Published in J Zhejiang Univ Sci B on December 01, 2014
Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11. BMC Evol Biol (2015) 0.82
Ubiquitin-specific protease 11 (USP11) functions as a tumor suppressor through deubiquitinating and stabilizing VGLL4 protein. Am J Cancer Res (2016) 0.75
DUBbing Cancer: Deubiquitylating Enzymes Involved in Epigenetics, DNA Damage and the Cell Cycle As Therapeutic Targets. Front Genet (2016) 0.75
Surfing the p53 network. Nature (2000) 35.36
Mdm2 promotes the rapid degradation of p53. Nature (1997) 21.26
Regulation of p53 stability by Mdm2. Nature (1997) 18.20
Blinded by the Light: The Growing Complexity of p53. Cell (2009) 17.75
TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell (2006) 11.85
Defining the human deubiquitinating enzyme interaction landscape. Cell (2009) 11.39
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett (1997) 11.19
Transcriptional control of human p53-regulated genes. Nat Rev Mol Cell Biol (2008) 11.05
The p53 pathway: positive and negative feedback loops. Oncogene (2005) 9.75
Modes of p53 regulation. Cell (2009) 9.31
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature (2002) 7.71
p53 ubiquitination: Mdm2 and beyond. Mol Cell (2006) 5.57
The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature (2004) 5.05
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell (2003) 4.96
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell (2005) 4.60
The p53-Mdm2 module and the ubiquitin system. Semin Cancer Biol (2003) 4.46
A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell (2004) 4.05
USP10 regulates p53 localization and stability by deubiquitinating p53. Cell (2010) 3.17
Tumour suppression: disruption of HAUSP gene stabilizes p53. Nature (2004) 2.83
The MDM2-p53 pathway revisited. J Biomed Res (2013) 1.52
BRCA2 is ubiquitinated in vivo and interacts with USP11, a deubiquitinating enzyme that exhibits prosurvival function in the cellular response to DNA damage. Mol Cell Biol (2004) 1.44
Positive regulation of p53 stability and activity by the deubiquitinating enzyme Otubain 1. EMBO J (2011) 1.38
ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation. Cell Cycle (2005) 1.29
JTV1 co-activates FBP to induce USP29 transcription and stabilize p53 in response to oxidative stress. EMBO J (2011) 1.28
Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair. J Biol Chem (2010) 1.26
Regulatory role of p53 in cancer metabolism via SCO2 and TIGAR in human breast cancer. Hum Pathol (2011) 1.13
Structural and functional characterization of the USP11 deubiquitinating enzyme, which interacts with the RanGTP-associated protein RanBPM. Biochem J (2002) 1.11
The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha). J Biol Chem (2007) 1.09
USP11 negatively regulates TNFalpha-induced NF-kappaB activation by targeting on IkappaBalpha. Cell Signal (2010) 1.09
USP11 augments TGFβ signalling by deubiquitylating ALK5. Open Biol (2012) 1.07
TIGAR induces p53-mediated cell-cycle arrest by regulation of RB-E2F1 complex. Br J Cancer (2012) 0.93
Tumor suppressor p53 and its gain-of-function mutants in cancer. Acta Biochim Biophys Sin (Shanghai) (2013) 0.89
Monoubiquitination is critical for ovarian tumor domain-containing ubiquitin aldehyde binding protein 1 (Otub1) to suppress UbcH5 enzyme and stabilize p53 protein. J Biol Chem (2014) 0.89
USP11 regulates PML stability to control Notch-induced malignancy in brain tumours. Nat Commun (2014) 0.88
Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1. World J Biol Chem (2014) 0.84
Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer. Oncol Rep (2012) 0.81
OTUD5 regulates p53 stability by deubiquitinating p53. PLoS One (2013) 0.80
E3 ubiquitin ligase Cullin4B mediated polyubiquitination of p53 for its degradation. Mol Cell Biochem (2014) 0.80
[A clinical study of severe hepatitis treated with a partial plasma exchange artificial liver support system]. Zhonghua Gan Zang Bing Za Zhi (2006) 0.80
A simple noninvasive index to predict significant liver fibrosis in patients with advanced schistosomiasis japonica. Parasitol Int (2013) 0.75
[Factors influencing the development of portal hypertensive gastropathy with liver fibrosis in schistosomiasis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2003) 0.75
[Application of internal fixation combined with external fixator for unstable pelvic fracture]. Zhongguo Gu Shang (2015) 0.75
[The clinical significance of interferon-gamma and its receptor in patients with schistosomiasis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi (2004) 0.75