Published in Int J Mol Sci on October 14, 2013
Concern The functional role of long non-coding RNAs and epigenetics. Biol Proced Online (2014) 1.73
Bridging Links between Long Noncoding RNA HOTAIR and HPV Oncoprotein E7 in Cervical Cancer Pathogenesis. Sci Rep (2015) 0.85
Regulatory RNAs and control of epigenetic mechanisms: expectations for cognition and cognitive dysfunction. Epigenomics (2015) 0.79
Genome-wide differential expression of synaptic long noncoding RNAs in autism spectrum disorder. Transl Psychiatry (2015) 0.79
Associating schizophrenia, long non-coding RNAs and neurostructural dynamics. Front Mol Neurosci (2015) 0.77
Reciprocal regulation of long noncoding RNAs THBS4‑003 and THBS4 control migration and invasion in prostate cancer cell lines. Mol Med Rep (2016) 0.76
Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation. Front Cell Neurosci (2017) 0.75
Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci. Stroke (2016) 0.75
Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92
Alternative isoform regulation in human tissue transcriptomes. Nature (2008) 52.76
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature (2009) 35.48
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs. Cell (2007) 30.22
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature (2010) 23.55
Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression. Proc Natl Acad Sci U S A (2009) 20.66
GENCODE: the reference human genome annotation for The ENCODE Project. Genome Res (2012) 19.19
The mammalian epigenome. Cell (2007) 18.13
Long noncoding RNA as modular scaffold of histone modification complexes. Science (2010) 15.23
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression. Nature (2011) 11.59
Epigenetics in human disease and prospects for epigenetic therapy. Nature (2004) 11.46
lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature (2011) 11.31
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell (2008) 9.76
A strategy for probing the function of noncoding RNAs finds a repressor of NFAT. Science (2005) 9.25
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science (2008) 8.45
Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature (2004) 7.42
An RNA gene expressed during cortical development evolved rapidly in humans. Nature (2006) 7.23
Specific expression of long noncoding RNAs in the mouse brain. Proc Natl Acad Sci U S A (2008) 7.19
Disruption of two novel genes by a translocation co-segregating with schizophrenia. Hum Mol Genet (2000) 7.16
The genetic signatures of noncoding RNAs. PLoS Genet (2009) 6.72
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression. Nat Biotechnol (2011) 6.54
An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles. Mol Cell (2009) 6.08
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res (2011) 6.02
Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med (2008) 5.62
The product of the H19 gene may function as an RNA. Mol Cell Biol (1990) 5.61
The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol (2012) 5.60
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
Parental imprinting of the mouse H19 gene. Nature (1991) 5.13
Modulating Hox gene functions during animal body patterning. Nat Rev Genet (2005) 5.10
Mutations in SOX2 cause anophthalmia. Nat Genet (2003) 5.03
The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivator. Genes Dev (2006) 4.94
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene (2010) 4.81
Non-coding RNAs: the architects of eukaryotic complexity. EMBO Rep (2001) 4.74
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene (2012) 4.30
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum Mol Genet (2007) 4.09
Overexpression of long non-coding RNA HOTAIR predicts tumor recurrence in hepatocellular carcinoma patients following liver transplantation. Ann Surg Oncol (2011) 3.88
Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8. Nat Genet (2006) 3.87
The DISC locus in psychiatric illness. Mol Psychiatry (2007) 3.46
Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain. PLoS Genet (2009) 3.38
A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO J (2010) 3.18
The long noncoding RNA, Jpx, is a molecular switch for X chromosome inactivation. Cell (2010) 3.18
The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Curr Biol (2005) 3.15
RNAs from all categories generate retrosequences that may be exapted as novel genes or regulatory elements. Gene (1999) 2.93
Genomic imprinting at the mammalian Dlk1-Dio3 domain. Trends Genet (2008) 2.92
The imprinted H19 noncoding RNA is a primary microRNA precursor. RNA (2007) 2.91
The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r. Nat Cell Biol (2012) 2.73
Catalogues of mammalian long noncoding RNAs: modest conservation and incompleteness. Genome Biol (2009) 2.70
The Dlk1 and Gtl2 genes are linked and reciprocally imprinted. Genes Dev (2000) 2.68
MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes. FEBS Lett (2010) 2.67
RNA regulation of epigenetic processes. Bioessays (2009) 2.53
Localization of the X inactivation centre on the human X chromosome in Xq13. Nature (1991) 2.48
RNA gain-of-function in spinocerebellar ataxia type 8. PLoS Genet (2009) 2.45
Upregulation of miR-196a and HOTAIR drive malignant character in gastrointestinal stromal tumors. Cancer Res (2012) 2.45
Identification of a novel non-coding RNA, MIAT, that confers risk of myocardial infarction. J Hum Genet (2006) 2.41
Long noncoding RNAs in neuronal-glial fate specification and oligodendrocyte lineage maturation. BMC Neurosci (2010) 2.34
A long ncRNA links copy number variation to a polycomb/trithorax epigenetic switch in FSHD muscular dystrophy. Cell (2012) 2.29
An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. Hum Mol Genet (2007) 2.25
The H19 locus: role of an imprinted non-coding RNA in growth and development. Bioessays (2010) 2.23
The imprinted antisense RNA at the Igf2r locus overlaps but does not imprint Mas1. Nat Genet (2000) 2.16
Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry. Nat Neurosci (2009) 2.15
Retracted The noncoding RNA Mistral activates Hoxa6 and Hoxa7 expression and stem cell differentiation by recruiting MLL1 to chromatin. Mol Cell (2011) 2.07
RNA-Seq: a method for comprehensive transcriptome analysis. Curr Protoc Mol Biol (2010) 2.03
Identification of an imprinting control region affecting the expression of all transcripts in the Gnas cluster. Nat Genet (2006) 1.98
Neurons but not glial cells show reciprocal imprinting of sense and antisense transcripts of Ube3a. Hum Mol Genet (2003) 1.92
Understanding the role of DISC1 in psychiatric disease and during normal development. J Neurosci (2009) 1.89
Long noncoding RNAs in cell biology. Semin Cell Dev Biol (2011) 1.86
The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a. Genomics (2001) 1.78
Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control. Nat Rev Mol Cell Biol (2011) 1.66
The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res (2012) 1.66
A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One (2008) 1.57
The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing. Mol Psychiatry (2013) 1.44
Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. RNA (2009) 1.44
Antisense transcript long noncoding RNA (lncRNA) HOTAIR is transcriptionally induced by estradiol. J Mol Biol (2013) 1.41
Modulating the expression of disease genes with RNA-based therapy. PLoS Genet (2007) 1.38
Dendritic BC200 RNA in aging and in Alzheimer's disease. Proc Natl Acad Sci U S A (2007) 1.29
Inhibitory effect of naked neural BC1 RNA or BC200 RNA on eukaryotic in vitro translation systems is reversed by poly(A)-binding protein (PABP). J Mol Biol (2005) 1.29
BC200 RNA: a neural RNA polymerase III product encoded by a monomeric Alu element. Proc Natl Acad Sci U S A (1993) 1.28
Translational control by a small RNA: dendritic BC1 RNA targets the eukaryotic initiation factor 4A helicase mechanism. Mol Cell Biol (2008) 1.28
Control of RNA processing by a large non-coding RNA over-expressed in carcinomas. FEBS Lett (2011) 1.21
Ntab, a novel non-coding RNA abundantly expressed in rat brain. Neuroscience (2001) 1.14
A human imprinting centre demonstrates conserved acquisition but diverged maintenance of imprinting in a mouse model for Angelman syndrome imprinting defects. Hum Mol Genet (2005) 1.07
HELLP babies link a novel lincRNA to the trophoblast cell cycle. J Clin Invest (2012) 1.07
Nkx2.2 antisense RNA overexpression enhanced oligodendrocytic differentiation. Biochem Biophys Res Commun (2008) 1.07
New meaning in the message: noncoding RNAs and their role in retinal development. Dev Dyn (2009) 1.02
The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencing. EMBO J (2006) 1.00
Enhanced reprogramming of Xist by induced upregulation of Tsix and Dnmt3a. Stem Cells (2008) 0.97
A 1q42 deletion involving DISC1, DISC2, and TSNAX in an autism spectrum disorder. Am J Med Genet A (2009) 0.97
Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease. Physiol Genomics (2010) 0.92
As antisense RNA gets intronic. OMICS (2005) 0.92
Biomarkers for Huntington's disease: an update. Expert Opin Med Diagn (2012) 0.81
Angelman syndrome scientific symposium on the structure and function of UBE3A/E6AP. J Child Neurol (2009) 0.77
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62
Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study. Lancet Neurol (2007) 3.22
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell (2008) 2.55
Variation in MAPT is associated with cerebrospinal fluid tau levels in the presence of amyloid-beta deposition. Proc Natl Acad Sci U S A (2008) 2.44
SQSTM1 mutations in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Neurology (2012) 2.06
Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric G(i)-linked receptors. J Immunol (2002) 1.88
The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimers Dement (2011) 1.87
Heterogeneity of brain glucose metabolism in mild cognitive impairment and clinical progression to Alzheimer disease. Arch Neurol (2005) 1.82
Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease. Arch Neurol (2006) 1.79
Vascular endothelial growth factor gene variability is associated with increased risk for AD. Ann Neurol (2005) 1.66
MicroRNA and mRNA expression profile screening in multiple sclerosis patients to unravel novel pathogenic steps and identify potential biomarkers. Neurosci Lett (2011) 1.64
Autosomal dominant frontotemporal lobar degeneration due to the C9ORF72 hexanucleotide repeat expansion: late-onset psychotic clinical presentation. Biol Psychiatry (2013) 1.58
Intrathecal levels of IL-6, IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration. J Neurol (2008) 1.53
Serum MCP-1 levels are increased in mild cognitive impairment and mild Alzheimer's disease. Neurobiol Aging (2005) 1.52
An APOE haplotype associated with decreased ε4 expression increases the risk of late onset Alzheimer's disease. J Alzheimers Dis (2011) 1.45
Guidelines for uniform reporting of body fluid biomarker studies in neurologic disorders. Neurology (2014) 1.45
RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. Immunity (2004) 1.42
The cornea in Sjogren's syndrome: an in vivo confocal study. Invest Ophthalmol Vis Sci (2007) 1.42
Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation. Brain (2008) 1.38
Prolonged visual memory enhancement after direct current stimulation in Alzheimer's disease. Brain Stimul (2011) 1.34
Investigation of c9orf72 in 4 neurodegenerative disorders. Arch Neurol (2012) 1.32
Chemokines in serum and cerebrospinal fluid of Alzheimer's disease patients. Ann Neurol (2003) 1.28
Plasma levels of beta-amyloid (1-42) in Alzheimer's disease and mild cognitive impairment. Neurobiol Aging (2006) 1.23
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. J Alzheimers Dis (2010) 1.19
Childhood absence epilepsy: evolution and prognostic factors. Epilepsia (2005) 1.16
Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease. Neurobiol Aging (2005) 1.15
Expression and genetic analysis of miRNAs involved in CD4+ cell activation in patients with multiple sclerosis. Neurosci Lett (2011) 1.15
Efficacy of Souvenaid in mild Alzheimer's disease: results from a randomized, controlled trial. J Alzheimers Dis (2012) 1.11
Early onset behavioral variant frontotemporal dementia due to the C9ORF72 hexanucleotide repeat expansion: psychiatric clinical presentations. J Alzheimers Dis (2012) 1.11
Corneal involvement in rheumatoid arthritis: an in vivo confocal study. Invest Ophthalmol Vis Sci (2008) 1.09
Inclusion body myopathy and frontotemporal dementia caused by a novel VCP mutation. Neurobiol Aging (2007) 1.06
Optimal plasma progranulin cutoff value for predicting null progranulin mutations in neurodegenerative diseases: a multicenter Italian study. Neurodegener Dis (2011) 1.05
Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII. Neuropsychopharmacology (2012) 1.04
Progranulin plasma levels as potential biomarker for the identification of GRN deletion carriers. A case with atypical onset as clinical amnestic Mild Cognitive Impairment converted to Alzheimer's disease. J Neurol Sci (2009) 1.03
Disease-modifying treatments for Alzheimer's disease. Ther Adv Neurol Disord (2011) 1.03
Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients. J Neuroinflammation (2011) 1.02
MCP-1 in Alzheimer's disease patients: A-2518G polymorphism and serum levels. Neurobiol Aging (2004) 1.02
Osteopontin is increased in the cerebrospinal fluid of patients with Alzheimer's disease and its levels correlate with cognitive decline. J Alzheimers Dis (2010) 1.01
Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations. Neurobiol Aging (2011) 1.00
Rs5848 variant influences GRN mRNA levels in brain and peripheral mononuclear cells in patients with Alzheimer's disease. J Alzheimers Dis (2009) 1.00
Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII. J Immunol (2005) 1.00
Is M129V of PRNP gene associated with Alzheimer's disease? A case-control study and a meta-analysis. Neurobiol Aging (2005) 0.99
Absence of TREM2 polymorphisms in patients with Alzheimer's disease and Frontotemporal Lobar Degeneration. Neurosci Lett (2006) 0.98
Immunological patterns identifying disease course and evolution in multiple sclerosis patients. J Neuroimmunol (2005) 0.97
Production of monocyte chemoattractant protein-1 in amyotrophic lateral sclerosis. Muscle Nerve (2005) 0.97
Role of hnRNP-A1 and miR-590-3p in neuronal death: genetics and expression analysis in patients with Alzheimer disease and frontotemporal lobar degeneration. Rejuvenation Res (2011) 0.97
Phenotypic heterogeneity of the GRN Asp22fs mutation in a large Italian kindred. J Alzheimers Dis (2011) 0.97
Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. PLoS One (2010) 0.97
Non-progressive leukoencephalopathy with bilateral anterior temporal cysts: a case report and review of the literature. Brain Dev (2005) 0.97
Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis. Mult Scler (2013) 0.96
Consensus definitions and application guidelines for control groups in cerebrospinal fluid biomarker studies in multiple sclerosis. Mult Scler (2013) 0.96
MicroRNAs as active players in the pathogenesis of multiple sclerosis. Int J Mol Sci (2012) 0.96
The C9orf72 repeat expansion itself is methylated in ALS and FTLD patients. Acta Neuropathol (2015) 0.95
Multiple sclerosis: BAFF and CXCL13 in cerebrospinal fluid. Mult Scler (2011) 0.95
TREM2 regulates microglial cell activation in response to demyelination in vivo. Acta Neuropathol (2015) 0.95
Expression of the transcription factor Sp1 and its regulatory hsa-miR-29b in peripheral blood mononuclear cells from patients with Alzheimer's disease. J Alzheimers Dis (2013) 0.94
A functional variant in ERAP1 predisposes to multiple sclerosis. PLoS One (2012) 0.93