Published in Mol Cell Biol on April 01, 1985
Murine hematopoietic cells with pre-B or pre-B/myeloid characteristics are generated by in vitro transformation with retroviruses containing fes, ras, abl, and src oncogenes. J Exp Med (1986) 1.88
Ras-mediated cell cycle arrest is altered by nuclear oncogenes to induce Schwann cell transformation. EMBO J (1988) 1.80
Control of thrombopoietin-induced megakaryocytic differentiation by the mitogen-activated protein kinase pathway. Mol Cell Biol (1997) 1.29
A v-H-ras-dependent hemopoietic tumor model involving progression from a clonal stage of transformation competence to autocrine interleukin 3 production. Mol Cell Biol (1989) 1.10
Relationships between B cell and myeloid differentiation. Studies with a B lymphocyte progenitor line, HAFTL-1. J Exp Med (1988) 1.05
Pi, a pre-B-cell-specific enhancer element in the immunoglobulin heavy-chain enhancer. Mol Cell Biol (1993) 0.91
Association of v-Ha-ras transgene expression with development of erythroleukemia in Tg.AC transgenic mice. Am J Pathol (1998) 0.79
Expression of viral p21ras during acquisition of a transformed phenotype by rat adrenal cortex cells infected with Kirsten murine sarcoma virus. Mol Cell Biol (1986) 0.76
Cytochemical identification of monocytes and granulocytes. Am J Clin Pathol (1971) 20.35
Mechanism of activation of a human oncogene. Nature (1982) 12.09
A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene. Nature (1982) 11.92
Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells. J Virol (1969) 11.78
Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue. Nature (1983) 10.64
Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur J Immunol (1979) 10.51
Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class. J Virol (1976) 9.33
Serum and urinary lysozyme (muramidase) in monocytic and monomyelocytic leukemia. J Exp Med (1966) 9.20
Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family. J Virol (1982) 8.88
The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes. Nature (1981) 8.44
AN UNIDENTIFIED VIRUS WHICH CAUSES THE RAPID PRODUCTION OF TUMOURS IN MICE. Nature (1964) 6.96
Activation of the T24 bladder carcinoma transforming gene is linked to a single amino acid change. Nature (1982) 6.78
Mink cell line Mv 1 Lu (CCL 64). Focus formation and the generation of "nonproducer" transformed cell lines with murine and feline sarcoma viruses. Virology (1974) 6.53
Direct transformation of 3T3 cells by Abelson murine leukaemia virus. Nature (1975) 5.97
Functional macrophage cell lines transformed by Abelson leukemia virus. Cell (1978) 5.76
Chicken hematopoietic cells transformed by seven strains of defective avian leukemia viruses display three distinct phenotypes of differentiation. Cell (1979) 5.61
Amphotropic host range of naturally occuring wild mouse leukemia viruses. J Virol (1976) 5.43
Structure and activation of the human N-ras gene. Cell (1983) 5.25
A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus. J Exp Med (1976) 5.13
Characterization of murine sarcoma virus (Kirsten) transformation of mouse and human cells. J Gen Virol (1971) 5.01
Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester. Proc Natl Acad Sci U S A (1979) 4.98
Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1. Nature (1983) 4.44
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34
Nonproducer clones of murine sarcoma virus transformed BALB-3T3 cells. Virology (1970) 3.85
Nucleotide sequence of the p21 transforming protein of Harvey murine sarcoma virus. Science (1982) 3.55
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters. Science (1979) 3.06
The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell (1983) 3.00
Origin and functional properties of the major gene product of the Snyder-Theilen strain of feline sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.83
Radiommunoassays for the 70,000-molecular-weight glycoproteins of endogenous mouse type C viruses: viral antigen expression in normal mouse tissues and sera. J Virol (1976) 2.82
AVIAN VIRUS GROWTHS AND THEIR ETIOLOGIC AGENTS. Adv Cancer Res (1963) 2.35
Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion. Proc Natl Acad Sci U S A (1979) 2.17
BALB and Kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent balb/c mouse epidermal keratinocyte lines. Cell (1983) 2.17
Strain MC29 avian leukosis virus. Myelocytoma, endothelioma, and renal growths: pathomorphological and ultrastructural aspects. J Natl Cancer Inst (1967) 2.08
Characterization of temperature-sensitive mutants of murine leukemia virus. Virology (1973) 2.05
Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proc Natl Acad Sci U S A (1983) 2.04
Myeloid and erythroid neoplastic responses to avian defective leukemia viruses in chickens and in quail. Virology (1981) 1.89
Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice. J Virol (1980) 1.85
Markedly elevated levels of an endogenous sarc protein in a hemopoietic precursor cell line. Mol Cell Biol (1981) 1.83
Molecules stimulating early red cell, granulocyte, macrophage, and megakaryocyte precursors in culture: similarity in size, hydrophobicity, and charge. J Cell Physiol Suppl (1982) 1.77
Generation of BALB-MuSV and Ha-MuSC by type C virus transduction of homologous transforming genes from different species. Cell (1981) 1.73
Construction and isolation of a transforming murine retrovirus containing the src gene of Rous sarcoma virus. J Virol (1983) 1.63
Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1). J Immunol Methods (1981) 1.60
Response of hemopoietic cells to avian acute leukemia viruses: effects on the differentiation of the target cells. Cell (1979) 1.54
BALB- and Harvey-murine sarcoma virus transformation of a novel lymphoid progenitor cell. J Exp Med (1982) 1.42
Harvey and Kirsten sarcoma viruses promote the growth and differentiation of erythroid precursor cells in vitro. Cell (1981) 1.38
Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus. Proc Natl Acad Sci U S A (1984) 1.34
Response of bone marrow to MC29 avian leukosis virus in vitro. Cancer Res (1969) 1.30
Different lymphoid cell targets by transformation by replication-competent Moloney and Rauscher mouse leukemia viruses. Cell (1980) 1.25
Origin and partial characterization of Fc receptor-bearing cells found within experimental carcinomas and sarcomas. Int J Cancer (1975) 1.14
Origin and biological properties of a new BALB/c mouse sarcoma virus. J Virol (1978) 1.14
In vitro transformation of murine pre-B lymphoid cells by Snyder-Theilen feline sarcoma virus. J Virol (1983) 0.99
Retroviruses induce granulocyte-macrophage colony stimulating activity in fibroblasts. Nature (1982) 0.90
Identification by transfection of transforming sequences in DNA of human T-cell leukemias. Proc Natl Acad Sci U S A (1983) 0.88
Phenotypically distinct target cells for murine sarcoma virus and murine leukemia virus marrow transformation in vitro. J Natl Cancer Inst (1979) 0.84
Antibody production to the factor in human urine stimulating colony formation in vitro by bone marrow cells. Br J Haematol (1970) 0.82
Discussion of humoral erythropoietic factors. Ann N Y Acad Sci (1959) 0.79
Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells. J Virol (1969) 11.78
In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J Natl Cancer Inst (1973) 11.26
Development of 3T3-like lines from Balb-c mouse embryo cultures: transformation susceptibility to SV40. J Cell Physiol (1968) 10.54
Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science (1983) 9.06
Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science (1991) 8.68
A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res (1987) 7.43
Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells. Science (1971) 6.71
Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science (1985) 6.56
erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells. Science (1987) 6.36
Expression of cellular homologues of retroviral onc genes in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 5.80
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells. Cell (1987) 5.11
Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells. Nature (1982) 5.11
Purification and characterization of a newly identified growth factor specific for epithelial cells. Proc Natl Acad Sci U S A (1989) 5.10
Mast cell lines produce lymphokines in response to cross-linkage of Fc epsilon RI or to calcium ionophores. Nature (1989) 5.10
Characterization of murine sarcoma virus (Kirsten) transformation of mouse and human cells. J Gen Virol (1971) 5.01
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science (1989) 4.79
T24 human bladder carcinoma oncogene is an activated form of the normal human homologue of BALB- and Harvey-MSV transforming genes. Nature (1982) 4.54
Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene. Proc Natl Acad Sci U S A (1992) 4.50
Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells. Proc Natl Acad Sci U S A (1973) 4.39
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol (2001) 4.38
Differential expression of the amv gene in human hematopoietic cells. Proc Natl Acad Sci U S A (1982) 4.37
PDGF induction of tyrosine phosphorylation of GTPase activating protein. Nature (1989) 4.36
Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene. Nature (1983) 4.34
Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis. J Cell Biol (2000) 4.33
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors. Proc Natl Acad Sci U S A (1989) 4.17
gag Gene of mammalian type-C RNA tumour viruses. Nature (1976) 4.11
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas. Oncogene (1995) 4.10
Basis for the acquisition of malignant potential by mouse cells cultivated in vitro. Science (1968) 4.00
Nonproducer clones of murine sarcoma virus transformed BALB-3T3 cells. Virology (1970) 3.85
Separation of murine cellular and murine leukaemia virus DNA polymerases. Nat New Biol (1971) 3.71
Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop. Science (1991) 3.69
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product. Nature (1991) 3.68
Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res (1994) 3.54
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
RNA-dependent DNA polymerase activity in five RNA viruses: divalent cation requirements. Proc Natl Acad Sci U S A (1970) 3.25
Role of IRS-2 in insulin and cytokine signalling. Nature (1995) 3.23
Nucleotide sequence evidence for relationship of AIDS retrovirus to lentiviruses. Nature (1985) 3.13
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J Biol Chem (1994) 3.03
Structural and immunological similarities between simian sarcoma virus gene product(s) and human platelet-derived growth factor. Nature (1983) 3.01
Oncogenes in solid human tumours. Nature (1982) 3.00
Characterization of murine leukaemia virus-specific DNA present in normal mouse cells. Nat New Biol (1973) 2.98
Endogenous type-C RNA viruses of mammalian cells. Biochim Biophys Acta (1976) 2.95
Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis. Proc Natl Acad Sci U S A (1983) 2.95
Nucleotide sequence analysis of the transforming region and large terminal redundancies of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A (1980) 2.93
Radiommunoassays for the 70,000-molecular-weight glycoproteins of endogenous mouse type C viruses: viral antigen expression in normal mouse tissues and sera. J Virol (1976) 2.82
Isolation of temperature-sensitive mutants of murine leukemia virus. Virology (1972) 2.78
Molecular cloning of integrated simian sarcoma virus: genome organization of infectious DNA clones. Proc Natl Acad Sci U S A (1981) 2.74
Immunological characterization of primate C-type virus reverse transcriptases. Nat New Biol (1972) 2.73
Mouse leukemia virus: "spontaneous" release by mouse embryo cells after long-term in vitro cultivation. Proc Natl Acad Sci U S A (1969) 2.68
Immunological relationships of reverse transcriptases from ribonucleic acid tumor viruses. J Virol (1972) 2.65
Overexpression of protein kinase C-delta and -epsilon in NIH 3T3 cells induces opposite effects on growth, morphology, anchorage dependence, and tumorigenicity. J Biol Chem (1993) 2.62
Neoplastic transformation of mast cells by Abelson-MuLV: abrogation of IL-3 dependence by a nonautocrine mechanism. Cell (1985) 2.59
Complete nucleotide sequence and organization of the Moloney murine sarcoma virus genome. Science (1981) 2.51
BRCA1 regulates p53-dependent gene expression. Proc Natl Acad Sci U S A (1998) 2.50
Development of a highly efficient expression cDNA cloning system: application to oncogene isolation. Proc Natl Acad Sci U S A (1991) 2.48
Nature and distribution of feline sarcoma virus nucleotide sequences. J Virol (1979) 2.47
Novel source of 1,2-diacylglycerol elevated in cells transformed by Ha-ras oncogene. Nature (1987) 2.46
B cell stimulatory factor-1/interleukin-4 mRNA is expressed by normal and transformed mast cells. Cell (1987) 2.44
Properties of clonal lines of murine sarcoma virus transformed Balb-3T3 cells. Virology (1969) 2.40
RNA dependent DNA polymerase activity in mammalian cells. Nature (1971) 2.37
Genetic factors influencing C-type RNA virus induction. J Exp Med (1972) 2.36
Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci U S A (1997) 2.36
Abelson murine leukemia virus: molecular cloning of infectious integrated proviral DNA. Proc Natl Acad Sci U S A (1981) 2.34
Signal transduction through the EGF receptor transfected in IL-3-dependent hematopoietic cells. Science (1988) 2.29
Major pol gene progenitors in the evolution of oncoviruses. Science (1984) 2.28
Widespread natural occurrence of high titers of neutralizing antibodies to a specific class of endogenous mouse type-C virus. Proc Natl Acad Sci U S A (1974) 2.27
Molecular cloning of Moloney murine sarcoma virus: arrangement of virus-related sequences within the normal mouse genome. Proc Natl Acad Sci U S A (1979) 2.27
Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma viruses. Science (1985) 2.23
The 5' untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor. Mol Cell Biol (1988) 2.22
IRS-1: essential for insulin- and IL-4-stimulated mitogenesis in hematopoietic cells. Science (1993) 2.21
Efficient coupling with phosphatidylinositol 3-kinase, but not phospholipase C gamma or GTPase-activating protein, distinguishes ErbB-3 signaling from that of other ErbB/EGFR family members. Mol Cell Biol (1994) 2.20
Nucleotide sequence analysis of equine infectious anemia virus proviral DNA. Virology (1987) 2.19
Restriction enzyme analysis of mouse cellular type C viral DNA: emergence of new viral sequences in spontaneous AKR/J lymphomas. Proc Natl Acad Sci U S A (1979) 2.18
Segregation of loci for C-type virus induction in strains of mice with high and low incidence of leukemia. Science (1973) 2.17
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors. Cancer Res (1992) 2.17
BALB and Kirsten murine sarcoma viruses alter growth and differentiation of EGF-dependent balb/c mouse epidermal keratinocyte lines. Cell (1983) 2.17
Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling. J Biol Chem (1999) 2.12
Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. Proc Natl Acad Sci U S A (1997) 2.12
Distribution of three classes of endogenous type-C RNA viruses among inbred strains of mice. Virology (1975) 2.07
MyoD induces growth arrest independent of differentiation in normal and transformed cells. Proc Natl Acad Sci U S A (1990) 2.07
Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling. J Biol Chem (1999) 2.05
Characterization of temperature-sensitive mutants of murine leukemia virus. Virology (1973) 2.05
Transforming genes of human hematopoietic tumors: frequent detection of ras-related oncogenes whose activation appears to be independent of tumor phenotype. Proc Natl Acad Sci U S A (1983) 2.04
Activated oncogenes in B6C3F1 mouse liver tumors: implications for risk assessment. Science (1987) 2.03
Ha-ras oncogenes are activated by somatic alterations in human urinary tract tumours. Nature (1984) 1.99
The transforming gene of Moloney murine sarcoma virus. Nature (1979) 1.98
The BRCA2 gene product functionally interacts with p53 and RAD51. Proc Natl Acad Sci U S A (1998) 1.97
A genetic locus for inducibility of C-type in BALB-c cells: the effect of a nonlinked regulatory gene on detection of virus after chemical activation. Proc Natl Acad Sci U S A (1972) 1.97
Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proc Natl Acad Sci U S A (1997) 1.96
Murine sarcoma virus transformation of BALB-3T3 cells: lack of dependence on murine leukemia virus. Proc Natl Acad Sci U S A (1970) 1.96
Regulation of keratinocyte growth factor gene expression by interleukin 1. J Biol Chem (1994) 1.95
An efficient directional cloning system to construct cDNA libraries containing full-length inserts at high frequency. Gene (1989) 1.90
p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene (1999) 1.90
An IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growth. Cell (1994) 1.89
A new class of endogenous human retroviral genomes. Science (1985) 1.89