Published in BioData Min on March 01, 2014
Variable selection method for the identification of epistatic models. Pac Symp Biocomput (2015) 0.96
A pilot study investigating changes in neural processing after mindfulness training in elite athletes. Front Behav Neurosci (2015) 0.78
Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios. Genet Epidemiol (2015) 0.78
First complex, then simple. BioData Min (2014) 0.75
O brave new world that has such machines in it. BioData Min (2014) 0.75
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Replicating genotype-phenotype associations. Nature (2007) 16.11
Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet (2010) 14.81
A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet (2004) 10.87
The genetic structure and history of Africans and African Americans. Science (2009) 10.65
Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions. Bioinformatics (2003) 9.91
Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res (2007) 6.57
Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity. Genet Epidemiol (2003) 6.31
Genes, environment and the value of prospective cohort studies. Nat Rev Genet (2006) 4.33
A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction. Genet Epidemiol (2007) 4.15
New genes involved in cancer identified by retroviral tagging. Nat Genet (2002) 4.14
Proteomic patterns of tumour subsets in non-small-cell lung cancer. Lancet (2003) 4.01
Global analysis of X-chromosome dosage compensation. J Biol (2006) 3.78
Genetics, statistics and human disease: analytical retooling for complexity. Trends Genet (2004) 3.35
Whole genome association study of brain-wide imaging phenotypes for identifying quantitative trait loci in MCI and AD: A study of the ADNI cohort. Neuroimage (2010) 3.27
Renin-angiotensin system gene polymorphisms and atrial fibrillation. Circulation (2004) 3.02
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat Genet (2012) 2.86
Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimers Dement (2010) 2.79
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Failure to replicate a genetic association may provide important clues about genetic architecture. PLoS One (2009) 2.72
A global view of epistasis. Nat Genet (2005) 2.71
Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35. Am J Hum Genet (2004) 2.65
Machine learning for detecting gene-gene interactions: a review. Appl Bioinformatics (2006) 2.56
Optimization of neural network architecture using genetic programming improves detection and modeling of gene-gene interactions in studies of human diseases. BMC Bioinformatics (2003) 2.47
Chapter 11: Genome-wide association studies. PLoS Comput Biol (2012) 2.46
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum Mol Genet (2003) 2.33
Brief review of regression-based and machine learning methods in genetic epidemiology: the Genetic Analysis Workshop 17 experience. Genet Epidemiol (2011) 2.25
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). Hum Genet (2012) 2.18
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst (2008) 2.15
Epigenomic enhancer profiling defines a signature of colon cancer. Science (2012) 2.15
Genetic basis for adverse events after smallpox vaccination. J Infect Dis (2008) 2.09
Concordance of multiple analytical approaches demonstrates a complex relationship between DNA repair gene SNPs, smoking and bladder cancer susceptibility. Carcinogenesis (2005) 2.08
Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry. Cancer Res (2005) 2.06
Elevated male European and female African contributions to the genomes of African American individuals. Hum Genet (2006) 1.97
An application of conditional logistic regression and multifactor dimensionality reduction for detecting gene-gene interactions on risk of myocardial infarction: the importance of model validation. BMC Bioinformatics (2004) 1.95
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res (2007) 1.91
Pathway analysis of genomic data: concepts, methods, and prospects for future development. Trends Genet (2012) 1.86
Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies. BMC Genomics (2008) 1.84
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res (2009) 1.83
Shadows of complexity: what biological networks reveal about epistasis and pleiotropy. Bioessays (2009) 1.82
Multilocus analysis of hypertension: a hierarchical approach. Hum Hered (2004) 1.82
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
Ideal discrimination of discrete clinical endpoints using multilocus genotypes. In Silico Biol (2004) 1.81
Identification of novel genetic loci for intraocular pressure: a genomewide scan of the Beaver Dam Eye Study. Arch Ophthalmol (2007) 1.79
Recurrent tissue-specific mtDNA mutations are common in humans. PLoS Genet (2013) 1.77
No-boundary thinking in bioinformatics research. BioData Min (2013) 1.76
Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS. Bioinformatics (2010) 1.76
Spatially uniform relieff (SURF) for computationally-efficient filtering of gene-gene interactions. BioData Min (2009) 1.75
Short-term prediction of mortality in patients with systemic lupus erythematosus: classification of outcomes using random forests. Arthritis Rheum (2006) 1.73
A gene expression fingerprint of C. elegans embryonic motor neurons. BMC Genomics (2005) 1.72
Exploiting the proteome to improve the genome-wide genetic analysis of epistasis in common human diseases. Hum Genet (2008) 1.72
Predictor correlation impacts machine learning algorithms: implications for genomic studies. Bioinformatics (2009) 1.69
Characterizing genetic interactions in human disease association studies using statistical epistasis networks. BMC Bioinformatics (2011) 1.68
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction. Genet Epidemiol (2009) 1.61
Gut microbial colonisation in premature neonates predicts neonatal sepsis. Arch Dis Child Fetal Neonatal Ed (2012) 1.59
The behaviour of random forest permutation-based variable importance measures under predictor correlation. BMC Bioinformatics (2010) 1.59
Accelerating epistasis analysis in human genetics with consumer graphics hardware. BMC Res Notes (2009) 1.58
Combinatorial pharmacogenetics. Nat Rev Drug Discov (2005) 1.58
Ecogeographic genetic epidemiology. Genet Epidemiol (2009) 1.57
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Single-nucleotide polymorphisms for diagnosis of salt-sensitive hypertension. Clin Chem (2006) 1.51
Individual radiosensitivity measured with lymphocytes may predict the risk of acute reaction after radiotherapy. Int J Radiat Oncol Biol Phys (2008) 1.50
Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11. Am J Hum Genet (2004) 1.49
Genomewide linkage scan for myopia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 22q12. Am J Hum Genet (2004) 1.48
Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learn Mem (2002) 1.48
Evolving hard problems: Generating human genetics datasets with a complex etiology. BioData Min (2011) 1.47
Next generation analytic tools for large scale genetic epidemiology studies of complex diseases. Genet Epidemiol (2011) 1.47
Application of Genetic Algorithms to the Discovery of Complex Models for Simulation Studies in Human Genetics. Proc Genet Evol Comput Conf (2002) 1.46
Renin-angiotensin system gene polymorphisms and coronary artery disease in a large angiographic cohort: detection of high order gene-gene interaction. Atherosclerosis (2006) 1.46
A system-level pathway-phenotype association analysis using synthetic feature random forest. Genet Epidemiol (2014) 1.46
Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol (2014) 1.45
Combined genome-wide scan for prostate cancer susceptibility genes. J Natl Cancer Inst (2004) 1.44
Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. Virology (2002) 1.44
Bladder cancer SNP panel predicts susceptibility and survival. Hum Genet (2009) 1.43
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet (2011) 1.40
GAMETES: a fast, direct algorithm for generating pure, strict, epistatic models with random architectures. BioData Min (2012) 1.40
The interaction of four genes in the inflammation pathway significantly predicts prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2005) 1.39
Problems with genome-wide association studies. Science (2007) 1.39
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Medicine (Baltimore) (2006) 1.39
Drinking-water arsenic exposure modulates gene expression in human lymphocytes from a U.S. population. Environ Health Perspect (2008) 1.39
Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage. Pharmacogenet Genomics (2005) 1.38
Colonic polyps: complementary role of computer-aided detection in CT colonography. Radiology (2002) 1.38
Picking single-nucleotide polymorphisms in forests. BMC Proc (2007) 1.36
A training-testing approach to the molecular classification of resected non-small cell lung cancer. Clin Cancer Res (2003) 1.36
Evidence for a major gene influencing risk of pancreatic cancer. Genet Epidemiol (2002) 1.36
Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus. Genome Res (2012) 1.35
Evidence for epistasis between SLC6A4 and ITGB3 in autism etiology and in the determination of platelet serotonin levels. Hum Genet (2007) 1.35
Detecting pathway-based gene-gene and gene-environment interactions in pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2008) 1.33
Genetic Programming Neural Networks: A Powerful Bioinformatics Tool for Human Genetics. Appl Soft Comput (2007) 1.33
Enabling personal genomics with an explicit test of epistasis. Pac Symp Biocomput (2010) 1.33
Construction of a large signature-tagged mini-Tn5 transposon library and its application to mutagenesis of Sinorhizobium meliloti. Appl Environ Microbiol (2006) 1.31
Penetrances of breast and ovarian cancer in a large series of families tested for BRCA1/2 mutations. Eur J Hum Genet (2004) 1.29
Cytokine expression patterns associated with systemic adverse events following smallpox immunization. J Infect Dis (2006) 1.29