Published in Biochem Pharmacol on May 01, 1988
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Involvement of DNA topoisomerase I in transcription of human ribosomal RNA genes. Proc Natl Acad Sci U S A (1988) 2.29
Cloning and sequencing of cDNA encoding human DNA topoisomerase II and localization of the gene to chromosome region 17q21-22. Proc Natl Acad Sci U S A (1988) 2.26
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Purification and characterization of a type II DNA topoisomerase from bovine calf thymus. J Biol Chem (1985) 2.04
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Overexpression of RNase H partially complements the growth defect of an Escherichia coli delta topA mutant: R-loop formation is a major problem in the absence of DNA topoisomerase I. Proc Natl Acad Sci U S A (1995) 1.89
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Ubiquitin/26S proteasome-mediated degradation of topoisomerase I as a resistance mechanism to camptothecin in tumor cells. Cancer Res (2001) 1.63
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In vivo mapping of DNA topoisomerase II-specific cleavage sites on SV40 chromatin. Cell (1985) 1.57
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The basic domain of myogenic basic helix-loop-helix (bHLH) proteins is the novel target for direct inhibition by another bHLH protein, Twist. Mol Cell Biol (1997) 1.56
Identification of DNA topoisomerase II as an intracellular target of antitumor epipodophyllotoxins in simian virus 40-infected monkey cells. Cancer Res (1985) 1.53
In vivo localization of DNA topoisomerase II cleavage sites on Drosophila heat shock chromatin. Mol Cell Biol (1986) 1.52
26 S proteasome-mediated degradation of topoisomerase II cleavable complexes. J Biol Chem (2001) 1.50
Expression of alpha-amylases, carbohydrate metabolism, and autophagy in cultured rice cells is coordinately regulated by sugar nutrient. Plant J (1994) 1.49
SUMO-1 conjugation to human DNA topoisomerase II isozymes. J Biol Chem (2000) 1.48
Metabolic derepression of alpha-amylase gene expression in suspension-cultured cells of rice. J Biol Chem (1991) 1.48
SUMO-1 conjugation to topoisomerase I: A possible repair response to topoisomerase-mediated DNA damage. Proc Natl Acad Sci U S A (2000) 1.47
The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B. Cancer Res (1992) 1.42
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Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells. Cancer Res (1988) 1.41
Design of antineoplastic agents on the basis of the "2-phenylnaphthalene-type" structural pattern. 2. Synthesis and biological activity studies of benzo]b]naphtho[2,3-d]furan-6,11-dione derivatives. J Med Chem (1993) 1.41
DNA topoisomerase I-mediated DNA cleavage and cytotoxicity of camptothecin analogues. Cancer Res (1989) 1.40
DNA topoisomerases as anticancer drug targets. Adv Pharmacol (1990) 1.38
Transplanted LDL and mannose-6-phosphate receptor internalization signals promote high-efficiency endocytosis of the transferrin receptor. EMBO J (1991) 1.34
Systemic and mucosal protective immunity to pneumococcal surface protein A. Ann N Y Acad Sci (1996) 1.34
DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II. Cancer Res (1986) 1.33
DNA topoisomerase II-mediated interaction of doxorubicin and daunorubicin congeners with DNA. Cancer Res (1989) 1.31
Newly replicated DNA is associated with DNA topoisomerase II in cultured rat prostatic adenocarcinoma cells. Nature (1986) 1.31
Evidence for the reversibility of cellular DNA lesion induced by mammalian topoisomerase II poisons. J Biol Chem (1989) 1.31
Identification of the breakage-reunion subunit of T4 DNA topoisomerase. J Biol Chem (1984) 1.31
DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors. Proc Natl Acad Sci U S A (1993) 1.30
DNA rearrangement mediated by inverted repeats. Proc Natl Acad Sci U S A (1996) 1.30
Stimulation of topoisomerase II-mediated DNA damage via a mechanism involving protein thiolation. Biochemistry (2001) 1.29
Activation of topoisomerase II-mediated excision of chromosomal DNA loops during oxidative stress. Genes Dev (1999) 1.25
Template supercoiling during ATP-dependent DNA helix tracking: studies with simian virus 40 large tumor antigen. Proc Natl Acad Sci U S A (1989) 1.21
Camptothecin overcomes MDR1-mediated resistance in human KB carcinoma cells. Cancer Res (1991) 1.20
Sugars act as signal molecules and osmotica to regulate the expression of alpha-amylase genes and metabolic activities in germinating cereal grains. Plant Mol Biol (1996) 1.19
ATP-dependent partitioning of the DNA template into supercoiled domains by Escherichia coli UvrAB. Proc Natl Acad Sci U S A (1991) 1.18
A new mammalian DNA topoisomerase I poison Hoechst 33342: cytotoxicity and drug resistance in human cell cultures. Cancer Res (1993) 1.17
Hypernegative supercoiling of the DNA template during transcription elongation in vitro. J Biol Chem (1994) 1.16
Resistance of human leukemic and normal lymphocytes to drug-induced DNA cleavage and low levels of DNA topoisomerase II. Cancer Res (1988) 1.16
Elevated expression of DNA topoisomerase II in camptothecin-resistant human tumor cell lines. Cancer Res (1990) 1.16
Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance. Cancer Res (1990) 1.15
Periodic ZnO nanorod arrays defined by polystyrene microsphere self-assembled monolayers. Nano Lett (2006) 1.14
Nonhistone proteins HMG1 and HMG2 unwind DNA double helix. Nucleic Acids Res (1979) 1.13
Human DNA topoisomerase I is encoded by a single-copy gene that maps to chromosome region 20q12-13.2. Proc Natl Acad Sci U S A (1988) 1.11
Mutations of human topoisomerase II alpha affecting multidrug resistance and sensitivity. Biochemistry (1999) 1.10
Inversion/dimerization of plasmids mediated by inverted repeats. J Mol Biol (1999) 1.10
DNA looping alters local DNA conformation during transcription. J Mol Biol (1991) 1.08
Interaction between human topoisomerase I and a novel RING finger/arginine-serine protein. Nucleic Acids Res (1999) 1.07
In vitro functional characterization of bacterially expressed human fibroblast tropomyosin isoforms and their chimeric mutants. Cell Motil Cytoskeleton (1993) 1.05
A model for tumor cell killing by topoisomerase poisons. Cancer Cells (1990) 1.05