Published in BMC Bioinformatics on February 27, 2010
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
Data mining in the Life Sciences with Random Forest: a walk in the park or lost in the jungle? Brief Bioinform (2012) 2.00
Random forests for genomic data analysis. Genomics (2012) 1.98
An AUC-based permutation variable importance measure for random forests. BMC Bioinformatics (2013) 1.07
Letter to the editor: on the stability and ranking of predictors from random forest variable importance measures. Brief Bioinform (2011) 1.04
PhenoLink--a web-tool for linking phenotype to ~omics data for bacteria: application to gene-trait matching for Lactobacillus plantarum strains. BMC Genomics (2012) 1.02
r2VIM: A new variable selection method for random forests in genome-wide association studies. BioData Min (2016) 1.01
Risk estimation and risk prediction using machine-learning methods. Hum Genet (2012) 0.98
Variable selection method for the identification of epistatic models. Pac Symp Biocomput (2015) 0.96
Evidence for CRHR1 in multiple sclerosis using supervised machine learning and meta-analysis in 12,566 individuals. Hum Mol Genet (2010) 0.93
Exploiting SNP correlations within random forest for genome-wide association studies. PLoS One (2014) 0.89
Integrative analysis using module-guided random forests reveals correlated genetic factors related to mouse weight. PLoS Comput Biol (2013) 0.89
Splitting random forest (SRF) for determining compact sets of genes that distinguish between cancer subtypes. J Clin Bioinforma (2012) 0.86
The use of classification trees for bioinformatics. Wiley Interdiscip Rev Data Min Knowl Discov (2011) 0.85
Predicting phenotypes of asthma and eczema with machine learning. BMC Med Genomics (2014) 0.82
Influence of hydrological regime and land cover on traits and potential export capacity of adult aquatic insects from river channels. Oecologia (2015) 0.81
Correction for population stratification in random forest analysis. Int J Epidemiol (2012) 0.79
Combining techniques for screening and evaluating interaction terms on high-dimensional time-to-event data. BMC Bioinformatics (2014) 0.78
Different Statistical Approaches to Investigate Porcine Muscle Metabolome Profiles to Highlight New Biomarkers for Pork Quality Assessment. PLoS One (2016) 0.76
A methodology for exploring biomarker--phenotype associations: application to flow cytometry data and systemic sclerosis clinical manifestations. BMC Bioinformatics (2015) 0.76
Large-Scale Examination of Spatio-Temporal Patterns of Drifting Fish Aggregating Devices (dFADs) from Tropical Tuna Fisheries of the Indian and Atlantic Oceans. PLoS One (2015) 0.75
Intervention in prediction measure: a new approach to assessing variable importance for random forests. BMC Bioinformatics (2017) 0.75
Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects. Neurobiol Aging (2013) 0.75
Assessing Weather-Yield Relationships in Rice at Local Scale Using Data Mining Approaches. PLoS One (2016) 0.75
Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study. Schizophr Res (2016) 0.75
Machine learning for predicting lifespan-extending chemical compounds. Aging (Albany NY) (2017) 0.75
Predicting attention-deficit/hyperactivity disorder severity from psychosocial stress and stress-response genes: a random forest regression approach. Transl Psychiatry (2017) 0.75
Gene selection and classification of microarray data using random forest. BMC Bioinformatics (2006) 12.45
Detecting gene-gene interactions that underlie human diseases. Nat Rev Genet (2009) 12.07
Conditional variable importance for random forests. BMC Bioinformatics (2008) 6.07
Performance of random forest when SNPs are in linkage disequilibrium. BMC Bioinformatics (2009) 1.81
Predictor correlation impacts machine learning algorithms: implications for genomic studies. Bioinformatics (2009) 1.69
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Genomewide association analysis of coronary artery disease. N Engl J Med (2007) 24.38
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
Genetics and beyond--the transcriptome of human monocytes and disease susceptibility. PLoS One (2010) 7.48
Statistical analysis of rare sequence variants: an overview of collapsing methods. Genet Epidemiol (2011) 6.18
Gene map of the extended human MHC. Nat Rev Genet (2004) 6.01
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease. Circulation (2008) 5.20
New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet (2009) 5.12
Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risk locus for coronary artery disease. Nat Genet (2009) 4.63
New genes involved in cancer identified by retroviral tagging. Nat Genet (2002) 4.14
Global analysis of X-chromosome dosage compensation. J Biol (2006) 3.78
BRCA2 germline mutations in familial pancreatic carcinoma. J Natl Cancer Inst (2003) 3.37
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Predicting long-term outcome after acute ischemic stroke: a simple index works in patients from controlled clinical trials. Stroke (2008) 3.21
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
On safari to Random Jungle: a fast implementation of Random Forests for high-dimensional data. Bioinformatics (2010) 3.09
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature (2010) 2.88
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Candidate biomarkers for discrimination between infection and disease caused by Mycobacterium tuberculosis. J Mol Med (Berl) (2007) 2.69
Avoidance of mechanical ventilation by surfactant treatment of spontaneously breathing preterm infants (AMV): an open-label, randomised, controlled trial. Lancet (2011) 2.62
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. PLoS One (2008) 2.37
Grasping molecular structures through publication-integrated 3D models. Trends Biochem Sci (2008) 2.26
Brief review of regression-based and machine learning methods in genetic epidemiology: the Genetic Analysis Workshop 17 experience. Genet Epidemiol (2011) 2.25
SNP-based analysis of genetic substructure in the German population. Hum Hered (2006) 2.21
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Association between c135G/A genotype and RET proto-oncogene germline mutations and phenotype of Hirschsprung's disease. Lancet (2002) 2.10
Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA (2009) 2.10
Next-generation phenotyping using the parkin example: time to catch up with genetics. JAMA Neurol (2013) 2.02
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Strong genetic evidence of DCDC2 as a susceptibility gene for dyslexia. Am J Hum Genet (2005) 1.94
Predicting functional outcome and survival after acute ischemic stroke. J Neurol (2002) 1.92
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92
Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system. J Neurosurg (2006) 1.83
Triple target treatment (3T) is more effective than biofeedback alone for anal incontinence: the 3T-AI study. Dis Colon Rectum (2010) 1.81
Short-term prediction of mortality in patients with systemic lupus erythematosus: classification of outcomes using random forests. Arthritis Rheum (2006) 1.73
Predictor correlation impacts machine learning algorithms: implications for genomic studies. Bioinformatics (2009) 1.69
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units. Eur J Hum Genet (2010) 1.62
Opportunities and challenges for digital morphology. Biol Direct (2010) 1.60
Ankylosing spondylitis: a beta2m-deposition disease? Trends Immunol (2003) 1.55
Optimal classifier selection and negative bias in error rate estimation: an empirical study on high-dimensional prediction. BMC Med Res Methodol (2009) 1.53
Sepsis syndrome and death in trauma patients are associated with variation in the gene encoding tumor necrosis factor. Crit Care Med (2008) 1.53
Genome-wide association study indicates two novel resistance loci for severe malaria. Nature (2012) 1.52
A pooled analysis of melanocytic nevus phenotype and the risk of cutaneous melanoma at different latitudes. Int J Cancer (2009) 1.51
Individual radiosensitivity measured with lymphocytes may predict the risk of acute reaction after radiotherapy. Int J Radiat Oncol Biol Phys (2008) 1.50
Human genetic resistance to Onchocerca volvulus: evidence for linkage to chromosome 2p from an autosome-wide scan. J Infect Dis (2008) 1.49
Habit and skill learning in schizophrenia: evidence of normal striatal processing with abnormal cortical input. Learn Mem (2002) 1.48
A system-level pathway-phenotype association analysis using synthetic feature random forest. Genet Epidemiol (2014) 1.46
Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model. Virology (2002) 1.44
Anterior chamber angle measurement with optical coherence tomography: intraobserver and interobserver variability. J Cataract Refract Surg (2006) 1.43
HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum. J Biol Chem (2002) 1.41
Risk estimation using probability machines. BioData Min (2014) 1.40
Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet (2011) 1.40
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Medicine (Baltimore) (2006) 1.39
Colonic polyps: complementary role of computer-aided detection in CT colonography. Radiology (2002) 1.38
Oligoclonal expansion of memory CD8+ T cells in cerebrospinal fluid from multiple sclerosis patients. Brain (2002) 1.37
Picking single-nucleotide polymorphisms in forests. BMC Proc (2007) 1.36
The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol. J Mol Med (Berl) (2008) 1.35
Lessons learned from Genetic Analysis Workshop 17: transitioning from genome-wide association studies to whole-genome statistical genetic analysis. Genet Epidemiol (2011) 1.34
Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. Eur Urol (2009) 1.32
Dual, HLA-B27 subtype-dependent conformation of a self-peptide. J Exp Med (2004) 1.31
Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS One (2012) 1.31
Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet (2012) 1.29
Identification of genetic association of multiple rare variants using collapsing methods. Genet Epidemiol (2011) 1.26
Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet (2011) 1.26
Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. Eur Heart J (2010) 1.25
Effectively incorporating selected multimedia content into medical publications. BMC Med (2011) 1.24
Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians. Arthritis Rheum (2006) 1.24
Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis. Arthritis Rheum (2009) 1.21
Leaving the structural ivory tower, assisted by interactive 3D PDF. Trends Biochem Sci (2010) 1.19
The clinical phenotypes of the juvenile idiopathic inflammatory myopathies. Medicine (Baltimore) (2013) 1.19
Differential peptide dynamics is linked to major histocompatibility complex polymorphism. J Biol Chem (2004) 1.19
Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians. Medicine (Baltimore) (2005) 1.18
The songbird syrinx morphome: a three-dimensional, high-resolution, interactive morphological map of the zebra finch vocal organ. BMC Biol (2013) 1.18
CDKN2A germline mutations in familial pancreatic cancer. Ann Surg (2002) 1.18
p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb. Ann Surg (2002) 1.17
Genome-wide linkage analysis of malaria infection intensity and mild disease. PLoS Genet (2007) 1.13
HLA-B27 subtypes differentially associated with disease exhibit subtle structural alterations. J Biol Chem (2002) 1.13
A genotype-based approach to assessing the association between single nucleotide polymorphisms. Hum Hered (2008) 1.11
Computer-assisted detection of colonic polyps with CT colonography using neural networks and binary classification trees. Med Phys (2003) 1.10
Assessment of 3 xeroderma pigmentosum group C gene polymorphisms and risk of cutaneous melanoma: a case-control study. Carcinogenesis (2005) 1.09
HLA-B27 subtypes differentially associated with disease exhibit conformational differences in solution. J Mol Biol (2007) 1.08
Internal limiting membrane peeling with indocyanine green or trypan blue in macular hole surgery: a randomized trial. Arch Ophthalmol (2007) 1.08
Genome scan for childhood and adolescent obesity in German families. Pediatrics (2003) 1.08
Association of single nucleotide polymorphisms in ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with clinical and cellular radiosensitivity. Radiother Oncol (2010) 1.08
Expression profiling of laser-microdissected intrapulmonary arteries in hypoxia-induced pulmonary hypertension. Respir Res (2005) 1.07
Allele-dependent similarity between viral and self-peptide presentation by HLA-B27 subtypes. J Biol Chem (2004) 1.07
An AUC-based permutation variable importance measure for random forests. BMC Bioinformatics (2013) 1.07
Lack of association between the MEF2A gene and myocardial infarction. Circulation (2007) 1.07
Expression of free HLA class I heavy chains in an immune-privileged site: comment on the article by Taurog et al. Arthritis Rheum (2013) 1.07
Functional haplotypes of the RET proto-oncogene promoter are associated with Hirschsprung disease (HSCR). Hum Mol Genet (2003) 1.07
Ultrastructure and mineral distribution in the tergal cuticle of the terrestrial isopod Titanethes albus. Adaptations to a karst cave biotope. J Struct Biol (2009) 1.07