Published in Immunol Today on April 01, 1988
Idiotypes and anti-idiotypes: what are they trying to tell us? Ann Rheum Dis (1988) 0.79
Oral immunization with xenogeneic antibodies stimulates the production of systemic and mucosal anti-idiotypic antibodies. Immunology (1991) 0.75
Cross-idiotypic specificity among monoclonal IgM proteins with anti- -globulin activity. J Exp Med (1973) 4.93
Analysis of somatic mutation in five B cell subsets of human tonsil. J Exp Med (1994) 4.52
Antigenic specificities related to the cold agglutinin activity of gamma M globulins. Science (1968) 4.32
Interaction of cell-type-specific nuclear proteins with immunoglobulin VH promoter region sequences. Nature (1986) 4.21
Oligomeric structure of gp41, the transmembrane protein of human immunodeficiency virus type 1. J Virol (1989) 4.07
Defining criteria for autoimmune diseases (Witebsky's postulates revisited) Immunol Today (1993) 3.81
Automated amino acid sequence of small peptides utilizing Polybrene. Anal Biochem (1978) 3.48
Neisseria gonorrhoeae and neisseria meningitidis: extracellular enzyme cleaves human immunoglobulin A. Science (1975) 3.27
HLA-DQ and T-cell receptor genes in insulin-dependent diabetes mellitus. Cold Spring Harb Symp Quant Biol (1986) 3.15
Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature (1998) 3.11
Initial characterization of monoclonal antibodies against human monocytes. Proc Natl Acad Sci U S A (1980) 2.61
Similarities in the light chains of anti-gamma-globulins showing cross-idiotypic specificities. J Exp Med (1974) 2.60
Cellular basis of regulation of expression of idiotype. I. T-suppressor cells specific for MOPC 460 idiotype regulate the expression of cells secreting anti-TNP antibodies bearing 460 idiotype. J Exp Med (1979) 2.53
Somatic hypermutation introduces insertions and deletions into immunoglobulin V genes. J Exp Med (1998) 2.39
Aggregation of gamma-G3 proteins: relevance to the hyperviscosity syndrome. J Clin Invest (1970) 2.19
Organization of the immune response genes. Science (1979) 2.18
Mitogenic effect of bacterial peptidoglycans possessing adjuvant activity. J Immunol (1975) 2.15
The smaller human VH gene families display remarkably little polymorphism. EMBO J (1989) 2.15
Subunit structure and N-terminal amino acid sequence of the three chains of cholera enterotoxin. Immunochemistry (1976) 2.14
Hypervariable regions, idiotypy, and the antibody-combining site. Adv Immunol (1975) 1.99
Presentation of a viral T cell epitope expressed in the CDR3 region of a self immunoglobulin molecule. Science (1993) 1.96
Differential susceptibility of human IgA immunoglobulins to streptococcal IgA protease. J Clin Invest (1974) 1.91
Influenza A virus transfectants with chimeric hemagglutinins containing epitopes from different subtypes. J Virol (1992) 1.88
Nucleotide sequences of eight human natural autoantibody VH regions reveals apparent restricted use of VH families. J Immunol (1989) 1.88
The amino acid sequence of ragweed pollen allergen Ra5. Biochemistry (1975) 1.85
Structure of antibodies with shared idiotypy: the complete sequence of the heavy chain variable regions of two immunoglobulin M anti-gamma globulins. Proc Natl Acad Sci U S A (1974) 1.84
The protein products of the murine 17th chromosome: genetics and structure. Adv Immunol (1978) 1.76
Cellular basis of regulation of expression of idiotype. II. Immunity to anti-MOPC-460 idiotype antibodies increases the level of anti-trinitrophenyl antibodies bearing 460 idiotypes. J Exp Med (1979) 1.76
Alpha and beta chains of SB and DR antigens are structurally distinct. J Exp Med (1982) 1.76
Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus. N Engl J Med (1990) 1.74
Amino acid sequence of ragweed allergen Ra3. Biochemistry (1980) 1.71
Structure-function relationships among anti-gamma globulin antibodies. Ann N Y Acad Sci (1971) 1.71
Chimeric influenza virus induces neutralizing antibodies and cytotoxic T cells against human immunodeficiency virus type 1. J Virol (1993) 1.70
Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation. J Exp Med (1979) 1.70
Human immunoglobulin heavy-chain variable region genes: organization, polymorphism, and expression. Adv Immunol (1991) 1.68
Light chain sequences of human IgM cold agglutinins (variable-region subgroups amino-acid sequence-kappa light chain-N-terminal). Proc Natl Acad Sci U S A (1972) 1.64
Blastic transformtion of mouse spleen lymphocytes by a water-soluble mitogen extracted from Nocardia. Proc Natl Acad Sci U S A (1974) 1.62
Complete amino acid sequence of variable domains from two monoclonal human anti-gamma globulins of the Wa cross-idiotypic group: suggestion that the J segments are involved in the structural correlate of the idiotype. Proc Natl Acad Sci U S A (1981) 1.60
Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes. J Exp Med (2000) 1.59
Immune response to levan. I. Kinetics and ontogeny of anti-levan and anti-inulin antibody response and of expression of cross-reactive idiotype. J Immunol (1978) 1.57
NonO, a non-POU-domain-containing, octamer-binding protein, is the mammalian homolog of Drosophila nonAdiss. Mol Cell Biol (1993) 1.57
Proteases as mitogens. The Effect of trypsin and pronase on mouse and human lymphocytes. Exp Cell Res (1974) 1.56
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype. J Immunol (1991) 1.56
Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue. J Immunol (1992) 1.55
A new human immunoglobulin VH family preferentially rearranged in immature B-cell tumours. Nature (1988) 1.55
Isolation of mitogenic and adjuvant active fractions from various species of Nocardiae. Infect Immun (1975) 1.54
V kappa and J kappa gene segments of A/J Ars-A antibodies: somatic recombination generates the essential arginine at the junction of the variable and joining regions. Proc Natl Acad Sci U S A (1987) 1.53
Variable region sequences of five human immunoglobulin heavy chains of the VH3 subgroup: definitive identification of four heavy chain hypervariable regions. Proc Natl Acad Sci U S A (1974) 1.52
VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities. J Immunol (1992) 1.52
Heterogeneity of an intrastrain cross-reactive idiotype associated with anti-p-azophenylarsonate antibodies of A/J mice. J Immunol (1980) 1.51
Identification of a new V kappa gene family that is highly expressed in hybridomas from an autoimmune mouse strain. J Immunol (1990) 1.46
Conditions that induce tolerance in mature CD4+ T cells. J Exp Med (1997) 1.45
Structural studies on the murine Ia alloantigens--III. Tryptic peptide comparisons of allelic products of the I-E/C sub-region. Mol Immunol (1979) 1.42
Mitogenic effect of a water-soluble extract of Nocardia opaca: a comparative study with some bacterial adjuvants on spleen and peripheral lymphocytes of four mammalian species. J Immunol (1974) 1.40
Structure, function, and genetics of human class II molecules. Adv Immunol (1985) 1.39
Primary structural variation among serologically indistinguishable DS antigens: the MB3-bearing molecule in DR4 cells differs from the MB3-bearing molecule in DR5 cells. J Immunol (1984) 1.38
Target cells for the activity of a synthetic adjuvant: muramyl dipeptide. Cell Immunol (1977) 1.36
Cold-reactive rheumatoid factors in infectious mononucleosis and other diseases. Arthritis Rheum (1969) 1.35
Immune response to levan. III. The capacity to produce anti-inulin antibodies and cross-reactive idiotypes appears late in ontogeny. J Immunol (1979) 1.34
Structural studies on the murine Ia alloantigens. V. Evidence that the structural gene for the I-E/C beta polypeptide is encoded within the I-A subregion. J Exp Med (1979) 1.34
A human T-independent B lymphocyte mitogen extracted from Nocardia opaca. J Immunol (1976) 1.33
Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptide. J Clin Invest (1988) 1.32
Hypergammaglobulinemic purpura. Studies on the unusual anti- -globulins characteristic of the sera of these patients. Medicine (Baltimore) (1971) 1.32
Production and characterization of recombinant human Ku antigen. Nucleic Acids Res (1994) 1.32
Phylogenetically associated residues within the VH3 subgroup of several mammalian species. Evidence for a "pauci-gene" basis for antibody diversity. J Exp Med (1973) 1.31
VH sequence of a human anti-Sm autoantibody. Evidence that autoantibodies can be unmutated copies of germline genes. J Immunol (1989) 1.30
Staphylococcal protein A simultaneously interacts with framework region 1, complementarity-determining region 2, and framework region 3 on human VH3-encoded Igs. J Immunol (1996) 1.29
Protein-nucleotide contacts in the immunoglobulin heavy-chain promoter region. Proc Natl Acad Sci U S A (1987) 1.29
Structural studies on the murine Ia alloantigens. IV. NH2-terminal sequence analysis of allelic products of the I-A and I-E/C subregions. J Immunol (1979) 1.28
Localization of two additional hypervariable regions in immunoglobulin heavy chains. Proc Natl Acad Sci U S A (1971) 1.27
Blast transformation of rabbit B-derived lymphocytes by a mitogen extracted from Nocardia. J Immunol (1975) 1.25
Novel rearrangements at the immunoglobulin D locus. Inversions and fusions add to IgH somatic diversity. J Exp Med (1989) 1.25
Use of antipeptide antibodies to demonstrate external orientation of the NH2-terminus of the low density lipoprotein receptor in the plasma membrane of fibroblasts. J Cell Biol (1983) 1.25
Neonatal treatment with low doses of anti-idiotypic antibody leads to the expression of a silent clone. J Exp Med (1981) 1.24
Complete amino acid sequence of light chain variable regions derived from five monoclonal anti-p-azophenylarsonate antibodies differing with respect to a crossreactive idiotype. Proc Natl Acad Sci U S A (1981) 1.24
VH4-21, a human VH gene segment overrepresented in the autoimmune repertoire. Arthritis Rheum (1992) 1.23
Amino acid sequence diversity within the family of antibodies bearing the major antiarsonate cross-reactive idiotype of the A strain mouse. J Exp Med (1983) 1.22
[Serological evolution of infection by Plasmodium malariae: variations of fluorescent antibody titre after radical treatment]. Bull World Health Organ (1969) 1.22
Organization of the murine immunoglobulin VH complex in the inbred strains. EMBO J (1987) 1.22
Structural analysis of a human I-A homologue using a monoclonal antibody that recognizes an MB3-like specificity. J Exp Med (1983) 1.21
The amino acid sequence of the variable regions of the light chains from two idiotypically cross reactive IgM anti-gamma globulins. Ann Immunol (Paris) (1976) 1.20
An incomplete cold-reactive gamma G antibody with i specificity in infectious mononucleosis. Vox Sang (1969) 1.20
Junctional diversity is essential to antibody activity. J Immunol (1984) 1.20
Induction of somatic mutation in a human B cell line in vitro. Immunity (1997) 1.19
Murine V kappa gene expression does not follow the VH paradigm. J Exp Med (1989) 1.19
Primary structure of the porin protein of Haemophilus influenzae type b determined by nucleotide sequence analysis. Infect Immun (1989) 1.19
Polyclonal activation of human B lymphocytes by Nocardia water soluble mitogen (NWSM). Immunol Rev (1979) 1.19
The human HLA-DR antigens are encoded by multiple beta-chain loci. J Immunol (1982) 1.19
Cell suppression in PPD-induced blast specific response of human peripheral blood lymphocytes. Clin Exp Immunol (1976) 1.18
Use of JH4 joining segment gene by an anti-arsonate antibody that bears the major A-strain cross-reactive idiotype but displays diminished antigen binding. J Immunol (1984) 1.18
Presence and subcellular localization of two distinct mitogenic fractions in the cells of Nocardia rubra and Nocardia opaca: preparation of soluble mitogenic peptidoglycan fractions. Infect Immun (1976) 1.18
The fluorescent antibody technique in the estimation of immunity in patients infected with Plasmodium malariae. Trans R Soc Trop Med Hyg (1966) 1.17
Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid. Eur J Immunol (1992) 1.17
[The value of the immunofluorescent reaction in the detection of asymptomatic parasitemia due to Plasmodium malariae]. Bull World Health Organ (1967) 1.17
VH families in the antibody response to p-azophenylarsonate: correlation between serology and amino acid sequence. J Immunol (1982) 1.17
A human Ro/SS-A autoantigen is the homologue of calreticulin and is highly homologous with onchocercal RAL-1 antigen and an aplysia "memory molecule". J Clin Invest (1990) 1.17