Published in J Virol on December 01, 1981
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
The genome of minute virus of mice, an autonomous parvovirus, encodes two overlapping transcription units. Nucleic Acids Res (1983) 3.48
Regulation of human ribosomal RNA transcription. Proc Natl Acad Sci U S A (1983) 2.25
Human U2 small nuclear RNA genes contain an upstream enhancer. EMBO J (1986) 2.10
Sp1 activates transcription without enhancing DNA-binding activity of the TATA box factor. Mol Cell Biol (1989) 1.87
Generation and functional analyses for base-substitution mutants of the adenovirus 2 major late promoter. Nucleic Acids Res (1984) 1.68
In vitro transcription and delimitation of promoter elements of the murine dihydrofolate reductase gene. Mol Cell Biol (1986) 1.64
A stable transcription complex directs mouse ribosomal RNA synthesis by RNA polymerase I. Nucleic Acids Res (1983) 1.63
Identification of two transcription factors that bind to specific elements in the promoter of the adenovirus early-region 4. Mol Cell Biol (1988) 1.50
Cycloheximide stimulates early adenovirus transcription if early gene expression is allowed before treatment. J Virol (1983) 1.43
Far upstream initiation sites for adenovirus early region 1A transcription are utilized after the onset of viral DNA replication. J Virol (1983) 1.40
Proximal and distal domains that control in vitro transcription of the adenovirus IVa2 gene. Proc Natl Acad Sci U S A (1984) 1.30
Regulation of in vitro and in vivo transcription of early-region IV of adenovirus type 5 by multiple cis-acting elements. Mol Cell Biol (1987) 1.25
Adenovirus early region 1A protein increases the number of template molecules transcribed in cell-free extracts. Proc Natl Acad Sci U S A (1986) 1.23
NF-kappa B-mediated activation of the human immunodeficiency virus enhancer: site of transcriptional initiation is independent of the TATA box. J Virol (1989) 1.22
Both trans-acting factors and chromatin structure are involved in the regulation of transcription from the early and late promoters in simian virus 40 chromosomes. J Virol (1985) 1.15
Requirement for distal upstream sequences for maximal transcription in vitro of early region IV of adenovirus. Mol Cell Biol (1984) 1.12
Characterization of a surrogate TATA box promoter that regulates in vitro transcription of the simian virus 40 major late gene. Mol Cell Biol (1985) 1.03
The requirement for the A block promoter element in tRNA gene transcription in vitro depends on the ionic environment. Nucleic Acids Res (1987) 1.02
Homologous globin cell-free transcription system with comparison of heterologous factors. Mol Cell Biol (1984) 1.00
Positive and negative control sequences within the distal domain of the adenovirus IVa2 promoter overlap with the major late promoter. J Virol (1985) 0.96
Promoters of bovine papillomavirus type 1: in vitro activity and utilization. J Virol (1988) 0.95
Cis and trans activation of adenovirus IVa2 gene transcription. Nucleic Acids Res (1985) 0.94
Identification of a transcription factor which interacts with the distal domain of the adenovirus IVa2 promoter. J Virol (1987) 0.93
Transcription in the reverse orientation at either terminus of the adenovirus type 5 genome. EMBO J (1989) 0.88
Evidence that USF can interact with only a single general transcription complex at one time. Mol Cell Biol (1992) 0.87
Sequences upstream of c-mos(rat) that block RNA accumulation in mouse cells do not inhibit in vitro transcription. Mol Cell Biol (1985) 0.85
Conversion of simian virus 40 DNA to ordered nucleoprotein structures by extracts that direct accurate initiation by eukaryotic RNA polymerase II. Nucleic Acids Res (1982) 0.85
Transcription of adenovirus 5 early region 1b is elevated in permissive cells infected by a mutant with an upstream deletion. J Virol (1982) 0.81
The promoter for the late gene encoding Vp5 of herpes simplex virus type 1 is recognized by cell extracts derived from uninfected cells. J Virol (1986) 0.79
Unusual heterogeneity of the 5'-termini of human adenovirus type 2 early region E2 mRNA. Nucleic Acids Res (1984) 0.79
Specific transcription of preformed nucleoprotein complexes, containing the adenovirus major late promoter, with a chromatographic fraction containing RNA polymerase II. Proc Natl Acad Sci U S A (1985) 0.77
Delineation of DNA sequences that are important for in vitro transcription from the adenovirus EIIa late promoter. Mol Cell Biol (1988) 0.75
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
A two-dimensional fractionation procedure for radioactive nucleotides. J Mol Biol (1965) 20.83
Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA. Cell (1979) 19.98
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
Identification of regulatory sequences in the prelude sequences of an H2A histone gene by the study of specific deletion mutants in vivo. Proc Natl Acad Sci U S A (1980) 16.88
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Capping of eucaryotic mRNAs. Cell (1976) 10.84
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence. Proc Natl Acad Sci U S A (1980) 10.27
Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes. Nature (1980) 10.22
Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen. Proc Natl Acad Sci U S A (1980) 10.22
Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (1978) 9.60
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
Complex splicing patterns of RNAs from the early regions of adenovirus-2. J Mol Biol (1979) 7.53
Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. Proc Natl Acad Sci U S A (1981) 7.40
Spacer DNA sequences upstream of the T-A-T-A-A-A-T-A sequence are essential for promotion of H2A histone gene transcription in vivo. Proc Natl Acad Sci U S A (1980) 7.31
Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs. Proc Natl Acad Sci U S A (1981) 5.89
The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell (1980) 5.80
The SV40 early region TATA box is required for accurate in vitro initiation of transcription. Nature (1981) 5.43
Messenger RNA for the Ad2 DNA binding protein: DNA sequences encoding the first leader and heterogenity at the mRNA 5' end. Cell (1979) 5.28
DNA sequences preceding the rabbit beta-globin gene are required for formation in mouse L cells of beta-globin RNA with the correct 5' terminus. Proc Natl Acad Sci U S A (1981) 5.26
Promoters and heterogeneous 5' termini of the messenger RNAs of adenovirus serotype 2. J Mol Biol (1981) 5.01
Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing. Nature (1981) 4.46
Control of adenovirus early gene expression: a class of immediate early products. Cell (1980) 3.41
The nucleotide sequence of the transforming HpaI-E fragment of adenovirus type 5 DNA. Gene (1978) 3.36
Transcription and RNA processing by the DNA tumour viruses. Nature (1980) 3.25
Transcripts from the adenovirus-2 major late promoter yield a single early family of 3' coterminal mRNAs and five late families. Cell (1980) 3.21
RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. J Mol Biol (1979) 2.86
Nucleotide sequence of the EcoRI-F fragment of adenovirus 2 genome. Gene (1979) 2.17
Transcription of Simian virus 40 DNA in a HeLa whole cell extract. J Biol Chem (1981) 2.05
The nucleotide sequence of the right-hand terminus of adenovirus type 5 DNA: implications for the mechanism of DNA replication. Gene (1979) 1.60
Biogenesis, structures, and sites of encoding of the 5' termini of adenovirus-2 mRNAs. Cold Spring Harb Symp Quant Biol (1980) 1.52
Analysis of the sites of integration of viral DNA sequences in rat cells transformed by adenovirus 2 or SV40. Cold Spring Harb Symp Quant Biol (1980) 1.52
RNA transcription and splicing at early and intermediate times after adenovirus-2 infection. Cold Spring Harb Symp Quant Biol (1980) 1.48
The nucleotide sequence of adenovirus type 5 early region E1: the region between map positions 8.0 (HindIII site) and 11.8 (SmaI site). Gene (1980) 1.38
Adenovirus 2 early messenger RNA-genome mapping of 5'-terminal RNase T1 oligonucleotides and heterogeneity of 5'-termini. J Biol Chem (1980) 1.07
Unique species of mRNA from adenovirus type 7 early region 1 in cells transformed by adenovirus type 7 DNA fragment. J Virol (1980) 0.99
Nucleotide sequences, integration, and transcription of the adenovirus-12 transforming genes. Cold Spring Harb Symp Quant Biol (1980) 0.99
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry (1973) 43.61
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing. Cell (2001) 25.86
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (1984) 24.45
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
The rde-1 gene, RNA interference, and transposon silencing in C. elegans. Cell (1999) 13.48
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Specific interference by ingested dsRNA. Nature (1998) 11.82
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. Gene (2001) 11.09
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell (1985) 10.06
On the role of RNA amplification in dsRNA-triggered gene silencing. Cell (2001) 9.78
Coincidence of the promoter and capped 5' terminus of RNA from the adenovirus 2 major late transcription unit. Cell (1978) 9.60
DNA transformation. Methods Cell Biol (1995) 9.27
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
DNA sequence required for initiation of transcription in vitro from the major late promoter of adenovirus 2. Proc Natl Acad Sci U S A (1981) 9.08
Recognition of cap structure in splicing in vitro of mRNA precursors. Cell (1984) 8.67
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
Speculations on RNA splicing. Cell (1981) 8.28
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell (1986) 8.06
Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell (1988) 8.00
Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI. Proc Natl Acad Sci U S A (1973) 7.75
Splicing of messenger RNA precursors. Science (1987) 7.61
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev (1988) 7.52
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol Cell Biol (1986) 7.49
Mechanism and regulation of mRNA polyadenylation. Genes Dev (1997) 7.48
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes. Cell (1987) 7.44
Recognition by Max of its cognate DNA through a dimeric b/HLH/Z domain. Nature (1993) 7.41
Regulation by HIV Rev depends upon recognition of splice sites. Cell (1989) 7.13
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems. Proc Natl Acad Sci U S A (2001) 7.12
Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors. Nature (1994) 6.97
Structural and transcriptional analysis of human papillomavirus type 16 sequences in cervical carcinoma cell lines. J Virol (1987) 6.65
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
Evolutionary fates and origins of U12-type introns. Mol Cell (1998) 6.25
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
Presence and expression of human papillomavirus sequences in human cervical carcinoma cell lines. Am J Pathol (1985) 6.18
RNA polymerase II and the integration of nuclear events. Genes Dev (2000) 6.16
Distinct requirements for somatic and germline expression of a generally expressed Caernorhabditis elegans gene. Genetics (1997) 6.08
A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell (1990) 5.92
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (1992) 5.87
Human CCAAT-binding proteins have heterologous subunits. Cell (1988) 5.81
A high-efficiency HeLa cell nuclear transcription extract. DNA (1988) 5.81
Association of Myn, the murine homolog of max, with c-Myc stimulates methylation-sensitive DNA binding and ras cotransformation. Cell (1991) 5.76
Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell (1991) 5.72
Transcriptional repression of eukaryotic promoters. Cell (1989) 5.60
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Messenger RNA for the Ad2 DNA binding protein: DNA sequences encoding the first leader and heterogenity at the mRNA 5' end. Cell (1979) 5.28
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
Functional anatomy of a dsRNA trigger: differential requirement for the two trigger strands in RNA interference. Mol Cell (2000) 5.18
Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science (1984) 5.11
Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription. Mol Cell Biol (1986) 5.07
Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Mol Cell Biol (1987) 5.05
Promoters and heterogeneous 5' termini of the messenger RNAs of adenovirus serotype 2. J Mol Biol (1981) 5.01
The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell (1996) 4.93
RNA polymerase II is an essential mRNA polyadenylation factor. Nature (1998) 4.87
Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J Biol Chem (1985) 4.87
Mapping of adenovirus 2 RNA sequences in lytically infected cells and transformed cell lines. Cold Spring Harb Symp Quant Biol (1975) 4.87
Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. Proc Natl Acad Sci U S A (1988) 4.83
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
Separation and characterization of factors mediating accurate transcription by RNA polymerase II. J Biol Chem (1982) 4.71
On the origin of RNA splicing and introns. Cell (1985) 4.70
Sequence heterogeneity in closed simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.69
Splicing of adenovirus RNA in a cell-free transcription system. Proc Natl Acad Sci U S A (1983) 4.69
The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. EMBO J (1995) 4.66
The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. EMBO J (1996) 4.65
Structure and in vitro transcription of human globin genes. Science (1980) 4.65
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans. Proc Natl Acad Sci U S A (1998) 4.63
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
Methylation-sensitive sequence-specific DNA binding by the c-Myc basic region. Science (1991) 4.45
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature (1982) 4.42
Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature (2000) 4.36
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HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J (1991) 4.18
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In vitro transcription: whole-cell extract. Methods Enzymol (1983) 4.07
Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome. Science (1986) 4.01
Messenger RNA splicing in vitro: an excised intervening sequence and a potential intermediate. Cell (1984) 4.00
Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes Dev (1989) 3.95
An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene (1977) 3.94
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
Cleavage maps of DNA from adenovirus types 2 and 5 by restriction endonucleases EcoRI and HpaI. Cold Spring Harb Symp Quant Biol (1975) 3.87
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. Genes Dev (1997) 3.87