Published in Intensive Care Med on January 30, 2015
Hyperoxia: is it a biomarker for mortality? Intensive Care Med (2015) 1.06
Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update. Ann Intensive Care (2015) 0.88
Bench-to-bedside review: the effects of hyperoxia during critical illness. Crit Care (2015) 0.86
Non-invasive monitoring of oxygen delivery in acutely ill patients: new frontiers. Ann Intensive Care (2015) 0.75
Understanding the benefits and harms of oxygen therapy: response to comments by Akca. Intensive Care Med (2015) 0.75
Hydrocortisone therapy for patients with septic shock. N Engl J Med (2008) 15.85
Trial of early, goal-directed resuscitation for septic shock. N Engl J Med (2015) 8.24
High versus low blood-pressure target in patients with septic shock. N Engl J Med (2014) 7.37
Effect of heart rate control with esmolol on hemodynamic and clinical outcomes in patients with septic shock: a randomized clinical trial. JAMA (2013) 7.23
Assessment of the clinical effectiveness of pulmonary artery catheters in management of patients in intensive care (PAC-Man): a randomised controlled trial. Lancet (2005) 6.33
Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine. Crit Care Med (2008) 5.30
Isolation of patients in single rooms or cohorts to reduce spread of MRSA in intensive-care units: prospective two-centre study. Lancet (2005) 5.01
Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet (2002) 4.42
Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Heart Failure of the European Society of Cardiology. Eur Heart J (2005) 3.50
The effects of etomidate on adrenal responsiveness and mortality in patients with septic shock. Intensive Care Med (2009) 3.30
Cre-mediated cell ablation contests mast cell contribution in models of antibody- and T cell-mediated autoimmunity. Immunity (2011) 2.87
Mechanisms of sepsis-induced cardiac dysfunction. Crit Care Med (2007) 2.79
Abandon the mouse research ship? Not just yet! Shock (2014) 2.60
Statin use and mortality in the bacteremic critically ill patient. Crit Care Med (2006) 2.57
Erythropoietin during porcine aortic balloon occlusion-induced ischemia/reperfusion injury. Crit Care Med (2008) 2.50
Survival in critical illness is associated with early activation of mitochondrial biogenesis. Am J Respir Crit Care Med (2010) 2.48
The Pancreatitis Outcome Prediction (POP) Score: a new prognostic index for patients with severe acute pancreatitis. Crit Care Med (2007) 2.45
Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections. Crit Care Med (2015) 2.37
Prevalence and outcome of cirrhosis patients admitted to UK intensive care: a comparison against dialysis-dependent chronic renal failure patients. Intensive Care Med (2012) 2.33
Mechanisms of sepsis-induced organ dysfunction. Crit Care Med (2007) 2.30
The impact of enhanced cleaning within the intensive care unit on contamination of the near-patient environment with hospital pathogens: a randomized crossover study in critical care units in two hospitals. Crit Care Med (2011) 2.23
Systemic, pulmonary, and hepatosplanchnic effects of N-acetylcysteine during long-term porcine endotoxemia. Crit Care Med (2004) 2.14
Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit. Crit Care (2005) 2.03
Terlipressin for norepinephrine-resistant septic shock. Lancet (2002) 1.99
Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting? Crit Care Med (2009) 1.99
Mitochondrial dysfunction in a long-term rodent model of sepsis and organ failure. Am J Physiol Regul Integr Comp Physiol (2003) 1.95
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix. Cell Metab (2011) 1.87
Effects of ventilation with 100% oxygen during early hyperdynamic porcine fecal peritonitis. Crit Care Med (2008) 1.85
Effects of levosimendan on systemic and regional hemodynamics in septic myocardial depression. Intensive Care Med (2005) 1.83
Microvascular effects of heart rate control with esmolol in patients with septic shock: a pilot study. Crit Care Med (2013) 1.81
Variability in management of early severe sepsis. Emerg Med J (2010) 1.76
Tracking changes in cardiac output: methodological considerations for the validation of monitoring devices. Intensive Care Med (2009) 1.76
Adrenal function in sepsis: the retrospective Corticus cohort study. Crit Care Med (2007) 1.74
Hypoxia accelerates nitric oxide-dependent inhibition of mitochondrial complex I in activated macrophages. Am J Physiol Regul Integr Comp Physiol (2004) 1.74
H1N1 pneumonitis treated with intravenous zanamivir. Lancet (2009) 1.73
Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice. Crit Care Med (2010) 1.70
Potential metabolic consequences of statins in sepsis. Crit Care Med (2011) 1.64
Clinical review: Update on hemodynamic monitoring--a consensus of 16. Crit Care (2011) 1.62
Comparison of carbamylated erythropoietin-FC fusion protein and recombinant human erythropoietin during porcine aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury. Intensive Care Med (2011) 1.60
Effects of intravenous sulfide during resuscitated porcine hemorrhagic shock*. Crit Care Med (2012) 1.58
Oxygen consumption of human peripheral blood mononuclear cells in severe human sepsis. Crit Care Med (2007) 1.58
Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock. Crit Care Med (2006) 1.54
Temporal changes in tissue cardiorespiratory function during faecal peritonitis. Intensive Care Med (2011) 1.54
Microvascular and interstitial oxygen tension in the renal cortex and medulla studied in a 4-h rat model of LPS-induced endotoxemia. Shock (2011) 1.52
Differential effects of vasopressin and norepinephrine on vascular reactivity in a long-term rodent model of sepsis. Crit Care Med (2007) 1.50
Ethyl pyruvate improves systemic and hepatosplanchnic hemodynamics and prevents lipid peroxidation in a porcine model of resuscitated hyperdynamic endotoxemia. Crit Care Med (2005) 1.49
The impact of inspired oxygen concentration on tissue oxygenation during progressive haemorrhage. Intensive Care Med (2009) 1.48
Effects of tempol, a free radical scavenger, on long-term hyperdynamic porcine bacteremia. Crit Care Med (2005) 1.48
Post hoc insights from PAC-Man--the U.K. pulmonary artery catheter trial. Crit Care Med (2008) 1.48
Low-molecular-weight polyethylene glycol improves survival in experimental sepsis. Crit Care Med (2010) 1.45
Critical care: advances and future perspectives. Lancet (2010) 1.44
Intensive care and emergency medicine: progress over the past 25 years. Chest (2006) 1.43
Metaphyseal fracture healing in a sheep model of low turnover osteoporosis induced by hypothalamic-pituitary disconnection (HPD). J Orthop Res (2013) 1.42
The FTc is not an accurate marker of left ventricular preload. Intensive Care Med (2006) 1.42
Infrared ear thermometry in water-related accidents-not a good choice. J Emerg Med (2008) 1.41
Adenosine triphosphate-magnesium dichloride during hyperdynamic porcine endotoxemia: effects on hepatosplanchnic oxygen exchange and metabolism. Crit Care Med (2002) 1.40
Multicenter, randomized, placebo-controlled phase III study of pyridoxalated hemoglobin polyoxyethylene in distributive shock (PHOENIX). Crit Care Med (2015) 1.40
Effects of Hyperoxia and Mild Therapeutic Hypothermia During Resuscitation From Porcine Hemorrhagic Shock. Crit Care Med (2016) 1.40
In vivo killing of Staphylococcus aureus using a light-activated antimicrobial agent. BMC Microbiol (2009) 1.40
Inhibition of vascular adenosine triphosphate-sensitive potassium channels by sympathetic tone during sepsis. Crit Care Med (2012) 1.38
The validity of trans-esophageal Doppler ultrasonography as a measure of cardiac output in critically ill adults. Intensive Care Med (2004) 1.37
Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability. Circulation (2005) 1.33
Bench-to-bedside review: Hydrogen sulfide--the third gaseous transmitter: applications for critical care. Crit Care (2009) 1.31
Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure. Crit Care (2006) 1.30
Mitochondrial Dysfunction in Sepsis. Curr Infect Dis Rep (2003) 1.30
Cardioprotection, attenuated systemic inflammation, and survival benefit of beta1-adrenoceptor blockade in severe sepsis in rats. Crit Care Med (2010) 1.30
Cellular energetic metabolism in sepsis: the need for a systems approach. Biochim Biophys Acta (2008) 1.28
Vasopressin: mechanisms of action on the vasculature in health and in septic shock. Crit Care Med (2007) 1.28
Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis. PLoS Med (2012) 1.27
TREM-1 promotes survival during septic shock in mice. Eur J Immunol (2007) 1.27
Hemodynamic and metabolic effects of hydrogen sulfide during porcine ischemia/reperfusion injury. Shock (2008) 1.26
Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication. Crit Care (2010) 1.22
Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs. Crit Care (2008) 1.20
Glucose metabolism and catecholamines. Crit Care Med (2007) 1.19
Physiological and clinical aspects of apnea diving. Clin Chest Med (2005) 1.19
British HIV Association and British Infection Association guidelines for the treatment of opportunistic infection in HIV-seropositive individuals 2011. HIV Med (2011) 1.17
The heart in sepsis: from basic mechanisms to clinical management. Curr Vasc Pharmacol (2013) 1.16
Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Crit Care Med (2017) 1.15
Target blood pressure in sepsis: between a rock and a hard place. Crit Care (2013) 1.13
Endotoxin elimination in sepsis: physiology and therapeutic application. Langenbecks Arch Surg (2010) 1.12
Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects. Br J Pharmacol (2014) 1.10
Effects of hydrogen sulfide on hemodynamics, inflammatory response and oxidative stress during resuscitated hemorrhagic shock in rats. Crit Care (2010) 1.08
Nitric oxide synthase inhibition in sepsis? Lessons learned from large-animal studies. Anesth Analg (2005) 1.08
Tissue oxygen and hemodynamics in renal medulla, cortex, and corticomedullary junction during hemorrhage-reperfusion. Am J Physiol Renal Physiol (2006) 1.07
Hazard Ratios and Hazardous Carbapenemase-Producing Enterobacteriaceae. Crit Care Med (2015) 1.06
Low-dose terlipressin during long-term hyperdynamic porcine endotoxemia: effects on hepatosplanchnic perfusion, oxygen exchange, and metabolism. Crit Care Med (2005) 1.05
Hyperglycemia in critical illness: a review. J Diabetes Sci Technol (2009) 1.04
Effect of increased cardiac output on hepatic and intestinal microcirculatory blood flow, oxygenation, and metabolism in hyperdynamic murine septic shock. Crit Care Med (2005) 1.01
N-acetylcysteine for sepsis and systemic inflammatory response in adults. Cochrane Database Syst Rev (2012) 1.00
Role of KATP channels in sepsis. Cardiovasc Res (2006) 1.00
Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective. Crit Care (2012) 1.00
Angiotensin II blockade augments renal cortical microvascular pO2 indicating a novel, potentially renoprotective action. Nephron Physiol (2003) 0.99
Inflammation biomarkers and delirium in critically ill patients. Crit Care (2014) 0.98
Comparison of cardiac, hepatic, and renal effects of arginine vasopressin and noradrenaline during porcine fecal peritonitis: a randomized controlled trial. Crit Care (2009) 0.98
Plasma disappearance of indocyanine green: a marker for excretory liver function? Intensive Care Med (2005) 0.98
Multivariate determination of 13CO2/12CO2 ratios in exhaled mouse breath with mid-infrared hollow waveguide gas sensors. Anal Bioanal Chem (2013) 0.96
Metabolic alterations in sepsis and vasoactive drug-related metabolic effects. Curr Opin Crit Care (2003) 0.96
Alteration of the sublingual microvascular glycocalyx in critically ill patients. Microvasc Res (2013) 0.96
Adrenomedullin binding improves catecholamine responsiveness and kidney function in resuscitated murine septic shock. Intensive Care Med Exp (2013) 0.96