Published in J Thorac Oncol on March 01, 2014
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A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res (2011) 3.00
Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). J Med Chem (2011) 2.97
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Colistin methanesulfonate is an inactive prodrug of colistin against Pseudomonas aeruginosa. Antimicrob Agents Chemother (2006) 2.95
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Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy. J Neurosci (2013) 2.90
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A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients. Cancer Res (2005) 2.65
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The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo. Ann Neurol (2008) 2.54
Micro-optical sectioning tomography to obtain a high-resolution atlas of the mouse brain. Science (2010) 2.47
Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem (2005) 2.47
Mutations in BRAF and KRAS converge on activation of the mitogen-activated protein kinase pathway in lung cancer mouse models. Cancer Res (2007) 2.45
Central and autonomic nervous system interaction is altered by short-term meditation. Proc Natl Acad Sci U S A (2009) 2.45
Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol (2006) 2.44
Antiretroviral therapy to prevent HIV transmission in serodiscordant couples in China (2003-11): a national observational cohort study. Lancet (2012) 2.41
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Preparation, adsorption properties, and catalytic activity of 3D porous metal-organic frameworks composed of cubic building blocks and alkali-metal ions. Angew Chem Int Ed Engl (2006) 2.35
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors. Proc Natl Acad Sci U S A (2002) 2.32
MicroRNA-21 promotes fibrosis of the kidney by silencing metabolic pathways. Sci Transl Med (2012) 2.20
Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol (2011) 2.19
Relationship between glycemic control and diabetes-related hospital costs in patients with type 1 or type 2 diabetes mellitus. J Manag Care Pharm (2010) 2.18
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood (2007) 2.18
Detecting tissue-specific regulation of alternative splicing as a qualitative change in microarray data. Nucleic Acids Res (2004) 2.17
The role of the striatum in aversive learning and aversive prediction errors. Philos Trans R Soc Lond B Biol Sci (2008) 2.17
The price of racial bias: intergroup negotiations in the ultimatum game. Psychol Sci (2013) 2.15
The peroxidase activity of mitochondrial superoxide dismutase. Free Radic Biol Med (2012) 2.14
CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression. Cancer Res (2010) 2.13
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival. Blood (2011) 2.11
Refractory hypertension: definition, prevalence, and patient characteristics. J Clin Hypertens (Greenwich) (2011) 2.11
Deregulated GSK3beta activity in colorectal cancer: its association with tumor cell survival and proliferation. Biochem Biophys Res Commun (2005) 2.08
Retrograde regulation of motoneuron differentiation by muscle beta-catenin. Nat Neurosci (2008) 2.07
Intelligent urban public transportation for accessibility dedicated to people with disabilities. Sensors (Basel) (2012) 2.06
Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Comparative studies of de novo assembly tools for next-generation sequencing technologies. Bioinformatics (2011) 2.05
Structure--activity relationships of polymyxin antibiotics. J Med Chem (2010) 2.03
Hypercholesterolemia impairs the myocardial angiogenic response in a swine model of chronic ischemia: role of endostatin and oxidative stress. Ann Thorac Surg (2006) 2.02
Effect of therapeutic exercise for hip osteoarthritis pain: results of a meta-analysis. Arthritis Rheum (2008) 2.02
What's in a smile? Maternal brain responses to infant facial cues. Pediatrics (2008) 2.02
Insulin resistance and risk of ischemic stroke among nondiabetic individuals from the northern Manhattan study. Arch Neurol (2010) 2.00
Smooth muscle cells and myofibroblasts use distinct transcriptional mechanisms for smooth muscle alpha-actin expression. Circ Res (2007) 2.00
Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J Biol Chem (2006) 1.99
The cyclin-dependent kinase inhibitor flavopiridol induces apoptosis in multiple myeloma cells through transcriptional repression and down-regulation of Mcl-1. Clin Cancer Res (2002) 1.99