Published in Stem Cells Int on December 07, 2015
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
The nuclear RNase III Drosha initiates microRNA processing. Nature (2003) 35.49
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet (2006) 20.76
The ground state of embryonic stem cell self-renewal. Nature (2008) 19.44
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell (2003) 17.72
The Microprocessor complex mediates the genesis of microRNAs. Nature (2004) 17.70
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
microRNA functions. Annu Rev Cell Dev Biol (2007) 15.74
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
Processing of primary microRNAs by the Microprocessor complex. Nature (2004) 14.59
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell (2003) 13.47
Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev (2005) 12.15
DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal. Nat Genet (2007) 9.25
Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14
Embryo-derived stem cells: of mice and men. Annu Rev Cell Dev Biol (2001) 6.76
Global transcription in pluripotent embryonic stem cells. Cell Stem Cell (2008) 5.81
FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. Development (2007) 5.62
Embryonic stem cell-specific microRNAs regulate the G1-S transition and promote rapid proliferation. Nat Genet (2008) 5.26
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA. Nucleic Acids Res (2010) 4.91
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell (2010) 3.60
Posttranscriptional crossregulation between Drosha and DGCR8. Cell (2009) 3.54
The ground state of pluripotency. Biochem Soc Trans (2010) 3.24
Small RNA-mediated regulation of iPS cell generation. EMBO J (2011) 2.95
A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. Development (2007) 2.92
BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages. Cell Stem Cell (2011) 2.79
NANOG-dependent function of TET1 and TET2 in establishment of pluripotency. Nature (2013) 2.63
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells (2007) 2.40
Ribonuclease revisited: structural insights into ribonuclease III family enzymes. Curr Opin Struct Biol (2006) 2.28
Control of ground-state pluripotency by allelic regulation of Nanog. Nature (2012) 2.25
PRDM14 ensures naive pluripotency through dual regulation of signaling and epigenetic pathways in mouse embryonic stem cells. Cell Stem Cell (2013) 1.96
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell (2012) 1.72
The Grb2/Mek pathway represses Nanog in murine embryonic stem cells. Mol Cell Biol (2006) 1.69
Oct4 links multiple epigenetic pathways to the pluripotency network. Cell Res (2011) 1.69
MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment. Circ Res (2012) 1.35
Small RNAs in early mammalian development: from gametes to gastrulation. Development (2011) 1.33
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4. Nat Struct Mol Biol (2012) 1.30
Phosphorylation of the RNase III enzyme Drosha at Serine300 or Serine302 is required for its nuclear localization. Nucleic Acids Res (2010) 1.19
Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile. Cell Rep (2013) 1.15
Glycogen synthase kinase 3 beta (GSK3β) phosphorylates the RNAase III enzyme Drosha at S300 and S302. PLoS One (2011) 1.09
PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells. Development (2013) 1.02
A PRC2-dependent repressive role of PRDM14 in human embryonic stem cells and induced pluripotent stem cell reprogramming. Stem Cells (2013) 1.01
Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells. Stem Cells (2011) 0.97
MicroRNA-181 regulates CARM1 and histone arginine methylation to promote differentiation of human embryonic stem cells. PLoS One (2013) 0.86
CHIR99021 promotes self-renewal of mouse embryonic stem cells by modulation of protein-encoding gene and long intergenic non-coding RNA expression. Exp Cell Res (2013) 0.85
AICAR sustains J1 mouse embryonic stem cell self-renewal and pluripotency by regulating transcription factor and epigenetic modulator expression. Cell Physiol Biochem (2013) 0.81
GSK3 inhibitors CHIR99021 and 6-bromoindirubin-3'-oxime inhibit microRNA maturation in mouse embryonic stem cells. Sci Rep (2015) 0.81
Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation. PLoS One (2013) 0.76