Published in Mol Cell Biol on October 01, 1985
Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation. Proc Natl Acad Sci U S A (1987) 2.20
Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters. J Virol (1986) 1.38
Biochemical properties of p60v-src mutants that induce different cell transformation parameters. J Virol (1986) 1.03
Induction of proliferation of neuroretina cells by long terminal repeat activation of the carboxy-terminal part of c-mil. Mol Cell Biol (1987) 0.94
Expression of v-src in embryonic neural retina alters cell adhesion, inhibits histogenesis, and prevents induction of glutamine synthetase. Mol Cell Biol (1991) 0.87
Expression of a molecularly cloned human c-src oncogene by using a replication-competent retroviral vector. Mol Cell Biol (1986) 0.82
Distinct and different effects of the oncogenes v-myc and v-src on avian sympathetic neurons: retroviral transfer of v-myc stimulates neuronal proliferation whereas v-src transfer enhances neuronal differentiation. J Cell Biol (1990) 0.81
Mapping by in vitro constructs of the P100gag-mil region, accounting for induction of chicken neuroretina cell proliferation. J Virol (1988) 0.79
Suppression of Rous sarcoma virus-induced tumor formation by preinfection with viruses encoding src protein with novel N termini. J Virol (1989) 0.75
Transforming gene product of Rous sarcoma virus phosphorylates tyrosine. Proc Natl Acad Sci U S A (1980) 22.30
Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature (1977) 16.32
DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA. Nature (1976) 9.81
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell (1983) 7.37
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses. J Virol (1983) 7.22
Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine. Nature (1980) 6.69
Recovery of avian sarcoma virus from tumors induced by transformation-defective mutants. J Exp Med (1977) 4.79
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1984) 3.70
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol (1985) 3.39
Neural tissues express high levels of the cellular src gene product pp60c-src. Mol Cell Biol (1983) 3.27
pp60c-src is developmentally regulated in the neural retina. Cell (1984) 3.06
Development of anti-pp60src serum with antigen produced in Escherichia coli. J Virol (1983) 2.26
pp60c-src in the developing cerebellum. Mol Cell Biol (1985) 1.90
pp60c-src Kinase is in chick and human embryonic tissues. Dev Biol (1984) 1.69
Role of p60src kinase activity in the induction of neuroretinal cell proliferation by rous sarcoma virus. J Virol (1982) 1.64
Expression of viral oncogenes in differentiating chick embryo neuroretinal cells infected with avian tumor viruses. Cold Spring Harb Symp Quant Biol (1980) 1.42
Growth stimulation of chicl embryo neuroretinal cells infected with Rous sarcoma virus: relationship to viral replication and morphological transformation. Virology (1976) 1.35
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Role of the mitogenic property and kinase activity of p60src in tumor formation by Rous sarcoma virus. J Virol (1984) 0.92
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The effects of reciprocal changes in temperature on the transformed state of cells infected with a rous sarcoma virus mutant. Virology (1971) 7.83
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity (1999) 7.78
Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus. Cell (1983) 7.37
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation. Mol Cell Biol (1984) 6.40
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science (1995) 6.28
A novel viral oncogene with structural similarity to phospholipase C. Nature (1988) 5.84
Rapid transformation of cells by Rous sarcoma virus. Proc Natl Acad Sci U S A (1969) 5.27
Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav. Mol Cell Biol (1994) 5.02
Recovery of avian sarcoma virus from tumors induced by transformation-defective mutants. J Exp Med (1977) 4.79
Crystal structure of the phosphotyrosine recognition domain SH2 of v-src complexed with tyrosine-phosphorylated peptides. Nature (1992) 4.46
Genetic recombination with avian tumor virus. Virology (1972) 4.23
Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol (1998) 4.22
Cell transformation by the viral src oncogene. Annu Rev Cell Biol (1987) 4.18
Nucleotide sequence of Fujinami sarcoma virus: evolutionary relationship of its transforming gene with transforming genes of other sarcoma viruses. Cell (1982) 4.06
An N-terminal peptide from p60src can direct myristylation and plasma membrane localization when fused to heterologous proteins. Nature (1985) 4.06
Amino terminal myristylation of the protein kinase p60src, a retroviral transforming protein. Science (1985) 3.97
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene (2001) 3.96
Characterization of protein kinase activity associated with the transforming gene product of Fujinami sarcoma virus. Cell (1980) 3.82
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest (2001) 3.79
STAT proteins: novel molecular targets for cancer drug discovery. Oncogene (2000) 3.75
Location of envelope-specific and sarcoma-specific oligonucleotides on RNA of Schmidt-Ruppin Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.73
Rous sarcoma virus variants that carry the cellular src gene instead of the viral src gene cannot transform chicken embryo fibroblasts. Proc Natl Acad Sci U S A (1984) 3.70
Binding of transforming protein, P47gag-crk, to a broad range of phosphotyrosine-containing proteins. Science (1990) 3.67
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein. Proc Natl Acad Sci U S A (1979) 3.66
Proteins of helper-dependent RSV. Virology (1971) 3.62
Transformation by Rous sarcoma virus induces a novel gene with homology to a mitogenic platelet protein. Cell (1987) 3.50
Local mutagenesis of Rous sarcoma virus: the major sites of tyrosine and serine phosphorylation of pp60src are dispensable for transformation. Cell (1983) 3.46
A cell-associated factor essential for formation of an infectious form of Rous sarcoma virus. Proc Natl Acad Sci U S A (1970) 3.43
Low level of cellular protein phosphorylation by nontransforming overproduced p60c-src. Mol Cell Biol (1985) 3.39
Recombination between viral and cellular sequences generates transforming sarcoma virus. Proc Natl Acad Sci U S A (1978) 3.38
Isolation of defective mutant of avian sarcoma virus. Proc Natl Acad Sci U S A (1973) 3.38
DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. J Virol (1982) 3.35
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A (2001) 3.29
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J Biol Chem (2001) 3.27
DNA in uninfected and virus-infected cells complementary to avian tumor virus RNA. Proc Natl Acad Sci U S A (1971) 3.25
Evidence for a transcriptional activation function of BRCA1 C-terminal region. Proc Natl Acad Sci U S A (1996) 3.18
Viral and cellular src genes contribute to the structure of recovered avian sarcoma virus transforming protein. Cell (1981) 3.12
The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc Natl Acad Sci U S A (1999) 3.10
Recovery of a new virus from apparently normal chick cells by infection with avian tumor viruses. Proc Natl Acad Sci U S A (1970) 2.99
Analysis of a functional change in membrane in the process of cell transformation by Rous sarcoma virus; alteration in the characteristics of sugar transport. Virology (1970) 2.94
Determining factor in the capacity of Rous sarcoma virus to induce tumors in mammals. Proc Natl Acad Sci U S A (1966) 2.86
Detection of avian tumor virus RNA in uninfected chicken embryo cells. J Virol (1973) 2.85
Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet (1999) 2.84
Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein. Mol Cell Biol (1986) 2.84
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol (2001) 2.81
Association of the polyomavirus middle-T antigen with c-yes protein. Nature (1987) 2.78
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 2.77
Activation of the transforming potential of p60c-src by a single amino acid change. Proc Natl Acad Sci U S A (1986) 2.70
Cellular sequences related to three new onc genes of avian sarcoma virus (fps, yes, and ros) and their expression in normal and transformed cells. J Virol (1982) 2.69
c-Abl kinase regulates the protein binding activity of c-Crk. EMBO J (1994) 2.68
Characterization of the transforming gene of Fujinami sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.68
TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. Mol Cell (1999) 2.64
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. Cell Growth Differ (1997) 2.63
A type of chick embryo cell that fails to support formation of infectious RSV. Virology (1970) 2.63
In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites. J Biol Chem (1984) 2.58
Fine structural mapping of a critical NH2-terminal region of p60src. Proc Natl Acad Sci U S A (1985) 2.53
BRCA1 regulates p53-dependent gene expression. Proc Natl Acad Sci U S A (1998) 2.50
Homology exists among the transforming sequences of avian and feline sarcoma viruses. Proc Natl Acad Sci U S A (1980) 2.50
Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity. Proc Natl Acad Sci U S A (1990) 2.48
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts. Mol Cell Biol (1993) 2.47
DNA sequence of the viral and cellular src gene of chickens. II. Comparison of the src genes of two strains of avian sarcoma virus and of the cellular homolog. J Virol (1982) 2.46
Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies. Mol Cell Biol (1988) 2.44
Transformation-defective mutants of Rous sarcoma virus with src gene deletions of varying length. J Virol (1977) 2.43
Microinjection analysis of envelope-glycoprotein messenger activities of avian leukosis viral RNAs. Proc Natl Acad Sci U S A (1977) 2.42
Processing of p60v-src to its myristylated membrane-bound form. Mol Cell Biol (1985) 2.41
Isolation and characterization of fra-2, an additional member of the fos gene family. Proc Natl Acad Sci U S A (1990) 2.40
Only membrane-associated RSV src proteins have amino-terminally bound lipid. Nature (1983) 2.37
RNA of replication-defective strains of Rous sarcoma virus. Proc Natl Acad Sci U S A (1975) 2.37
Existence and expression of tumor virus genes in chick embryo cells. Virology (1972) 2.36
Synethesis and integration of viral DNA in chicken cells at different time after infection with various multiplicities of avian oncornavirus. J Virol (1976) 2.34
Phosphatidylinositol kinase activity associates with viral p60src protein. Mol Cell Biol (1989) 2.33
N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene. Mol Cell Biol (1985) 2.32
Novel tyrosine kinase identified by phosphotyrosine antibody screening of cDNA libraries. Mol Cell Biol (1988) 2.31
Genetic variation in the RNA transcripts of endogenous virus genes in uninfected chicken cells. J Virol (1977) 2.28
Analysis of the binding of the Src homology 2 domain of Csk to tyrosine-phosphorylated proteins in the suppression and mitotic activation of c-Src. Proc Natl Acad Sci U S A (1994) 2.24
A novel SAPK/JNK kinase, MKK7, stimulated by TNFalpha and cellular stresses. EMBO J (1997) 2.22
Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation. Proc Natl Acad Sci U S A (1987) 2.20
Noninfectious RSV deficient in DNA polymerase. Virology (1971) 2.18
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system. J Biol Chem (1993) 2.17
Avian sarcoma virus UR2 encodes a transforming protein which is associated with a unique protein kinase activity. J Virol (1982) 2.14
Recombination between endogenous and exogenous RNA tumor virus genes as analyzed by nucleic acid hybridization. J Virol (1975) 2.14
Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity. Cell (1982) 2.13
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res (1999) 2.09
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene (2000) 2.06
The concentric structure of the developing gut is regulated by Sonic hedgehog derived from endodermal epithelium. Development (2000) 2.03
Stabilization and productive positioning roles of the C2 domain of PTEN tumor suppressor. Cancer Res (2000) 2.02
Penetration and intracellular release of the genomes of avian RNA tumor viruses. Virology (1972) 2.02
Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells. Cancer Res (1997) 1.97
Further studies on RSV production form transformed cells. Virology (1968) 1.97
The product of the cellular crk gene consists primarily of SH2 and SH3 regions. Cell Growth Differ (1992) 1.94
Identification of domains of the v-crk oncogene product sufficient for association with phosphotyrosine-containing proteins. Mol Cell Biol (1991) 1.92
Plaque assay for some strains of avian leukosis virus. Virology (1972) 1.87
A cellular protein is immunologically crossreactive with and functionally homologous to the Fujinami sarcoma virus transforming protein. Cell (1982) 1.86
Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells. Proc Natl Acad Sci U S A (1985) 1.83
Four proline-rich sequences of the guanine-nucleotide exchange factor C3G bind with unique specificity to the first Src homology 3 domain of Crk. J Biol Chem (1994) 1.81