Cellular reprogramming of human peripheral blood cells.

Fast and efficient neural conversion of human hematopoietic cells. Stem Cell Reports (2014) 0.80

Assessment of the Tumorigenic Potential of Spontaneously Immortalized and hTERT-Immortalized Cultured Dental Pulp Stem Cells. Stem Cells Transl Med (2015) 0.79

Reprogramming of blood cells into induced pluripotent stem cells as a new cell source for cartilage repair. Stem Cell Res Ther (2016) 0.78

An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils. Mol Ther Methods Clin Dev (2015) 0.77

Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr. Stem Cell Reports (2015) 0.76

The Generation of Human Induced Pluripotent Stem Cells from Blood Cells: An Efficient Protocol Using Serial Plating of Reprogrammed Cells by Centrifugation. Stem Cells Int (2016) 0.76

Generation of Induced Pluripotent Stem Cells from Human Peripheral T Cells Using Sendai Virus in Feeder-free Conditions. J Vis Exp (2015) 0.75

Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors. Stem Cell Reports (2016) 0.75

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51

Induced pluripotent stem cell lines derived from human somatic cells. Science (2007) 71.50

Embryonic stem cell lines derived from human blastocysts. Science (1998) 65.53

Generation of germline-competent induced pluripotent stem cells. Nature (2007) 32.77

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells. Nat Genet (2000) 21.52

Human induced pluripotent stem cells free of vector and transgene sequences. Science (2009) 17.16

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature (2008) 16.21

Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell (2010) 15.58

Generation of mouse induced pluripotent stem cells without viral vectors. Science (2008) 15.25

Epigenetic memory in induced pluripotent stem cells. Nature (2010) 14.31

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature (2011) 13.94

Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science (2007) 12.41

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends Biotechnol (2013) 11.58

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector. Nat Biotechnol (2004) 10.60

Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat Biotechnol (2008) 10.29

Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell (2013) 9.55

Somatic coding mutations in human induced pluripotent stem cells. Nature (2011) 9.50

Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature (2009) 9.29

Transcriptional amplification in tumor cells with elevated c-Myc. Cell (2012) 8.24

Copy number variation and selection during reprogramming to pluripotency. Nature (2011) 8.24

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity. Nature (2009) 7.96

Sheep cloned by nuclear transfer from a cultured cell line. Nature (1996) 7.86

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature (2012) 7.80

Immunogenicity of induced pluripotent stem cells. Nature (2011) 7.31

Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65

iPS cells produce viable mice through tetraploid complementation. Nature (2009) 6.51

c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell (2012) 6.49

Pioneer transcription factors: establishing competence for gene expression. Genes Dev (2011) 6.01

Human embryonic stem cells derived by somatic cell nuclear transfer. Cell (2013) 5.91

Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature (2011) 5.84

HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell (2002) 5.71

Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proc Jpn Acad Ser B Phys Biol Sci (2009) 5.58

Klf4 reverts developmentally programmed restriction of ground state pluripotency. Development (2009) 5.49

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol (1999) 5.35

Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature (2011) 5.28

Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science (2013) 4.94

Generation of induced pluripotent stem cells from human blood. Blood (2009) 4.92

Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol (2011) 4.64

Inhibition of antigen processing by the internal repeat region of the Epstein-Barr virus nuclear antigen-1. Nature (1995) 4.53

Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc Natl Acad Sci U S A (2008) 4.48

A molecular roadmap of reprogramming somatic cells into iPS cells. Cell (2012) 4.41

Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell (2012) 4.28

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders. Blood (2009) 4.22

Adult mice generated from induced pluripotent stem cells. Nature (2009) 4.21

Negligible immunogenicity of terminally differentiated cells derived from induced pluripotent or embryonic stem cells. Nature (2013) 4.19

Generation of induced pluripotent stem cells from human terminally differentiated circulating T cells. Cell Stem Cell (2010) 4.03

Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell (2011) 4.02

Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A (2011) 3.93

High cleavage efficiency of a 2A peptide derived from porcine teschovirus-1 in human cell lines, zebrafish and mice. PLoS One (2011) 3.90

Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome. Cell (2012) 3.80

Efficient human iPS cell derivation by a non-integrating plasmid from blood cells with unique epigenetic and gene expression signatures. Cell Res (2011) 3.58

Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes. Stem Cells (2010) 3.53

MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res (2012) 3.53

Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. Cell Stem Cell (2011) 3.31

Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell (2012) 3.30

Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol (2011) 3.25

Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells. Nature (2012) 3.09

Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell (2010) 3.08

An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. Nat Biotechnol (2011) 3.05

Reprogramming of T cells from human peripheral blood. Cell Stem Cell (2010) 2.93

Small increases in the level of Sox2 trigger the differentiation of mouse embryonic stem cells. Stem Cells (2008) 2.93

Rapid analysis of T-cell selection in vivo using T cell-receptor retrogenic mice. Nat Methods (2006) 2.87

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc Natl Acad Sci U S A (2009) 2.86

Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell (2013) 2.71

Induction of pluripotency in mouse somatic cells with lineage specifiers. Cell (2013) 2.69

Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells (2010) 2.62

IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol Ther (2000) 2.59

Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci U S A (2011) 2.51

Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell (2013) 2.45

Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat Genet (2012) 2.35

Enhanced efficiency of generating induced pluripotent stem (iPS) cells from human somatic cells by a combination of six transcription factors. Cell Res (2008) 2.29

Lin28: primal regulator of growth and metabolism in stem cells. Cell Stem Cell (2013) 2.27

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer. Nat Genet (2006) 2.19

An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells (2013) 2.18

Background mutations in parental cells account for most of the genetic heterogeneity of induced pluripotent stem cells. Cell Stem Cell (2012) 2.11

A precarious balance: pluripotency factors as lineage specifiers. Cell Stem Cell (2011) 2.07

Klf4 organizes long-range chromosomal interactions with the oct4 locus in reprogramming and pluripotency. Cell Stem Cell (2013) 2.04

Lentiviral vectors for enhanced gene expression in human hematopoietic cells. Mol Ther (2000) 2.01

Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation. Cell Stem Cell (2013) 2.01

DNA methylation dynamics in human induced pluripotent stem cells over time. PLoS Genet (2011) 2.00

RUNX1a enhances hematopoietic lineage commitment from human embryonic stem cells and inducible pluripotent stem cells. Blood (2013) 2.00

Recent advances in lentiviral vector development and applications. Mol Ther (2010) 1.89

Lentiviral vectors with two independent internal promoters transfer high-level expression of multiple transgenes to human hematopoietic stem-progenitor cells. Mol Ther (2003) 1.87

New insights into internal ribosome entry site elements relevant for viral gene expression. J Gen Virol (2008) 1.85

Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes Dev (2011) 1.73

Historical origins of transdifferentiation and reprogramming. Cell Stem Cell (2011) 1.69

Lentiviral vector design and imaging approaches to visualize the early stages of cellular reprogramming. Mol Ther (2011) 1.69

Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells. Stem Cells (2012) 1.62

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. J Clin Invest (2008) 1.61

Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. J Biol Chem (2010) 1.59

Generation of integration-free neural progenitor cells from cells in human urine. Nat Methods (2012) 1.58

Highly efficient multicistronic lentiviral vectors with peptide 2A sequences. Hum Gene Ther (2009) 1.54

Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies. Nat Rev Mol Cell Biol (2013) 1.52

A blueprint for engineering cell fate: current technologies to reprogram cell identity. Cell Res (2013) 1.50

Butyrate promotes induced pluripotent stem cell generation. J Biol Chem (2010) 1.48

Efficient generation of human iPSCs by a synthetic self-replicative RNA. Cell Stem Cell (2013) 1.47

Radical acceleration of nuclear reprogramming by chromatin remodeling with the transactivation domain of MyoD. Stem Cells (2011) 1.46

Reprogramming of human fibroblasts to pluripotency with lineage specifiers. Cell Stem Cell (2013) 1.45

Reprogrammed cells for disease modeling and regenerative medicine. Annu Rev Med (2013) 1.45

Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs. Nucleic Acids Res (2001) 1.43