Published in Genesis on September 02, 2013
Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects. J Biol Chem (2014) 0.88
Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in mice. Endocrinology (2014) 0.84
All Hormone-Producing Cell Types of the Pituitary Intermediate and Anterior Lobes Derive From Prop1-Expressing Progenitors. Endocrinology (2016) 0.79
Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage. Mol Cell Endocrinol (2015) 0.79
Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development. Mol Endocrinol (2015) 0.77
Genetically engineered mouse models of pituitary tumors. Front Oncol (2014) 0.77
Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet (1999) 55.63
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
A global double-fluorescent Cre reporter mouse. Genesis (2007) 17.86
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA. Genomics (2001) 15.03
Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev (1991) 13.28
Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A (1997) 8.35
Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell (2009) 3.53
Codon-improved Cre recombinase (iCre) expression in the mouse. Genesis (2002) 2.92
The human beta-globin gene contains multiple regulatory regions: identification of one promoter and two downstream enhancers. EMBO J (1988) 2.54
In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem (1994) 1.95
Pathohistological classification of pituitary tumors: 10 years of experience with the German Pituitary Tumor Registry. Eur J Endocrinol (2007) 1.45
Pitx1 and Pitx2 are required for development of hindlimb buds. Development (2003) 1.43
Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes. Transgenic Res (2009) 1.43
Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol (2006) 1.27
Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol Endocrinol (1994) 1.20
Targeted ablation of pituitary gonadotropes in transgenic mice. Mol Endocrinol (1991) 1.10
Birthdating studies reshape models for pituitary gland cell specification. Dev Biol (2011) 1.10
ERK signaling in the pituitary is required for female but not male fertility. Mol Endocrinol (2009) 1.09
Cre-mediated recombination in the pituitary gland. Genesis (2001) 1.09
Large-insert BAC/YAC libraries for selective re-isolation of genomic regions by homologous recombination in yeast. Genomics (2001) 1.05
Related pituitary cell lineages develop into interdigitated 3D cell networks. Proc Natl Acad Sci U S A (2011) 1.04
Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol (1998) 1.00
Transcriptional control of precursor proliferation in the early phases of pituitary development. Curr Opin Genet Dev (2004) 0.97
Targeted ablation of cells in the pituitary primordia of transgenic mice. Mol Endocrinol (1996) 0.87
Multipotential pituitary cells that contain adrenocorticotropin (ACTH) and other pituitary hormones. Trends Endocrinol Metab (2008) 0.87
Ontogeny of plurihormonal cells in the anterior pituitary of the mouse, as studied by means of hormone mRNA detection in single cells. J Neuroendocrinol (2002) 0.80
Endothelial and perivascular cells maintain haematopoietic stem cells. Nature (2012) 6.60
Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol (2005) 4.79
Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell (2007) 4.18
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature (2010) 3.93
Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute. Development (2004) 2.54
Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. Hum Mol Genet (2003) 2.36
SnoRNA Snord116 (Pwcr1/MBII-85) deletion causes growth deficiency and hyperphagia in mice. PLoS One (2008) 2.27
Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice. Nature (2003) 2.22
Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs. J Cell Biol (2009) 1.99
Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci (2004) 1.92
To knockout in 129 or in C57BL/6: that is the question. Trends Genet (2004) 1.76
An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem J (2012) 1.71
Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line. Mamm Genome (2007) 1.68
RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis. Dev Cell (2010) 1.57
Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues. Dev Dyn (2006) 1.54
Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proc Natl Acad Sci U S A (2002) 1.52
Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele. Mol Cell Biol (2006) 1.51
Pitx2 is required at multiple stages of pituitary organogenesis: pituitary primordium formation and cell specification. Development (2002) 1.45
Role of PROP1 in pituitary gland growth. Mol Endocrinol (2004) 1.44
Pitx1 and Pitx2 are required for development of hindlimb buds. Development (2003) 1.43
Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes. Transgenic Res (2009) 1.43
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning. J Clin Invest (2012) 1.41
Regulation of the rat follicle-stimulating hormone beta-subunit promoter by activin. Mol Endocrinol (2002) 1.38
Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion. J Biol Chem (2009) 1.37
Advances in transgenic rat production. Transgenic Res (2006) 1.36
PITX genes are required for cell survival and Lhx3 activation. Mol Endocrinol (2005) 1.35
Polo-like kinase 1 is essential for early embryonic development and tumor suppression. Mol Cell Biol (2008) 1.29
Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol (2006) 1.27
FOXL2 in the pituitary: molecular, genetic, and developmental analysis. Mol Endocrinol (2006) 1.27
Gata2 is required for HSC generation and survival. J Exp Med (2013) 1.26
Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice. Hum Mol Genet (2004) 1.26
Lhx4 and Prop1 are required for cell survival and expansion of the pituitary primordia. Development (2002) 1.26
TCF and Groucho-related genes influence pituitary growth and development. Mol Endocrinol (2003) 1.24
TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol (2007) 1.22
WNT5A signaling affects pituitary gland shape. Mech Dev (2004) 1.21
Hes1 is required for pituitary growth and melanotrope specification. Dev Biol (2006) 1.20
Aurora A is essential for early embryonic development and tumor suppression. J Biol Chem (2008) 1.17
Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function. Endocrinology (2008) 1.17
RBX1/ROC1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27. Proc Natl Acad Sci U S A (2009) 1.16
PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol (2004) 1.15
Cell proliferation and vascularization in mouse models of pituitary hormone deficiency. Mol Endocrinol (2006) 1.15
Pitx2 distinguishes subtypes of terminally differentiated neurons in the developing mouse neuroepithelium. Dev Biol (2002) 1.13
SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation. Dev Cell (2011) 1.13
WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn (2008) 1.11
Birthdating studies reshape models for pituitary gland cell specification. Dev Biol (2011) 1.10
Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol (2007) 1.07
Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition. J Clin Invest (2011) 1.07
Deafness and permanently reduced potassium channel gene expression and function in hypothyroid Pit1dw mutants. J Neurosci (2009) 1.04
Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles. Mol Cell Biol (2003) 1.03
Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein. Genesis (2007) 1.03
Noggin regulates Bmp4 activity during pituitary induction. Dev Biol (2007) 1.03
Myo15 function is distinct from Myo6, Myo7a and pirouette genes in development of cochlear stereocilia. Hum Mol Genet (2003) 1.02
Dietary thyroid hormone replacement ameliorates hearing deficits in hypothyroid mice. Mamm Genome (2007) 1.02
Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol (2006) 1.01
Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics (2009) 1.01
Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells. J Clin Invest (2015) 1.00
Targeted disruption of Adamts16 gene in a rat genetic model of hypertension. Proc Natl Acad Sci U S A (2012) 1.00
A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells. Transgenic Res (2007) 1.00
Pituitary stem cell update and potential implications for treating hypopituitarism. Endocr Rev (2011) 0.99
Rederivation of transgenic and gene-targeted mice by embryo transfer. Transgenic Res (2004) 0.98
Pitx2 deletion in pituitary gonadotropes is compatible with gonadal development, puberty, and fertility. Genesis (2008) 0.94
Whirler mutant hair cells have less severe pathology than shaker 2 or double mutants. J Assoc Res Otolaryngol (2007) 0.93
Production of the butyrylcholinesterase knockout mouse. J Mol Neurosci (2006) 0.93
Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology (2005) 0.92
A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type. Hum Mol Genet (2012) 0.92
Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci (2010) 0.91
Beta-mannosidosis mice: a model for the human lysosomal storage disease. Hum Mol Genet (2005) 0.89
Corepressors TLE1 and TLE3 interact with HESX1 and PROP1. Mol Endocrinol (2010) 0.89
Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo. Biochem J (2006) 0.89
Pituitary gland development and disease: from stem cell to hormone production. Curr Top Dev Biol (2013) 0.88
Gonadal defects and hormonal alterations in transgenic mice expressing a single chain human chorionic gonadotropin-lutropin receptor complex. J Mol Endocrinol (2005) 0.88
Comparative genomics reveals functional transcriptional control sequences in the Prop1 gene. Mamm Genome (2007) 0.87
SRA gene knockout protects against diet-induced obesity and improves glucose tolerance. J Biol Chem (2014) 0.87
Transgenic mice expressing LHX3 transcription factor isoforms in the pituitary: effects on the gonadotrope axis and sex-specific reproductive disease. J Cell Physiol (2007) 0.86
Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown. Mol Reprod Dev (2003) 0.86
Exclusion of PITX2 mutations as a major cause of CHARGE association. Am J Med Genet (2002) 0.86
Candidate genes for panhypopituitarism identified by gene expression profiling. Physiol Genomics (2011) 0.85
A rat 8 kb dentin sialoprotein-phosphophoryn (DSP-PP) promoter directs spatial and temporal LacZ activity in mouse tissues. Dev Biol (2005) 0.85
Pituitary changes in Prop1 transgenic mice: hormone producing tumors and signet-ring type gonadotropes. Acta Histochem Cytochem (2008) 0.84
Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase. Toxicol Appl Pharmacol (2004) 0.83
A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development. PLoS One (2010) 0.83
Transgene expression in neonatal mouse inner ear explants mediated by first and advanced generation adenovirus vectors. Hear Res (2002) 0.83
Two pathways for cyclooxygenase-2 protein degradation in vivo. J Biol Chem (2009) 0.83
Genetic background of Prop1(df) mutants provides remarkable protection against hypothyroidism-induced hearing impairment. J Assoc Res Otolaryngol (2011) 0.82
A modifier gene alleviates hypothyroidism-induced hearing impairment in Pou1f1dw dwarf mice. Genetics (2011) 0.81
Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells. J Immunol (2008) 0.81
Age-related changes in cochlear gene expression in normal and shaker 2 mice. J Assoc Res Otolaryngol (2006) 0.80
Release of a membrane-bound death domain by gamma-secretase processing of the p75NTR homolog NRADD. J Cell Sci (2004) 0.80