Published in Inflammation on December 01, 1977
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell (2009) 4.69
Neutrophil aggregation and degranulation. Effect of arachidonic acid. Am J Pathol (1979) 1.15
A possible role of arachidonic acid in human neutrophil aggregation and degranulation. Am J Pathol (1979) 1.06
Lower torso ischemia-induced lung injury is leukocyte dependent. Ann Surg (1988) 1.02
Acute generalized microvascular injury by activated complement and hypoxia: the basis of the adult respiratory distress syndrome and multiple organ failure? Br J Exp Pathol (1986) 0.86
Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes. Ann Surg (1988) 0.85
Effects of anti-rheumatic herbal medicines on cellular adhesion molecules. Ann Rheum Dis (1999) 0.84
Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides. Proc Natl Acad Sci U S A (1975) 10.82
Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science (1983) 9.51
Leukotrienes and lipoxins: structures, biosynthesis, and biological effects. Science (1987) 8.36
Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets. Proc Natl Acad Sci U S A (1974) 8.30
Isolation and structure of two prostaglandin endoperoxides that cause platelet aggregation. Proc Natl Acad Sci U S A (1974) 7.00
Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187. Proc Natl Acad Sci U S A (1979) 6.34
Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis. J Clin Invest (1975) 6.25
Leukotriene C: a slow-reacting substance from murine mastocytoma cells. Proc Natl Acad Sci U S A (1979) 5.33
Mechanisms of lysosomal enzyme release from human leukocytes: microtubule assembly and membrane fusion induced by a component of complement. Proc Natl Acad Sci U S A (1973) 4.58
Detection and isolation of an endoperoxide intermediate in prostaglandin biosynthesis. Proc Natl Acad Sci U S A (1973) 4.43
Studies on lysosomes. XI. Characterization of a hydrolase-rich fraction from human lymphocytes. J Cell Biol (1968) 4.22
Prostaglandin endoperoxides. A new concept concerning the mode of action and release of prostaglandins. Proc Natl Acad Sci U S A (1974) 4.10
Effect of cyclic AMP on release of lysosomal enzymes from phagocytes. Nat New Biol (1971) 4.09
Leukotrienes are potent constrictors of human bronchi. Nature (1980) 4.04
Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases. J Biol Chem (1976) 3.82
Mechanisms of lysosomal enzyme release from human leukocytes. II. Effects of cAMP and cGMP, autonomic agonists, and agents which affect microtubule function. J Clin Invest (1974) 3.65
Cytochalasin B: effect on lysosomal enzyme release from human leukocytes. Proc Natl Acad Sci U S A (1973) 3.63
Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A (1999) 3.61
Prostaglandins and thromboxanes. Annu Rev Biochem (1978) 3.47
Leukotrienes promote plasma leakage and leukocyte adhesion in postcapillary venules: in vivo effects with relevance to the acute inflammatory response. Proc Natl Acad Sci U S A (1981) 3.42
Formation of malonaldehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem (1968) 3.41
Mechanisms of lysosomal enzyme release from leukocytes exposed to immune complexes and other particles. J Exp Med (1971) 3.38
Release of inflammatory mediators from stimulated neutrophils. N Engl J Med (1980) 3.35
On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase. J Biol Chem (1967) 3.30
Calcium-induced lysozyme secretion from human polymorphonuclear leukocytes. Biochem Biophys Res Commun (1974) 3.24
Transformation of arachidonic acid by rabbit polymorphonuclear leukocytes. Formation of a novel dihydroxyeicosatetraenoic acid. J Biol Chem (1979) 3.16
Arachidonic acid metabolism in polymorphonuclear leukocytes: unstable intermediate in formation of dihydroxy acids. Proc Natl Acad Sci U S A (1979) 3.14
Metabolism of arachidonic acid in polymorphonuclear leukocytes. Structural analysis of novel hydroxylated compounds. J Biol Chem (1979) 3.08
Oxygenation of unsaturated fatty acids by the vesicular gland of sheep. J Biol Chem (1967) 2.93
Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature (1976) 2.83
A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci U S A (1992) 2.79
Leukotriene D: a slow reacting substance from rat basophilic leukemia cells. Proc Natl Acad Sci U S A (1980) 2.77
Evidence that the superoxide-generating system of human leukocytes is associated with the cell surface. J Clin Invest (1977) 2.77
Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis. Proc Natl Acad Sci U S A (1975) 2.75
Lysosomal enzyme release from human leukocytes: mediation by the alternate pathway of complement activation. J Immunol (1973) 2.66
Prostaglandin endoperoxides. VII. Novel transformations of arachidonic acid in guinea pig lung. Biochem Biophys Res Commun (1974) 2.56
Lysosome. N Engl J Med (1965) 2.49
Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes. Proc Natl Acad Sci U S A (1984) 2.46
Changes in membrane potential of human granulocytes antecede the metabolic responses to surface stimulation. Proc Natl Acad Sci U S A (1978) 2.33
Mechanisms of lysosomal enzyme release from human leukocytes. I. Effect of cyclic nucleotides and colchicine. J Cell Biol (1973) 2.33
Interaction of alytic polypeptide, melittin, with lipid membrane systems. J Biol Chem (1969) 2.31
Effect of cyclic 3',5'-adenosine monophosphate and theophylline on lymphocyte transformation. Proc Soc Exp Biol Med (1970) 2.30
Structure of leukotriene C. Identification of the amino acid part. Biochem Biophys Res Commun (1979) 2.30
Tumor necrosis factor provokes superoxide anion generation from neutrophils. Biochem Biophys Res Commun (1986) 2.27
Leukocytic proteases and the immunologic release of lysosomal enzymes. Am J Pathol (1972) 2.26
Biosynthesis of prostaglandins. Fed Proc (1972) 2.23
Biosynthesis of prostaglandins from arachidonic acid in guinea pig lung. Prostaglandins and related factors. 38. J Biol Chem (1965) 2.23
Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. J Exp Med (1983) 2.18
Potassium and amino acid transport in human leukocytes exposed to phagocytic stimuli. J Cell Biol (1974) 2.16
Effects of cholera enterotoxin on adenosine 3',5'-monophosphate and neutrophil function. Comparison with other compounds which stimulate leukocyte adenyl cyclase. J Clin Invest (1973) 2.16
The action of steroids and streptolysin S on the permeability of phospholipid structures to cations. J Mol Biol (1965) 2.10
Prostaglandins. Annu Rev Biochem (1975) 2.09
Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes. J Cell Biol (1976) 2.08
Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc Natl Acad Sci U S A (1984) 2.05
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence. Blood (1981) 2.05
Identification and biological activity of novel omega-oxidized metabolites of leukotriene B4 from human leukocytes. FEBS Lett (1981) 2.04
Generation of C5-derived lysosomal enzyme-releasing activity (C5a) by lysates of leukocyte lysosomes. J Immunol (1974) 2.02
On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha. J Biol Chem (1967) 2.02
Formation of leukotrienes and other hydroxy acids during platelet-neutrophil interactions in vitro. Biochem Biophys Res Commun (1982) 2.02
Breakdown of cartilage proteinpolysaccharide by lysosomes. Arthritis Rheum (1968) 1.99
Independent effects of IgG and complement upon human polymorphonuclear leukocyte function. J Immunol (1976) 1.97
Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A (1986) 1.97
The chemical composition of the cytoplasmic membrane of Bacillus subtilis. Eur J Biochem (1967) 1.96
Adenosine; a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol (1985) 1.96
On the nature of the 5-lipoxygenase reaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. Proc Natl Acad Sci U S A (1985) 1.91
Prostaglandins in human seminal plasma. Prostaglandins and related factors 46. J Biol Chem (1966) 1.91
Lysosomes and joint disease. Arthritis Rheum (1966) 1.90
Phospholipid precursors of prostaglandins. Biochim Biophys Acta (1968) 1.90
Phospholipid spherules (liposomes) as a model for biological membranes. J Lipid Res (1968) 1.89
Prostaglandin endoperoxides IV. Effects on smooth muscle. Life Sci (1975) 1.89
Mechanisms of lysosomal enzyme release from human polymorphonuclear leukocytes. Effects of phorbol myristate acetate. J Cell Biol (1975) 1.87
Neutrophil adherence to endothelium is enhanced via adenosine A1 receptors and inhibited via adenosine A2 receptors. J Immunol (1992) 1.84
Ceruloplasmin. A scavenger of superoxide anion radicals. J Biol Chem (1979) 1.84
Stimulus response coupling in the human neutrophil. II. Temporal analysis of changes in cytosolic calcium and calcium efflux. J Biol Chem (1984) 1.84
The adhesion molecules of inflammation. Arthritis Rheum (1993) 1.83
Lysosomal mechanisms of tissue injury in arthritis. N Engl J Med (1972) 1.81
The role of lysosomes in inflammation and disease. Annu Rev Med (1967) 1.76
Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells. J Clin Invest (1986) 1.76
A general method for the introduction of enzymes, by means of immunoglobulin-coated liposomes, into lysosomes of deficient cells. Proc Natl Acad Sci U S A (1975) 1.76
Degranulation, membrane addition, and shape change during chemotactic factor-induced aggregation of human neutrophils. J Cell Biol (1982) 1.75
Physiological role of an endoperoxide in human platelets: hemostatic defect due to platelet cyclo-oxygenase deficiency. Proc Natl Acad Sci U S A (1975) 1.74
Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils. Science (1993) 1.72
On the metabolism of prostaglandins E 1 and E 2 in man. J Biol Chem (1971) 1.71
Leukotriene A4 hydrolase in human leukocytes. Purification and properties. J Biol Chem (1984) 1.70
Role of microtubule assembly in lysosomal enzyme secretion from human polymorphonuclear leukocytes. A reevaluation. J Cell Biol (1977) 1.69
Leukotriene B4 is a complete secretagogue in human neutrophils: a kinetic analysis. Biochem Biophys Res Commun (1982) 1.69
Reciprocal effects of cAMP and cGMP on microtubule-dependent release of lysosomal enzymes. Ann N Y Acad Sci (1975) 1.68
The action of polyene antibiotics on phospholipid-cholesterol structures. J Biol Chem (1967) 1.67