Published in Genet Epidemiol on January 01, 2011
Identification of genetic association of multiple rare variants using collapsing methods. Genet Epidemiol (2011) 1.26
Evaluation of the lasso and the elastic net in genome-wide association studies. Front Genet (2013) 1.15
Regression and data mining methods for analyses of multiple rare variants in the Genetic Analysis Workshop 17 mini-exome data. Genet Epidemiol (2011) 1.11
Association screening for genes with multiple potentially rare variants: an inverse-probability weighted clustering approach. BMC Proc (2011) 1.10
Comparison of random forest and parametric imputation models for imputing missing data using MICE: a CALIBER study. Am J Epidemiol (2014) 0.98
Disease risk prediction with rare and common variants. BMC Proc (2011) 0.98
Penalized-regression-based multimarker genotype analysis of Genetic Analysis Workshop 17 data. BMC Proc (2011) 0.88
Automated grouping of action potentials of human embryonic stem cell-derived cardiomyocytes. IEEE Trans Biomed Eng (2014) 0.83
Performance of random forests and logic regression methods using mini-exome sequence data. BMC Proc (2011) 0.82
Principal components ancestry adjustment for Genetic Analysis Workshop 17 data. BMC Proc (2011) 0.82
Novel tree-based method to generate markers from rare variant data. BMC Proc (2011) 0.82
Detecting gene-gene interactions using a permutation-based random forest method. BioData Min (2016) 0.81
Combining effects from rare and common genetic variants in an exome-wide association study of sequence data. BMC Proc (2011) 0.81
Gene regulatory network inference using fused LASSO on multiple data sets. Sci Rep (2016) 0.81
Supporting Regularized Logistic Regression Privately and Efficiently. PLoS One (2016) 0.80
Quality control issues and the identification of rare functional variants with next-generation sequencing data. Genet Epidemiol (2011) 0.80
Multiple testing in high-throughput sequence data: experiences from Group 8 of Genetic Analysis Workshop 17. Genet Epidemiol (2011) 0.80
Detecting rare variant associations: methods for testing haplotypes and multiallelic genotypes. Genet Epidemiol (2011) 0.80
Identifying rare-variant associations in parent-child trios using a Gaussian support vector machine. BMC Proc (2014) 0.79
LASSO model selection with post-processing for a genome-wide association study data set. BMC Proc (2011) 0.78
Identification of functional rare variants in genome-wide association studies using stability selection based on random collapsing. BMC Proc (2011) 0.78
Resampling procedures to identify important SNPs using a consensus approach. BMC Proc (2011) 0.78
Using LASSO regression to detect predictive aggregate effects in genetic studies. BMC Proc (2011) 0.77
13C NMR metabolomic evaluation of immediate and delayed mild hypothermia in cerebrocortical slices after oxygen-glucose deprivation. Anesthesiology (2013) 0.76
Predictors of High Profit and High Deficit Outliers under SwissDRG of a Tertiary Care Center. PLoS One (2015) 0.76
Comparing high-dimensional confounder control methods for rapid cohort studies from electronic health records. J Comp Eff Res (2015) 0.75
Predicting network modules of cell cycle regulators using relative protein abundance statistics. BMC Syst Biol (2017) 0.75
Comparing machine learning and logistic regression methods for predicting hypertension using a combination of gene expression and next-generation sequencing data. BMC Proc (2016) 0.75
An algorithm for candidate sequencing in non-dystrophic skeletal muscle channelopathies. J Neurol (2013) 0.75
Genome-wide association analysis by lasso penalized logistic regression. Bioinformatics (2009) 12.21
Genetic Analysis Workshop 17 mini-exome simulation. BMC Proc (2011) 9.16
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
GeneSrF and varSelRF: a web-based tool and R package for gene selection and classification using random forest. BMC Bioinformatics (2007) 2.06
Machine learning in genome-wide association studies. Genet Epidemiol (2009) 1.68
Lessons learned from Genetic Analysis Workshop 17: transitioning from genome-wide association studies to whole-genome statistical genetic analysis. Genet Epidemiol (2011) 1.34
Multigenic modeling of complex disease by random forests. Adv Genet (2010) 1.22
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Replicating genotype-phenotype associations. Nature (2007) 16.11
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet (2012) 4.37
Genes, environment and the value of prospective cohort studies. Nat Rev Genet (2006) 4.33
New genes involved in cancer identified by retroviral tagging. Nat Genet (2002) 4.14
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease. N Engl J Med (2016) 3.88
Global analysis of X-chromosome dosage compensation. J Biol (2006) 3.78
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
Comprehension of the description of side effects in drug information leaflets: a survey of doctors, pharmacists and lawyers. Dtsch Arztebl Int (2013) 3.12
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
Germline mutations and sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk. Nat Genet (2002) 2.76
Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35. Am J Hum Genet (2004) 2.65
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. PLoS One (2008) 2.37
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum Mol Genet (2003) 2.33
Genetically determined height and coronary artery disease. N Engl J Med (2015) 2.24
SNP-based analysis of genetic substructure in the German population. Hum Hered (2006) 2.21
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG). Hum Genet (2012) 2.18
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer. J Natl Cancer Inst (2008) 2.15
Biostatistical aspects of genome-wide association studies. Biom J (2008) 2.13
Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet (2012) 2.12
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA (2009) 2.10
A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet (2009) 2.09
A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. Diabetes (2011) 2.09
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia. Am J Hum Genet (2005) 1.94
Predicting functional outcome and survival after acute ischemic stroke. J Neurol (2002) 1.92
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity. Cancer Res (2007) 1.91
Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies. BMC Genomics (2008) 1.84
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene. Clin Cancer Res (2009) 1.83
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis. Nat Genet (2013) 1.83
A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
Triple target treatment (3T) is more effective than biofeedback alone for anal incontinence: the 3T-AI study. Dis Colon Rectum (2010) 1.81
Identification of novel genetic loci for intraocular pressure: a genomewide scan of the Beaver Dam Eye Study. Arch Ophthalmol (2007) 1.79
Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet (2009) 1.77
Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet (2011) 1.77
Short-term prediction of mortality in patients with systemic lupus erythematosus: classification of outcomes using random forests. Arthritis Rheum (2006) 1.73
Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. Arterioscler Thromb Vasc Biol (2010) 1.69
Predictor correlation impacts machine learning algorithms: implications for genomic studies. Bioinformatics (2009) 1.69
Machine learning in genome-wide association studies. Genet Epidemiol (2009) 1.68
Large-scale determination of SNP allele frequencies in DNA pools using MALDI-TOF mass spectrometry. Hum Mutat (2002) 1.65
Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet (2011) 1.64
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
The behaviour of random forest permutation-based variable importance measures under predictor correlation. BMC Bioinformatics (2010) 1.59
Sonothrombolysis in acute ischemic stroke for patients ineligible for rt-PA. Neurology (2005) 1.58
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. Am J Hum Genet (2013) 1.55
Association of a genetic risk score with prevalent and incident myocardial infarction in subjects undergoing coronary angiography. Circ Cardiovasc Genet (2012) 1.54
Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor. Crit Care Med (2008) 1.53
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke (2013) 1.51
Human genetic resistance to Onchocerca volvulus: evidence for linkage to chromosome 2p from an autosome-wide scan. J Infect Dis (2008) 1.49
Attention-deficit/hyperactivity disorder in a population isolate: linkage to loci at 4q13.2, 5q33.3, 11q22, and 17p11. Am J Hum Genet (2004) 1.49
Genomewide linkage scan for myopia susceptibility loci among Ashkenazi Jewish families shows evidence of linkage on chromosome 22q12. Am J Hum Genet (2004) 1.48
Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learn Mem (2002) 1.48
A system-level pathway-phenotype association analysis using synthetic feature random forest. Genet Epidemiol (2014) 1.46
Combined genome-wide scan for prostate cancer susceptibility genes. J Natl Cancer Inst (2004) 1.44
Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. Virology (2002) 1.44
Risk estimation using probability machines. BioData Min (2014) 1.40
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Medicine (Baltimore) (2006) 1.39
Colonic polyps: complementary role of computer-aided detection in CT colonography. Radiology (2002) 1.38
Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy. PLoS Genet (2010) 1.37
Picking single-nucleotide polymorphisms in forests. BMC Proc (2007) 1.36
Evidence for a major gene influencing risk of pancreatic cancer. Genet Epidemiol (2002) 1.36
A genome-wide association study for coronary artery disease identifies a novel susceptibility locus in the major histocompatibility complex. Circ Cardiovasc Genet (2012) 1.35
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
Penetrances of breast and ovarian cancer in a large series of families tested for BRCA1/2 mutations. Eur J Hum Genet (2004) 1.29
Genomewide scan in Ashkenazi Jewish families demonstrates evidence of linkage of ocular refraction to a QTL on chromosome 1p36. Hum Genet (2006) 1.28
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet (2011) 1.26
Functional linear models for association analysis of quantitative traits. Genet Epidemiol (2013) 1.26
Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. Eur Heart J (2010) 1.25
Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians. Arthritis Rheum (2006) 1.24
Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet (2013) 1.24
Genetic regulation of serum phytosterol levels and risk of coronary artery disease. Circ Cardiovasc Genet (2010) 1.23
Segregation analysis of urothelial cell carcinoma. Eur J Cancer (2006) 1.21
Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis. Arthritis Rheum (2009) 1.21
Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics. Hum Mol Genet (2007) 1.20
The clinical phenotypes of the juvenile idiopathic inflammatory myopathies. Medicine (Baltimore) (2013) 1.19
TNF polymorphisms in psoriasis: association of psoriatic arthritis with the promoter polymorphism TNF*-857 independent of the PSORS1 risk allele. Arthritis Rheum (2007) 1.19
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians. Medicine (Baltimore) (2005) 1.18
Admixture mapping of obesity-related traits in African Americans: the Atherosclerosis Risk in Communities (ARIC) Study. Obesity (Silver Spring) (2009) 1.17
Confirmation of linkage to ocular refraction on chromosome 22q and identification of a novel linkage region on 1q. Arch Ophthalmol (2007) 1.16