Published in J Biol Chem on March 25, 1978
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol (1986) 5.96
Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol (1984) 4.00
Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization. J Cell Biol (1982) 3.80
Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Natl Acad Sci U S A (1979) 3.79
Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol (1982) 3.47
Keratin cytoskeletons in epithelial cells of internal organs. Proc Natl Acad Sci U S A (1979) 3.45
Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation. J Cell Biol (1988) 2.88
Use of monoclonal antibodies for the histopathological diagnosis of human malignancy. J Clin Pathol (1982) 2.69
Retinoids as important regulators of terminal differentiation: examining keratin expression in individual epidermal cells at various stages of keratinization. J Cell Biol (1987) 2.62
The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J Cell Biol (1983) 2.58
Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J Cell Biol (1984) 2.48
Monoclonal antibodies to intermediate filament proteins of human cells: unique and cross-reacting antibodies. J Cell Biol (1982) 2.45
Antibodies to neurofilament, glial filament, and fibroblast intermediate filament proteins bind to different cell types of the nervous system. J Cell Biol (1981) 2.41
Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides. J Cell Biol (1985) 2.37
Subcellular localization of glycoproteins encoded by the viral oncogene v-fms. J Virol (1984) 2.21
Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat (2009) 2.21
Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. J Cell Biol (1982) 1.93
Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. J Cell Biol (1986) 1.91
The role of cytoskeletal and cytocontractile elements in pathologic processes. Am J Pathol (1983) 1.91
Evidence for posttranscriptional regulation of the keratins expressed during hyperproliferation and malignant transformation in human epidermis. J Cell Biol (1986) 1.89
Elucidating the early stages of keratin filament assembly. J Cell Biol (1990) 1.80
Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene. Proc Natl Acad Sci U S A (1985) 1.78
Tissue specificity of epithelial keratins: differential expression of mRNAs from two multigene families. Mol Cell Biol (1983) 1.75
The fibrillar substructure of keratin filaments unraveled. J Cell Biol (1983) 1.75
Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A (1983) 1.64
Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin. Proc Natl Acad Sci U S A (1983) 1.61
Isolation, sequence, and expression of a human keratin K5 gene: transcriptional regulation of keratins and insights into pairwise control. Mol Cell Biol (1989) 1.56
A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells. EMBO J (1982) 1.54
The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes. Proc Natl Acad Sci U S A (1985) 1.52
Isolation and characterization of desmosome-associated tonofilaments from rat intestinal brush border. J Cell Biol (1981) 1.52
Tissue type-specific expression of intermediate filament proteins in a cultured epithelial cell line from bovine mammary gland. J Cell Biol (1983) 1.46
Differentiation of human epidermal cells transformed by SV40. J Cell Biol (1983) 1.45
Disease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex. Proc Natl Acad Sci U S A (1993) 1.41
Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes. Mol Cell Biol (1986) 1.33
Keratin alterations during embryonic epidermal differentiation: a presage of adult epidermal maturation. J Cell Biol (1982) 1.28
Modification of human prekeratin during epidermal differentiation. Biochem J (1981) 1.27
A group of type I keratin genes on human chromosome 17: characterization and expression. Mol Cell Biol (1988) 1.27
The use of retinoic acid to probe the relation between hyperproliferation-associated keratins and cell proliferation in normal and malignant epidermal cells. J Cell Biol (1989) 1.25
Identification of mouse mammary epithelial cells by immunofluorescence with rabbit and guinea pig antikeratin antisera. Proc Natl Acad Sci U S A (1981) 1.23
Salivary gland components involved in the formation of squamous metaplasia. Am J Pathol (1985) 1.18
Differences of expression of cytokeratin polypeptides in various epithelial skin tumors. Arch Dermatol Res (1984) 1.18
Pairwise assembly determines the intrinsic potential for self-organization and mechanical properties of keratin filaments. Mol Biol Cell (2002) 1.17
Expression of keratin and vimentin intermediate filaments in rabbit bladder epithelial cells at different stages of benzo[a]pyrene-induced neoplastic progression. J Cell Biol (1981) 1.16
Intermediate filaments. J Cell Biol (1984) 1.14
Characterisation of the rat oesophagus epithelium antigens defined by the so-called 'antikeratin antibodies', specific for rheumatoid arthritis. Ann Rheum Dis (1993) 1.13
Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Mol Biol (2012) 1.10
Purification and characterization of a 27,000-Mr extracellular proteinase from Trichophyton rubrum. Infect Immun (1989) 1.09
Isolation and characterization of two polypeptides that form intermediate filaments in bovine esophageal epithelium. J Cell Biol (1981) 1.09
Mesosecrin: a secreted glycoprotein produced in abundance by human mesothelial, endothelial, and kidney epithelial cells in culture. J Cell Biol (1987) 1.08
Preferential phosphorylation of the 150,000 molecular weight component of neurofilaments by a cyclic AMP-dependent, microtubule-associated protein kinase. J Cell Biol (1981) 1.02
Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland. J Cell Biol (1981) 1.01
Cytokeratin No. 9, an epidermal type I keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity. J Cell Biol (1986) 1.00
Role of disulfide bonds in maintaining the structural integrity of the sheath of Leptothrix discophora SP-6. J Bacteriol (1993) 0.99
Prekeratin biosynthesis in human scalp epidermis. Biochem J (1982) 0.97
Intermediate filament cytoskeleton of amnion epithelium and cultured amnion epithelial cells: expression of epidermal cytokeratins in cells of a simple epithelium. J Cell Biol (1985) 0.97
Dual regulation of intermediate filament phosphorylation. J Cell Biol (1984) 0.96
Malignant progression of an SV40-transformed human epidermal keratinocyte cell line. Br J Cancer (1987) 0.96
Identification of a stem cell candidate in the normal human prostate gland. Eur J Cell Biol (2005) 0.95
Keratin polypeptide modifications induced by human papilloma viruses (HPV). Arch Dermatol Res (1981) 0.93
Cultured human amniotic fluid cells characterized with antibodies against intermediate filaments in indirect immunofluorescence microscopy. J Clin Invest (1981) 0.92
Proteins IEF (isoelectric focusing) 31 and IEF 46 are keratin-type components of the intermediate-sized filaments: keratins of various human cultured epithelial cells. J Cell Biol (1983) 0.92
Sequence and expression of a human type II mesothelial keratin. J Cell Biol (1985) 0.92
Epithelial markers in the diagnosis of nasopharyngeal carcinoma: an immunocytochemical study. J Clin Pathol (1983) 0.92
Keratin filaments of mouse epithelial cells are rapidly affected by epidermal growth factor. J Cell Biol (1981) 0.92
Proteolytic release of keratinocyte transglutaminase. Biochem J (1990) 0.91
Human epithelial cell intermediate filaments: isolation, purification, and characterization. J Cell Biol (1984) 0.90
Keratin polypeptide composition as a biochemical tool for the discrimination of benign and malignant epithelial lesions in man. Arch Dermatol Res (1983) 0.90
Identification of cytokeratin antigens in Novikoff ascites hepatoma. Proc Natl Acad Sci U S A (1982) 0.89
Cyanogen bromide cleavage of proteins in sodium dodecyl sulphate/polyacrylamide gels. Diagonal peptide mapping of proteins from epidermis. Biochem J (1981) 0.88
Keratin in human lung tumors. Patterns of localization of different-molecular-weight keratin proteins. Am J Pathol (1983) 0.88
The rheumatoid arthritis-associated autoantibodies to filaggrin label the fibrous matrix of the cornified cells but not the profilaggrin-containing keratohyalin granules in human epidermis. Clin Exp Immunol (1995) 0.88
Passive and iontophoretic transport enhancement of insulin through porcine epidermis by depilatories: permeability and fourier transform infrared spectroscopy studies. AAPS PharmSciTech (2003) 0.87
Convergent differentiation in cultured rat cells from nonkeratinized epithelia: keratinocyte character and intrinsic differences. J Cell Biol (1983) 0.87
A role for disulfide bonding in keratin intermediate filament organization and dynamics in skin keratinocytes. J Cell Biol (2015) 0.87
Specific quantification of mouse and human keratin proteins by radioimmunoassay. Biochem J (1980) 0.85
Fibronectin mediates adherence of rat alveolar type II epithelial cells via the fibroblastic cell-attachment domain. J Clin Invest (1986) 0.84
Complexity of expression of the intermediate filaments of six new human ovarian carcinoma cell lines: new expression of cytokeratin 20. Br J Cancer (1997) 0.84
Formation and identification of cytoskeletal components from liver cytosolic precursors. Proc Natl Acad Sci U S A (1982) 0.83
Evidence against a blood derived origin for transforming growth factor beta induced protein in corneal disorders caused by mutations in the TGFBI gene. Mol Vis (2007) 0.82
Keratin intracellular concentration revisited: implications for keratin function in surface epithelia. J Invest Dermatol (2012) 0.82
Recognition of protein apparently specific to odontogenic keratocyst fluids. J Clin Pathol (1986) 0.80
A lectin-binding glycoprotein of Mr 135,000 associated with basal keratinocytes in pig epidermis. Biochem J (1986) 0.78
Lack of antikeratin antibodies in patients with palmoplantar pustular eruptions and arthropathy. Arch Dermatol Res (1989) 0.78
Extractable immune complex in soluble substances from psoriatic scales. Arch Dermatol Res (1984) 0.78
Expression and distribution of vimentin and keratin filaments in heterokaryons of human fibroblasts and amnion epithelial cells. J Cell Biol (1982) 0.78
Biochemical and immunological characterizations of antigens recognised by human monoclonal antibodies. Br J Cancer (1989) 0.78
Assays for Posttranslational Modifications of Intermediate Filament Proteins. Methods Enzymol (2015) 0.78
Studies on the origin of human amniotic fluid cells by immunofluorescent staining of keratin filaments. J Med Genet (1982) 0.77
Keratin proteins in human lung carcinomas. Combined use of morphology, keratin immunocytochemistry, and keratin immunoprecipitation. Am J Pathol (1984) 0.77
Mathematical modeling of the impact of actin and keratin filaments on keratinocyte cell spreading. Biophys J (2012) 0.77
Directed expression of a chimeric type II keratin partially rescues keratin 5-null mice. J Biol Chem (2014) 0.76
Two different pathogenetic pathways in lichen amyloidosus and macular amyloidosis. Arch Dermatol Res (1986) 0.75
Cyclic AMP-dependent protein kinase in calf-snout epidermis. Arch Dermatol Res (1986) 0.75
Biochemical characteristics of keratins from proliferating trichilemmal cyst. Arch Dermatol Res (1984) 0.75
Polypeptide synthesis in columnar and squamous explants of human uterine cervix. Br J Exp Pathol (1982) 0.75
Stimulation of epidermal protein synthesis in vivo by topical triamcinolone acetonide. Biochem J (1987) 0.75
The Molecular Revolution in Cutaneous Biology: Keratin Genes and their Associated Disease: Diversity, Opportunities, and Challenges. J Invest Dermatol (2017) 0.75
The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease. J Invest Dermatol (2016) 0.75
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell (1975) 15.93
Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell (1990) 12.13
The initiation of cell division in a contact-inhibited mammalian cell line. J Cell Physiol (1965) 12.07
An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell (1975) 8.29
Involvement of follicular stem cells in forming not only the follicle but also the epidermis. Cell (2000) 6.93
Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell (1989) 6.49
Three clonal types of keratinocyte with different capacities for multiplication. Proc Natl Acad Sci U S A (1987) 6.30
An established pre-adipose cell line and its differentiation in culture. Cell (1974) 5.97
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells. J Cell Biol (1986) 5.96
Changes in keratin gene expression during terminal differentiation of the keratinocyte. Cell (1980) 5.83
Two types of ribosome in mouse-hamster hybrid cells. Nat New Biol (1971) 5.19
Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes. Nature (1977) 4.90
Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes. Proc Natl Acad Sci U S A (1967) 4.83
Spontaneous heritable changes leading to increased adipose conversion in 3T3 cells. Cell (1976) 4.63
Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: activation of the cross-linking by calcium ions. Cell (1979) 4.38
Immunofluorescent staining of keratin fibers in cultured cells. Cell (1978) 4.25
Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development. J Biol Chem (1983) 4.14
Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol (1984) 4.00
Growth of cultured human epidermal cells into multiple epithelia suitable for grafting. Proc Natl Acad Sci U S A (1979) 3.79
Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability. Proc Natl Acad Sci U S A (1968) 3.78
Permanent coverage of large burn wounds with autologous cultured human epithelium. N Engl J Med (1984) 3.70
Susceptibility of human diploid fibroblast strains to transformation by SV40 virus. Science (1966) 3.68
Regulation of terminal differentiation of cultured human keratinocytes by vitamin A. Cell (1981) 3.61
Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies. Cell (1982) 3.54
Cell growth and the initiation of transformation by SV40. Proc Natl Acad Sci U S A (1966) 3.50
Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol (1982) 3.47
Keratin cytoskeletons in epithelial cells of internal organs. Proc Natl Acad Sci U S A (1979) 3.45
Identification of the familial cylindromatosis tumour-suppressor gene. Nat Genet (2000) 3.42
Terminal differentiation of cultured human epidermal cells. Cell (1977) 3.39
Differentiation of the epidermal keratinocyte in cell culture: formation of the cornified envelope. Cell (1976) 3.30
Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor. Cell (1987) 3.26
Association of p63 with proliferative potential in normal and neoplastic human keratinocytes. J Invest Dermatol (1999) 3.15
High frequency of SV40 transformation of mouse cell line 3T3. Virology (1966) 3.04
Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications, and limitations. Lab Invest (1985) 3.03
The cornified envelope of terminally differentiated human epidermal keratinocytes consists of cross-linked protein. Cell (1977) 3.00
The expression of keratin genes in epidermis and cultured epidermal cells. Cell (1978) 2.87
Two distinct classes of keratin genes and their evolutionary significance. Cell (1981) 2.84
Strategies of epithelial repair: modulation of stem cell and transit amplifying cell proliferation. J Cell Sci (1998) 2.78
Structure and evolution of the human involucrin gene. Cell (1986) 2.76
Epidermal stem cells: properties, markers, and location. Proc Natl Acad Sci U S A (2000) 2.66
Cyclic AMP in relation to proliferation of the epidermal cell: a new view. Cell (1978) 2.64
The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J Cell Biol (1983) 2.58
Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J Cell Biol (1984) 2.48
Stratification and terminal differentiation of cultured epidermal cells. Nature (1982) 2.44
Involucrin synthesis and tissue assembly by keratinocytes in natural and cultured human epithelia. J Cell Biol (1981) 2.44
Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase. Science (1973) 2.37
In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infections. Proc Natl Acad Sci U S A (1996) 2.35
Cell size as a determinant of the clone-forming ability of human keratinocytes. Proc Natl Acad Sci U S A (1985) 2.34
Participation of one isozyme of cytosolic glycerophosphate dehydrogenase in the adipose conversion of 3T3 cells. J Biol Chem (1979) 2.33
Control of specific protein biosynthesis during the adipose conversion of 3T3 cells. J Biol Chem (1980) 2.33
Heterogeneity in epidermal basal keratinocytes: morphological and functional correlations. Science (1982) 2.28
Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line. J Cell Physiol (1979) 2.27
Multiple keratins of cultured human epidermal cells are translated from different mRNA molecules. Cell (1979) 2.18
Cultured epithelial cells of cornea, conjunctiva and skin: absence of marked intrinsic divergence of their differentiated states. Nature (1977) 2.17
Methyl 4-mercaptobutyrimidate as a cleavable cross-linking reagent and its application to the Escherichia coli 30S ribosome. Biochemistry (1973) 2.14
Involucrin synthesis is correlated with cell size in human epidermal cultures. J Cell Biol (1981) 2.14
Uroplakin Ia is the urothelial receptor for uropathogenic Escherichia coli: evidence from in vitro FimH binding. J Cell Sci (2001) 2.13
Intrinsic and extrinsic regulation of the differentiation of skin, corneal and esophageal epithelial cells. Cell (1980) 2.11
Ablation of uroplakin III gene results in small urothelial plaques, urothelial leakage, and vesicoureteral reflux. J Cell Biol (2000) 2.11
The nucleotide sequence of three genes participating in the adipose differentiation of 3T3 cells. J Biol Chem (1986) 2.07
Mammalian uroplakins. A group of highly conserved urothelial differentiation-related membrane proteins. J Biol Chem (1994) 2.07
Formation of a keratinizing epithelium in culture by a cloned cell line derived from a teratoma. Cell (1975) 2.06
The keratinocyte as differentiated cell type. Harvey Lect (1980) 2.04
The role of keratin subfamilies and keratin pairs in the formation of human epidermal intermediate filaments. J Cell Biol (1986) 2.04
A study of the adipose conversion of suspended 3T3 cells by using glycerophosphate dehydrogenase as differentiation marker. Proc Natl Acad Sci U S A (1979) 1.94
Differentiated cell types and the regulation of collagen synthesis. Nature (1966) 1.94
Enzymatic cross-linking of involucrin and other proteins by keratinocyte particulates in vitro. Cell (1985) 1.94
Reversible arrest of growth in G1 of an established fibroblast line (3T3). Exp Cell Res (1965) 1.92
Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins. J Cell Biol (1986) 1.91
Large scale purification and immunolocalization of bovine uroplakins I, II, and III. Molecular markers of urothelial differentiation. J Biol Chem (1990) 1.88
Increasing activity of enzymes on pathway of triacylglycerol synthesis during adipose conversion of 3T3 cells. J Biol Chem (1977) 1.86
Epidermal stem cells. J Invest Dermatol (1983) 1.86
Synthesis of collagen by mammalian cell lines of fibroblastic and nonfibroblastic origin. Proc Natl Acad Sci U S A (1965) 1.86
Participation of membrane-associated proteins in the formation of the cross-linked envelope of the keratinocyte. Cell (1984) 1.85
An assay for cellular transformation by SV40. Virology (1964) 1.84
Properties and uses of human-mouse hybrid cell lines. Nature (1968) 1.82
Adipose conversion of 3T3 cells depends on a serum factor. Proc Natl Acad Sci U S A (1978) 1.82
Studies of lipoprotein lipase during the adipose conversion of 3T3 cells. Cell (1978) 1.77
Collagen synthesis in fibroblasts transformed by oncogenic viruses. Nature (1966) 1.76
Keratin classes: molecular markers for different types of epithelial differentiation. J Invest Dermatol (1983) 1.76
The fibrillar substructure of keratin filaments unraveled. J Cell Biol (1983) 1.75
Antigenic and cultural properties of cells doubly transformed by polyoma virus and SV40. Virology (1965) 1.74
The bladder as a bioreactor: urothelium production and secretion of growth hormone into urine. Nat Biotechnol (1998) 1.71
Ribosomal RNA synthesis in human-mouse hybrid cells. J Mol Biol (1969) 1.71
Expression of epidermal keratins and filaggrin during human fetal skin development. J Cell Biol (1985) 1.68
Uroplakins Ia and Ib, two major differentiation products of bladder epithelium, belong to a family of four transmembrane domain (4TM) proteins. J Cell Biol (1994) 1.67
Induction of a deoxycytidineless state in cultured mammalian cells by bromodeoxyuridine. Cell (1974) 1.65
Cultured epithelial autografts for giant congenital nevi. Plast Reconstr Surg (1989) 1.63
Urothelium-specific expression of an oncogene in transgenic mice induced the formation of carcinoma in situ and invasive transitional cell carcinoma. Cancer Res (1999) 1.62
Stimulation of RNA synthesis and cell division in resting cells by a factor present in serum. Wistar Inst Symp Monogr (1967) 1.62
In vitro growth and differentiation of rabbit bulbar, fornix, and palpebral conjunctival epithelia. Implications on conjunctival epithelial transdifferentiation and stem cells. Invest Ophthalmol Vis Sci (1993) 1.61
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Human genetic diseases due to codon reiteration: relationship to an evolutionary mechanism. Cell (1993) 1.60
Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells. Cell (1975) 1.59
Regulation of RNA synthesis in fibroblasts during transition from resting to growing state. Proc Natl Acad Sci U S A (1973) 1.59
Somatic cell hybrid between the established human line D98 (presumptive HeLa) and 3T3. Science (1969) 1.58