Published in Biochem Biophys Res Commun on April 29, 1987
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily. Proc Natl Acad Sci U S A (1990) 2.09
Identification and characterization of a mitogen-activated S6 kinase. Proc Natl Acad Sci U S A (1988) 2.06
Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase. Mol Cell Biol (1989) 1.96
Identification of Xenopus S6 protein kinase homologs (pp90rsk) in somatic cells: phosphorylation and activation during initiation of cell proliferation. Mol Cell Biol (1990) 1.87
Regulation of pp90rsk phosphorylation and S6 phosphotransferase activity in Swiss 3T3 cells by growth factor-, phorbol ester-, and cyclic AMP-mediated signal transduction. Mol Cell Biol (1991) 1.51
Identification of mitogen-responsive ribosomal protein S6 kinase pp90rsk, a homolog of Xenopus S6 kinase II, in chicken embryo fibroblasts. Mol Cell Biol (1990) 1.35
A stimulated S6 kinase from rat liver: identity with the mitogen activated S6 kinase of 3T3 cells. EMBO J (1989) 1.22
Two distinct enzymes contribute to biphasic S6 phosphorylation in serum-stimulated chicken embryo fibroblasts. Mol Cell Biol (1990) 1.20
Coinfection of insect cells with recombinant baculovirus expressing pp60v-src results in the activation of a serine-specific protein kinase pp90rsk. Proc Natl Acad Sci U S A (1990) 1.09
Identical Mr 70,000 S6 kinase is activated biphasically by epidermal growth factor: a phosphopeptide that characterizes the late phase. Proc Natl Acad Sci U S A (1990) 1.00
Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation. Biochem J (1990) 0.93
Abnormal regulation of ribosomal protein S6 kinase by insulin in skeletal muscle of insulin-resistant humans. J Clin Invest (1993) 0.75
Endotoxicosis induced by Coxiella burnetii lipopolysaccharide stimulates a ribosomal protein S6 kinase: some properties of the partially purified enzyme. Infect Immun (1989) 0.75
Protein phosphorylation. Annu Rev Biochem (1975) 6.71
Respiratory effects are associated with the number of ultrafine particles. Am J Respir Crit Care Med (1997) 5.35
Development of hormone receptors and hormonal responsiveness in vitro. Insulin receptors and insulin sensitivity in the preadipocyte and adipocyte forms of 3T3-L1 cells. J Biol Chem (1978) 4.93
Cloning and characterization of a cDNA encoding the rat brain glucose-transporter protein. Proc Natl Acad Sci U S A (1986) 4.40
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J Biol Chem (1987) 4.32
Phosphorylation activates the insulin receptor tyrosine protein kinase. Proc Natl Acad Sci U S A (1983) 3.94
After insulin binds. Science (1987) 3.16
Daily mortality and fine and ultrafine particles in Erfurt, Germany part I: role of particle number and particle mass. Res Rep Health Eff Inst (2000) 2.85
Air pollution and daily mortality in Erfurt, east Germany, 1980-1989. Environ Health Perspect (1993) 2.84
Effect of dibutyryladenosine 3':5'-cyclic monophosphate on growth and differentiation in Caulobacter crescentus. Proc Natl Acad Sci U S A (1972) 2.73
Respiratory health and individual estimated exposure to traffic-related air pollutants in a cohort of young children. Occup Environ Med (2006) 2.55
Traffic-related air pollution and respiratory health during the first 2 yrs of life. Eur Respir J (2002) 2.50
Age of entry to day nursery and allergy in later childhood. Lancet (1999) 2.42
Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta. Proc Natl Acad Sci U S A (1982) 2.40
The European Community Respiratory Health Survey: what are the main results so far? European Community Respiratory Health Survey II. Eur Respir J (2001) 2.35
Organelle relationships in cultured 3T3-L1 preadipocytes. J Cell Biol (1980) 2.30
Increase in diagnosed asthma but not in symptoms in the European Community Respiratory Health Survey. Thorax (2004) 2.23
Acquisition of increased hormone sensitivity during in vitro adipocyte development. J Biol Chem (1977) 2.23
Early life origins of chronic obstructive pulmonary disease. Thorax (2009) 2.20
Asthma is associated with single-nucleotide polymorphisms in ADAM33. Clin Exp Allergy (2004) 2.20
Fate of immunoprecipitable protein kinase C in GH3 cells treated with phorbol 12-myristate 13-acetate. J Biol Chem (1985) 2.15
Molecular forms and subunit composition of a cyclic adenosine 3',5'-monophosphate-dependent protein kinase purified from bovine heart muscle. J Biol Chem (1972) 1.99
Glucose transporters serve as water channels. Proc Natl Acad Sci U S A (1990) 1.95
The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential. EMBO J (1995) 1.93
Impact of early feeding on childhood eczema: development after nutritional intervention compared with the natural course - the GINIplus study up to the age of 6 years. Clin Exp Allergy (2010) 1.90
Activation of S6 kinase activity in 3T3-L1 cells by insulin and phorbol ester. Proc Natl Acad Sci U S A (1985) 1.89
Cigar and pipe smoking and lung cancer risk: a multicenter study from Europe. J Natl Cancer Inst (1999) 1.88
Glucose deprivation and hexose transporter polypeptides of murine fibroblasts. J Biol Chem (1986) 1.81
Short-term effects of particulate air pollution on respiratory morbidity in asthmatic children. Eur Respir J (1997) 1.80
Cyclic adenosine 3',5'-monophosphate-dependent protein kinase of human erythrocyte membranes. J Biol Chem (1972) 1.80
Genome-wide association study of body mass index in 23 000 individuals with and without asthma. Clin Exp Allergy (2013) 1.74
Cyclic 3':5'-adenosine monophosphate in Escherichia coli during transient and catabolite repression. Proc Natl Acad Sci U S A (1974) 1.71
Transformation of rat fibroblasts by FSV rapidly increases glucose transporter gene transcription. Science (1987) 1.70
Underestimation of airflow obstruction among young adults using FEV1/FVC <70% as a fixed cut-off: a longitudinal evaluation of clinical and functional outcomes. Thorax (2008) 1.68
C-reactive protein and the severity of atherosclerosis in myocardial infarction patients with stable angina pectoris. Eur Heart J (2000) 1.63
Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6. Proc Natl Acad Sci U S A (1983) 1.59
Description of a protein kinase derived from insulin-treated 3T3-L1 cells that catalyzes the phosphorylation of ribosomal protein S6 and casein. J Biol Chem (1983) 1.59
In vivo telomere dynamics of human hematopoietic stem cells. Proc Natl Acad Sci U S A (1997) 1.58
Purification and properties of the human placental insulin receptor. J Biol Chem (1981) 1.57
Acute health effects of exposure to high levels of air pollution in eastern Europe. Am J Epidemiol (1996) 1.56
Prospective association between food sensitization and food allergy: results of the LISA birth cohort study. Clin Exp Allergy (2009) 1.55
Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life. Allergy (2009) 1.54
Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation. J Biol Chem (1986) 1.54
Insulin-treated 3T3-L1 adipocytes and cell-free extracts derived from them incorporate 32P into ribosomal protein S6. Proc Natl Acad Sci U S A (1980) 1.53
Growth factors rapidly induce expression of the glucose transporter gene. J Biol Chem (1988) 1.53
The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. J Biol Chem (1987) 1.52
Increased asthma medication use in association with ambient fine and ultrafine particles. Eur Respir J (2002) 1.51
Insulin receptor is an insulin-dependent tyrosine protein kinase: copurification of insulin-binding activity and protein kinase activity to homogeneity from human placenta. Proc Natl Acad Sci U S A (1984) 1.49
Hemostasis in normotensive and hypertensive men: results of the PROCAM study. The prospective cardiovascular Münster study. J Hypertens (1998) 1.48
D-dimers in relation to the severity of arteriosclerosis in patients with stable angina pectoris after myocardial infarction. Eur Heart J (1999) 1.48
Association of the GPIa C807T and GPIIIa PlA1/A2 polymorphisms with premature myocardial infarction in men. Eur Heart J (2002) 1.47
Characterization of antisera to a synthetic carboxyl-terminal peptide of the glucose transporter protein. J Biol Chem (1988) 1.42
Insulin-stimulated protein phosphorylation in 3T3-L1 preadipocytes. Proc Natl Acad Sci U S A (1979) 1.41
Increasing the cAMP content of IM-9 cells alters the phosphorylation state and protein kinase activity of the insulin receptor. J Biol Chem (1986) 1.41
Medication use modifies the health effects of particulate sulfate air pollution in children with asthma. Environ Health Perspect (1997) 1.40
Phosphorylation of a cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1974) 1.40
Reversible autophosphorylation of a cyclic 3':5'-AMP-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1975) 1.40
Observation of B(0)(s)-->Psi(2S)Phi and measurement of the ratio of branching fractions Beta(B(0)(s)-->Psi(2S)Phi)/Beta(B(0)(s)-->J/PsiPhi). Phys Rev Lett (2006) 1.40
Integration of biological and nursing sciences: a 10-year plan to enhance research and training. Res Nurs Health (1993) 1.39
MSL1 plays a central role in assembly of the MSL complex, essential for dosage compensation in Drosophila. EMBO J (2000) 1.38
Soluble cyclic AMP-dependent protein kinases: review of the enzyme isolated from bovine cardiac muscle. Curr Top Cell Regul (1977) 1.37
Cyclic AMP-dependent protein kinase from bovine heart muscle. Methods Enzymol (1974) 1.35
Precursor of C4 antisense RNA of bacteriophages P1 and P7 is a substrate for RNase P of Escherichia coli. Proc Natl Acad Sci U S A (1995) 1.33
The effect of nucleotides and a nondialyzable factor on the hydrolysis of cyclic AMP by a cyclic nucleotide phosphodiesterase from beef heart. Arch Biochem Biophys (1971) 1.32
Precision top-quark mass measurement at CDF. Phys Rev Lett (2012) 1.30
Studies on the orientation of cyclic AMP-dependent protein kinase in human erythrocyte membranes. Proc Natl Acad Sci U S A (1973) 1.29
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid. J Biol Chem (1988) 1.29
Sources and elemental composition of ambient PM(2.5) in three European cities. Sci Total Environ (2005) 1.28
Dissociation and reassociation of the phosphorylated and nonphosphorylated forms of adenosine 3':5' -monophosphate-dependent protein kinase from bovine cardiac muscle. J Biol Chem (1976) 1.28
Phosphorylation of exogenous substrates by the insulin receptor-associated protein kinase. J Biol Chem (1983) 1.28
Risk factors for lung cancer in young adults. Am J Epidemiol (1998) 1.27
Geldanamycin abrogates ErbB2 association with proteasome-resistant beta-catenin in melanoma cells, increases beta-catenin-E-cadherin association, and decreases beta-catenin-sensitive transcription. Cancer Res (2001) 1.27
Phorbol ester- and protein kinase C-mediated phosphorylation of the cellular Kirsten ras gene product. J Biol Chem (1987) 1.26
Exposure to endotoxin decreases the risk of atopic eczema in infancy: a cohort study. J Allergy Clin Immunol (2001) 1.25
Purification and properties of a specific fructose 1,6-diphosphatase from Candida utilis. Arch Biochem Biophys (1965) 1.25
Properties of an adenyl cyclase partially purified from frog erythrocytes. Arch Biochem Biophys (1969) 1.24
Development of hormone receptors and hormone responsiveness in vitro. Effect of prolonged insulin treatment on hexose uptake in 3T3-L1 adipocytes. J Biol Chem (1978) 1.23
MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine. Allergy (2011) 1.22
Measurement of the cross section for prompt isolated diphoton production using the full CDF run II data sample. Phys Rev Lett (2013) 1.22
Long-term exposure to traffic-related air pollution and insulin resistance in children: results from the GINIplus and LISAplus birth cohorts. Diabetologia (2013) 1.22
What defines airflow obstruction in asthma? Eur Respir J (2009) 1.22
Elemental composition and sources of fine and ultrafine ambient particles in Erfurt, Germany. Sci Total Environ (2003) 1.22
Biosynthetic precursors and in vitro translation products of the glucose transporter of human hepatocarcinoma cells, human fibroblasts, and murine preadipocytes. J Biol Chem (1985) 1.22
Air quality in postunification Erfurt, East Germany: associating changes in pollutant concentrations with changes in emissions. Environ Health Perspect (2001) 1.20
Nuclear transport of U1 snRNP in somatic cells: differences in signal requirement compared with Xenopus laevis oocytes. J Cell Biol (1994) 1.20
Interconversion of cyclic nucleotide-activated and cyclic nucleotide-independent forms of a protein kinase from beef heart. Proc Natl Acad Sci U S A (1971) 1.20
Epidemiology of food allergy/food intolerance in adults: associations with other manifestations of atopy. Allergy (2001) 1.20
Tunicamycin-mediated depletion of insulin receptors in 3T3-L1 adipocytes. J Cell Physiol (1979) 1.19
Associations between mortality and air pollution in central Europe. Environ Health Perspect (2000) 1.19
Prevalence of respiratory symptoms, bronchial hyperresponsiveness and atopy among adults: west and east Germany. Eur Respir J (1996) 1.18
Chronic bronchitis and urban air pollution in an international study. Occup Environ Med (2006) 1.18
Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo. J Biol Chem (1986) 1.17
Effects of fine and ultrafine particles on cardiorespiratory symptoms in elderly subjects with coronary heart disease: the ULTRA study. Am J Epidemiol (2003) 1.17
Physical properties of a purified cyclic adenosine 3':5'-monophosphate-dependent protein kinase from bovine heart muscle. J Biol Chem (1973) 1.17
Comparison of parental reports of smoking and residential air nicotine concentrations in children. Occup Environ Med (2006) 1.17
Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody. Proc Natl Acad Sci U S A (1986) 1.15
The internal burden of lead among children in a smelter town--a small area analysis. Environ Res (1997) 1.15