Published in Aging (Albany NY) on December 01, 2014
Long noncoding RNAs in diseases of aging. Biochim Biophys Acta (2015) 0.88
The Role of Extracellular Vesicles: An Epigenetic View of the Cancer Microenvironment. Biomed Res Int (2015) 0.86
The Aging Epigenome. Mol Cell (2016) 0.84
LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR. Nucleic Acids Res (2016) 0.80
Coronary artery calcifications predict long term cardiovascular events in non diabetic Caucasian hemodialysis patients. Aging (Albany NY) (2015) 0.78
Genetic variants and cellular stressors associated with exfoliation syndrome modulate promoter activity of a lncRNA within the LOXL1 locus. Hum Mol Genet (2015) 0.76
LncRNA mediated regulation of aging pathways in Drosophila melanogaster during dietary restriction. Aging (Albany NY) (2016) 0.76
Nucleotide diversity inflation as a genome-wide response to experimental lifespan extension in Drosophila melanogaster. BMC Genomics (2017) 0.75
Extracellular RNA in aging. Wiley Interdiscip Rev RNA (2016) 0.75
Expression Profiling of mRNAs and Long Non-Coding RNAs in Aged Mouse Olfactory Bulb. Sci Rep (2017) 0.75
Insights into long noncoding RNAs of naked mole rat (Heterocephalus glaber) and their potential association with cancer resistance. Epigenetics Chromatin (2016) 0.75
Long Non-Coding RNAs: A Novel Paradigm for Toxicology. Toxicol Sci (2016) 0.75
Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosis. J Clin Invest (2017) 0.75
Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq. PLoS One (2016) 0.75
Shining the Light on Senescence Associated LncRNAs. Aging Dis (2017) 0.75
Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice. Biomed Res Int (2016) 0.75
The role of epigenetics in renal ageing. Nat Rev Nephrol (2017) 0.75
Molecular and phenotypic biomarkers of aging. F1000Res (2017) 0.75
Epigenetics and Oxidative Stress in Aging. Oxid Med Cell Longev (2017) 0.75
P16 (INK4a) Deletion Ameliorated Renal Tubulointerstitial Injury in a Stress-induced Premature Senescence Model of Bmi-1 Deficiency. Sci Rep (2017) 0.75
Long Noncoding RNAs and RNA-Binding Proteins in Oxidative Stress, Cellular Senescence, and Age-Related Diseases. Oxid Med Cell Longev (2017) 0.75
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10
Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
The hallmarks of aging. Cell (2013) 14.29
Adapting proteostasis for disease intervention. Science (2008) 13.22
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature (1989) 13.18
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol (2008) 11.43
lincRNAs act in the circuitry controlling pluripotency and differentiation. Nature (2011) 11.31
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulation. Mol Cell (2008) 9.76
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev (2004) 8.66
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell (2005) 8.65
The essence of senescence. Genes Dev (2010) 8.21
Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription. Nature (2008) 7.18
Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol Cell (2010) 6.94
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation. Genome Res (2008) 6.43
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends. Science (2007) 6.33
Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2. Genes Dev (1998) 6.29
Autophagy and aging. Cell (2011) 5.96
lncRNAs transactivate STAU1-mediated mRNA decay by duplexing with 3' UTRs via Alu elements. Nature (2011) 5.42
Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells. Nat Genet (2010) 5.37
Biological and chemical approaches to diseases of proteostasis deficiency. Annu Rev Biochem (2009) 5.23
Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA. Dev Cell (2005) 4.83
Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene. Oncogene (2010) 4.81
Epigenetic regulation by long noncoding RNAs. Science (2012) 4.74
A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell (2006) 4.74
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA. Gastroenterology (2006) 4.70
The multilayered complexity of ceRNA crosstalk and competition. Nature (2014) 4.15
Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. Cancer Cell (2006) 4.10
LincRNA-p21 suppresses target mRNA translation. Mol Cell (2012) 3.87
Inflammatory networks during cellular senescence: causes and consequences. Trends Mol Med (2010) 3.79
GAS5, a non-protein-coding RNA, controls apoptosis and is downregulated in breast cancer. Oncogene (2008) 3.79
The H19 non-coding RNA is essential for human tumor growth. PLoS One (2007) 3.75
eRNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell (2012) 3.63
Epigenetics and aging: the targets and the marks. Trends Genet (2007) 3.44
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus. Cell (2013) 3.40
Long noncoding RNAs: past, present, and future. Genetics (2013) 3.16
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. Nature (2012) 3.08
Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology (2011) 3.05
The role of senescent cells in ageing. Nature (2014) 3.03
Widespread and tissue specific age-related DNA methylation changes in mice. Genome Res (2010) 2.99
C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4. Mol Cell (2001) 2.97
Interaction of noncoding RNA with the rDNA promoter mediates recruitment of DNMT3b and silencing of rRNA genes. Genes Dev (2010) 2.96
Tissue-specific transcriptional enhancers may act in trans on the gene located in the homologous chromosome: the molecular basis of transvection in Drosophila. EMBO J (1990) 2.91
Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell (2013) 2.77
A pituitary-derived MEG3 isoform functions as a growth suppressor in tumor cells. J Clin Endocrinol Metab (2003) 2.68
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature (2010) 2.67
TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres. Mol Cell (2009) 2.60
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. EMBO Rep (2001) 2.59
Long noncoding RNA MALAT1 controls cell cycle progression by regulating the expression of oncogenic transcription factor B-MYB. PLoS Genet (2013) 2.59
A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis. Nature (1994) 2.51
Human long non-coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors. EMBO J (2011) 2.51
The c-Myc oncogene directly induces the H19 noncoding RNA by allele-specific binding to potentiate tumorigenesis. Cancer Res (2006) 2.50
MEG3 noncoding RNA: a tumor suppressor. J Mol Endocrinol (2012) 2.41
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells. Nat Struct Mol Biol (2013) 2.33
The H19 locus: role of an imprinted non-coding RNA in growth and development. Bioessays (2010) 2.23
Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing. Science (2012) 2.22
Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway. Cell Metab (2011) 2.22
The role of nuclear architecture in genomic instability and ageing. Nat Rev Mol Cell Biol (2007) 2.17
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature (2011) 2.17
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. J Biol Chem (2012) 2.16
DNA damage, cellular senescence and organismal ageing: causal or correlative? Nucleic Acids Res (2007) 2.09
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res (2010) 2.05
DNMT1-interacting RNAs block gene-specific DNA methylation. Nature (2013) 2.04
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis. Proc Natl Acad Sci U S A (1996) 1.99
Rapid identification of UCA1 as a very sensitive and specific unique marker for human bladder carcinoma. Clin Cancer Res (2006) 1.97
Inhibition of metastasis-associated lung adenocarcinoma transcript 1 in CaSki human cervical cancer cells suppresses cell proliferation and invasion. Acta Biochim Biophys Sin (Shanghai) (2010) 1.95
Senescence and aging: the critical roles of p53. Oncogene (2013) 1.90
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol (2012) 1.90
A dual role of p53 in the control of autophagy. Autophagy (2008) 1.88
Expression and functional role of a transcribed noncoding RNA with an ultraconserved element in hepatocellular carcinoma. Proc Natl Acad Sci U S A (2010) 1.87
Downregulation of Wnt signaling is a trigger for formation of facultative heterochromatin and onset of cell senescence in primary human cells. Mol Cell (2007) 1.87
Posttranscriptional gene regulation by long noncoding RNA. J Mol Biol (2012) 1.87
Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis. Eur J Gastroenterol Hepatol (2009) 1.85
Long non-coding RNA UCA1 promotes breast tumor growth by suppression of p27 (Kip1). Cell Death Dis (2014) 1.80
Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells. RNA (2009) 1.78
Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol (2003) 1.78
The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL. Proc Natl Acad Sci U S A (2013) 1.78
RNA templating the epigenome: long noncoding RNAs as molecular scaffolds. Epigenetics (2011) 1.75
Expression of neural BC200 RNA in human tumours. J Pathol (1997) 1.70
The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage. Cell Res (2012) 1.66
RNAs as extracellular signaling molecules. J Mol Endocrinol (2008) 1.64
A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. Elife (2013) 1.63
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination. Nat Commun (2013) 1.62
Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) (2012) 1.58
Role of long non-coding RNA HULC in cell proliferation, apoptosis and tumor metastasis of gastric cancer: a clinical and in vitro investigation. Oncol Rep (2013) 1.56
Physiological assembly and activity of human telomerase complexes. Mech Ageing Dev (2007) 1.56
UCHL1 is a Parkinson's disease susceptibility gene. Ann Neurol (2004) 1.54
Transcriptional enhancers in development and disease. Genome Biol (2012) 1.52
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma. Clin Cancer Res (2013) 1.51
Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2. Genome Biol (2013) 1.47
Extracellular Vesicle-Mediated Transfer of a Novel Long Noncoding RNA TUC339: A Mechanism of Intercellular Signaling in Human Hepatocellular Cancer. Genes Cancer (2013) 1.47
Polycomb Repressive Complex 2 and Trithorax modulate Drosophila longevity and stress resistance. Proc Natl Acad Sci U S A (2009) 1.45
Long noncoding RNAs in cell and developmental biology. Semin Cell Dev Biol (2011) 1.43
Long non-coding RNAs: modulators of nuclear structure and function. Curr Opin Cell Biol (2013) 1.43
Altered expression of C/EBP family members results in decreased adipogenesis with aging. Am J Physiol Regul Integr Comp Physiol (2001) 1.40
Transcriptional networks and cellular senescence in human mammary fibroblasts. Mol Biol Cell (2004) 1.38
Downregulated MEG3 activates autophagy and increases cell proliferation in bladder cancer. Mol Biosyst (2013) 1.37
A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo. Blood (2009) 1.37
HuD regulates coding and noncoding RNA to induce APP→Aβ processing. Cell Rep (2014) 0.92
LncRNA OIP5-AS1/cyrano sponges RNA-binding protein HuR. Nucleic Acids Res (2016) 0.80
Alternative Splicing of Neuronal Differentiation Factor TRF2 Regulated by HNRNPH1/H2. Cell Rep (2016) 0.76
RNA-binding protein HuD reduces triglyceride production in pancreatic β cells by enhancing the expression of insulin-induced gene 1. Biochim Biophys Acta (2016) 0.76
WIG1 is crucial for AGO2-mediated ACOT7 mRNA silencing via miRNA-dependent and -independent mechanisms. Nucleic Acids Res (2017) 0.75