Published in Nucleic Acids Res on June 11, 1987
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Regulatory sequences involved in the promotion and termination of RNA transcription. Annu Rev Genet (1979) 54.83
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Transcription termination and 3' processing: the end is in site! Cell (1985) 17.46
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
Nucleotide sequences in Xenopus 5S DNA required for transcription termination. Cell (1981) 7.03
The primary transcription unit of the mouse beta-major globin gene. Cell (1981) 5.75
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
Alpha-Globin-gene switching during the development of chicken embryos: expression and chromosome structure. Cell (1981) 4.47
Termination of transcription in E. coli. Cell (1983) 4.42
Termination of transcription and its regulation in the tryptophan operon of E. coli. Cell (1981) 4.39
A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro. Nature (1985) 4.01
A transcription terminator located upstream of the mouse rDNA initiation site affects rRNA synthesis. Cell (1986) 3.75
Transcription terminates in yeast distal to a control sequence. Cell (1983) 3.40
Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin gene. EMBO J (1986) 3.25
Transcription of the polyoma virus genome: synthesis and cleavage of giant late polyoma-specific RNA. Proc Natl Acad Sci U S A (1971) 2.77
Sequences controlling in vitro transcription of SV40 promoters. EMBO J (1983) 2.65
In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites. J Biol Chem (1984) 2.58
Mode of regulation of immunoglobulin mu- and delta-chain expression varies during B-lymphocyte maturation. Cell (1984) 2.53
A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter. Cell (1986) 2.52
Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell (1984) 2.44
A transcriptional terminator is a novel element of the promoter of the mouse ribosomal RNA gene. Cell (1986) 2.42
Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites. Mol Cell Biol (1984) 2.35
Transcription termination within the E1A gene of adenovirus induced by insertion of the mouse beta-major globin terminator element. Cell (1985) 2.29
Purified RNA polymerase III accurately and efficiently terminates transcription of 5S RNA genes. Cell (1983) 2.28
Sequences responsible for transcription termination on a gene segment in Saccharomyces cerevisiae. Mol Cell Biol (1984) 2.25
Determination of fragment order through partial digests and multiple enzyme digests. Methods Enzymol (1980) 2.10
Pausing and premature termination of human RNA polymerase II during transcription of adenovirus in vivo and in vitro. Proc Natl Acad Sci U S A (1984) 2.08
Transcription of Simian virus 40 DNA in a HeLa whole cell extract. J Biol Chem (1981) 2.05
Mapping of transcription initiation and termination signals on Xenopus laevis ribosomal DNA. Proc Natl Acad Sci U S A (1982) 1.99
Simian virus 40 major late promoter: an upstream DNA sequence required for efficient in vitro transcription. Mol Cell Biol (1984) 1.94
A specific DNA sequence controls termination of transcription in the gastrin gene. Mol Cell Biol (1986) 1.88
Control of adenovirus late promoter expression in two human cell lines. Mol Cell Biol (1985) 1.66
Transcription of the mouse dihydrofolate reductase gene proceeds unabated through seven polyadenylation sites and terminates near a region of repeated DNA. Mol Cell Biol (1984) 1.55
Termination of the ovalbumin gene transcription. EMBO J (1984) 1.53
Gene expression in murine erythroleukemia cells. Transcriptional control and chromatin structure of the alpha 1-globin gene. J Mol Biol (1984) 1.46
RNA polymerase II transcription terminates at a specific DNA sequence in a HeLa cell-free reaction. Proc Natl Acad Sci U S A (1986) 1.39
Premature termination by human RNA polymerase II occurs temporally in the adenovirus major late transcriptional unit. Mol Cell Biol (1984) 1.30
Analysis of the expression of genes encoding animal mRNA by in vitro techniques. Prog Nucleic Acid Res Mol Biol (1983) 1.23
Tripartite sequences within and 3' to the sea urchin H2A histone gene display properties associated with a transcriptional termination process. Mol Cell Biol (1986) 1.22
Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine. Proc Natl Acad Sci U S A (1982) 1.07
Pausing and termination of human RNA polymerase II transcription at a procaryotic terminator. Mol Cell Biol (1983) 1.04
Extent of transcription of the E strand of polyoma virus DNA during the early phase of productive infection. J Virol (1978) 0.89
Effects of the adenovirus 2 late promoter on simian virus 40 transcription and replication. J Virol (1986) 0.89
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
STATs in oncogenesis. Oncogene (2000) 8.60
Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity (1999) 7.78
Mechanism and regulation of mRNA polyadenylation. Genes Dev (1997) 7.48
In vitro transcription of adenovirus. J Virol (1981) 7.06
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors. Nature (1994) 6.97
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein. Science (1995) 6.28
RNA polymerase II and the integration of nuclear events. Genes Dev (2000) 6.16
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell (1990) 5.92
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell (1991) 5.72
Transcriptional repression of eukaryotic promoters. Cell (1989) 5.60
The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell (1996) 4.93
RNA polymerase II is an essential mRNA polyadenylation factor. Nature (1998) 4.87
The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J (1995) 4.66
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J (1996) 4.65
Structure and in vitro transcription of human globin genes. Science (1980) 4.65
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature (2000) 4.36
Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol (1998) 4.22
In vitro transcription: whole-cell extract. Methods Enzymol (1983) 4.07
Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene (2001) 3.96
Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes Dev (1989) 3.95
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. Genes Dev (1997) 3.87
A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes Dev (1988) 3.80
Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression. J Clin Invest (2001) 3.79
The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell (1989) 3.77
STAT proteins: novel molecular targets for cancer drug discovery. Oncogene (2000) 3.75
RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A (1979) 3.75
Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate. Cell (1983) 3.68
A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev (1990) 3.43
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA. Nature (1997) 3.39
The ends of the affair: capping and polyadenylation. Nat Struct Biol (2000) 3.31
Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis. Proc Natl Acad Sci U S A (2001) 3.29
Phosphotyrosyl peptides block Stat3-mediated DNA binding activity, gene regulation, and cell transformation. J Biol Chem (2001) 3.27
Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation. Cell (1988) 3.16
Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation. Mol Cell (1998) 3.02
Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell (1989) 3.01
Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. Genes Dev (1999) 3.00
Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes Dev (1996) 2.99
Four factors are required for 3'-end cleavage of pre-mRNAs. Genes Dev (1989) 2.89
RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. J Mol Biol (1979) 2.86
Activating SRC mutation in a subset of advanced human colon cancers. Nat Genet (1999) 2.84
RNA recognition by the human polyadenylation factor CstF. Mol Cell Biol (1997) 2.84
The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. Genes Dev (1995) 2.83
Splicing-related catalysis by protein-free snRNAs. Nature (2001) 2.83
Functional domains of the human splicing factor ASF/SF2. EMBO J (1993) 2.83
AKT1/PKBalpha kinase is frequently elevated in human cancers and its constitutive activation is required for oncogenic transformation in NIH3T3 cells. Am J Pathol (2001) 2.81
Functional domains of the Drosophila Engrailed protein. EMBO J (1993) 2.73
Determinants of SR protein specificity. Curr Opin Cell Biol (1999) 2.72
Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing. Mol Cell Biol (1985) 2.68
Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. Genes Dev (1993) 2.67
Constitutive activation of Stat3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells. Cell Growth Differ (1997) 2.63
Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. RNA (1995) 2.60
In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites. J Biol Chem (1984) 2.58
Base substitution in an intervening sequence of a beta+-thalassemic human globin gene. Proc Natl Acad Sci U S A (1981) 2.58
The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms. Genes Dev (1998) 2.56
Complex protein interactions within the human polyadenylation machinery identify a novel component. Mol Cell Biol (2000) 2.55
Characterization of the multisubunit cleavage-polyadenylation specificity factor from calf thymus. J Biol Chem (1992) 2.51
Why is p53 acetylated? Cell (2001) 2.42
High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes Dev (1998) 2.40
Factors influencing alternative splice site utilization in vivo. Mol Cell Biol (1987) 2.39
Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2. EMBO J (1998) 2.37
Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proc Natl Acad Sci U S A (1997) 2.34
Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes Dev (1996) 2.33
Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA. Nature (1991) 2.30
A novel U2-U6 snRNA structure is necessary for mammalian mRNA splicing. Genes Dev (1995) 2.29
Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell (1998) 2.25
Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex. Mol Cell (2000) 2.21
Raf exists in a native heterocomplex with hsp90 and p50 that can be reconstituted in a cell-free system. J Biol Chem (1993) 2.17
The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proc Natl Acad Sci U S A (1992) 2.15
The human splicing factor ASF/SF2 can specifically recognize pre-mRNA 5' splice sites. Proc Natl Acad Sci U S A (1994) 2.14
Gene therapy with dominant-negative Stat3 suppresses growth of the murine melanoma B16 tumor in vivo. Cancer Res (1999) 2.09
The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing. Mol Cell Biol (1999) 2.09
TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters. Genes Dev (1992) 2.08
Induction of p21WAF1/CIP1 and cyclin D1 expression by the Src oncoprotein in mouse fibroblasts: role of activated STAT3 signaling. Oncogene (2000) 2.06
A polyadenylation factor subunit is the human homologue of the Drosophila suppressor of forked protein. Nature (1994) 2.03
Role of epidermal growth factor receptor and STAT-3 activation in autonomous proliferation of SUM-102PT human breast cancer cells. Cancer Res (1997) 1.97
The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression. Cell (2001) 1.95
The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes Dev (1992) 1.90
Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination. Mol Cell (2001) 1.85
Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing. Genes Dev (1998) 1.85
Primary structure and expression of bovine poly(A) polymerase. Nature (1991) 1.84
A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates. Mol Cell Biol (1990) 1.84
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro. Mol Cell Biol (1985) 1.81
Requirement for Ras/Rac1-mediated p38 and c-Jun N-terminal kinase signaling in Stat3 transcriptional activity induced by the Src oncoprotein. Mol Cell Biol (1999) 1.80
A CCAAT box sequence in the adenovirus major late promoter functions as part of an RNA polymerase II termination signal. Cell (1989) 1.80
U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements. Nucleic Acids Res (1995) 1.77
Activation of STAT transcription factors in oncogenic tyrosine kinase signaling. J Biomed Sci (1998) 1.77
Synthesis and degradation of termination and premature-termination fragments of beta-galactosidase in vitro and in vivo. J Mol Biol (1978) 1.76
Sequence specificity of the human mRNA N6-adenosine methylase in vitro. Nucleic Acids Res (1990) 1.73
Enzymatically inactive p60c-src mutant with altered ATP-binding site is fully phosphorylated in its carboxy-terminal regulatory region. Cell (1987) 1.71
Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DNA binding specificities. EMBO J (1992) 1.70
Selective translation initiation on bicistronic simian virus 40 late mRNA. J Virol (1987) 1.70
Cell-cycle related regulation of poly(A) polymerase by phosphorylation. Nature (1996) 1.69
Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPs. Cell (1984) 1.69
Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a). J Clin Invest (1993) 1.69
Generation and functional analyses for base-substitution mutants of the adenovirus 2 major late promoter. Nucleic Acids Res (1984) 1.68