Published in J Exp Med on June 16, 1997
Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide. J Exp Med (2003) 4.96
Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci U S A (2006) 3.70
Interleukin 15 controls both proliferation and survival of a subset of memory-phenotype CD8(+) T cells. J Exp Med (2002) 3.20
TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci U S A (2004) 3.04
Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc Natl Acad Sci U S A (2006) 3.04
Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol (2005) 2.97
Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med (1998) 2.58
Disruption of T cell homeostasis in mice expressing a T cell-specific dominant negative transforming growth factor beta II receptor. J Exp Med (2000) 2.45
Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice. J Exp Med (1999) 2.33
Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease. J Clin Invest (1998) 2.14
LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation. J Clin Invest (2001) 1.91
Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought. J Virol (2006) 1.78
Tracking the total CD8 T cell response to infection reveals substantial discordance in magnitude and kinetics between inbred and outbred hosts. J Immunol (2009) 1.68
NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells. Nat Immunol (2012) 1.62
Qualitative differences between naïve and memory T cells. Immunology (2002) 1.48
Purified lipopolysaccharide from Francisella tularensis live vaccine strain (LVS) induces protective immunity against LVS infection that requires B cells and gamma interferon. Infect Immun (2000) 1.42
Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection. J Immunol (2010) 1.42
Ageing is associated with a prolonged fever response in human endotoxemia. Clin Diagn Lab Immunol (2001) 1.37
Cytokine-mediated programmed proliferation of virus-specific CD8(+) memory T cells. Immunity (2012) 1.31
Enhanced antitumor immunity in mice deficient in CD69. J Exp Med (2003) 1.29
T-cell proliferation in vivo and the role of cytokines. Philos Trans R Soc Lond B Biol Sci (2000) 1.25
CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood (2007) 1.25
Impact of human immunodeficiency virus 1 infection and inflammation on the composition and yield of cervical mononuclear cells in the female genital tract. Immunology (2009) 1.21
Antigen-dependent and -independent mechanisms of T and B cell hyperactivation during chronic HIV-1 infection. J Virol (2011) 1.17
The T cell STAT signaling network is reprogrammed within hours of bacteremia via secondary signals. J Immunol (2009) 1.11
O-antigen-negative Salmonella enterica serovar Typhimurium is attenuated in intestinal colonization but elicits colitis in streptomycin-treated mice. Infect Immun (2009) 1.10
Granzyme B production distinguishes recently activated CD8(+) memory cells from resting memory cells. Cell Immunol (2007) 1.08
Ligation of the OX40 co-stimulatory receptor reverses self-Ag and tumor-induced CD8 T-cell anergy in vivo. Eur J Immunol (2009) 1.03
The VP7 outer capsid protein of rotavirus induces polyclonal B-cell activation. J Virol (2004) 1.01
Understanding how lipopolysaccharide impacts CD4 T-cell immunity. Crit Rev Immunol (2008) 0.96
Human immune memory to yellow fever and smallpox vaccination. J Clin Immunol (2008) 0.95
Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice. Clin Exp Immunol (2005) 0.89
The role of TLR4 activation in photoreceptor mitochondrial oxidative stress. Invest Ophthalmol Vis Sci (2011) 0.88
Lipopolysaccharide stimulates butyric acid-induced apoptosis in human peripheral blood mononuclear cells. Infect Immun (1999) 0.87
The innate immune response affects the development of the autoimmune response in Theiler's virus-induced demyelinating disease. J Immunol (2009) 0.86
A toll for T cell costimulation. Ann Rheum Dis (2004) 0.86
Soluble tumour necrosis factor (TNF)-receptor levels in serum as markers of anti-viral host reactivity. Clin Exp Immunol (1999) 0.85
Preactivation of B lymphocytes does not enhance mouse mammary tumor virus infection. J Virol (1998) 0.84
Helicobacter pylori with a truncated lipopolysaccharide O chain fails to induce gastritis in SCID mice injected with splenocytes from wild-type C57BL/6J mice. Infect Immun (2004) 0.84
Human peripheral blood T cells, monocytes, and macrophages secrete macrophage inflammatory proteins 1alpha and 1beta following stimulation with heat-inactivated Brucella abortus. Infect Immun (2001) 0.84
A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens. J Immune Based Ther Vaccines (2006) 0.84
Role of dendritic cells in the immune response induced by mouse mammary tumor virus superantigen. J Virol (1999) 0.83
Differential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with interleukin-6 production. J Pharmacol Exp Ther (2013) 0.82
Structural modifications of Helicobacter pylori lipopolysaccharide: an idea for how to live in peace. World J Gastroenterol (2014) 0.81
CCR7 expression alters memory CD8 T-cell homeostasis by regulating occupancy in IL-7- and IL-15-dependent niches. Proc Natl Acad Sci U S A (2016) 0.81
Low concentrations of lipopolysaccharide synergize with peptides to augment human T-cell proliferation and can prevent the induction of non-responsiveness by CTLA4-Ig. Immunology (2001) 0.81
Impact of antigen specificity on CD4+ T cell activation in chronic HIV-1 infection. BMC Infect Dis (2013) 0.81
Characterization of a novel subset of CD8(+) T cells that expands in patients receiving interleukin-12. J Clin Invest (1998) 0.80
Attrition of memory CD8 T cells during sepsis requires LFA-1. J Leukoc Biol (2016) 0.80
Dermal exposure to immunostimulants induces changes in activity and proliferation of coelomocytes of Eisenia andrei. J Comp Physiol B (2012) 0.79
The prevention of colorectal anastomotic leakage with tissue adhesives in a contaminated environment is associated with the presence of anti-inflammatory macrophages. Int J Colorectal Dis (2014) 0.79
Changes of ribosomal protein S3 immunoreactivity and its new expression in microglia in the mice hippocampus after lipopolysaccharide treatment. Cell Mol Neurobiol (2012) 0.78
Polymyxins as novel and safe mucosal adjuvants to induce humoral immune responses in mice. PLoS One (2013) 0.78
Complement receptors regulate lipopolysaccharide-induced T-cell stimulation. Immunology (2005) 0.78
Regulation of TB vaccine-induced airway luminal T cells by respiratory exposure to endotoxin. PLoS One (2012) 0.77
The role of bystander T cells in CNS pathology and pathogen clearance. Crit Rev Immunol (2005) 0.77
Infection as an Environmental Trigger of Multiple Sclerosis Disease Exacerbation. Front Immunol (2015) 0.76
Chemotactic and immunoregulatory properties of bone cells are modulated by endotoxin-stimulated lymphocytes. Inflammation (2012) 0.76
Lung function early after lung transplantation is correlated with the frequency of regulatory T cells. Surg Today (2011) 0.76
Unresolved issues in theories of autoimmune disease using myocarditis as a framework. J Theor Biol (2014) 0.75
Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice. J Neuroimmunol (2007) 0.75
IFNγ influences type I interferon response and susceptibility to Theiler's virus-induced demyelinating disease. Viral Immunol (2013) 0.75
Full activation of CD4+ T cells early during sepsis requires specific antigen. Shock (2015) 0.75
Change of calbindin D-28k protein expression in the mice hippocampus after lipopolysaccharide treatment. J Vet Med Sci (2014) 0.75
Altered T Lymphocyte Proliferation upon Lipopolysaccharide Challenge Ex Vivo. PLoS One (2015) 0.75
Optimal CD4 T cell priming after LPS-based adjuvanticity with CD134 costimulation relies on CXCL9 production. J Leukoc Biol (2017) 0.75
Functional role of type I and type II interferons in antiviral defense. Science (1994) 18.92
Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med (1992) 8.27
Turnover of naive- and memory-phenotype T cells. J Exp Med (1994) 8.07
Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science (1996) 7.00
Biochemistry of endotoxins. Annu Rev Biochem (1990) 6.75
Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science (1994) 6.65
Naive and memory T cells show distinct pathways of lymphocyte recirculation. J Exp Med (1990) 5.54
PPD tuberculin--a B-cell mitogen. Nat New Biol (1972) 4.70
On immunological memory. Annu Rev Immunol (1996) 3.21
Lymphocyte life-span and memory. Science (1994) 2.99
Activation of T and B lymphocytes in vitro. I. Regulatory influence of bacterial lipopolysaccharide (LPS) on specific T-cell helper function. J Exp Med (1974) 2.90
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J Exp Med (1985) 2.79
Cachectin/tumor necrosis factor exerts endocrine, paracrine, and autocrine control of inflammatory responses. J Cell Biol (1988) 2.66
High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response. J Exp Med (1993) 2.20
Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation. J Immunol (1988) 2.17
Virus-induced polyclonal cytotoxic T lymphocyte stimulation. J Immunol (1989) 2.13
Activation of cytokine genes in T cells during primary and secondary murine influenza pneumonia. J Exp Med (1993) 1.98
Lifespans of naive, memory and effector lymphocytes. Curr Opin Immunol (1993) 1.82
Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens. J Exp Med (1979) 1.73
Endotoxin-induced T lymphocyte proliferation. J Immunol (1983) 1.51
Induction of IFN-gamma in macrophages by lipopolysaccharide. Int Immunol (1993) 1.50
Activation of naive and memory T cells by interleukin-15. Blood (1996) 1.29
Interferon-alpha/beta enhances the expression of Ly-6 antigens on T cells in vivo and in vitro. Eur J Immunol (1986) 1.24
T cell regulation of polyclonal B cell responsiveness. I. Helper effects of T cells. J Immunol (1979) 1.21
Studies on the expression of spontaneous and induced interferons in mouse peritoneal macrophages by means of monoclonal antibodies to mouse interferons. J Gen Virol (1987) 1.14
Novel insight into molecular mechanism of endotoxin shock: biochemical analysis of LPS receptor signaling in a cell-free system targeting NF-kappaB and regulation of cytokine production/action through beta2 integrin in vivo. J Leukoc Biol (1996) 1.01
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity (1998) 9.02
Turnover of naive- and memory-phenotype T cells. J Exp Med (1994) 8.07
A receptor for antibody on B lymphocytes. I. Method of detection and functional significance. J Exp Med (1972) 7.47
Induction of bystander T cell proliferation by viruses and type I interferon in vivo. Science (1996) 7.00
IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A (2001) 6.91
Extrathymic tolerance of mature T cells: clonal elimination as a consequence of immunity. Cell (1990) 6.33
T-cell apoptosis detected in situ during positive and negative selection in the thymus. Nature (1994) 6.20
A monoclonal antibody discriminating between subsets of T and B cells. J Immunol (1981) 6.15
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. Immunity (1999) 6.10
Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science (1990) 4.92
Circulating T and B lymphocytes of the mouse. I. Migratory properties. Cell Immunol (1973) 3.53
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow. J Exp Med (1978) 3.46
Carpal tunnel syndrome in Rochester, Minnesota, 1961 to 1980. Neurology (1988) 3.40
Antigen-induced selective recruitment of circulating lymphocytes. Cell Immunol (1971) 3.35
Quantitative features of a sandwich radioimmunolabeling technique for lymphocyte surface receptors. J Exp Med (1972) 3.28
Cell-to-cell interaction in the immune response. VI. Contribution of thymus-derived cells and antibody-forming cell precursors to immunological memory. J Exp Med (1971) 3.14
Interaction between lymphocytes in immune responses. Cell Immunol (1971) 3.03
Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras. J Exp Med (1975) 3.03
T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol (1987) 2.93
Reentry of T cells to the adult thymus is restricted to activated T cells. J Exp Med (1991) 2.81
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens. J Exp Med (1985) 2.79
Cell-to-cell interaction in the immune response. X. T-cell-dependent suppression in tolerant mice. J Exp Med (1974) 2.77
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
Ecological genomics of marine Roseobacters. Appl Environ Microbiol (2007) 2.68
A defect in central tolerance in NOD mice. Nat Immunol (2001) 2.59
Type I interferon-mediated stimulation of T cells by CpG DNA. J Exp Med (1998) 2.58
Homeostatic T cell proliferation: how far can T cells be activated to self-ligands? J Exp Med (2000) 2.55
Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain. J Exp Med (1975) 2.39
Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras. J Exp Med (1975) 2.29
Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences. J Exp Med (1986) 2.29
Apoptosis of airway epithelial cells induced by corticosteroids. Am J Respir Crit Care Med (2001) 2.28
Activation of thymus cells by histocompatibility antigens. Nat New Biol (1971) 2.26
A radiation hybrid map of the cat genome: implications for comparative mapping. Genome Res (2000) 2.22
Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complex. J Exp Med (1978) 2.17
Identity of cells that imprint H-2-restricted T-cell specificity in the thymus. Nature (1986) 2.11
Thymus-derived cells in mouse thoracic duct lymph. Nat New Biol (1971) 2.07
Airway protection during experimental CPR. Chest (1995) 1.96
Role of H-2 gene products in the function of T helper cells from normal and chimeric mice in vivo. Immunol Rev (1978) 1.95
Metal ion catalysis during splicing of premessenger RNA. Nature (1997) 1.94
Circulating T and B lymphocytes of the mouse. II. Lifespan. Cell Immunol (1973) 1.94
Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium. Cell Immunol (1976) 1.89
T cells can use either T cell receptor or CD28 receptors to absorb and internalize cell surface molecules derived from antigen-presenting cells. J Exp Med (2000) 1.88
Receptor for antibody-antigen complexes used to separate T cells from B cells. Nat New Biol (1972) 1.87
Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. J Neuroimmunol (2001) 1.85
Protein-energy undernutrition among elderly hospitalized patients: a prospective study. JAMA (1999) 1.83
A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion. Immunogenetics (1981) 1.83
Volumetric MRI vs clinical predictors of Alzheimer disease in mild cognitive impairment. Neurology (2008) 1.80
Surface immunoglobulins on thymus and thymus-derived lymphoid cells. J Exp Med (1971) 1.79
Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells. Cell Immunol (1972) 1.78
Negative selection in the thymus includes semimature T cells. J Exp Med (1997) 1.77
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens. J Exp Med (1977) 1.75
Abnormal differentiation of thymocytes in mice treated with cyclosporin A. Nature (1988) 1.73
Requirements for peptide-induced T cell receptor downregulation on naive CD8+ T cells. J Exp Med (1997) 1.70
Three metal ions at the active site of the Tetrahymena group I ribozyme. Proc Natl Acad Sci U S A (1999) 1.69
Epinephrine increases the severity of postresuscitation myocardial dysfunction. Circulation (1995) 1.68
Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. Cell Immunol (1972) 1.68
Transcription factor E2 regulates BPV-1 DNA replication in vitro by direct protein-protein interaction. Cold Spring Harb Symp Quant Biol (1991) 1.67
Extensive conservation of sex chromosome organization between cat and human revealed by parallel radiation hybrid mapping. Genome Res (1999) 1.64
Iron oxide nanoparticle platform for biomedical applications. Curr Med Chem (2009) 1.63
Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen-presenting cells in vivo. J Exp Med (1992) 1.61
Two subsets of epithelial cells in the thymic medulla. J Exp Med (1992) 1.59
Upregulation of surface markers on dying thymocytes. J Exp Med (1995) 1.59
Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements. J Exp Med (1980) 1.59
Effect of recent antigen priming on adoptive immune responses. I. Specific unresponsiveness of cells from lymphoid organs of mice primed with heterologous erythrocytes. J Exp Med (1973) 1.58
Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo. J Exp Med (1989) 1.58
Five types of lymphocytes (Ig-theta-, Ig-theta+weak, Ig-theta+strong, Ig+theta- and Ig+theta+) characterized by double immunofluorescence and electrophoretic mobility. Organ distribution in normal and nude mice. Eur J Immunol (1975) 1.54
Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy. J Exp Med (1990) 1.54
Neonatal effects and serum cortisol levels after multiple courses of maternal corticosteroids. Obstet Gynecol (1997) 1.53
Second-generation integrated genetic linkage/radiation hybrid maps of the domestic cat (Felis catus). J Hered (2003) 1.53
Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences. J Immunol (1985) 1.51
The effects of biphasic and conventional monophasic defibrillation on postresuscitation myocardial function. J Am Coll Cardiol (1999) 1.50
Lifespan of gamma/delta T cells. J Exp Med (1998) 1.49
T cell function in bone marrow chimeras: absence of host-reactive T cells and cooperation of helper T cells across allogeneic barriers. Transplant Rev (1976) 1.49
Interaction of thymus lymphocytes with histoincompatible cells. 3. Immunological characteristics of recirculating lymphocytes derived from activated thymus cells. Cell Immunol (1972) 1.49
Cryo-electron energy loss spectroscopy: observations on vitrified hydrated specimens and radiation damage. Ultramicroscopy (1995) 1.48
Oxygen transport in tibetan women during pregnancy at 3,658 m. Am J Phys Anthropol (2001) 1.48
Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells. Science (1990) 1.47
Cell-to-cell interaction in the immune response. VII. Requirement for differentiation of thymus-derived cells. J Exp Med (1971) 1.46
Pulmonary ventilation/perfusion defects induced by epinephrine during cardiopulmonary resuscitation. Circulation (1991) 1.46
Smaller alveolar-arterial O2 gradients in Tibetan than Han residents of Lhasa (3658 m). Respir Physiol (1996) 1.45
Increasing prevalence of gestational diabetes mellitus in Chinese women from 1999 to 2008. Diabet Med (2011) 1.43
Internal carotid arterial flow velocity during exercise in Tibetan and Han residents of Lhasa (3,658 m). J Appl Physiol (1985) (1992) 1.43
Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer. Am J Hum Genet (1997) 1.42
DNA as an adjuvant: capacity of insect DNA and synthetic oligodeoxynucleotides to augment T cell responses to specific antigen. J Exp Med (1998) 1.41
Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice. J Exp Med (1987) 1.41
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection. Mucosal Immunol (2012) 1.39
An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. J Immunol (2001) 1.38
Antigen-induced selective recruitment of circulating lymphocytes. 1971. J Immunol (2006) 1.37
Transgenic HLA-DR alpha faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to E alpha in E alpha 0 mutant mice. Cell (1989) 1.37
Functions of purified L3T4+ and Lyt-2+ cells in vitro and in vivo. Immunol Rev (1986) 1.36
High-energy defibrillation increases the severity of postresuscitation myocardial dysfunction. Circulation (1997) 1.36
A novel class II MHC molecule with unusual tissue distribution. Nature (1991) 1.33
Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes. J Exp Med (1975) 1.32
Radiosensitivity of T and B lymphocytes. I. Effect of irradiation on cell migration. Eur J Immunol (1974) 1.31
Structures of normal single-stranded DNA and deoxyribo-3'-S-phosphorothiolates bound to the 3'-5' exonucleolytic active site of DNA polymerase I from Escherichia coli. Biochemistry (1999) 1.31
Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells. J Exp Med (1992) 1.30