Published in Nature on July 29, 2007
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev (2010) 7.14
High-throughput genotyping by whole-genome resequencing. Genome Res (2009) 5.74
Genomewide SNP variation reveals relationships among landraces and modern varieties of rice. Proc Natl Acad Sci U S A (2009) 4.65
Transcriptome-wide identification of novel imprinted genes in neonatal mouse brain. PLoS One (2008) 4.03
Comprehensive polymorphism survey elucidates population structure of Saccharomyces cerevisiae. Nature (2009) 3.67
Subspecific origin and haplotype diversity in the laboratory mouse. Nat Genet (2011) 3.64
A customized and versatile high-density genotyping array for the mouse. Nat Methods (2009) 3.53
Genetic analysis of complex traits in the emerging Collaborative Cross. Genome Res (2011) 3.25
Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet (2011) 3.23
Segmental copy number variation shapes tissue transcriptomes. Nat Genet (2009) 2.95
Global survey of escape from X inactivation by RNA-sequencing in mouse. Genome Res (2010) 2.87
The recombinational anatomy of a mouse chromosome. PLoS Genet (2008) 2.66
Parent-independent genotyping for constructing an ultrahigh-density linkage map based on population sequencing. Proc Natl Acad Sci U S A (2010) 2.63
Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective. PLoS Genet (2012) 2.57
An imputed genotype resource for the laboratory mouse. Mamm Genome (2008) 2.54
The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA. Genes Dev (2011) 2.53
Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes. Genome Res (2010) 2.37
A genome wide survey of SNP variation reveals the genetic structure of sheep breeds. PLoS One (2009) 2.22
Effect of natural genetic variation on enhancer selection and function. Nature (2013) 2.10
Genome-wide patterns of genetic variation in sweet and grain sorghum (Sorghum bicolor). Genome Biol (2011) 2.02
High-resolution analysis of epigenetic changes associated with X inactivation. Genome Res (2009) 2.02
Strain screen and haplotype association mapping of wheel running in inbred mouse strains. J Appl Physiol (1985) (2010) 1.88
Fine-scale phylogenetic discordance across the house mouse genome. PLoS Genet (2009) 1.83
High resolution mapping of expression QTLs in heterogeneous stock mice in multiple tissues. Genome Res (2009) 1.83
Detecting polymorphic regions in Arabidopsis thaliana with resequencing microarrays. Genome Res (2008) 1.82
Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences. Genome Res (2009) 1.80
Genome-wide association studies in mice. Nat Rev Genet (2012) 1.75
Asymmetry and polymorphism of hybrid male sterility during the early stages of speciation in house mice. Evolution (2007) 1.74
Fine mapping in 94 inbred mouse strains using a high-density haplotype resource. Genetics (2010) 1.71
Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements. PLoS Genet (2008) 1.69
Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition. Genome Res (2008) 1.69
A second generation genetic map for rainbow trout (Oncorhynchus mykiss). BMC Genet (2008) 1.68
Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest (2009) 1.67
Mouse consomic strains: exploiting genetic divergence between Mus m. musculus and Mus m. domesticus subspecies. Genome Res (2008) 1.66
Mouse phenome database. Nucleic Acids Res (2008) 1.59
Commercially available outbred mice for genome-wide association studies. PLoS Genet (2010) 1.58
A complex genetic basis to X-linked hybrid male sterility between two species of house mice. Genetics (2008) 1.58
Nucleotide variation in wild and inbred mice. Genetics (2007) 1.55
Collaborative Cross mice and their power to map host susceptibility to Aspergillus fumigatus infection. Genome Res (2011) 1.55
Dynamics of gene silencing during X inactivation using allele-specific RNA-seq. Genome Biol (2015) 1.53
Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest (2009) 1.49
wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data. Nucleic Acids Res (2008) 1.48
Sequencing and characterization of the FVB/NJ mouse genome. Genome Biol (2012) 1.48
Discovery of ZIP transporters that participate in cadmium damage to testis and kidney. Toxicol Appl Pharmacol (2009) 1.46
Mouse inter-subspecific consomic strains for genetic dissection of quantitative complex traits. Genome Res (2008) 1.46
The genome sequence of the spontaneously hypertensive rat: Analysis and functional significance. Genome Res (2010) 1.45
Gene expression in the mouse eye: an online resource for genetics using 103 strains of mice. Mol Vis (2009) 1.44
Progress in genetic studies of pain and analgesia. Annu Rev Pharmacol Toxicol (2009) 1.43
Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels. Genome Biol (2009) 1.43
Hybrid mouse diversity panel: a panel of inbred mouse strains suitable for analysis of complex genetic traits. Mamm Genome (2012) 1.43
Next-generation sequencing of vertebrate experimental organisms. Mamm Genome (2009) 1.42
Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny. Genetics (2012) 1.42
Allelic imbalance sequencing reveals that single-nucleotide polymorphisms frequently alter microRNA-directed repression. Nat Biotechnol (2009) 1.39
Discovery of novel variants in genotyping arrays improves genotype retention and reduces ascertainment bias. BMC Genomics (2012) 1.39
Establishment of "The Gene Mine": a resource for rapid identification of complex trait genes. Mamm Genome (2008) 1.38
Estimating enrichment of repetitive elements from high-throughput sequence data. Genome Biol (2010) 1.38
An integrative genetics approach to identify candidate genes regulating BMD: combining linkage, gene expression, and association. J Bone Miner Res (2009) 1.33
Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies. PLoS One (2009) 1.27
Inheritance patterns of progressive hearing loss in laboratory strains of mice. Brain Res (2009) 1.26
FastMap: fast eQTL mapping in homozygous populations. Bioinformatics (2008) 1.25
Genetic dissection of a key reproductive barrier between nascent species of house mice. Genetics (2011) 1.25
Identification of novel genes that mediate innate immunity using inbred mice. Genetics (2009) 1.22
H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load. MBio (2011) 1.22
A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. Circ Cardiovasc Genet (2009) 1.19
Higher differentiation among subspecies of the house mouse (Mus musculus) in genomic regions with low recombination. Mol Ecol (2011) 1.17
Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog (2010) 1.17
Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res (2009) 1.16
Sequencing by Cyclic Ligation and Cleavage (CycLiC) directly on a microarray captured template. Nucleic Acids Res (2008) 1.16
Intra- and inter-individual genetic differences in gene expression. Mamm Genome (2009) 1.16
Cancer evolution and individual susceptibility. Integr Biol (Camb) (2011) 1.15
Mouse Phenome Database (MPD). Nucleic Acids Res (2011) 1.14
The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains. Genome Res (2013) 1.14
Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction. Nat Neurosci (2011) 1.13
Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice. BMC Genet (2012) 1.11
The long path from QTL to gene. PLoS Genet (2012) 1.11
Genetic modulation of striatal volume by loci on Chrs 6 and 17 in BXD recombinant inbred mice. Genes Brain Behav (2009) 1.10
Comt1 genotype and expression predicts anxiety and nociceptive sensitivity in inbred strains of mice. Genes Brain Behav (2010) 1.09
Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps. Genome Res (2010) 1.09
Deconstructing Mus gemischus: advances in understanding ancestry, structure, and variation in the genome of the laboratory mouse. Mamm Genome (2012) 1.08
Proteomics and comparative genomic investigations reveal heterogeneity in evolutionary rate of male reproductive proteins in mice (Mus domesticus). Mol Biol Evol (2009) 1.07
The genetic control of neocortex volume and covariation with neocortical gene expression in mice. BMC Neurosci (2009) 1.07
Polymorphism in hybrid male sterility in wild-derived Mus musculus musculus strains on proximal chromosome 17. Mamm Genome (2009) 1.07
Genetic validation of whole-transcriptome sequencing for mapping expression affected by cis-regulatory variation. BMC Genomics (2010) 1.06
Natural variation in decision-making behavior in Drosophila melanogaster. PLoS One (2011) 1.06
Mouse gestation length is genetically determined. PLoS One (2010) 1.06
Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One (2011) 1.06
Evolutionary and dispersal history of Eurasian house mice Mus musculus clarified by more extensive geographic sampling of mitochondrial DNA. Heredity (Edinb) (2013) 1.06
The mouse genetics toolkit: revealing function and mechanism. Genome Biol (2011) 1.05
Modifier genes and the plasticity of genetic networks in mice. PLoS Genet (2012) 1.05
Systematic detection of polygenic cis-regulatory evolution. PLoS Genet (2011) 1.05
Searching for genes underlying behavior: lessons from circadian rhythms. Science (2008) 1.04
Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse. Nat Genet (2015) 1.04
Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus. Kidney Int (2008) 1.04
Assessing the prospects of genome-wide association studies performed in inbred mice. Mamm Genome (2010) 1.04
Variation in genomic recombination rates among heterogeneous stock mice. Genetics (2009) 1.04
Rice molecular breeding laboratories in the genomics era: Current status and future considerations. Int J Plant Genomics (2008) 1.04
Rapid evolution of mouse Y centromere repeat DNA belies recent sequence stability. Genome Res (2009) 1.04
Paternally biased X inactivation in mouse neonatal brain. Genome Biol (2010) 1.03
PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92
Initial sequencing and comparative analysis of the mouse genome. Nature (2002) 96.15
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
An integrated map of genetic variation from 1,092 human genomes. Nature (2012) 59.82
A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat Genet (2011) 59.36
PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet (2003) 53.59
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science (2007) 51.70
The structure of haplotype blocks in the human genome. Science (2002) 50.88
The genomic landscapes of human breast and colorectal cancers. Science (2007) 38.12
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Genome-wide association studies for common diseases and complex traits. Nat Rev Genet (2005) 33.96
Integrating common and rare genetic variation in diverse human populations. Nature (2010) 32.30
The landscape of somatic copy-number alteration across human cancers. Nature (2010) 31.88
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science (2006) 27.49
Efficiency and power in genetic association studies. Nat Genet (2005) 25.56
Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature (2005) 23.04
Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays. Science (2009) 21.24
Whole-genome patterns of common DNA variation in three human populations. Science (2005) 21.22
A common allele on chromosome 9 associated with coronary heart disease. Science (2007) 20.37
Association between microdeletion and microduplication at 16p11.2 and autism. N Engl J Med (2008) 19.71
Integrated detection and population-genetic analysis of SNPs and copy number variation. Nat Genet (2008) 19.55
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet (2007) 19.08
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet (2010) 17.38
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (2012) 17.12
Risk alleles for multiple sclerosis identified by a genomewide study. N Engl J Med (2007) 17.06
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet (2008) 15.89
Common deletion polymorphisms in the human genome. Nat Genet (2006) 15.66
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet (2006) 15.63
Variance component model to account for sample structure in genome-wide association studies. Nat Genet (2010) 15.52
Genetic mapping in human disease. Science (2008) 15.12
Calibrating a coalescent simulation of human genome sequence variation. Genome Res (2005) 15.04
Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet (2006) 14.76
Assessing computational tools for the discovery of transcription factor binding sites. Nat Biotechnol (2005) 14.29
Patterns and rates of exonic de novo mutations in autism spectrum disorders. Nature (2012) 13.71
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23
A global reference for human genetic variation. Nature (2015) 12.85
A comparison of phasing algorithms for trios and unrelated individuals. Am J Hum Genet (2006) 12.45
Efficient control of population structure in model organism association mapping. Genetics (2008) 12.32
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat Genet (2009) 12.19
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet (2008) 12.07
Methods for high-density admixture mapping of disease genes. Am J Hum Genet (2004) 12.02
Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol (2008) 11.28
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Mouse genomic variation and its effect on phenotypes and gene regulation. Nature (2011) 10.66
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana. Science (2007) 9.85
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet (2008) 9.52
Testing for an unusual distribution of rare variants. PLoS Genet (2011) 9.28
Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants. Nature (2012) 8.91
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions. PLoS Genet (2009) 8.39
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet (2011) 7.98
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences. Nature (2007) 7.91
Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration. Nat Genet (2006) 7.49
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet (2009) 7.16
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
High-resolution whole-genome association study of Parkinson disease. Am J Hum Genet (2005) 6.86
Exome sequencing, ANGPTL3 mutations, and familial combined hypolipidemia. N Engl J Med (2010) 6.84
The mosaic structure of variation in the laboratory mouse genome. Nature (2002) 6.54
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. Nat Genet (2008) 6.42
Parental phenotypes in family-based association analysis. Am J Hum Genet (2004) 6.35
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet (2011) 6.20
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet (2012) 6.15
Ascertainment through family history of disease often decreases the power of family-based association studies. Behav Genet (2007) 6.06
Genome-wide scan identifies variation in MLXIPL associated with plasma triglycerides. Nat Genet (2008) 6.06
Haplotype reconstruction from genotype data using Imperfect Phylogeny. Bioinformatics (2004) 6.02
Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet (2007) 5.99
Genetic architectures of psychiatric disorders: the emerging picture and its implications. Nat Rev Genet (2012) 5.99
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet (2010) 5.79
Genome-wide mapping of DNase hypersensitive sites using massively parallel signature sequencing (MPSS). Genome Res (2005) 5.71
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nat Genet (2011) 5.58
Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis. Nature (2006) 5.52
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Low-coverage sequencing: implications for design of complex trait association studies. Genome Res (2011) 5.34
Synaptic, transcriptional and chromatin genes disrupted in autism. Nature (2014) 5.30
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet (2008) 5.08