences in fasting glucose, insulin resistance and lipid profiles in obese adolescents. J Okla State Med Assoc (2006) 0.75
Expanding metabolic screening of newborns: can the health care industry do better than public health? J Okla State Med Assoc (2003) 0.75
Early childhood nutrition in an American Indian community: educational strategy for obesity prevention. J Okla State Med Assoc (2014) 0.75
Vitamin D Status, Gender Differences, and Cardiometabolic Health Disparities. Ann Nutr Metab (2017) 0.75