Published in Gastroenterology on December 31, 2013
Sirtuins in epigenetic regulation. Chem Rev (2015) 0.88
Characterizing Factors Associated With Differences in FGF19 Blood Levels and Synthesis in Patients With Primary Bile Acid Diarrhea. Am J Gastroenterol (2016) 0.87
Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer. PLoS One (2014) 0.80
Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction. PLoS One (2015) 0.79
Isocaloric Pair-Fed High-Carbohydrate Diet Induced More Hepatic Steatosis and Inflammation than High-Fat Diet Mediated by miR-34a/SIRT1 Axis in Mice. Sci Rep (2015) 0.76
The Crosstalk between the Gut Microbiota and Mitochondria during Exercise. Front Physiol (2017) 0.76
Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid-fed mouse model of cholestasis. Hepatology (2016) 0.75
The Role of Sirt1 in Bile Acid Regulation during Calorie Restriction in Mice. PLoS One (2015) 0.75
DCo(H2)ding the metabolic functions of SIRT1 in the intestine. Gastroenterology (2014) 0.75
Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development. Curr Biol (2017) 0.75
SRT1720 Alleviates ANIT-Induced Cholestasis in a Mouse Model. Front Pharmacol (2017) 0.75
The use of sacs of everted small intestine for the study of the transference of substances from the mucosal to the serosal surface. J Physiol (1954) 12.13
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell (2006) 11.38
The Sir2 family of protein deacetylases. Annu Rev Biochem (2004) 9.28
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab (2005) 9.14
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
Nuclear receptors and lipid physiology: opening the X-files. Science (2001) 8.76
Mammalian sirtuins: biological insights and disease relevance. Annu Rev Pathol (2010) 8.55
Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine. J Biol Chem (2002) 7.74
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell (2000) 6.71
The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell (2008) 6.44
The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem (2003) 6.35
Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration. Science (2006) 5.52
Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev (2009) 5.11
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J Lipid Res (2007) 3.84
Farnesoid X receptor is essential for normal glucose homeostasis. J Clin Invest (2006) 3.44
Sirtuins as potential targets for metabolic syndrome. Nature (2006) 3.38
Prevention of cholesterol gallstone disease by FXR agonists in a mouse model. Nat Med (2004) 3.17
LXRS and FXR: the yin and yang of cholesterol and fat metabolism. Annu Rev Physiol (2006) 3.11
Endocrine functions of bile acids. EMBO J (2006) 3.03
Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet (2001) 2.73
Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis. Gastroenterology (2011) 2.67
FXR acetylation is normally dynamically regulated by p300 and SIRT1 but constitutively elevated in metabolic disease states. Cell Metab (2009) 2.27
Integrated approach for manual evaluation of peptides identified by searching protein sequence databases with tandem mass spectra. J Proteome Res (2005) 2.27
In vitro absorption of bile salts by small intestine of rats and guinea pigs. Am J Physiol (1961) 2.10
FXR, a multipurpose nuclear receptor. Trends Biochem Sci (2006) 1.85
The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis. Proc Natl Acad Sci U S A (2008) 1.83
Mechanism of tissue-specific farnesoid X receptor in suppressing the expression of genes in bile-acid synthesis in mice. Hepatology (2012) 1.77
Sirtuin 1 in lipid metabolism and obesity. Ann Med (2011) 1.65
Sir2 protein deacetylases: evidence for chemical intermediates and functions of a conserved histidine. Biochemistry (2006) 1.49
SIRT1 and energy metabolism. Acta Biochim Biophys Sin (Shanghai) (2013) 1.25
Mammalian sirtuins and energy metabolism. Int J Biol Sci (2011) 1.17
FXR: a promising target for the metabolic syndrome? Trends Pharmacol Sci (2007) 1.16
Dysfunction of organic anion transporting polypeptide 1a1 alters intestinal bacteria and bile acid metabolism in mice. PLoS One (2012) 1.00
Getting the mOST from OST: Role of organic solute transporter, OSTalpha-OSTbeta, in bile acid and steroid metabolism. Biochim Biophys Acta (2010) 0.97
Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice. Mol Cell Biol (2012) 0.94
Nuclear receptors of the enteric tract: guarding the frontier. Nutr Rev (2008) 0.88
Biochemical and structural basis for partially redundant enzymatic and transcriptional functions of DCoH and DCoH2. Biochemistry (2004) 0.86