Published in Mol Syst Biol on May 23, 2014
Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis. J Lipid Res (2014) 1.27
Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population. Cell (2014) 1.13
Epigenome-wide association of liver methylation patterns and complex metabolic traits in mice. Cell Metab (2015) 0.97
Global diversity lines - a five-continent reference panel of sequenced Drosophila melanogaster strains. G3 (Bethesda) (2015) 0.94
Genetics of human metabolism: an update. Hum Mol Genet (2015) 0.87
Contrasting genetic architectures in different mouse reference populations used for studying complex traits. Genome Res (2015) 0.86
The Hybrid Mouse Diversity Panel: a resource for systems genetics analyses of metabolic and cardiovascular traits. J Lipid Res (2016) 0.83
Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series. Genome Med (2016) 0.80
The Genetic Landscape of Hematopoietic Stem Cell Frequency in Mice. Stem Cell Reports (2015) 0.79
From integrative genomics to systems genetics in the rat to link genotypes to phenotypes. Dis Model Mech (2016) 0.79
Genomewide landscape of gene-metabolome associations in Escherichia coli. Mol Syst Biol (2017) 0.78
Multi-omics approaches to disease. Genome Biol (2017) 0.76
Genetic control of obesity, glucose homeostasis, dyslipidemia and fatty liver in a mouse model of diet-induced metabolic syndrome. Int J Obes (Lond) (2015) 0.76
Reciprocal Regulation of the Cardiac Epigenome by Chromatin Structural Proteins Hmgb and Ctcf: IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION. J Biol Chem (2016) 0.75
New views on the selection acting on genetic polymorphism in central metabolic genes. Ann N Y Acad Sci (2016) 0.75
High-Resolution Metabolomics: Review of the Field and Implications for Nursing Science and the Study of Preterm Birth. Biol Res Nurs (2015) 0.75
Exploring multiple quantitative trait loci models of hepatic fibrosis in a mouse intercross. Mamm Genome (2015) 0.75
Statistical significance for genomewide studies. Proc Natl Acad Sci U S A (2003) 88.64
WGCNA: an R package for weighted correlation network analysis. BMC Bioinformatics (2008) 18.58
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression. Nature (2009) 12.58
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
Metabolite profiles and the risk of developing diabetes. Nat Med (2011) 12.22
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab (2009) 11.46
HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res (2008) 11.23
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
A sequence-based variation map of 8.27 million SNPs in inbred mouse strains. Nature (2007) 6.77
Human metabolic individuality in biomedical and pharmaceutical research. Nature (2011) 6.56
Human metabolic phenotype diversity and its association with diet and blood pressure. Nature (2008) 5.41
Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet (2008) 5.23
A genome-wide perspective of genetic variation in human metabolism. Nat Genet (2009) 5.00
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. Nature (1998) 3.84
A high-resolution association mapping panel for the dissection of complex traits in mice. Genome Res (2010) 3.81
Accurate discovery of expression quantitative trait loci under confounding from spurious and genuine regulatory hotspots. Genetics (2008) 3.66
Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet (2011) 3.23
Metabolomic identification of novel biomarkers of myocardial ischemia. Circulation (2005) 3.16
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. Cell Metab (2013) 3.01
Organization of GC/MS and LC/MS metabolomics data into chemical libraries. J Cheminform (2010) 2.69
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes (2009) 2.68
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS Genet (2008) 2.63
High heritability of metabolomic profiles in families burdened with premature cardiovascular disease. Mol Syst Biol (2009) 2.21
Metabonomic, transcriptomic, and genomic variation of a population cohort. Mol Syst Biol (2010) 2.17
Genetic control of obesity and gut microbiota composition in response to high-fat, high-sucrose diet in mice. Cell Metab (2013) 2.17
Untargeted metabolomic profiling as an evaluative tool of fenofibrate-induced toxicology in Fischer 344 male rats. Toxicol Pathol (2009) 2.16
Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. Anal Chem (2007) 2.15
Systems genetics approaches to understand complex traits. Nat Rev Genet (2013) 1.97
Mouse genome-wide association and systems genetics identify Asxl2 as a regulator of bone mineral density and osteoclastogenesis. PLoS Genet (2011) 1.68
Human metabolic profiles are stably controlled by genetic and environmental variation. Mol Syst Biol (2011) 1.60
Metabolic fingerprinting as a diagnostic tool. Pharmacogenomics (2007) 1.51
Influence of the apoA-II gene locus on HDL levels and fatty streak development in mice. Arterioscler Thromb (1993) 1.49
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. Mol Biosyst (2010) 1.44
Analytical approaches to metabolomics and applications to systems biology. Semin Nephrol (2010) 1.08
A sequence variation in the mitochondrial glycerol-3-phosphate dehydrogenase gene is associated with increased plasma glycerol and free fatty acid concentrations among French Canadians. Mol Genet Metab (2001) 0.84